Pediatrics (all articles) | Page 44 of 119 | Links Medicus Content Curation & Alerts in Medicine

[Preprint] COVID infection severity in children under 5 years old before and after Omicron emergence in the US.

21 Jan, 2022 | 10:04h | UTC

COVID infection severity in children under 5 years old before and after Omicron emergence in the US – medRxiv

Commentary: SARS-CoV-2 Omicron infections milder in children compared to Delta – News Medical

Editorial | Long covid in children and adolescents – “Risk appears low, but many questions remain”.

21 Jan, 2022 | 09:58h | UTC

Long covid in children and adolescents – The BMJ

M-A: Persistent symptoms following SARS-CoV-2 infection among children and young people – “Higher study quality was associated with lower prevalence of all symptoms, except loss of smell and cognitive symptoms”.

Review: Long COVID symptoms in children rarely persist beyond three months.

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Long COVID: the physical and mental health of children and non-hospitalized young people after SARS-CoV-2 infection – one in seven children may still have symptoms 15 weeks after infection.

Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

Cohort study: Risk factors for long covid in previously hospitalized children.

M-A: More than 50 long-term effects of COVID-19.

Commentary on Twitter

"As SARS-CoV-2 remains predominantly a mild infection in the paediatric population, the incidence of long covid is a critical factor in the risk-benefit equation for policy and parental decisions on covid-19 vaccines for children," says Editorialhttps://t.co/POidCyS2RZ

— The BMJ (@bmj_latest) January 20, 2022

ATS Guideline: Outpatient respiratory management of infants, children, and adolescents with post-prematurity respiratory disease.

21 Jan, 2022 | 09:55h | UTC

Outpatient Respiratory Management of Infants, Children, and Adolescents with Post-Prematurity Respiratory Disease: An Official American Thoracic Society Clinical Practice Guideline – American Journal of Respiratory and Critical Care Medicine

News Release: Outpatient Management of Patients with Post-Prematurity Respiratory Disease: American Thoracic Society Publishes New Clinical Practice Guideline

RCT: Lidocaine spray may reduce pain during radial arterial puncture.

21 Jan, 2022 | 09:19h | UTC

Effectiveness of lidocaine spray on radial arterial puncture pain: A randomized double-blind placebo controlled trial – The American Journal of Emergency Medicine (link to abstract – $ for full-text)

Heart function recovered quickly in children with COVID-19-related multisystem inflammatory syndrome (MIS-C).

20 Jan, 2022 | 09:26h | UTC

News Release: Heart function recovered quickly in children with COVID-19-related MIS-C condition – American Heart Association

Original Study: Longitudinal Assessment of Cardiac Outcomes of Multisystem Inflammatory Syndrome in Children Associated With COVID‐19 Infections – Journal of the American Heart Association

RCT: In very young children with Type 1 Diabetes, a hybrid closed-loop therapy (“artificial pancreas”) resulted in better glycemic control without increased risk of hypoglycemia vs. sensor-augmented pump therapy.

20 Jan, 2022 | 09:07h | UTC

Randomized Trial of Closed-Loop Control in Very Young Children with Type 1 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Artificial pancreas proves ‘life-changing’ for very young children with type 1 diabetes and their families – University of Cambridge

How do we make decisions for the most immature babies, with their families?

20 Jan, 2022 | 08:49h | UTC

How do we make decisions for the most immature babies, with their families? – Neonatal Research

Expert consensus for plasma and platelet transfusion practice in critically ill children.

20 Jan, 2022 | 08:44h | UTC

Executive Summary of Recommendations and Expert Consensus for Plasma and Platelet Transfusion Practice in Critically Ill Children: From the Transfusion and Anemia EXpertise Initiative—Control/Avoidance of Bleeding (TAXI-CAB) – Pediatric Critical Care Medicine

Systematic Review: School closures during social lockdown and mental health, health behaviors, and well-being among children and adolescents during the first Covid-19 wave.

19 Jan, 2022 | 09:00h | UTC

School Closures During Social Lockdown and Mental Health, Health Behaviors, and Well-being Among Children and Adolescents During the First COVID-19 Wave: A Systematic Review – JAMA Pediatrics

Editorial: Pandemic Recovery for Children—Beyond Reopening Schools – JAMA Pediatrics

Commentary: More Behavioral Issues Reported in Children When School Is Virtual – Psychiatric News Alert

M-A: Child and youth mental health problems have doubled during COVID-19.

Adolescents’ recreational screen time doubled during pandemic, affecting mental health.

More data on the harmful effects of the COVID-19 pandemic on the mental health of adolescents.

COVID has caused ‘mass trauma,’ worsening mental health globally.

COVID’s mental-health toll: how scientists are tracking a surge in depression

CDC Report: Mental health-related emergency department visits among children aged under 18 years raised during the COVID-19 Pandemic

WHO: COVID-19 disrupting mental health services in most countries

Commentary on Twitter (thread – click for more)

https://twitter.com/benryanwriter/status/1483482171000111111

RCT: In children with community-acquired pneumonia, outpatient antibiotic therapy for 5 days resulted in similar clinical response rates compared to a standard 10-day strategy.

19 Jan, 2022 | 08:39h | UTC

Short- vs Standard-Course Outpatient Antibiotic Therapy for Community-Acquired Pneumonia in Children: The SCOUT-CAP Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)

Commentaries:

Trial finds 5 days of antibiotics superior to 10 for kids with pneumonia – CIDRAP

Shorter antibiotics treatment is better for young children with outpatient pneumonia – Vanderbilt University Medical Center

ACP Guidance: Appropriate Use of Short-Course Antibiotics in Common Infections

RCT: 5 days of high-dose amoxicillin therapy noninferior to 10 days for the treatment of pediatric community-acquired pneumonia

RCT: Among children with community-acquired pneumonia discharged within 48 hours from the ED or hospital, lower-dose outpatient oral amoxicillin was noninferior to a higher dose, and a 3-day duration course was noninferior to 7 days.

Treatment of urinary tract infections in infants <2 Months: A Living Systematic Review – short and long duration of parenteral antibiotics were associated with a similar risk of UTI recurrence.

RCT: 7 days of antibiotic therapy as good as 14 days for afebrile men with urinary tract infection.

Randomized Trial: Seven vs. Fourteen Days of Antibiotic Therapy for Uncomplicated Gram-negative Bacteremia

Meta-Analysis: Efficacy of Short-Course Antibiotic Treatments for Community-Acquired Pneumonia

Measures implemented in the school setting to contain the COVID‐19 pandemic: a rapid review.

18 Jan, 2022 | 09:54h | UTC

Measures implemented in the school setting to contain the COVID‐19 pandemic: a rapid review – Cochrane Library

News Release: Measures implemented in the school setting to contain the COVID-19 pandemic: a rapid review – Cochrane Library

Review: Treatment of multisystem inflammatory syndrome (MIS-C) in children and adolescents.

18 Jan, 2022 | 09:46h | UTC

Treatment of MIS-C in Children and Adolescents – Current Pediatrics Reports

Review of 4,470 cases of Multisystem Inflammatory Syndrome in Children in the US.

WHO issues guidelines on the treatment of children with multisystem inflammatory syndrome associated with COVID-19.

An Update on Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2.

Ten Things to Know About Multisystem Inflammatory Syndrome in Children (MIS-C).

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.

Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.

Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.

Cohort study showed good recovery for most children 6 months after Pediatric Inflammatory Multisystem Syndrome (PIMS-TS) associated with SARS-CoV-2.

Epidemiology of Multisystem Inflammatory Syndrome in Children: A Step Closer to Understanding Who, Where, and When

Neurologic involvement in children and adolescents with COVID-19 or Multisystem Inflammatory Syndrome

Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children

Differences in characteristics and outcomes of children and adolescents with Multisystem Inflammatory Syndrome in Children (MIS-C) vs. severe acute COVID-19

Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)

SR: Multisystem inflammatory syndrome in children related to COVID-19

Observational study: The combination of Immunoglobulins + Methylprednisolone was associated with a better course of fever compared to Immunoglobulins alone in Multisystem Inflammatory Syndrome in children

ACR Guidance for pediatric patients with multisystem inflammatory syndrome in children associated with SARS‐CoV‐2

New systematic review of Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 infection summarizes the clinical features, management, and outcomes of the disease, showing favorable outcomes for the majority of children

Systematic Review: Foot orthoses for treating pediatric flat feet.

18 Jan, 2022 | 09:16h | UTC

Foot orthoses for treating paediatric flat feet – Cochrane Library

Summary: Foot orthoses for treating flat feet in children – Cochrane Library

RCT: Sirolimus plus prednisolone vs. sirolimus monotherapy for kaposiform hemangioendothelioma.

18 Jan, 2022 | 09:08h | UTC

Sirolimus plus prednisolone vs sirolimus monotherapy for kaposiform hemangioendothelioma: a randomized clinical trial – Blood (link to abstract – $ for full-text)

Hospital admissions from childhood common infections were largely reduced in England during the pandemic due to control measures for Covid-19.

17 Jan, 2022 | 00:37h | UTC

Indirect effects of the covid-19 pandemic on childhood infection in England: population based observational study – The BMJ

Editorial: Covid-19 control measures and common paediatric infections – The BMJ

News Release: Dramatic fall in hospital admissions for child infections during first year of covid-19 pandemic – BMJ

New UK Guidance: Self-isolation for those with COVID-19 can end after 5 full days following 2 negative rapid lateral flow tests – “The default self-isolation period continues to be 10 days, and you may only leave self-isolation early if you have taken 2 rapid lateral flow tests and do not have a temperature in line with guidance”.

14 Jan, 2022 | 08:48h | UTC

Self-isolation for those with COVID-19 can end after 5 full days following 2 negative LFD tests – Department of Health and Social Care

Commentary on Twitter (thread – click for more)

Self-isolation period for people infected with COVID in England will be reduced to 5 days from Monday 17 Jan. But it's conditional: 2 NEGATIVE tests on days 5 & 6, & no symptoms, & not in certain high risk situations e.g. working with vulnerable people
1/https://t.co/HLxlIbpbkR

— Andrew Lee is heading to @andrewleedr.bsky.social (@andrewleedr) January 13, 2022

In a study with 1110 children with prolonged fever, MRP8/14 serum levels were validated as a diagnostic marker for systemic juvenile idiopathic arthritis.

14 Jan, 2022 | 08:07h | UTC

MRP8/14 serum levels as diagnostic markers for systemic juvenile idiopathic arthritis in children with prolonged fever – Rheumatology (link to abstract – $ for full-text)

Commentary: It is about time: the first validated biomarker for early diagnosis of sJIA – Rheumatology

5 years later, researchers assess how children exposed to Zika are developing.

14 Jan, 2022 | 07:53h | UTC

5 years later, researchers assess how children exposed to Zika are developing – NPR

Observational study in adolescents showed the Pfizer-BioNTech vaccine had an overall effectiveness of 94% against hospitalization and 98% against critical Covid-19.

13 Jan, 2022 | 09:00h | UTC

Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents – New England Journal of Medicine

Editorial: Sparing of Severe Covid-19 in Vaccinated Adolescents – New England Journal of Medicine

The COVID generation: how is the pandemic affecting kids’ brains?

13 Jan, 2022 | 08:53h | UTC

The COVID generation: how is the pandemic affecting kids’ brains? – Nature

RCT: In full-term and near-term neonates, drug treatment of all clinically and electrographically detected seizures was not associated with reduced death rates or disability at 2 years compared with the treatment of only the clinically detected seizures.

13 Jan, 2022 | 08:24h | UTC

Effect of Treatment of Clinical Seizures vs Electrographic Seizures in Full-Term and Near-Term Neonates: A Randomized Clinical Trial – JAMA Network Open

Commentaries:

Should we treat electrographic seizures? – Neonatal Research

Subclinical Electrographic Seizures in the Newborn—Is More Treatment Better? – JAMA Network Open

Neonatal Seizures: Little Difference Between EEG/Clinical Treatment – Physician’s Weekly

Commentary on Twitter

NEST trial in @JAMANetworkOpen by @rodwhunt explores if treatment of EEG + clinical seizures compared with only treating clinical seizures in encephalopathic infants decreased odds of severe disability at 2 years of age. https://t.co/s3yYi6R3fV #EBNEOalerts #neoEBM #neotwitter pic.twitter.com/xoxVKC2a5z

— Evidence-Based Neo (@EBNEO) December 29, 2021