Neurology
Review – Multiple Sclerosis: Mechanisms and Immunotherapy
27 Feb, 2018 | 17:16h | UTCReview: Multiple Sclerosis: Mechanisms and Immunotherapy – Neuron (free)
Research: Bedtime Low Dose Amitriptyline in Chronic Neck Pain
27 Feb, 2018 | 15:44h | UTCRandomized double-blind controlled study of bedtime low dose amitriptyline in chronic neck pain – European Journal of Pain (link to abstract – $ for full-text)
Commentary: Low-dose amitriptyline reduces idiopathic chronic neck pain – Univadis (free registration required)
Research: Contribution of alcohol use disorders to the burden of dementia
23 Feb, 2018 | 01:00h | UTCCommentaries: Alcohol and dementia: a complex relationship with potential for dementia prevention – The Lancet Public Health (free) AND Expert reaction to study looking at alcohol use disorders and dementia risk – Science Media Centre (free) AND Heavy Drinking Tied to Early-Onset Dementia in French Study – MedPage Today (free registration required)
“Of 57,000 people diagnosed before age 65 with early-onset dementia, 39% had alcohol-related dementia by definition, and 18% had an additional diagnosis of alcohol use disorders” (via @medpagetoday see Tweet)
Guideline: Diagnosis and Treatment of Neurocysticercosis
22 Feb, 2018 | 23:39h | UTC
Benzodiazepines: Our Other Prescription Drug Epidemic
22 Feb, 2018 | 23:37h | UTCPerspective: Our Other Prescription Drug Problem – New England Journal of Medicine (free)
Related opinion: Benzodiazepines: our other prescription drug epidemic – STAT (free)
Research: Effect of Haloperidol on Survival Among Critically Ill Adults With a High Risk of Delirium
22 Feb, 2018 | 23:31h | UTCProphylactic haloperidol in this population with elevated risk of delirium did not reduce mortality or any of the 15 prespecified secondary outcomes, including delirium incidence, 28-day delirium-free and coma-free days, duration of mechanical ventilation, and ICU and hospital length of stay.
Review: Delirium in the Cardiac Intensive Care Unit
22 Feb, 2018 | 23:19h | UTCDelirium in the Cardiac Intensive Care Unit – Journal of the American Heart Association (free)
Source: Critical Care Reviews Newsletter
Heart Disease and Stroke Statistics
22 Feb, 2018 | 22:27h | UTCKey points: Heart Disease and Stroke Statistics—2018 Update – American College of Cardiology, Latest in Cardiology (free)
Research: Comparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy
22 Feb, 2018 | 21:52h | UTCComparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy – JAMA Pediatrics (link to abstract – $ for full-text)
Commentaries: Which Commonly Prescribed Drug is More Effective for Infants with Epilepsy? – Ann & Robert H. Lurie Children’s Hospital of Chicago, via NewsWise (free) AND Levetiracetam Bests Phenobarbital in Infantile Epilepsy – MedPage Today (free)
Syncope: ED Updates from the 2017 AHA/ACC/HRS Clinical Policy
22 Feb, 2018 | 21:50h | UTCSyncope: ED Updates from the 2017 AHA/ACC/HRS Clinical Policy – emDocs (free)
Review: When Psychiatric Symptoms Reflect Medical Conditions
22 Feb, 2018 | 21:47h | UTCSource: Critical Care Reviews Newsletter
Review: A Systematic Approach to the Unconscious Patient
22 Feb, 2018 | 21:43h | UTCA systematic approach to the unconscious patient – Clinical Medicine (free)
Source: Critical Care Reviews Newsletter
Systematic Review: Cranial Electrical Stimulation for Chronic Painful Conditions, Depression, Anxiety, and Insomnia
16 Feb, 2018 | 01:43h | UTCBenefits and Harms of Cranial Electrical Stimulation for Chronic Painful Conditions, Depression, Anxiety, and Insomnia: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Mild shock therapy may ease anxiety and depression, but not chronic pain – Reuters (free) AND Jury Still Out on CES for Depression, Anxiety, Pain, Insomnia – Medscape (free registration required)
Research: Risk of Dementia in Adults With Congenital Heart Disease
16 Feb, 2018 | 01:40h | UTCCommentaries: Congenital heart defects linked to increased risk of dementia – American Heart Association News (free) AND Adult Survivors of Congenital Heart Disease at Increased Risk of Dementia – TCTMD (free)
Research: Prognostic Effects of Delirium Motor Subtypes in Hospitalized Older Adults
16 Feb, 2018 | 00:52h | UTCPrognostic effects of delirium motor subtypes in hospitalized older adults: A prospective cohort study – PLOS One (free) (via @DrMeganHoseyPhD)
“One in three acutely ill hospitalized older adults who suffered hypoactive or mixed delirium died in the hospital”
Risky Antipsychotic Drugs Still Overprescribed In Nursing Homes
15 Feb, 2018 | 11:26h | UTCRisky Antipsychotic Drugs Still Overprescribed In Nursing Homes – NPR (free)
Original article: How Nursing Homes in the United States Overmedicate People with Dementia – Human Rights Watch (free)
Review: Air Pollution and Stroke
15 Feb, 2018 | 11:08h | UTCAir Pollution and Stroke – Journal of Stroke (free)
Review: Sleep Disturbances as a Risk Factor for Stroke
15 Feb, 2018 | 11:07h | UTCSleep Disturbances as a Risk Factor for Stroke – Journal of Stroke (free)
Review: Development of New Endovascular Devices for Aneurysm Treatment
15 Feb, 2018 | 11:06h | UTCDevelopment of New Endovascular Devices for Aneurysm Treatment – Journal of Stroke (free)
Review: Heart Failure as a Risk Factor for Stroke
15 Feb, 2018 | 11:06h | UTCHeart Failure as a Risk Factor for Stroke – Journal of Stroke (free)
Research: Five and 10 minute Apgar scores and risks of cerebral palsy and epilepsy
9 Feb, 2018 | 12:39h | UTCInfographic: The vital first 10 minutes (free PDF)
Even slight changes within the normal Apgar score range (7-10) from five to 10 minutes have a major influence in the risks of cerebral palsy and epilepsy.
Update: Stroke in Women
9 Feb, 2018 | 12:24h | UTC– Stroke in Women: Recognizing Opportunities for Prevention and Treatment – Stroke (free PDF for a limited period)
– Impact of Conventional Stroke Risk Factors on Stroke in Women – Stroke (free PDF for a limited period)
– Stroke Risk Factors Unique to Women – Stroke (free PDF for a limited period)
Research: Association of Preoperatively Diagnosed Patent Foramen Ovale With Perioperative Ischemic Stroke
9 Feb, 2018 | 12:17h | UTCAssociation of Preoperatively Diagnosed Patent Foramen Ovale With Perioperative Ischemic Stroke – JAMA (free for a period)
Commentaries: PFO Diagnosis Linked With Increased Risk of Perioperative Ischemic Stroke After Noncardiac Surgery – TCTMD (free) AND Preoperatively Diagnosed PFO and Perioperative Stroke – American College of Cardiology, Latest in Cardiology (free)
Research: High performance plasma amyloid-β biomarkers for Alzheimer’s disease
5 Feb, 2018 | 16:48h | UTCHigh performance plasma amyloid-β biomarkers for Alzheimer’s disease – Nature (link to abstract – $ for full-text)
Commentaries: Expert reaction to biomarkers for amyloid-beta in Alzheimer’s disease – Science Media Centre (free) AND A Big Step toward a Blood Test for Alzheimer’s – Scientific American (free) AND Simple blood test spots dementia protein – Nature News (free) AND Alzheimer’s hope as scientists unveil blood test for early signs – The Guardian (free)
Research: Migraine Associated with Increased Risk of Cardiovascular Diseases
5 Feb, 2018 | 16:47h | UTCMigraine and risk of cardiovascular diseases: Danish population based matched cohort study – The BMJ (free)
Editorial: Migraine and risk of cardiovascular disease (free)
Commentaries: Migraine Associated With Broad Range of CVD Diagnoses in Nationwide Study – TCTMD (free) AND Migraine Linked To Increased Risk of Stroke, AFib, PE and Cardiovascular Disease – MedicalResearch.com (free)