Neurology

“In routine clinical practice, endovascular treatment for patients with acute ischemic stroke is at least as effective and safe as in the setting of a randomized controlled trial”.

Research: Midlife cardiovascular fitness and dementia

16 Mar, 2018 | 02:07h | UTC

Midlife cardiovascular fitness and dementia: A 44-year longitudinal population study in women – Neurology (free)

Commentaries: High Cardiovascular Fitness in Midlife Tied to Lower Dementia Risk Later – NEJM Physician’s First Watch (free) AND Physically fit women nearly 90 percent less likely to develop dementia – American Academy of Neurology, via ScienceDaily (free)

Research: Socioeconomic disparities in first stroke incidence, quality of care, and survival

16 Mar, 2018 | 02:02h | UTC

Socioeconomic disparities in first stroke incidence, quality of care, and survival: a nationwide registry-based cohort study of 44 million adults in England – The Lancet Public Health (free)

Invited commentary: Preventing stroke on the street where you live, work, and play (free)

Patients from the lowest socioeconomic groups had first stroke a median of 7 years earlier than those from the highest and a 26% higher adjusted risk of 1-year mortality.

Implementation of the 2017 Berlin Concussion in Sport Group Consensus Statement in contact and collision sports

16 Mar, 2018 | 00:57h | UTC

Implementation of the 2017 Berlin Concussion in Sport Group Consensus Statement in contact and collision sports: a joint position statement from 11 national and international sports organisations – British Journal of Sports Medicine (free)

2018 AHA/ASA Ischemic Stroke Updates

8 Mar, 2018 | 22:26h | UTC

Summary for ED-relevant care: 2018 AHA/ASA Ischemic Stroke Updates – emDocs (free)

Original guideline: 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association (free PDF)

Randomized controled trial: Opioid vs Nonopioid Medications in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain

8 Mar, 2018 | 22:06h | UTC

Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain: The SPACE Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentaries: Opioids Don’t Beat Other Medications For Chronic Pain – NPR (free) AND More Data Opioids No Better for Chronic Back, Arthritis Pain – Medscape (free registration required) AND Opioids no better than NSAIDs for chronic back or arthritis pain – Reuters (free)

Guideline: Fluid therapy in neurointensive care patients

8 Mar, 2018 | 21:41h | UTC

Fluid therapy in neurointensive care patients: ESICM consensus and clinical practice recommendations – Intensive Care Medicine (free for a limited period) (via @luiscamacho02)

Research: Outcomes, experiences and palliative care in major stroke

8 Mar, 2018 | 21:32h | UTC

Outcomes, experiences and palliative care in major stroke: a multicentre, mixed-method, longitudinal study – Canadian Medical Association Journal (free)

““Palliative care” had connotations of treatment withdrawal and imminent death… practicing the principles of palliative care is needed, but the term “palliative care” should be avoided or reframed”.

Guidelines for the management of cryptococcal disease in HIV-infected adults, adolescents and children

8 Mar, 2018 | 21:30h | UTC

Guidelines for the diagnosis, prevention and management of cryptococcal disease in HIV-infected adults, adolescents and children – World Health Organization (free)

See also: Key Messages AND Policy Brief (free PDF)

Review: Progressive multifocal leukoencephalopathy

8 Mar, 2018 | 20:41h | UTC

Progressive multifocal leukoencephalopathy – Tidsskrift for Den norske legeforening (free)

Perioperative stroke: pathophysiology and management

8 Mar, 2018 | 20:24h | UTC

Perioperative stroke: pathophysiology and management – Synapse (free)

Source: Critical Care Reviews Newsletter

Meta-Analysis: Comparative Effectiveness and Safety of Cognitive Enhancers for Treating Alzheimer’s Disease

2 Mar, 2018 | 01:23h | UTC

Comparative Effectiveness and Safety of Cognitive Enhancers for Treating Alzheimer’s Disease: Systematic Review and Network Meta-analysis – Journal of the American Geriatrics Society (free)

Source: Medscape (free registration required)

“Cognitive enhancers in general have minimal effects on cognition according to minimal clinically important difference and global ratings. The drugs appear safe, but this must be interpreted cautiously because trial participants may have less comorbidity and fewer adverse effects than those treated with these drugs in clinical practice”.

Cohort Study: Epilepsy, antiepileptic drugs, and serious transport accidents

Educational attainment of children born to mothers with epilepsy

Expert consensus on arrhythmias and cognitive function

Stimulating the brain without surgery in the management of chronic pain in adults

Guideline on Subthalamic Nucleus and Globus Pallidus Internus Deep Brain Stimulation for the Treatment of Patients with Parkinson’s Disease

Guidelines for Elderly with Psychiatric & Neurologic Symptoms

Review: Neoplastic meningitis in solid tumors

Systematic Review: Treatment, Therapy and Management of Metabolic Epilepsy

Research: Risk of stroke in patients with dengue fever

Guidelines for Aneurysmal Subarachnoid Hemorrhage

Research: Endovascular treatment for acute ischaemic stroke in routine clinical practice