Pediatrics (all articles)

Antibiotic Therapy versus Appendectomy for Acute Uncomplicated Appendicitis

29 Mar, 2017 | 17:05h | UTC

Comparison of Antibiotic Therapy and Appendectomy for Acute Uncomplicated Appendicitis in Children: A Meta-analysis – JAMA Pediatrics(free)

Editorial: Medical Treatment of Pediatric Appendicitis: Are We There Yet? (free)

See also a recent meta-analysis and related commentaries on the same subject (free)

Nonoperative treatment was successful in 90% of cases. Subgroup analysis indicated an increased risk for initial fails and recurrent appendicitis in those with appendicolith.

 

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Screening for Celiac Disease

29 Mar, 2017 | 17:04h | UTC

Screening for Celiac Disease: US Preventive Services Task Force Recommendation Statement (free)

Editorial 1: The US Preventive Services Task Force Recommendation on Screening for Asymptomatic Celiac Disease: A Dearth of Evidence (free)

Editorial 2: Celiac Disease and Nonceliac Gluten or Wheat Sensitivity: The Risks and Benefits of Diagnosis (free)

“Some sanity about screening for asymptomatic celiac disease in the gluten-free diet “epidemic” era” (RT @EricTopol see Tweet)

 

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Prenatal nutrition, socioenvironmental conditions, and child development

27 Mar, 2017 | 00:43h | UTC

Maternal multiple micronutrient supplementation and other biomedical and socioenvironmental influences on children’s cognition at age 9–12 years in Indonesia: follow-up of the SUMMIT randomised trial – The Lancet Global Health (free)

Related commentary: Prenatal nutrition, socioenvironmental conditions, and child development (free)

“Maternal MMN had long-term benefits for child cognitive development at 9–12 years of age, thereby supporting its role in early childhood development, and policy change toward MMN”. The related commentary above does not seem to agree with this statement from the authors, stating that the new evidence does not provide enough weight for a policy change from prenatal iron and folate to MMN supplementation.

 

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Efficacy of Heat-Stable Oral Rotavirus Vaccine

23 Mar, 2017 | 17:18h | UTC

Efficacy of a Low-Cost, Heat-Stable Oral Rotavirus Vaccine in Niger – New England Journal of Medicine (free)

Editorial: Rotavirus Vaccines – A New Hope (free)

Quick Take Video Summary: Efficacy of Heat-Stable Oral Rotavirus Vaccine (free)

 

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