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Neurology

FDA Safety Alert: Neurovascular Stents in the Treatment of Unruptured Brain Aneurysms

14 May, 2018 | 11:57h | UTC

Neurovascular Stents Used for Stent-Assisted Coiling (SAC): Letter to Health Care Providers – Recommendations Associated With the Use of These Devices in the Treatment of Unruptured Brain Aneurysms – U.S. Food & Drug Administration (free)

Commentary: FDA Cautions on Stents for Unruptured Brain Aneurysms – NEJM Physician’s First Watch (free) AND FDA issues safety alert on stents used in aneurysm coiling – Univadis (free registration required)

 


Retrospective Cohort Studies: Risk of Stroke and TIA in Patients with Resolved Atrial Fibrillation

11 May, 2018 | 02:49h | UTC

Risk of stroke and transient ischaemic attack in patients with a diagnosis of resolved atrial fibrillation: retrospective cohort studies – The BMJ (free)

Commentaries: Tom Marshall: The importance of asking the right research question – BMJ Opinion (free) AND Patients who have had an irregular heart beat can’t ever be considered ‘cured’ – University of Birmingham (free)

 


Guideline Retraction: Parts of New AHA/ASA Acute Stroke Guidelines Rescinded

10 May, 2018 | 17:51h | UTC

Correction to: 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association – Stroke (free PDF)

Commentaries: AHA Rescinds Large Sections of New Stroke Guidelines – Medscape (free registration required) AND AHA/ASA retracts large portion of new stroke guidelines – Cardiovascular Business (free)

 


Cohort Study: Association of Mild Traumatic Brain Injury with Later Dementia

10 May, 2018 | 17:44h | UTC

Association of Mild Traumatic Brain Injury With and Without Loss of Consciousness With Dementia in US Military Veterans – JAMA Neurology (free for a limited period)

Editorial: Risk of Dementia Outcomes Associated With Traumatic Brain Injury During Military Service (free)

Commentaries: Dementia Risk Doubles Following Concussion, UCSF Study Shows – University of California San Francisco (free) AND Vets with Head Injury More Likely To Develop Dementia – MedicalResearch.com (free)

See two recent cohort studies with similar results: Long-term risk of dementia among people with traumatic brain injury (link to abstract and free commentaries) AND Traumatic Brain Injury and the Risk of Dementia Diagnosis (free article and commentaries)

 


Randomized Controlled Trial: Folic Acid for Stroke Prevention in High-Risk Hypertensive Patients

10 May, 2018 | 17:40h | UTC

Platelet Count Affects Efficacy of Folic Acid in Preventing First Stroke – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Folic acid ‘may help reduce stroke risk in people with high blood pressure’ – NHS Choices (free) AND Folic Acid Supplements May Reduce Stroke Risk in Hypertensive Patients – American College of Cardiology (free) AND Folic Acid Cut Strokes in Hypertensive Patients on Enalapril – MedPage Today (free registration required) AND Folic acid supplementation may help prevent first stroke in high-risk patients with hypertension – ACP Internist (free)

 


Perspective: Advanced Health Directives for Patients with Dementia

10 May, 2018 | 17:41h | UTC

Alzheimer’s? Your Paperwork May Not Be in Order – The New York Times (10 articles per month are free)

Related: New Document for Patients: Advanced Health Directive for Dementia (free document and commentaries)

 


SIGN Guideline: Pharmacological Management of Migraine

10 May, 2018 | 17:37h | UTC

Guideline: Pharmacological management of migraine – Scottish Intercollegiate Guidelines Network (free)

 


Cohort Study: Could Sauna Reduce Stroke Risk?

9 May, 2018 | 16:37h | UTC

Sauna bathing reduces the risk of stroke in Finnish men and women: A prospective cohort study – Neurology (link to abstract – $ for full-text)

Commentaries: Daily saunas may reduce stroke risk – NHS Choices (free) AND Can Saunas Lower Stroke Risk? – MedPage Today (free registration required) AND Could saunas reduce stroke risk? – Medical News Today (free)

 


Consensus: Programming Deep Brain Stimulation for Patients with Parkinson’s Disease

9 May, 2018 | 16:14h | UTC

Chinese expert consensus on programming deep brain stimulation for patients with Parkinson’s disease – Translational Neurodegeneration (free)

 


Review: 10 Strategies for the Prevention and Treatment of ICU Delirium

4 May, 2018 | 02:10h | UTC

Nonpharmacologic and Medication Minimization Strategies for the Prevention and Treatment of ICU Delirium: A Narrative Review – Journal of Intensive Care Medicine (free)

Source: Critical Care Reviews Newsletter

 


Randomized Non-inferiority Trial: Methods of TMS Compared in Patients with Depression

3 May, 2018 | 20:12h | UTC

Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Three-Minute Brain Stimulation Sessions Effectively Reduce Depression Symptoms, Study Finds – Forbes (free) AND Three Minute Version of Brain Stimulation Therapy Effective for Hard to Treat Depression – Neuroscience News (free)

 


AHA Scientific Statement: Indications for Intracranial Endovascular Neurointerventional Procedures

3 May, 2018 | 20:07h | UTC

Indications for the Performance of Intracranial Endovascular Neurointerventional Procedures: A Scientific Statement From the American Heart Association – Circulation (free PDF)

Key Points to Remember: Indications for Intracranial Endovascular Procedures – American College of Cardiology (free)

 


Systematic Review: Is Anxiety in Midlife a Risk Factor for Dementia?

3 May, 2018 | 19:59h | UTC

Support for midlife anxiety diagnosis as an independent risk factor for dementia: a systematic review – BMJ Open (free)

Commentaries: Moderate to severe mid-life anxiety may be linked to later life dementia – BMJ Open Blog (free) AND Anxiety in middle age linked to dementia later – Reuters (free) AND Expert reaction to a review of the association between mid-life anxiety and later life dementia – Science Media Centre (free)

“The current study isn’t designed to explain how anxiety and dementia might be connected, Iadecola added.

“We cannot say with confidence that anxiety is a cause (risk factor), an early manifestation of the dementia, or only coincidentally associated with it,”” (from Reuters)

 


Randomized Controlled Trial: Tenecteplase vs Alteplase before Thrombectomy for Ischemic Stroke

3 May, 2018 | 19:52h | UTC

Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Stroke: Which Clot Buster Drug Works Best? – MedicalResearch.com (free) AND Tenecteplase Appears Superior to Alteplase After Ischemic Stroke – Cardiology Advisor (free)

 


Meta-Analysis: Predictors of Post-stroke Fever and Infections

3 May, 2018 | 19:38h | UTC

Predictors of post-stroke fever and infections: a systematic review and meta-analysis – BMC Neurology (free)

Commentary: Predictors of poststroke pneumonia clarified – Univadis (free)

 


Systematic Review: Reminiscence Therapy for Dementia

3 May, 2018 | 18:46h | UTC

Reminiscence therapy for dementia – Cochrane Library (link to abstract – $ for full-text)

Summary: Reminiscence therapy for dementia (free)

Commentary: Featured Review: Reminiscence Therapy for Dementia – Cochrane Library (free)

 


Case-control Study: Anticholinergic Drugs and Risk of Dementia

27 Apr, 2018 | 02:38h | UTC

Anticholinergic drugs and risk of dementia: case-control study – The BMJ (free)

Editorial: Anticholinergic drugs and dementia in older adults (free)

Commentaries: Expert reaction to study investigating the association between different types of anticholinergic drugs and risk of dementia – Science Media Centre (free) AND Anticholinergic drugs may be linked to increased risk of dementia – OnMedica (free)

“The effect of anticholinergic therapy is relatively small (odds ratio 1.1 – 1.2) and establishing an association does not prove a causal link. Nevertheless, the paper may act as a useful guide for future research and clinical practice”. (by Prof Les Iversen, in Science Media Centre)

 


NICE Guideline Update: Neuropathic pain in adults

27 Apr, 2018 | 02:29h | UTC

Guideline Update: Neuropathic pain in adults: pharmacological management in non-specialist settings – National Institute for Health and Care Excellence (free)

 


NICE Guideline Update: Diagnosis and Management of Epilepsies

27 Apr, 2018 | 01:34h | UTC

Guideline Update: Epilepsies: diagnosis and management – National Institute for Health and Care Excellence (free)

 


Meta-Analysis: Case Managers Improve Outcomes for People with Dementia and Their Carers

27 Apr, 2018 | 01:23h | UTC

Case managers improve outcomes for people with dementia and their carers – NIHR Signal (free)

Original Article: The effectiveness of community-based coordinating interventions in dementia care: a meta-analysis and subgroup analysis of intervention components – BMC Health Services Research (free)

“The review suggests that nurses may be particularly well placed to act as case managers for people with dementia, perhaps because they have the skills to perform the broad range of tasks associated with the role.” (via @NIHR_DC see Tweet)

 


Research: Soccer Heading Frequency—Not Collisions—Linked to Cognitive Performance

25 Apr, 2018 | 13:35h | UTC

Heading Frequency Is More Strongly Related to Cognitive Performance Than Unintentional Head Impacts in Amateur Soccer Players – Frontiers in Neurology (free)

Commentary: Soccer Heading—Not Collisions—Cognitively Impairs Players – Albert Einstein College of Medicine (free)

Related Review: Effects of Soccer Heading on Brain Structure and Function – Frontiers in Neurology (free)

 


Viewpoint: Tube Feeding and Deteriorating Patients

25 Apr, 2018 | 12:54h | UTC

David Oliver: Tube feeding and deteriorating patients—guidelines can take us only so far – The BMJ (free)

Related Guidelines: American Geriatrics Society Feeding Tubes in Advanced Dementia Position Statement (free) AND ESPEN guideline on ethical aspects of artificial nutrition and hydration (free)

Related Reviews: Artificial nutrition and hydration in advanced dementia – Canadian Family Physician (free) AND End-of-life issues in advanced dementia: Part 1: goals of care, decision-making process, and family education – Canadian Family Physician (free) AND End-of-life issues in advanced dementia: Part 2: management of poor nutritional intake, dehydration, and pneumonia – Canadian Family Physician (free) AND Advanced Dementia – New England Journal of Medicine (free)

 


AAN Guideline: Disease-modifying Therapies for Adults with Multiple Sclerosis

24 Apr, 2018 | 19:33h | UTC

Practice guideline recommendations summary: Disease-modifying therapies for adults with multiple sclerosis – Neurology (free)

See also: Related Physician Tools and Materials (free clinician summary, slides and more)

Commentaries: New guideline: Start taking MS drugs early on – American Academy of Neurology, via EurekAlert (free)

New MS Guideline Addresses Starting, Switching, and Stopping Disease-modifying Therapy – MD Magazine (free) AND Start MS Drugs Early, New Guideline Says – MedPage Today (free registration required)

 


New International Classification of Headache Disorders

23 Apr, 2018 | 21:14h | UTC

Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition – Cephalalgia (free PDF) (via @adamcifu)

News release and website: The International Classification of Headache Disorders 3rd edition (free)

Commentary: International Classification of Headache Disorders – The Lancet Neurology (free)

 


New Glasgow Coma Scale–Pupils Score

23 Apr, 2018 | 21:10h | UTC

Simplifying the use of prognostic information in traumatic brain injury – Journal of Neurosurgery

Part 1: The GCS-Pupils score: an extended index of clinical severity (free)

Part 2: Graphical presentation of probabilities (free)

Commentaries: New Glasgow Coma Scale–Pupils Score and Multifactor Probability Outcome Charts for Use in Patients with TBI – Journal of Neurosurgery, via NewsWise (free) AND New scoring system will speed up assessment of brain injuries – OnMedica (free) AND Glasgow Coma Scale Gets an Eye-Opening Update – Medscape (free registration required)

 


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