Oncology (all articles)
Critical Care Management of Toxicities Associated with Targeted Agents and Immunotherapies for Cancer
7 Jan, 2020 | 01:45h | UTCRelated: Immune Checkpoint Inhibitor Toxicities (free guidelines and reviews on the subject)
Meta-analysis of Observational Studies: Use of Antibiotics Linked to Poor Outcomes in Patients Receiving Immune-checkpoint Blockade
6 Jan, 2020 | 23:24h | UTCRelated: Observational Study Suggests Antibiotics Can Greatly Impair the Response to Immune Checkpoint Inhibitors in Patients with Cancer – JAMA Oncology (link to abstract and commentaries)
Systematic Review: Immunotherapy in Pediatric Solid Tumors
6 Jan, 2020 | 23:11h | UTCImmunotherapy in Pediatric Solid Tumors—A Systematic Review – Cancers (free)
Study: Google Artificial Intelligence Algorithm Improves Accuracy of Breast Cancer Detection in Mammography
5 Jan, 2020 | 14:14h | UTCInternational evaluation of an AI system for breast cancer screening – Nature (free link via STAT)
Commentaries: AI shows promise for breast cancer screening – Nature (free) AND Google AI tool can pinpoint breast cancer better than clinicians, new study suggests – STAT (free) AND Artificial intelligence could help to spot breast cancer – Imperial College London (free) AND AI can now outperform doctors at detecting breast cancer. Here’s why it won’t replace them – Vox (free) AND A.I. Is Learning to Read Mammograms – The New York Times (10 articles per month are free) AND Study finds Google system could improve breast cancer detection – Reuters (free)
[Abstract Only] Observational Study: Taking Supplements During Chemotherapy Linked to Increased Risk of Disease Recurrence and Death
5 Jan, 2020 | 13:34h | UTCDietary Supplement Use During Chemotherapy and Survival Outcomes of Patients With Breast Cancer Enrolled in a Cooperative Group Clinical Trial (SWOG S0221) – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentaries: Antioxidant use during chemotherapy risky for breast cancer patients- SWOG (free) AND Taking certain vitamins during breast cancer chemo tied to recurrence, death – Reuters (free) AND Dietary supplement use during chemotherapy and survival outcomes of patients with breast cancer enrolled in a cooperative group clinical trial – 2 Minute Medicine (free)
Alcohol and Cancer Risk: Clinical and Research Implications
5 Jan, 2020 | 13:23h | UTCAlcohol and Cancer Risk: Clinical and Research Implications – JAMA (free for a limited period)
Related: Study: Even Light Alcohol Consumption Linked to Increased Cancer Risk (studies on the subject)
Meta-Analysis: Acupuncture may Reduce Pain Intensity in Patients with Cancer
5 Jan, 2020 | 13:19h | UTCCommentaries: Acupunture may help reduce cancer pain, analysis finds – UPI (free) AND Acupuncture, acupressure may help cancer patients control pain – MedicalXpress (free)
[Abstract Only] Randomized Trial: Accelerated Partial Breast Irradiation vs. Whole-breast Irradiation After Breast-conserving Surgery for Early-stage Breast Cancer
5 Jan, 2020 | 13:05h | UTCLong-term primary results of accelerated partial breast irradiation after breast-conserving surgery for early-stage breast cancer: a randomised, phase 3, equivalence trial – The Lancet (link to abstract – $ for full-text)
Related Commentary on Twitter
PRESS RELEASE: Accelerated Partial Breast Irradiation Although Close was Not Equivalent to Whole-breast Irradiation to Control Ipsilateral Breast Tumor Recurrence https://t.co/mCvuC5aeag #breastcancer pic.twitter.com/KRXAAtAjbj
— NRG Oncology (@NRGonc) December 6, 2019
[Abstract Only] Randomized Trial: External Beam Accelerated Partial Breast Irradiation vs. Whole Breast Irradiation after Breast Conserving Surgery in Women with Ductal Carcinoma in Situ and Node-negative Breast Cancer
5 Jan, 2020 | 13:08h | UTCExternal beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in women with ductal carcinoma in situ and node-negative breast cancer (RAPID): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentary: Results mixed for twice-daily APBI in early breast cancer – MedicalXpress (free)
Related Commentary on Twitter
NEW: External beam accelerated partial breast irradiation was non-inferior to whole breast irradiation in preventing ipsilateral breast tumour recurrence: finding from the RAPID randomised controlled trial https://t.co/4aexxXC8Vg pic.twitter.com/JMa0jUWY1X
— The Lancet (@TheLancet) December 6, 2019
Hypertension in Cancer Patients and Survivors: Epidemiology, Diagnosis, and Management
5 Jan, 2020 | 12:59h | UTC
AGA Clinical Practice Guidelines on Management of Gastric Intestinal Metaplasia
13 Dec, 2019 | 10:23h | UTCAGA Clinical Practice Guidelines on Management of Gastric Intestinal Metaplasia – Gastroenterology (free PDF)
News Release: AGA releases guideline on management of gastric intestinal metaplasia – American Gastroenterological Association (free)
Study: Even Light Alcohol Consumption Linked to Increased Cancer Risk
10 Dec, 2019 | 08:28h | UTCLight to moderate amount of lifetime alcohol consumption and risk of cancer in Japan – Cancer (free)
Commentaries: Even light alcohol consumption linked to higher cancer risk in Japan – Wiley (free)
Related: Alcohol and Cancer: A Statement of the American Society of Clinical Oncology (free Statement and commentaries) AND Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies – The Lancet (free study and commentaries)
Randomized Trial: Effect of Thoracoscopic Talc Poudrage vs. Talc Slurry via Chest Tube on Pleurodesis Failure Rate Among Patients With Malignant Pleural Effusions
6 Dec, 2019 | 10:21h | UTCEffect of Thoracoscopic Talc Poudrage vs Talc Slurry via Chest Tube on Pleurodesis Failure Rate Among Patients With Malignant Pleural Effusions: A Randomized Clinical Trial – JAMA (free for a limited period)
Related Commentary on Twitter
Among patients with malignant pleural effusion, there was no significant difference in the rate of pleurodesis failure between the use of talc poudrage and talc slurry https://t.co/AxWOdzvEnA
— JAMA (@JAMA_current) December 6, 2019
[Abstract Only] Cohort Study: Hair Dye and Chemical Straightener Associated with Increased Risk of Breast Cancer
5 Dec, 2019 | 07:49h | UTCHair dye and chemical straightener use and breast cancer risk in a large US population of black and white women – International Journal of Cancer (link to abstract – $ for full-text)
Commentaries: Permanent hair dye and straighteners may increase breast cancer risk – NIH News Releases (free) AND Hair Dyes And Straighteners Linked To Higher Cancer Risk, Especially For Black Women – NPR (free)
Guideline: Post-polypectomy and Post-colorectal Cancer Resection Surveillance
4 Dec, 2019 | 08:30h | UTCRelated Studies: Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence – JAMA (free) AND Long-term Risk of Colorectal Cancer and Related Death After Adenoma Removal in a Large, Community-based Population – Gastroenterology (link to abstract – $ for full-text) AND Baseline Colonoscopy Findings Associated with 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance – Gastroenterology (link to abstract – $ for full-text)
Related Reviews: Optimizing post‐polypectomy surveillance: A practical guide for the endoscopist – Digestive Endoscopy (free) AND Optimal Colonoscopy Surveillance Interval after Polypectomy – Clinical Endoscopy (free)
Related Guidelines: Endoscopic surveillance after surgical or endoscopic resection for colorectal cancer: European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Digestive Oncology (ESDO) Guideline – Endoscopy (free) AND Guidelines for Colonoscopy Surveillance After Screening and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer (free) AND Korean Guidelines for Postpolypectomy Colonoscopy Surveillance – Digestive Endoscopy (free) AND Colorectal cancer surveillance after index colonoscopy: Guidance from the Canadian Association of Gastroenterology (free) AND Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) Guideline (free)
Guidelines for the Management of Hereditary Colorectal Cancer
4 Dec, 2019 | 08:28h | UTCRelated Guidelines: Clinical Practice Guideline on Screening for Colorectal Cancer in Individuals With a Family History of Nonhereditary Colorectal Cancer or Adenoma: The Canadian Association of Gastroenterology Banff Consensus – Gastroenterology (free) AND Endoscopic management of Lynch syndrome and of familial risk of colorectal cancer: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Endoscopy (free)
Randomized Trial: Single-Fraction vs. Multifraction Radiotherapy for Spinal Canal Compression from Metastatic Cancer
4 Dec, 2019 | 08:18h | UTCEffect of Single-Fraction vs Multifraction Radiotherapy on Ambulatory Status Among Patients With Spinal Canal Compression From Metastatic Cancer: The SCORAD Randomized Clinical Trial – JAMA (free for a limited period)
Commentary: One dose of radiotherapy as effective as five doses for cancer in the spine – University College London (free)
Randomized Trial: Synchronous vs. Sequential Chemo-radiotherapy in Patients with Early Stage Breast Cancer
4 Dec, 2019 | 08:17h | UTC
Artificial Intelligence in Digital Pathology — New Tools for Diagnosis and Precision Oncology
1 Dec, 2019 | 22:03h | UTC
Meta-analysis: Association Between Marijuana Use and Risk of Cancer
1 Dec, 2019 | 21:50h | UTCCommentary: No Link Between Marijuana Use and Cancer, Except TGCT – Medscape (free registration required)
Guidelines on Topical Photodynamic Therapy: Treatment Delivery and Established Indications
1 Dec, 2019 | 21:49h | UTCRelated: British Association of Dermatologists and British Photodermatology Group guidelines for topical photodynamic therapy 2018 – British Journal of Dermatology (free) AND Photodynamic Therapy: A Clinical Consensus Guide – Dermatologic Surgery (free)
Ten-year Outcomes in Men with Localized Prostate Cancer from the ProtecT Randomized Controlled Trial According to Treatment Received
29 Nov, 2019 | 08:24h | UTCOriginal Study: 10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer – New England Journal of Medicine (free)
Related Commentary on Twitter
Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatment Received@Freddie_Hamdy @JimCatto https://t.co/sNfevwU3R4 pic.twitter.com/uqnoZUgSRm
— European Urology (@EUplatinum) November 25, 2019
[Abstract Only] Randomized Trial: Supplemental MRI Screening vs. Usual Care with Mammography Only for Women with Extremely Dense Breast Tissue
28 Nov, 2019 | 10:39h | UTCSupplemental MRI Screening for Women with Extremely Dense Breast Tissue – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Does MRI Screening Benefit Women With Extremely Dense Breasts? – U.S. News (free) AND Mixed Results With Mammo Plus MRI Screening – MedPage Today (free)
“The benefits need to be carefully weighed against the harms, as MRI examination is more expensive, and it requires the injection of a contrast agent into the body. MRI will also detect abnormalities that later turn out not to be breast cancer after all” (from U.S News)
Related Commentary on Twitter
In this randomized trial, women with extremely dense breast tissue were invited to undergo MRI screening or received only mammography during a 2-year screening period. https://t.co/tZmcappO00
— NEJM (@NEJM) November 27, 2019
Breast Cancer Screening and Diagnosis: A Synopsis of the European Breast Guidelines
27 Nov, 2019 | 08:19h | UTCCommentary: European guidelines for breast cancer screening differ from U.S. recommendations – ACP Internist (free)
Related: ACP Guideline: Screening for Breast Cancer in Average-Risk Women (other guidelines and commentaries on the subject)
Systematic Review: Follow‐up Strategies Following Completion of Primary Cancer Treatment in Adult Cancer Survivors
27 Nov, 2019 | 07:54h | UTCFollow‐up strategies following completion of primary cancer treatment in adult cancer survivors – Cochrane Library (free)
Summary: Follow-up strategies after completion of primary cancer treatment – Cochrane Library (free)