Oncology (all articles)
Estimating the Magnitude of Cancer Overdiagnosis in Australia
28 Jan, 2020 | 08:59h | UTCEstimating the magnitude of cancer overdiagnosis in Australia – Medical Journal of Australia (free)
Commentary: 29,000 cancers overdiagnosed in Australia in a single year – The Conversation (free)
Related: Overdiagnosis: what it is and what it isn’t – BMJ Evidence Based Medicine (free) AND Overdiagnosis across medical disciplines: a scoping review – The BMJ Open (free) AND Too much medical care: bad for you, bad for health care systems – STAT News (free) AND Position Paper on Overdiagnosis and Action to be Taken – Wonca (free PDF) AND Screening: How overdiagnosis and other harms can undermine the benefits – Health News Review (free) AND Overdiagnosis: causes and consequences in primary health care – Canadian Family Physician (free) AND Five warning signs of overdiagnosis – The Conversation (free) AND What is overdiagnosed cancer? And why does it matter? – Croakey (free) AND Blame rising cancer overdiagnosis on ‘irrational exuberance’ for early detection – STAT (free) AND Preventing overdiagnosis and the harms of too much sport and exercise medicine – British Journal of Sports Medicine (free)
Reverse Cardio‐Oncology: Cancer Development in Patients With Cardiovascular Disease
28 Jan, 2020 | 08:53h | UTC
Studies: Whole-body MRI Compared with Standard Pathways for Staging Metastatic Disease in Lung and Colorectal Cancer
26 Jan, 2020 | 22:44h | UTCOriginal Studies: Whole body MRI for Colorectal and Lung Cancer Staging (free studies and commentaries)
Source: EvidenceAlerts
“In colorectal and non-small-cell lung cancer, the whole-body magnetic resonance imaging staging pathway has similar accuracy to standard staging pathways, is generally preferred by patients, improves staging efficiency and has lower staging costs.”
ASCO Guideline: Molecular Biomarkers in Localized Prostate Cancer
23 Jan, 2020 | 02:00h | UTCMolecular Biomarkers in Localized Prostate Cancer: ASCO Guideline – Journal of Clinical Oncology (free)
ASCO Guideline: Lung Cancer Surveillance After Definitive Curative-Intent Therapy
23 Jan, 2020 | 02:01h | UTC
[Abstract Only] Randomized Trial: Cabazitaxel vs. Abiraterone or Enzalutamide in Metastatic Prostate Cancer
23 Jan, 2020 | 01:48h | UTCCabazitaxel versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: ESMO 2019: Cabazitaxel vs Abiraterone or Enzalutamide in Previously Treated Metastatic Castration-Resistant Prostate Cancer – The ASCO Post (free)
Related Commentary on Twitter
#VisualAbstract: Cabazitaxel in Metastatic Prostate Cancer. See more NEJM Visual Abstracts now: pic.twitter.com/nUeb6dqRYi
— NEJM (@NEJM) December 26, 2019
Opinion: Our Best Weapons Against Cancer are Not Magic Bullets
22 Jan, 2020 | 09:23h | UTCOur best weapons against cancer are not magic bullets – Nature (free)
Immune Checkpoint Inhibitor Myocarditis: Pathophysiological Characteristics, Diagnosis, and Treatment
22 Jan, 2020 | 09:15h | UTCRelated: Cardiotoxicity of immune checkpoint inhibitors – ESMO Open (free) AND Cardiotoxicity from immune checkpoint inhibitors – IJC Heart & Vasculature (free) AND Cardiovascular toxicity of immune checkpoint inhibitors in cancer patients: A review when cardiology meets immuno-oncology – Journal of the Formosan Medical Association (free) AND Immune-Checkpoint Inhibitor-Induced Fulminant Myocarditis and Cardiogenic Shock – JACC: CardioOncology (free)
[Abstract Only] Randomized Trial: Effects of Addition of Anti-thymocyte Globulin to Standard Graft-versus-host Disease Prophylaxis in Patients with Hematological Malignancies Undergoing Transplantation from Unrelated Donor
22 Jan, 2020 | 09:16h | UTCAddition of anti-thymocyte globulin to standard graft-versus-host disease prophylaxis versus standard treatment alone in patients with haematological malignancies undergoing transplantation from unrelated donors: final analysis of a randomised, open-label, multicentre, phase 3 trial – The Lancet Haematology (link to abstract – $ for full-text)
Palliative Sedation: A Safety Net for the Relief of Refractory and Intolerable Symptoms at the End of Life
22 Jan, 2020 | 09:06h | UTC
ASTRO Guideline: Definitive and Postoperative Radiation Therapy for Basal and Squamous Cell Cancers of the Skin
21 Jan, 2020 | 01:35h | UTCCommentary: ASTRO Issues Clinical Guideline on Radiation Therapy for Basal Cell and Cutaneous Squamous Cell Carcinomas – The ASCO Post (free)
Onco-cardiology: Drug-drug Interactions of Antineoplastic and Cardiovascular Drugs
21 Jan, 2020 | 01:27h | UTC
A Review of Cancer Immunotherapy Toxicity
19 Jan, 2020 | 21:38h | UTCA review of cancer immunotherapy toxicity – CA: A Cancer Journal for Clinicians (free)
Related: Immune Checkpoint Inhibitor Toxicities (free guidelines and reviews on the subject)
3-year Follow-up of the SCOT RCT: 3-month Oxaliplatin-containing Adjuvant Chemotherapy is Non-inferior to 6 Months of the Same Regimen for Patients with High-risk Stage II and III Colorectal Cancer
19 Jan, 2020 | 21:28h | UTCOriginal Article: 3 versus 6 months of adjuvant oxaliplatin-fluoropyrimidine combination therapy for colorectal cancer (SCOT): an international, randomised, phase 3, non-inferiority trial – The Lancet Oncology (free)
Source: EvidenceAlerts
[Abstract Only] Randomized Trial: Different Doses of Adjuvant Ipilimumab vs. High-Dose Interferon Alfa-2b in Patients with Resected High-Risk Melanoma
19 Jan, 2020 | 20:40h | UTCOriginal Study: Phase III Study of Adjuvant Ipilimumab (3 or 10 mg/kg) Versus High-Dose Interferon Alfa-2b for Resected High-Risk Melanoma: North American Intergroup E1609 – Journal of Clinical Oncology (link to abstract – $ for full-text)
Randomized Trial: Effect of Dasatinib vs. Imatinib in the Treatment of Pediatric Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia
19 Jan, 2020 | 20:38h | UTCEffect of Dasatinib vs Imatinib in the Treatment of Pediatric Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA Oncology (free for a limited period)
Commentary: Dasatinib Superior to Imatinib in Pediatric ALL – MedPage Today (free)
Cohort Study: Association of Baseline Prostate-Specific Antigen Level with Long-term Diagnosis of Clinically Significant Prostate Cancer Among Patients Aged 55 to 60 Years
17 Jan, 2020 | 09:31h | UTCCommentary: PSA repeat screening strategy should be tailored to baseline PSA – MedwireNews (free)
ASCO Guideline: Optimum Imaging Strategies for Advanced Prostate Cancer
17 Jan, 2020 | 02:54h | UTC
European Consensus-based Interdisciplinary Guideline for Melanoma
17 Jan, 2020 | 02:50h | UTC
Observational Study: Patient-Reported Outcomes Through 5 Years for Active Surveillance, Surgery, Brachytherapy, or External Beam Radiation for Localized Prostate Cancer
16 Jan, 2020 | 08:53h | UTCPatient-Reported Outcomes Through 5 Years for Active Surveillance, Surgery, Brachytherapy, or External Beam Radiation With or Without Androgen Deprivation Therapy for Localized Prostate Cancer – JAMA (free for a limited period)
Related Study: Ten-year Outcomes in Men with Localized Prostate Cancer from the ProtecT Randomized Controlled Trial According to Treatment Received (free)
Commentaries: Prostatectomy-associated urinary incontinence disparities persist at 5 years – MedwireNews (free) AND Prostate Cancer Treatment Side Effects Worse With Prostatectomy – Renals & Urology News (free)
Randomized Trial: Behavioral Intervention to Increase Vegetable Consumption Does Not Affect Cancer Progression Among Men with Early-Stage Prostate Cancer
16 Jan, 2020 | 08:55h | UTCEffect of a Behavioral Intervention to Increase Vegetable Consumption on Cancer Progression Among Men With Early-Stage Prostate Cancer: The MEAL Randomized Clinical Trial – JAMA (free for a limited period)
Commentaries: Eating more vegetables provides no extra protection for men with prostate cancer – News Medical (free) AND Does Increased Vegetable Consumption Affect Prostate Cancer Progression? – MedicalResearch.com (free)
Among men with early-stage #prostatecancer managed with active surveillance, a behavioral intervention that increased vegetable consumption did not reduce risk of prostate cancer progression https://t.co/lUMNmHL6qG
— JAMA (@JAMA_current) January 15, 2020
The use of Antidepressants in Oncology: A Review and Practical Tips for Oncologists
16 Jan, 2020 | 02:39h | UTC
NCCN Guideline: Pediatric Acute Lymphoblastic Leukemia
16 Jan, 2020 | 02:42h | UTC
Position Statement on the Role of Percutaneous Ablation in Renal Cell Carcinoma
16 Jan, 2020 | 02:36h | UTC
[Abstract Only] Cohort Study: Colorectal Cancer in Ulcerative Colitis
16 Jan, 2020 | 02:34h | UTCColorectal cancer in ulcerative colitis: a Scandinavian population-based cohort study – The Lancet (link to abstract – $ for full-text)
Commentary: Association Between Colorectal Cancer and Ulcerative Colitis – The ASCO Post (free)