Neurology
Review: Management of Chronic Inflammatory Demyelinating Polyradiculoneuropathy
6 Jun, 2018 | 21:26h | UTC
Systematic Review: Effects of Physical Exercise on Cognitive Function in Parkinson’s Disease
29 May, 2018 | 18:36h | UTC
Randomized Trial: New Treatment for Prevention of Episodic Migraine Assessed
29 May, 2018 | 18:30h | UTCEffect of Fremanezumab Compared With Placebo for Prevention of Episodic Migraine: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Fremanezumab effective in preventing episodic migraine – 2 Minute Medicine (free)
“Among patients with episodic migraine in whom multiple medication classes had not previously failed, subcutaneous fremanezumab, compared with placebo, resulted in a statistically significant 1.3- to 1.5-day reduction in the mean number of monthly migraine days over a 12-week period”. (from JAMA)
“The small effect size in terms of reduction in number of days with migraine dampens enthusiasm for this medication, though without head-to-head comparison against other prophylactics, this is hard to assess” (from 2 Minute Medicine)
Cohort Study: Vascular Risk Interacts with β-Amyloid Burden in the Progression of Cognitive Decline
28 May, 2018 | 12:44h | UTCInteractive Associations of Vascular Risk and β-Amyloid Burden With Cognitive Decline in Clinically Normal Elderly Individuals: Findings From the Harvard Aging Brain Study – JAMA Neurology (free for a limited period)
Commentaries: Vascular risk interacts with amyloid levels to increase age-related cognitive decline – Massachusetts General Hospital, via ScienceDaily (free) AND Bad Synergy—Together, Vascular Problems and Aβ Hasten Memory Slippage – AlzForum (free) AND Combo of vascular risk, brain amyloid could quicken mental decline – Cardiovascular Business (free)
Cohort Study: Inflammatory Bowel Disease Patients Have Higher Risk of Parkinson’s disease
24 May, 2018 | 22:37h | UTCCommentary: Inflammatory bowel disease may raise Parkinson’s risk – Medical News Today (free)
Review: Updates in Refractory Status Epilepticus
24 May, 2018 | 22:22h | UTCUpdates in Refractory Status Epilepticus – Critical Care Research and Practice (free)
Source: Critical Care Reviews Newsletter
Retrospective Cohort: Atrial Fibrillation Burden and Risk of Stroke in Adults with Paroxysmal Atrial Fibrillation
23 May, 2018 | 12:48h | UTCCommentaries: Atrial Fibrillation Burden and Stroke Risk – American College of Cardiology (free) AND Greater burden of atrial fibrillation linked to higher stroke risk – Kaiser Permanente, via EurekAlert (free)
Guideline: Use of Atraumatic Needles in All Patients Undergoing Lumbar Puncture
23 May, 2018 | 12:32h | UTCRapid Recommendations: Atraumatic (pencil-point) versus conventional needles for lumbar puncture: a clinical practice guideline – The BMJ (free)
“We issue a strong recommendation for use of atraumatic needles in all patients (adults and children) undergoing lumbar puncture because they decrease complications and are no less likely to work than conventional needles”
Research: Clinical Features of Guillain-Barré Syndrome With vs Without Zika Virus Infection
23 May, 2018 | 12:23h | UTCClinical Features of Guillain-Barré Syndrome With vs Without Zika Virus Infection, Puerto Rico, 2016 – JAMA Neurology (link to abstract – $ for full-text)
Commentary: Study: GBS symptoms more severe when caused by Zika – CIDRAP (free)
Perspective: Ten Dubious Beliefs in Neurocritical Care
23 May, 2018 | 12:26h | UTCTen dubious beliefs in neurocritical care – PulmCrit (free)
Randomized Trial: Cannabidiol Reduces Seizures in Patients with Lennox–Gastaut Syndrome
23 May, 2018 | 12:22h | UTCEffect of Cannabidiol on Drop Seizures in the Lennox–Gastaut Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Cannabidiol significantly reduces seizures in patients with severe form of epilepsy – NYU School of Medicine (free) AND Cannabis Drug Reduces Drop Seizures in Severe Epilepsy – Medscape (free registration required) AND Cannabidiol Significantly Reduces Seizures in Patients with Lennox-Gastaut Syndrome – MD Magazine (free)
Cohort Study: Five-Year Risk of Stroke after TIA or Minor Ischemic Stroke
18 May, 2018 | 02:39h | UTCFive-Year Risk of Stroke after TIA or Minor Ischemic Stroke – New England Journal of Medicine (free)
Commentary: Elevated Stroke Risk Continues for 5 Years After TIA – NEJM Physician’s First Watch (free) AND Five Years after TIA or Minor Stroke, Second-Event Risk Persists – MedPage Today (free)
Randomized Controlled Trial: Tranexamic Acid for Hyperacute Primary Intracerebral Hemorrhage
18 May, 2018 | 02:36h | UTCEditorial: Haemostatic treatment for intracerebral haemorrhage (free)
Commentaries: Study: Drug to treat bleeding may reduce stroke deaths – UPI (free) AND Drug to treat bleeding may benefit some stroke patients, study finds – University of Nottingham, via EurekAlert (free)
Randomized Trial: MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset
18 May, 2018 | 02:37h | UTCMRI-Guided Thrombolysis for Stroke with Unknown Time of Onset – New England Journal of Medicine (free)
Editorial: MRI-Guided Intravenous Alteplase for Stroke — Still Stuck in Time (free)
Commentary: New treatment option for ‘wake-up’ stroke patients – University of Glasgow, via MedicalXpress (free)
Randomized Trial: Rivaroxaban Not Effective for Stroke Prevention after Embolic Stroke of Undetermined Source
18 May, 2018 | 02:38h | UTCCommentaries: NAVIGATE ESUS: Rivaroxaban Fails to Prevent More Recurrent Cryptogenic Strokes Than Aspirin – TCTMD (free) AND Rivaroxaban Not Superior to Aspirin for Patients with Embolic Stroke of Unknown Source – NEJM Physician’s First Watch (free)
Randomized Trial: Dual Antiplatelet Therapy in Acute Ischemic Stroke and High-Risk TIA
18 May, 2018 | 02:36h | UTCClopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA – New England Journal of Medicine (free)
Editorial: Antiplatelet Therapy after Ischemic Stroke or TIA (free)
Commentary: Dual Antiplatelet Therapy or Aspirin Alone After TIA or Minor Stroke? – NEJM Physician’s First Watch (free)
Clinical Guideline: Pharmacotherapy for Neuropathic Pain
18 May, 2018 | 02:33h | UTC
Cohort Study: Chemotherapy-Induced Neuropathy in Survivors of Childhood Cancer
18 May, 2018 | 02:32h | UTCChemotherapy-Induced Peripheral Neuropathy in Long-term Survivors of Childhood Cancer: Clinical, Neurophysiological, Functional, and Patient-Reported Outcomes – JAMA Neurology (free for a limited period)
Commentaries: Peripheral Neuropathy Common in Childhood Cancer Survivors – MPR (free) AND Chemo-Induced Neuropathy Common after Childhood Cancer – MedPage Today (free registration required)
Randomized Controlled Trial: Exercise Training Does Not Slow Dementia Progression
18 May, 2018 | 02:29h | UTCCommentaries: Exercise Doesn’t Slow Cognitive Decline in Patients with Dementia – NEJM Physician’s First Watch (free) AND Rigorous exercise does not halt dementia decline, study concludes – The Guardian (free) AND Expert reaction to effects of exercise on dementia in old people – Science Media Centre (free) AND Exercise ‘doesn’t slow’ progression of dementia – NHS Choices (free)
Review: Intensive Care for Patients with Aneurysmal Subarachnoid Hemorrhage
16 May, 2018 | 01:21h | UTCSource: Critical Care Reviews Newsletter
Research: Amyloid PET Scan for Predicting Alzheimer’s Disease in Mild Cognitive Impairment
16 May, 2018 | 01:19h | UTCCommentaries: Biomarkers, PET imaging may predict cognitive decline en route to Alzheimer’s – Health Imaging (free) AND Amyloid PET Scan Can Predict Progression to Alzheimer’s in Patients With Mild Cognitive Impairment – MedicalResearch.com (free)
Related Studies: Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons (link to abstract and free commentaries) AND Identifying incipient dementia individuals using machine learning and amyloid imaging (free full-text and commentaries) AND High performance plasma amyloid-β biomarkers for Alzheimer’s disease (link to abstract and free commentaries)
Study: Visual Screening Tool Improves Prediction of Developing Dementia
16 May, 2018 | 01:18h | UTCImproving Prediction of Dementia in Primary Care – Annals of Family Medicine (free)
Commentaries: Screening Tool Improves Dementia Prediction – Medscape (free registration required) AND Visual Test Could Help Predict Dementia Risk in Elders – NEJM Physician’s First Watch (free)
Meta-Analysis: Transcranial Magnetic Stimulation for Stroke Survivors
16 May, 2018 | 00:38h | UTCCommentaries: For Stroke Victims, Brain Magnetic Stimulation Leads to Improved Walking Speed – Wolters Kluwer, via NewsWise (free) AND Stroke survivors may benefit from magnetic brain stimulation – Medical News Today (free)
Retrospective Cohort: Achieved Systolic BP and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus
16 May, 2018 | 00:35h | UTCEffect of Achieved Systolic Blood Pressure on Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus: A Population-Based Retrospective Cohort Study – Diabetes Care (link to abstract – $ for full-text)
Commentaries: Diabetics with lower achieved SBP may be at greater risk for cardiovascular disease – Cardiovascular Business (free) AND No reduced CVD risk for SBP <120 mm hg in type 2 diabetes – MedicalXpress (free)
Case–Control Study: Smoking and Risk of Ischemic Stroke in Young Men
14 May, 2018 | 18:03h | UTCSmoking and Risk of Ischemic Stroke in Young Men – Stroke (link to abstract – $ for full-text)
Commentaries: Even young men who smoke have increased stroke risk – Reuters (free) AND Number of Cigarettes Smoked per Day Influences Stroke Risk in Young Men – TCTMD (free) AND Men younger than 50: the more you smoke, the more you stroke – AHA/ASA Newsroom (free)