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Neurology

Research: Traumatic Brain Injury and the Risk of Dementia Diagnosis

5 Feb, 2018 | 16:16h | UTC

Traumatic brain injury and the risk of dementia diagnosis: A nationwide cohort study – PLOS One (free)

Commentaries: TBI is associated with increased dementia risk for decades after injury – PLOS, via ScienceDaily (free) AND More evidence traumatic brain injuries raise later dementia risk – Reuters (free)

“Using longitudinal, case-control, and sibling-matched analyses of nationwide data from Sweden, Peter Nordström & Anna Nordström describe the association between TBI and dementia, its time course, and the influence of familial factors”. (via @PLOSMedicine see Tweet)

 


Research: HbA1c, Diabetes and Cognitive Decline

5 Feb, 2018 | 16:10h | UTC

HbA1c, diabetes and cognitive decline: the English Longitudinal Study of Ageing – Diabetologia (free)

Commentaries: The Startling Link Between Sugar and Alzheimer’s – The Atlantic (free) And Study Shows Long-Term Effects Of Diabetes And Prediabetes On The Brain – Forbes (free) AND New research shows diabetes and worse blood sugar control are associated with long-term cognitive decline – MedicalXpress (free) AND HbA1c Levels in Diabetes Linked to Cognitive Decline – Medscape (free registration required)

 


Review: Frontotemporal Dementia

4 Feb, 2018 | 16:58h | UTC

Frontotemporal dementia: latest evidence and clinical implications – Therapeutic Advances in Psychopharmacology (free)

 


2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke

26 Jan, 2018 | 01:44h | UTC

2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association (free PDF)

Commentaries: More stroke patients eligible for crucial treatments under new guidelines – American Heart Association News (free) AND More stroke patients may receive crucial treatments under new guideline – AHA/ASA Newsroom (free)

“A new guideline for treating acute ischemic stroke recommends an increased treatment window for mechanical clot removal from six hours to up to 24 hours in certain patients with clots in large vessels”. (from AHA/ASA Newsroom)

 


Research: Association of Time to Treatment With Short-term Outcomes for Pediatric Patients With Refractory Convulsive Status Epilepticus

26 Jan, 2018 | 01:39h | UTC

Association of Time to Treatment With Short-term Outcomes for Pediatric Patients With Refractory Convulsive Status Epilepticus – JAMA Neurology (free for a period)

Editorial: Time May Be of the Essence in the Treatment of Pediatric Patients With Refractory Convulsive Status Epilepticus (free)

Commentary: Delays Raise Death Risk in Kids with Status Epilepticus – MedPage Today (free registration required)

“These findings may change the perception of acute seizure and status epilepticus treatment, tentatively converting it into an extremely time-sensitive emergency that is similar to stroke or other cardiovascular events”.

 


Research: Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging

26 Jan, 2018 | 01:43h | UTC

Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging – New England Journal of Medicine (free)

Commentaries: Brain-scan guided emergency stroke treatment can save more lives – NIH News Releases (free) AND Study confirms late clot extraction can save brain cells of stroke victims – Reuters (free) AND New Findings Could Save Lives of More Stroke Patients – The New York Times (10 articles per month are free)

Related article: Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct – New England Journal of Medicine (link to abstract – $ for full-text)

 


Guideline on the Pharmacological Treatment of People with Multiple Sclerosis

26 Jan, 2018 | 01:33h | UTC

ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis – European Journal of Neurology (free)

 


Systematic Review: Whole Brain Radiotherapy for the Treatment of Newly Diagnosed Multiple Brain Metastases

26 Jan, 2018 | 00:01h | UTC

Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases – Cochrane Library (link to abstract – $ for full-text)

 


Guideline: Neuroendovascular Management of Emergent Large Vessel Occlusion

25 Jan, 2018 | 20:58h | UTC

Neuroendovascular management of emergent large vessel occlusion: update on the technical aspects and standards of practice by the Standards and Guidelines Committee of the Society of NeuroInterventional Surgery (free)

 


Review: Parkinson’s Disease in the ED

23 Jan, 2018 | 14:34h | UTC

Parkinson’s disease in the ED: a potpourri of hyperpyrexia, dyskinesias, psychosis, and autonomic dysfunction – emDocs (free)

 


Spreading Innovative Approaches to Dementia Care

23 Jan, 2018 | 14:34h | UTC

In Focus: Spreading Innovative Approaches to Dementia Care – Commonwealth Fund (free)

See other articles in the series: Transforming Care: Reporting on Health System Improvement (free)

 


Systematic Review: Poststroke Psychosis

23 Jan, 2018 | 14:15h | UTC

Poststroke psychosis: a systematic review – Journal of Neurology, Neurosurgery & Psychiatry (free)

 


Review: Combining Intravenous Thrombolysis and Antithrombotic Agents in Stroke?

23 Jan, 2018 | 14:05h | UTC

Combining Intravenous Thrombolysis and Antithrombotic Agents in Stroke: An Update – Journal of the American Heart Association (free)

 


Review: Interventions to Improve Movement and Functional Outcomes in Adult Stroke Rehabilitation

23 Jan, 2018 | 13:57h | UTC

Interventions to Improve Movement and Functional Outcomes in Adult Stroke Rehabilitation: Review and Evidence Summary – Journal of Participatory Medicine (free)

 


Research: New Prognostic Tool for Aneurysmal Subarachnoid Hemorrhage

23 Jan, 2018 | 13:47h | UTC

Development and validation of outcome prediction models for aneurysmal subarachnoid haemorrhage: the SAHIT multinational cohort study – The BMJ (free)

See prognostic calculator: Prediction models for 3 month outcome after aSAH

 

 


Review: Amyotrophic Lateral Sclerosis

16 Jan, 2018 | 19:07h | UTC

Amyotrophic lateral sclerosis – Nature Reviews, Disease Primers (free)

 


Meta-Analysis: Subclinical Device-Detected Atrial Fbrillation and Stroke Risk

16 Jan, 2018 | 18:29h | UTC

Subclinical device-detected atrial fibrillation and stroke risk: a systematic review and meta-analysis – European Heart Journal (free)

See related opinion and commentaries in Get Ready For A Tsunami Of ECGs

 


Research: Folic Acid Supplementation During Pregnancy and Risk of Autism in Children Exposed to Antiepileptic Drugs In Utero

16 Jan, 2018 | 17:32h | UTC

Association of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero – JAMA Neurology (link to abstract – $ for full-text)

Commentaries: Lack of Folic Acid Supplements During Pregnancy Linked With Increased Autism Risk in Children Exposed to Seizure Drugs In Utero – Medical Research (free) AND Folic Acid in Pregnant Women on Antiepileptic Drugs Linked to Lower Autism Risk – Medscape (free registration required) AND Folic Acid May Limit Autism Traits in Children of Epileptic Women – MedPage Today (free registration required) AND Folic acid lessens autism risk for fetal anti-epileptic exposure – MedicalXpress (free)

 


Review: Neurological Implications of Zika Virus Infection in Adults

16 Jan, 2018 | 17:11h | UTC

Neurological Implications of Zika Virus Infection in Adults – The Journal of Infectious Diseases (free)

 


Research: Contralateral Seventh Cervical Nerve Transfer for Spastic Arm Paralysis

16 Jan, 2018 | 13:20h | UTC

Trial of Contralateral Seventh Cervical Nerve Transfer for Spastic Arm Paralysis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Swapping cervical nerves – Richard Lehman’s journal reviews (free) AND Nerve Transfer May Restore Function in Stroke Victims – MedPage Today (free registration required)

 


Research: Triple Antiplatelet Therapy After Acute Cerebral Ischemia

16 Jan, 2018 | 13:00h | UTC

Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial – The Lancet (free)

Commentaries: Learning from TARDIS: time for more focused trials in stroke prevention – The Lancet (free) AND Triple Antiplatelets for Reducing Dependency After Ischaemic Stroke – TARDIS – American College of Cardiology, Latest in Cardiology (free)

“Among patients with recent cerebral ischaemia, intensive antiplatelet therapy did not reduce the incidence and severity of recurrent stroke or TIA, but did significantly increase the risk of major bleeding. Triple antiplatelet therapy should not be used in routine clinical practice”.

 


Research: Treatment Outcomes in Patients with Newly Diagnosed Epilepsy in a 30-Year Cohort Study

16 Jan, 2018 | 12:40h | UTC

Treatment Outcomes in Patients with Newly Diagnosed Epilepsy Treated With Established and New Antiepileptic Drugs: A 30-Year Longitudinal Cohort Study – The Lancet Neurology (link to abstract – $ for full-text)

Commentaries: Are We Getting Better at Controlling Epilepsy? – Emergency Medicine Literature of Note (free) AND More Than a Third of Patients Do Not Respond to Antiepileptics – Physician’s Weekly (free) AND Newer Epilepsy Drugs Haven’t Boosted Seizure Control – MedPage Today (free registration required) AND Epilepsy Treatment Outcomes Unchanged in Decades – Medscape (free registration required)

 


Diagnosis of Multiple Sclerosis: 2017 Revisions of the McDonald Criteria

13 Jan, 2018 | 19:05h | UTC

Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria – The Lancet Neurology (free registration required)

Commentaries: Diagnosing MS: Updates to the McDonald Criteria – Journal Watch (free) AND Revised ‘mcdonald criteria’ expected to speed the diagnosis of multiple sclerosis – MedicalXpress (free)

 


Meta-Analysis: Patent Forame Ovale Closure Tied to Lower Risk for Recurrent Stroke

10 Jan, 2018 | 23:15h | UTC

Percutaneous PFO Closure Tied to Lower Risk for Recurrent Stroke – Physician’s First Watch (free) AND Meta-Analyses Support Stroke Prevention With PFO Closure – MedPage Today (free registration required)

Original article 1: Device Closure Versus Medical Therapy Alone for Patent Foramen Ovale in Patients With Cryptogenic Stroke: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Original article 2: Percutaneous Closure Versus Medical Treatment in Stroke Patients With Patent Foramen Ovale: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

 


Research: Folic Acid Supplementation During Pregnancy and Risk of Autism in Children Exposed to Antiepileptic Drugs in Utero

10 Jan, 2018 | 00:32h | UTC

Association of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero – JAMA Neurology (link to abstract – $ for full-text)

Commentaries: Lack of Folic Acid Supplements During Pregnancy Linked With Increased Autism Risk in Children Exposed to Seizure Drugs In Utero – Medical Research (free) AND Folic Acid in Pregnant Women on Antiepileptic Drugs Linked to Lower Autism Risk – Medscape (free registration required) AND Folic Acid May Limit Autism Traits in Children of Epileptic Women – MedPage Today (free registration required) AND Folic acid lessens autism risk for fetal anti-epileptic exposure – MedicalXpress (free)

 


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