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Oncology (all articles)

Expert Analysis: Vascular toxicities of novel cancer therapies.

24 May, 2022 | 07:50h | UTC

Vascular Toxicities of Novel Cancer Therapies – American College of Cardiology

 

NCCN Clinical Practice Guidelines in Oncology: 2022 Updates.

23 May, 2022 | 01:37h | UTC

NCCN Clinical Practice Guidelines in Oncology: 2022 Updates – The ASCO Post

 

Observational study suggests hepatic arterial infusion pump chemotherapy may be an alternative to resection for patients with multifocal intrahepatic cholangiocarcinoma.

23 May, 2022 | 00:52h | UTC

Comparison of Hepatic Arterial Infusion Pump Chemotherapy vs Resection for Patients With Multifocal Intrahepatic Cholangiocarcinoma – JAMA Surgery (link to abstract – $ for full-text)

Commentaries:

Hepatic Arterial Infusion Pump Chemotherapy vs Resection for Multifocal Intrahepatic Cholangiocarcinoma – The ASCO Post

Treating iCCA With Chemo Pump Can Be as Effective as Surgery, JAMA Study Finds – AJMC

 

Commentaries on Twitter

https://twitter.com/JAMASurgery/status/1524872044827000836

https://twitter.com/SyedAAhmad5/status/1527034049721663489

 

Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers.

23 May, 2022 | 01:16h | UTC

Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers – Nature Communications

Commentaries:

Researchers show the feasibility of a comprehensive sequencing approach in pediatric and young adult cancers – News Medical / Memorial Sloan Kettering Cancer Center

Study Points to Expanded Genomic Testing to Benefit Children and Young Adults With Cancer – The ASCO Post

 

Commentary from the author on Twitter (thread – click for more)

 

Cohort Study: Effect of awake craniotomy in glioblastoma in eloquent areas.

23 May, 2022 | 00:40h | UTC

Effect of awake craniotomy in glioblastoma in eloquent areas (GLIOMAP): a propensity score-matched analysis of an international, multicentre, cohort study – the Lancet Oncology (link to abstract – $ for full-text)

Commentary: Neurologic and Survival Outcomes After Awake Craniotomy for Glioblastoma – The ASCO Post

 

Commentary on Twitter

 

RCT: Elacestrant (oral selective estrogen receptor degrader) vs. standard endocrine therapy for estrogen receptor–positive, human epidermal growth factor receptor 2–negative advanced breast cancer.

20 May, 2022 | 10:55h | UTC

Elacestrant (oral selective estrogen receptor degrader) Versus Standard Endocrine Therapy for Estrogen Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer: Results From the Randomized Phase III EMERALD Trial – Journal of Clinical Oncology

Commentary: EMERALD Trial: Oral Selective Estrogen Receptor Degrader as Second- or Third-Line Therapy for Advanced Breast Cancer – The ASCO Post

 

Mammographic breast density, benign breast disease, and subsequent breast cancer risk in 3.9 million Korean women.

19 May, 2022 | 10:51h | UTC

Mammographic Breast Density, Benign Breast Disease, and Subsequent Breast Cancer Risk in 3.9 Million Korean Women – Radiology

News Release: Density, benign disease raise risk of breast cancer – Radiological Society of North America

 

Study designs for clinical trials applied to personalized medicine: a scoping review.

19 May, 2022 | 10:36h | UTC

Study designs for clinical trials applied to personalised medicine: a scoping review – BMJ Open

 

Review | Esophageal adenocarcinoma: A dire need for early detection and treatment.

19 May, 2022 | 10:24h | UTC

Esophageal adenocarcinoma: A dire need for early detection and treatment – Cleveland Clinic Journal of Medicine

 

Review: Managing metastatic melanoma in 2022.

19 May, 2022 | 10:23h | UTC

Managing Metastatic Melanoma in 2022: A Clinical Review – JCO Oncology Practice

 

Commentary on Twitter

 

The current and future incidence and mortality of gastric cancer in 185 countries, 2020–40: A population-based modelling study.

19 May, 2022 | 10:19h | UTC

The current and future incidence and mortality of gastric cancer in 185 countries, 2020–40: A population-based modelling study – eClinicalMedicine

 

Hair safe study: Effects of scalp cooling on hair preservation and hair regrowth in breast cancer patients receiving chemotherapy – A prospective interventional study.

19 May, 2022 | 10:15h | UTC

Hair safe study: Effects of scalp cooling on hair preservation and hair regrowth in breast cancer patients receiving chemotherapy – A prospective interventional study – The Breast

 

RCT: The addition of androgen deprivation therapy and pelvic lymph node treatment to prostate bed salvage radiotherapy.

18 May, 2022 | 10:49h | UTC

The addition of androgen deprivation therapy and pelvic lymph node treatment to prostate bed salvage radiotherapy (NRG Oncology/RTOG 0534 SPPORT): an international, multicentre, randomised phase 3 trial – The Lancet (link to abstract – $ for full-text)

 

M-A: Comparison of radiofrequency ablation vs. cryoablation For T1 renal tumors.

18 May, 2022 | 10:25h | UTC

Comparison of Radiofrequency Ablation Versus Cryoablation For T1 Renal Tumors: An Evidence-Based Analysis of Comparative Outcomes – Frontiers in Oncology

 

Nonrandomized Controlled Trial: Clinical impact of intraoperative margin assessment in breast-conserving surgery with a novel Pegulicianine Fluorescence–guided system.

18 May, 2022 | 10:28h | UTC

Clinical Impact of Intraoperative Margin Assessment in Breast-Conserving Surgery With a Novel Pegulicianine Fluorescence–Guided System: A Nonrandomized Controlled Trial – JAMA Surgery

 

Commentary on Twitter

 

Cohort Study: Survival outcomes associated with cytoreductive nephrectomy in patients with metastatic clear cell renal cell carcinoma.

17 May, 2022 | 10:41h | UTC

Survival Outcomes Associated With Cytoreductive Nephrectomy in Patients With Metastatic Clear Cell Renal Cell Carcinoma – JAMA Network Open

 

Commentary on Twitter

 

RCT: Effect of robot-assisted radical cystectomy with intracorporeal urinary diversion vs. open radical cystectomy on 90-day morbidity and mortality among patients with bladder cancer.

16 May, 2022 | 02:35h | UTC

Effect of Robot-Assisted Radical Cystectomy With Intracorporeal Urinary Diversion vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients With Bladder Cancer: A Randomized Clinical Trial – JAMA

Editorial: Robotic Surgery for Bladder Cancer – JAMA

 

Commentary on Twitter

 

[News release – not published yet] Gallstone disease shown to be a strong predictor of pancreatic cancer.

16 May, 2022 | 01:49h | UTC

Gallstone disease shown to be a strong predictor of pancreatic cancer – American Gastroenterology Association

 

Risk-adapted modulation through de-intensification of cancer treatments: an ESMO classification.

16 May, 2022 | 01:39h | UTC

Risk-adapted modulation through de-intensification of cancer treatments: an ESMO classification – Annals of Oncology

 

Commentary on Twitter

Under a CC BY-NC-ND 4.0 license

 

M-A: Electronic health interventions for patients with breast cancer.

16 May, 2022 | 01:16h | UTC

Electronic Health Interventions for Patients With Breast Cancer: Systematic Review and Meta-Analyses – Journal of Clinical Oncology

 

AUA/ASTRO Guideline: Clinically localized prostate cancer.

13 May, 2022 | 11:10h | UTC

Homepage: Clinically Localized Prostate Cancer: AUA/ASTRO Guideline – American Urological Association

Part I: Introduction, Risk Assessment, Staging and Risk-Based Management

Part II: Principles of Active Surveillance, Principles of Surgery, and Follow-Up

Part III: Principles of Radiation and Future Directions

Related:

Systematic Review of Active Surveillance for Clinically Localised Prostate Cancer to Develop Recommendations Regarding Inclusion of Intermediate-risk Disease, Biopsy Characteristics at Inclusion and Monitoring, and Surveillance Repeat Biopsy Strategy – European Urology

Therapies for Clinically Localized Prostate Cancer: A Comparative Effectiveness Review – The Journal of Urology

High-dose radiotherapy and risk-adapted androgen deprivation in localised prostate cancer (DART 01/05): 10-year results of a phase 3 randomised, controlled trial – The Lancet Oncology

German S3 Evidence-Based Guidelines on Focal Therapy in Localized Prostate Cancer: The First Evidence-Based Guidelines on Focal Therapy – Urologia Internationalis

Therapies for Clinically Localized Prostate Cancer – Agency for Healthcare Research and Quality

Radical prostatectomy versus deferred treatment for localised prostate cancer – Cochrane Library

 

RCT: Treatment with Etirinotecan pegol for patients with metastatic breast cancer and brain metastases.

13 May, 2022 | 10:51h | UTC

Treatment With Etirinotecan Pegol for Patients With Metastatic Breast Cancer and Brain Metastases: Final Results From the Phase 3 ATTAIN Randomized Clinical Trial – JAMA Oncology (free for a limited period)

 

Commentary on Twitter

 

Review: Eponyms in medical oncology.

13 May, 2022 | 10:45h | UTC

Eponyms in medical oncology – Cancer Treatment and Research Communications

 

Special Issue | Multicancer early detection: accelerating progress through international collaboration.

13 May, 2022 | 10:46h | UTC

Homepage: Multicancer Early Detection: Accelerating Progress Through International Collaboration

Multicancer early detection: International summit to Clarify the Roadmap

Multicancer early detection test: Preclinical, translational, and clinical evidence–generation plan and provocative questions

International perspectives on the development, application, and evaluation of a multicancer early detection strategy

Development and evaluation of safety and effectiveness of novel cancer screening tests for routine clinical use with applications to multicancer detection technologies

Evaluating the impact of multicancer early detection testing on health and economic outcomes: Toward a decision modeling strategy

Patient engagement and advocacy considerations in development and implementation of a multicancer early detection program

Industry engagement: Accelerating discovery, application, and adoption through industry partnerships

Related:

Opinion | Liquid biopsy: misplaced faith in early cancer detection?

Liquid Biopsy: Still Early Days for Early Detection

Opinion: New cancer test isn’t ready for prime time

Detection of Surgically Resectable Cancers with a Multi-analyte Blood Test

 

ASTRO Guideline: Radiation therapy for brain metastases.

12 May, 2022 | 10:11h | UTC

Radiation Therapy for Brain Metastases: An ASTRO Clinical Practice Guideline – Practical Radiation Oncology

News Release: ASTRO issues clinical guideline on radiation therapy for brain metastases – American Society for Radiation Oncology

 

Commentary on Twitter

 

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