Oncology (all articles)
It’s World Cancer Day – 4 February 2020 / Report: WHO Outlines Steps to Save 7 Million Lives from Cancer
4 Feb, 2020 | 07:57h | UTCWHO outlines steps to save 7 million lives from cancer – World Health Organization (free)
See Report: World Cancer Report: Cancer Research for Cancer Prevention – World Health Organization (free PDF)
Related: Is the world making progress against cancer? – Our World in Data (free)
Modeling Analysis: Mortality Impact of Achieving WHO Cervical Cancer Elimination Targets
2 Feb, 2020 | 20:07h | UTCRelated Study: Impact of HPV vaccination and cervical screening on cervical cancer elimination: a comparative modelling analysis in 78 low-income and lower-middle-income countries – The Lancet (free)
Commentaries: New estimates of the number of cervical cancer cases and deaths that could be averted in low-income and lower-middle-income countries by scale-up of screening and vaccination activities – International Agency for Research on Cancer (free) AND Mass cervical cancer vaccine rollout could save 62 million lives in next 100 years – The Guardian (free)
European Consensus Recommendation: Prophylaxis and Management of GVHD after Stem-cell Transplantation for Hematological Malignancies
2 Feb, 2020 | 19:51h | UTCProphylaxis and management of graft versus host disease after stem-cell transplantation for haematological malignancies: updated consensus recommendations of the European Society for Blood and Marrow Transplantation – The Lancet Haematology (free registration required)
Perspective: When Is a Suboptimal Approach to Cancer Screening Better Than None in Low- and Middle-income Countries?
2 Feb, 2020 | 19:48h | UTCWhen Is a Suboptimal Approach to Cancer Screening Better Than None? – AMA Journal of Ethics (free)
See Special Issue: Global Burden of Cancer Inequality – AMA Journal of Ethics (free articles)
20-Year Follow-up of a Phase 3 RCT: High-Dose Chemotherapy with Hematopoietic Stem Cell Transplant in Patients With High-Risk Breast Cancer and 4 or More Involved Axillary Lymph Nodes
2 Feb, 2020 | 19:46h | UTCHigh-Dose Chemotherapy With Hematopoietic Stem Cell Transplant in Patients With High-Risk Breast Cancer and 4 or More Involved Axillary Lymph Nodes: 20-Year Follow-up of a Phase 3 Randomized Clinical Trial – JAMA Oncology (free for a limited period)
Commentary: Could High-Dose Chemo Return for Select Breast Cancers? – MedPage Today (free registration required)
ESMO Consensus Recommendations: Management of Cardiac Disease in Cancer Patients Throughout Oncological Treatment
31 Jan, 2020 | 01:38h | UTCRelated guidelines: Cardio-Oncology: Vascular and Metabolic Perspectives: A Scientific Statement from the American Heart Association – Circulation (free PDF) AND Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Cardio-Onco-Hematology in Clinical Practice. Position Paper and Recommendations – Revista Espanola de Cardiologia (free)
[Abstract Only] Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain
31 Jan, 2020 | 01:26h | UTCCannabinoids for adult cancer-related pain: systematic review and meta-analysis – BMJ Supportive & Palliative Care (link to abstract – $ for full-text)
Commentary: Cannabinoids No Help for Cancer Pain, Concludes Meta-Analysis – Medscape (free registration required)
Related: NICE Guideline: Cannabis-Based Medicinal Products (free guideline and resources on the subject)
Consensus Conference: Management of Patients with Advanced Prostate Cancer
31 Jan, 2020 | 01:05h | UTC
Consensus Guideline: Management of Desmoid Tumors
31 Jan, 2020 | 01:04h | UTC
A Network Meta-analysis of Maintenance Therapy in Chronic Lymphocytic Leukemia
31 Jan, 2020 | 00:54h | UTCA network meta-analysis of maintenance therapy in chronic lymphocytic leukemia – PLOS One (free)
[Abstract Only] Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial
30 Jan, 2020 | 07:47h | UTCReduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Findings from NELSON trial affirm benefits of CT lung screening – AuntMinnie.com (free)
[Abstract Only] Randomized Trial: Treatment of Helicobacter Pylori Reduces Gastric Cancer Among Patients with Positive Family History
30 Jan, 2020 | 07:39h | UTCFamily History of Gastric Cancer and Helicobacter pylori Treatment – New England Journal of Medicine (link to abstract – $ for full-text)
Visual Abstract: Family History of Gastric Cancer and Helicobacter pylori Treatment (free)
Commentary: Antibiotic therapy cuts stomach cancer rate by more than half in high-risk population – Reuters (free)
NICE Guideline: Colorectal Cancer
30 Jan, 2020 | 07:38h | UTCColorectal cancer – National Institute for Health and Care Excellence (free)
ASCO Guideline: Therapy for Stage IV Non–Small-Cell Lung Cancer Without Driver Alterations
30 Jan, 2020 | 07:27h | UTC
ASCO Guideline: Bone Health and Bone-Targeted Therapies for Prostate Cancer
30 Jan, 2020 | 07:26h | UTC
ASCO Guideline: Germline and Somatic Tumor Testing in Epithelial Ovarian Cancer
29 Jan, 2020 | 08:10h | UTC
Estimating the Magnitude of Cancer Overdiagnosis in Australia
28 Jan, 2020 | 08:59h | UTCEstimating the magnitude of cancer overdiagnosis in Australia – Medical Journal of Australia (free)
Commentary: 29,000 cancers overdiagnosed in Australia in a single year – The Conversation (free)
Related: Overdiagnosis: what it is and what it isn’t – BMJ Evidence Based Medicine (free) AND Overdiagnosis across medical disciplines: a scoping review – The BMJ Open (free) AND Too much medical care: bad for you, bad for health care systems – STAT News (free) AND Position Paper on Overdiagnosis and Action to be Taken – Wonca (free PDF) AND Screening: How overdiagnosis and other harms can undermine the benefits – Health News Review (free) AND Overdiagnosis: causes and consequences in primary health care – Canadian Family Physician (free) AND Five warning signs of overdiagnosis – The Conversation (free) AND What is overdiagnosed cancer? And why does it matter? – Croakey (free) AND Blame rising cancer overdiagnosis on ‘irrational exuberance’ for early detection – STAT (free) AND Preventing overdiagnosis and the harms of too much sport and exercise medicine – British Journal of Sports Medicine (free)
Reverse Cardio‐Oncology: Cancer Development in Patients With Cardiovascular Disease
28 Jan, 2020 | 08:53h | UTC
Studies: Whole-body MRI Compared with Standard Pathways for Staging Metastatic Disease in Lung and Colorectal Cancer
26 Jan, 2020 | 22:44h | UTCOriginal Studies: Whole body MRI for Colorectal and Lung Cancer Staging (free studies and commentaries)
Source: EvidenceAlerts
“In colorectal and non-small-cell lung cancer, the whole-body magnetic resonance imaging staging pathway has similar accuracy to standard staging pathways, is generally preferred by patients, improves staging efficiency and has lower staging costs.”
ASCO Guideline: Molecular Biomarkers in Localized Prostate Cancer
23 Jan, 2020 | 02:00h | UTCMolecular Biomarkers in Localized Prostate Cancer: ASCO Guideline – Journal of Clinical Oncology (free)
ASCO Guideline: Lung Cancer Surveillance After Definitive Curative-Intent Therapy
23 Jan, 2020 | 02:01h | UTC
[Abstract Only] Randomized Trial: Cabazitaxel vs. Abiraterone or Enzalutamide in Metastatic Prostate Cancer
23 Jan, 2020 | 01:48h | UTCCabazitaxel versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: ESMO 2019: Cabazitaxel vs Abiraterone or Enzalutamide in Previously Treated Metastatic Castration-Resistant Prostate Cancer – The ASCO Post (free)
Related Commentary on Twitter
#VisualAbstract: Cabazitaxel in Metastatic Prostate Cancer. See more NEJM Visual Abstracts now: pic.twitter.com/nUeb6dqRYi
— NEJM (@NEJM) December 26, 2019
Opinion: Our Best Weapons Against Cancer are Not Magic Bullets
22 Jan, 2020 | 09:23h | UTCOur best weapons against cancer are not magic bullets – Nature (free)
Immune Checkpoint Inhibitor Myocarditis: Pathophysiological Characteristics, Diagnosis, and Treatment
22 Jan, 2020 | 09:15h | UTCRelated: Cardiotoxicity of immune checkpoint inhibitors – ESMO Open (free) AND Cardiotoxicity from immune checkpoint inhibitors – IJC Heart & Vasculature (free) AND Cardiovascular toxicity of immune checkpoint inhibitors in cancer patients: A review when cardiology meets immuno-oncology – Journal of the Formosan Medical Association (free) AND Immune-Checkpoint Inhibitor-Induced Fulminant Myocarditis and Cardiogenic Shock – JACC: CardioOncology (free)
[Abstract Only] Randomized Trial: Effects of Addition of Anti-thymocyte Globulin to Standard Graft-versus-host Disease Prophylaxis in Patients with Hematological Malignancies Undergoing Transplantation from Unrelated Donor
22 Jan, 2020 | 09:16h | UTCAddition of anti-thymocyte globulin to standard graft-versus-host disease prophylaxis versus standard treatment alone in patients with haematological malignancies undergoing transplantation from unrelated donors: final analysis of a randomised, open-label, multicentre, phase 3 trial – The Lancet Haematology (link to abstract – $ for full-text)