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Oncology (all articles)

Current Diagnosis and Management of Small-Cell Lung Cancer

28 Aug, 2019 | 02:04h | UTC

Current Diagnosis and Management of Small-Cell Lung Cancer – Mayo Clinic Proceedings (free)

 


Non–Small Cell Lung Cancer: Epidemiology, Screening, Diagnosis, and Treatment

28 Aug, 2019 | 02:05h | UTC

Non–Small Cell Lung Cancer: Epidemiology, Screening, Diagnosis, and Treatment – Mayo Clinic Proceedings (free)

 


Position Statement: Safe Use of Immune Checkpoint Inhibitors in the Multidisciplinary Management of Urological Cancer

27 Aug, 2019 | 00:25h | UTC

Safe Use of Immune Checkpoint Inhibitors in the Multidisciplinary Management of Urological Cancer: The European Association of Urology Position in 2019 – European Urology (free)

Related: Immune Checkpoint Inhibitor Toxicities (free guidelines and reviews on the subject)

 


Meta-Analysis: Preoperative Physical Exercise Interventions in Patients with Non-Small-Cell Lung Cancer

27 Aug, 2019 | 00:15h | UTC

Systematic Review and Meta-Analysis of Randomized, Controlled Trials on Preoperative Physical Exercise Interventions in Patients with Non-Small-Cell Lung Cancer – Cancers (free)

Related: Preoperative exercise training for patients with non‐small cell lung cancer – Cochrane Library (free) AND Preoperative patient preparation in enhanced recovery pathways – Journal of Anaesthesiology Clinical Pharmacology (free)

 


Randomized Trial: Neoadjuvant Radiotherapy for Resectable Hepatocellular Carcinoma With Portal Vein Tumor Thrombus

27 Aug, 2019 | 00:09h | UTC

Neoadjuvant Three-Dimensional Conformal Radiotherapy for Resectable Hepatocellular Carcinoma With Portal Vein Tumor Thrombus: A Randomized, Open-Label, Multicenter Controlled Study – Journal of Clinical Oncology (free)

Commentary: Neoadjuvant Radiotherapy vs Surgery Alone for Resectable Hepatocellular Carcinoma With Tumor Thrombus – The ASCO Post (free)

Source: EvidenceAlerts

 


CDC: 92% of Human Papillomavirus–Attributable Cancers can be Targeted by HPV Vaccination

25 Aug, 2019 | 21:14h | UTC

Human Papillomavirus–Attributable Cancers — United States, 2012–2016 – Centers for Disease Control and Prevention (free)

Commentary: Most HPV-linked cancers due to types targeted by 9vHPV vaccine – MedicalXpress (free)

Related: CDC Updates Recommendations for Human Papillomavirus Vaccination for Adults (free)

 


Brachytherapy: An Overview for Clinicians

25 Aug, 2019 | 21:09h | UTC

Brachytherapy: An overview for clinicians – CA: A Cancer Journal for Clinicians (free)

 


Review: Influence of Perioperative Anesthetic and Analgesic Interventions on Oncological Outcomes

25 Aug, 2019 | 13:47h | UTC

Influence of perioperative anaesthetic and analgesic interventions on oncological outcomes: a narrative review – British Journal of Anaesthesia (free)

 


[Abstract Only] Study: Metastatic Esophageal Cancer Lymph Node Response to Neoadjuvant Chemotherapy May Predict Long-term Survival More Precisely than the Primary Tumor Response

25 Aug, 2019 | 13:47h | UTC

Lymph Node Response to Neoadjuvant Chemotherapy as an Independent Prognostic Factor in Metastatic Esophageal Cancer – Annals of Surgery (link to abstract – $ for full-text)

Commentaries: Can Lymph Node Response to Neoadjuvant Chemotherapy Predict Prognosis in Esophageal Cancer? – The ASCO Post (free) AND Lymph nodes can predict survival in patients with esophageal cancer – Osaka University (free)

 


Review: Development of Exercise as Interception Therapy for Cancer

23 Aug, 2019 | 08:42h | UTC

Development of Exercise as Interception Therapy for Cancer: A Review – JAMA Oncology (free for a limited period)

Related: Clinical Oncology Society of Australia position statement on exercise in cancer care – The Medical Journal of Australia (free PDF) AND The Exercise and Sports Science Australia position statement: Exercise medicine in cancer management – Journal of Science and Medicine in Sport (free)

 


Study: Risks of Specific Cardiovascular Diseases in Survivors of 20 Adult Cancers

22 Aug, 2019 | 11:03h | UTC

Medium and long-term risks of specific cardiovascular diseases in survivors of 20 adult cancers: a population-based cohort study using multiple linked UK electronic health records databases – The Lancet (free)

Commentaries: Is it time to include cancer in cardiovascular risk prediction tools? – The Lancet (free) AND Cancer survivors likely to face increase in long-term risk of cardiovascular disease – London School of Hygiene and Tropical Medicine (free)

Related: AHA Statement: Cardio-Oncology Rehabilitation to Manage Cardiovascular Outcomes in Cancer Patients and Survivors (free guidelines) AND Practical Integration of the ASCO Guidelines for Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers (free guidelines)

 


Observational Study: Antibiotics Exposure Linked to Higher Risk of Colorectal Cancer

22 Aug, 2019 | 10:52h | UTC

Oral antibiotic use and risk of colorectal cancer in the United Kingdom, 1989–2012: a matched case–control study – Gut (free)

Commentaries: Antibiotic use linked to heightened bowel cancer risk – BMJ (free) AND Antibiotics and bowel cancer: Study finds link – Medical News Today (free) AND Oral antibiotic use linked to heightened bowel cancer risk – OnMedica (free)

 


USPSTF Statement on BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing

21 Aug, 2019 | 08:42h | UTC

BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing – US Preventive Services Task Force (free)

Editorials: Broadening Criteria for BRCA1/2 Evaluation: Placing the USPSTF Recommendation in Context – JAMA (free for a limited period) AND Hereditary Cancer Evaluation in 2019—a Rapidly Evolving Landscape – JAMA Oncology (free for a limited period) AND US Preventive Services Task Force Breast Cancer Recommendation Statement on Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer – JAMA Surgery (free for a limited period) AND USPSTF Recommendations for BRCA1 and BRCA2Testing in the Context of a Transformative National Cancer Control Plan – JAMA Network Open (free)

Author Interview: USPSTF Recommendation: Assessment, Counseling, and Testing for BRCA-Related Cancer (free audio)

Commentaries: More women should be assessed for BRCA mutations, new recommendations say – CNN (free) AND Expert panel updates advice on BRCA cancer gene screening – Reuters (free)

 


Precision Medicine in Breast Cancer: Scientists Have used Artificial Intelligence to Identified Gene Sequences and Molecular Data Patterns that May Predict Response to Different Treatments

18 Aug, 2019 | 21:39h | UTC

Heterocellular gene signatures reveal luminal-A breast cancer heterogeneity and differential therapeutic responses – npj Breast Cancer (free)

Commentary: AI reveals new breast cancer types that respond differently to treatment – Institute of Cancer Research (free)

 


Consensus: Oligometastatic Prostate Cancer

18 Aug, 2019 | 21:42h | UTC

Oligometastatic Prostate Cancer: Results of a Dutch Multidisciplinary Consensus Meeting – European Urology Oncology (free)

Related Guideline: NICE Guideline: Diagnosis and Management of Prostate Cancer (free)

 


ASCO Guideline Update: Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women with Early-Stage Invasive Breast Cancer

18 Aug, 2019 | 21:32h | UTC

Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: ASCO Clinical Practice Guideline Update—Integration of Results From TAILORx – Journal of Clinical Oncology (free)

Related Research: ASCO 2018: Many Women with Early-Stage Breast Cancer Can Forgo Chemotherapy When Guided by a 21-Gene Expression Assay (free study and commentaries)

 


NCCN Guidelines Insights: Ovarian Cancer

18 Aug, 2019 | 21:30h | UTC

NCCN Guidelines Insights: Ovarian Cancer, Version 1.2019 – Journal of the National Comprehensive Cancer Network (free)

 


U.S. Cancer Statistics for Adults Aged 85 Years and Older

18 Aug, 2019 | 21:26h | UTC

Cancer statistics for adults aged 85 years and older, 2019 – CA: A Cancer Journal for Clinicians (free)

Commentary: Cancer in Adults Aged 85 and Older: Rates, Screening, and Survival – The ASCO Post (free)

 

Related Commentary on Twitter

 


Review: The Use of MRI and PET Imaging Studies for Prostate Cancer Management

18 Aug, 2019 | 21:11h | UTC

The Use of MRI and PET Imaging Studies for Prostate Cancer Management: Brief Update, Clinical Recommendations, and Technological Limitations – Medical Sciences (free)

 


Communication Strategies for Sharing Prognostic Information with Patients: Beyond Survival Statistics

16 Aug, 2019 | 08:05h | UTC

Communication Strategies for Sharing Prognostic Information With Patients: Beyond Survival Statistics – JAMA (free for a limited period)

See also: Author Interview (free audio)

 


[Abstract Only] Cohort Study: Individuals with 1 or 2 Small Adenomas at Baseline Screening Colonoscopy Have a Similar Risk of Advanced Neoplasia over 10 years as Individuals with no Baseline Adenomas

14 Aug, 2019 | 08:34h | UTC

Baseline Colonoscopy Findings Associated with 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance – Gastroenterology (link to abstract – $ for full-text)

Related Study: Colonoscopy Adenoma Findings and Long-term Colorectal Cancer Incidence (free study, commentaries and guidelines on the subject)

Source: NEJM Journal Watch ($)

 


‘War on Cancer’ Metaphors May do Harm, Research Shows

13 Aug, 2019 | 05:28h | UTC

‘War on cancer’ metaphors may do harm, research shows – The Guardian (free)

Related: Why cancer is not a war, fight, or battle – CNN (free) AND He’s a Fighter – The Atlantic (free) AND Cancer cliches to avoid: I’m not ‘brave’ – BBC (free)

 


Review: Management of Ovarian Cancer Risk in Women with BRCA1/2 pathogenic variants

13 Aug, 2019 | 05:23h | UTC

Management of ovarian cancer risk in women with BRCA1/2 pathogenic variants – Canadian Medical Association Journal (free for a limited period)

Commentaries: Review Offers Guidance on Managing Ovarian Cancer Risk in BRCA Mutation Carriers – NEJM Journal Watch (free) AND Managing ovarian cancer risk in women with BRCA1/2 genetic variants – Joule Inc. (free)

Related: USPSTF Draft Statement: BRCA-Related Cancer Risk Assessment, Genetic Counseling, and Genetic Testing (free draft statement and commentaries) AND Prevention and screening in BRCA mutation carriers and other breast/ovarian hereditary cancer syndromes: ESMO Clinical Practice Guidelines for cancer prevention and screening (free) AND Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers (free study and commentaries)

 


Study: Androgen-deprivation Therapies May Increase the Risk of QT Prolongation and Arrhythmias

13 Aug, 2019 | 01:26h | UTC

Androgenic Effects on Ventricular Repolarization: A Translational Study From the International Pharmacovigilance Database to iPSC-Cardiomyocytes – Circulation (free PDF for a limited period)

Commentaries: Androgen-Deprivation Therapy May Increase Risk for QT Prolongation and Torsades de Pointes – The ASCO Post (free) AND ADT Linked to Arrhythmias, QT Prolongation – MedPage Today (free registration required)

 


Meta-Analysis: Lobectomy vs. Segmentectomy in Stage I Non-Small Cell Lung Cancer

13 Aug, 2019 | 01:07h | UTC

A Meta-Analysis Comparing Lobectomy versus Segmentectomy in Stage I Non-Small Cell Lung Cancer – The Korean Journal of Thoracic and Cardiovascular Surgery (free)

 


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