Pediatrics (all articles)
Hepatitis outbreak in children: explainer on adenovirus type 41, the possible culprit.
29 Apr, 2022 | 11:07h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
The Lancet Series: Optimizing child and adolescent health and development.
29 Apr, 2022 | 10:55h | UTCHomepage: Optimising Child and Adolescent Health and Development – The Lancet (free registration required for all articles)
Health and development from preconception to 20 years of age and human capital
Optimising child and adolescent health and development in the post-pandemic world
Opportunities in crisis for optimising child health and development
Tracing the emergence of drowning prevention on the global health and development agenda: a policy analysis.
29 Apr, 2022 | 08:16h | UTCRelated:
Prevention of Drowning – Pediatrics
Preventing drowning: an implementation guide – World Health Organization
Global report on drowning: preventing a leading killer – World Health Organization
Hidden Hazards: An Exploration of Open Water Drowning and Risks for Children – Safe Kids Worldwide
Commentary on Twitter
Authors of new @LancetGH article trace the emergence of #drowningprevention on global health & sustainable development agenda & highlight how first ever UN resolution can be a catalyst for action. https://t.co/ybiz4ckwCs pic.twitter.com/s48tIGefYG
— Etienne Krug (@etiennekrug) April 22, 2022
Cohort Study: Neurocognitive development in children at familial high risk of schizophrenia or bipolar disorder.
29 Apr, 2022 | 08:07h | UTCNeurocognitive Development in Children at Familial High Risk of Schizophrenia or Bipolar Disorder – JAMA Psychiatry (link to abstract – $ for full-text)
Commentary: Children at Risk for Schizophrenia Show Early Neurocognitive Deficits – Psychiatric News Alert
RCT: Nasal high-flow therapy during neonatal endotracheal intubation.
28 Apr, 2022 | 08:07h | UTCNasal High-Flow Therapy during Neonatal Endotracheal Intubation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Successful Intubations Up With Nasal High-Flow Therapy in Neonates – HealthDay
Commentary on Twitter
Nasal high-flow therapy during neonatal endotracheal intubation increased the likelihood of successful intubation on the first attempt without physiological instability. https://t.co/JWRgtAcoAN pic.twitter.com/EQdFW6pojF
— NEJM (@NEJM) April 27, 2022
Phase 2b trial: Prefusion F protein–based respiratory syncytial virus immunization in pregnancy.
28 Apr, 2022 | 08:09h | UTCPrefusion F Protein–Based Respiratory Syncytial Virus Immunization in Pregnancy – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: RSV Prefusion F Protein-Based Immunization Studied in Pregnancy – HealthDay
Commentary on Twitter
In pregnant women, RSVpreF vaccine elicited neutralizing antibody responses with efficient transplacental transfer and without evident safety concerns. https://t.co/r8oktZmBZQ pic.twitter.com/UE7ffxYJW6
— NEJM (@NEJM) April 27, 2022
Report: Investigation into acute hepatitis of unknown etiology in children in England.
27 Apr, 2022 | 08:08h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentary on Twitter
A comprehensive technical report is now available on the cases of hepatitis in young children
Leading hypothesis still Adenovirus, often only positive in blood
Of note, in cases where transplant was required virus levels were 12x higher than other caseshttps://t.co/VMk1qoIyNb
— Alasdair Munro (@apsmunro) April 26, 2022
RCT: Noninvasive high-frequency oscillatory ventilation vs. nasal continuous positive airway pressure vs. nasal intermittent positive pressure ventilation as postextubation support for preterm neonates.
27 Apr, 2022 | 07:59h | UTCNoninvasive High-Frequency Oscillatory Ventilation vs Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation as Postextubation Support for Preterm Neonates in China: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)
Commentaries on Twitter
In this randomized clinical trial, NHFOV and nasal intermittent positive pressure ventilation in neonates provided a small advantage of reduced need for invasive respiratory support when used from extubation and until discharge. https://t.co/qCtNP8Gwj9
— JAMA Pediatrics (@JAMAPediatrics) April 25, 2022
A RCT in @JAMAPediatrics evaluates total duration of mechanical ventilation, need for reintubation, and ventilator-free days after extubation to either NHFOV, NCPAP or NIPPV. https://t.co/krwwMv2Hbr#EBNEOalerts #neoEBM #neotwitter pic.twitter.com/uenwdlZfO4
— Evidence-Based Neo (@EBNEO) April 27, 2022
M-A: Efficacy and safety of laparoscopy for mild and moderate pediatric abdominal trauma.
27 Apr, 2022 | 07:39h | UTC
A therapeutic guide on pediatric irritable bowel syndrome and functional abdominal pain-not otherwise specified.
26 Apr, 2022 | 07:58h | UTC
Giant tube slides and broken legs: why the latest playground craze is a serious hazard.
26 Apr, 2022 | 07:50h | UTC
RCT: Effectiveness of cognitive behavioral therapy–based intervention in preventing gaming disorder and unspecified internet use disorder in adolescents.
26 Apr, 2022 | 07:42h | UTCCommentaries:
The Case for Prevention Research in Adolescent-Onset Mental Illness—Game On! – JAMA Network Open
Commentary on Twitter
This RCT of at-risk high school students showed that a short school-based prevention program can reduce gaming disorder and internet use disorder symptoms. https://t.co/L9VhwaRVDG pic.twitter.com/Ix8WzUBSSZ
— JAMA Network Open (@JAMANetworkOpen) February 18, 2022
WHO: Multi-country – acute, severe hepatitis of unknown origin in children.
25 Apr, 2022 | 01:13h | UTCMulti-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
Commentaries:
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
At least one child has died from mystery strain of severe hepatitis, WHO confirms – The Guardian
Related:
CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention AND Guidance: Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Review: The brain in pediatric critical care: unique aspects of assessment, monitoring, investigations, and follow-up.
25 Apr, 2022 | 00:26h | UTC
Commentary on Twitter
The brain in #PICU
🧠vulnerable brains
🧠(age-appropriate) tools to assess neuro-function
🧠latest evidence related to neurocritical care monitoring in #PedsICU
🧠post discharge: PICS‑p & approaches for neurodevelopmental follow‑up #FOAMcc #FOAMped
📎 https://t.co/F8c1L7ysPy pic.twitter.com/zsXe3Tv5ns— Intensive Care Medicine (@yourICM) April 22, 2022
CDC alerts providers to hepatitis cases of unknown origin.
22 Apr, 2022 | 09:34h | UTCCommentaries:
CDC issues health advisory about acute hepatitis in children – CNN
CDC Issues Alert for Hepatitis in Children With Adenovirus Infection – WebMD
Related:
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
UK drug regulator advises patients and doctors against the use of Pregabalin during pregnancy due to a possible increased risk of congenital malformations.
22 Apr, 2022 | 09:31h | UTCSee also: Pregabalin and risks in pregnancy – Medicines and Healthcare products Regulatory Agency
Source: Avoid prescribing pregabalin during pregnancy if possible, says UK drug regulator – The BMJ ($)
Commentary on Twitter
The Medicines and Healthcare Products Regulatory Agency (@MHRAgovuk) has strengthened its warning about avoiding pregabalin during pregnancy after new data showed an increased risk of major congenital malformations associated with the drug https://t.co/ghGvqCqA0C
— The BMJ (@bmj_latest) April 22, 2022
Studies highlight meningitis vaccine’s potential against gonorrhea.
20 Apr, 2022 | 10:06h | UTCCommentary: Studies highlight meningitis vaccine’s potential against gonorrhea – CIDRAP
News Release: Threat of untreatable gonorrhoea could be tackled using an existing meningitis vaccine – The Lancet
Study 1: Effectiveness of a serogroup B outer membrane vesicle meningococcal vaccine against gonorrhoea: a retrospective observational study – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Study 2: Effectiveness and impact of the 4CMenB vaccine against invasive serogroup B meningococcal disease and gonorrhoea in an infant, child, and adolescent programme: an observational cohort and case-control study – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Cohort Study: Rates and causes of mortality among children and young people with and without intellectual disabilities in Scotland.
20 Apr, 2022 | 09:22h | UTC
Commentary on Twitter
Very sobering study based on Scottish data. Children and young people with intellectual disability are at far higher risk of death and are more likely to have an avoidable death – one amenable to timely, effective care. https://t.co/xuxYjVrRd8
— Mary Dixon-Woods (@MaryDixonWoods) April 16, 2022
National, regional, and global estimates of anemia by severity in women and children for 2000–19.
20 Apr, 2022 | 09:25h | UTCInvited Commentary: Sustainable Development Goals for anaemia: 20 years later, where are we now? – The Lancet Global Health
Cohort Study: Association of maternal autoimmune diseases with risk of mental disorders in offspring in Denmark.
20 Apr, 2022 | 09:19h | UTC
Commentary on Twitter
https://twitter.com/JAMANetworkOpen/status/1515057370715594753
M-A: Invasive group A streptococcal disease in pregnant women and young children.
20 Apr, 2022 | 09:05h | UTCInvited Commentary: Recognising group A streptococcal disease in pregnancy – The Lancet Infectious Diseases (free registration required)
Systematic Review: Continuous positive airway pressure (CPAP) for acute bronchiolitis in children.
20 Apr, 2022 | 09:02h | UTCContinuous positive airway pressure (CPAP) for acute bronchiolitis in children – Cochrane Library
Summary: Continuous positive airway pressure (CPAP) for acute bronchiolitis in children – Cochrane Library
Systematic Review: Repeat doses of prenatal corticosteroids for women at risk of preterm birth for improving neonatal health outcomes.
20 Apr, 2022 | 09:03h | UTC
Cohort Study: Association of treatment with antipsychotics, antidepressants, or both with movement disorders and seizures among children and adolescents with depression.
19 Apr, 2022 | 01:50h | UTC
Commentary on Twitter
In this cohort study, adjunctive antipsychotics with antidepressants were associated with movement disorders and seizures compared with antidepressant monotherapy in children and adolescents with depression. https://t.co/3SVKEThwkR
— JAMA Network Open (@JAMANetworkOpen) April 15, 2022
Analysis of an intervention for emergency medical services personnel to reduce epinephrine dosing errors in infants.
19 Apr, 2022 | 01:52h | UTC
Commentary on Twitter
In this QI study, an infant resuscitation simulation intervention using 1mL syringes to draw up epinephrine (vs dosing from prefilled 10mL syringes) was associated with increased appropriate epinephrine use & fewer dosage errors, in less time. https://t.co/M3ztB1LMDi
— JAMA Network Open (@JAMANetworkOpen) April 15, 2022