Neurology
Psychosis in systemic lupus erythematosus (SLE): a 40-year experience of a specialist center showed most patients (66.7%) had full remission with a combination of antipsychotics and immunosuppressive therapy.
4 Feb, 2022 | 08:20h | UTC
Consensus Statement: Preoperative management of medications for psychiatric diseases.
3 Feb, 2022 | 09:59h | UTC
M-A: Timing of tracheostomy in acute traumatic spinal cord injury.
3 Feb, 2022 | 08:44h | UTC
M-A: Timing of carotid intervention in symptomatic carotid artery stenosis.
3 Feb, 2022 | 08:33h | UTC
Using melatonin for sleep is on the rise, study says, despite potential health harms.
2 Feb, 2022 | 08:41h | UTCUsing melatonin for sleep is on the rise, study says, despite potential health harms – CNN
Original Study: Trends in Use of Melatonin Supplements Among US Adults, 1999-2018 – JAMA (free for a limited period)
Cohort Study: Association of posttraumatic epilepsy with 1-year outcomes after traumatic brain injury.
2 Feb, 2022 | 08:36h | UTC
Commentary on Twitter
In this cohort study, the incidence of self-reported posttraumatic #epilepsy after traumatic brain injury (TBI) was associated with unfavorable outcomes, highlighting the need to find effective antiepileptogenic therapies after #TBI. #PTE #TRACKTBI https://t.co/mxfd7oVQFN
— JAMA Network Open (@JAMANetworkOpen) December 29, 2021
Cluster Randomized Trial: In older patients undergoing elective surgical procedures, a multimodal nonpharmacological prevention program reduced postoperative delirium occurrence and days with delirium.
2 Feb, 2022 | 08:38h | UTCAuthor Interview: Effective Delirium Prevention in Older Persons After Elective Surgery
Commentary on Twitter
Study suggests implementing a multifaceted multidisciplinary prevention intervention will improve care and outcomes in older patients undergoing elective general and orthopedic procedures https://t.co/lHU59ca5m5 pic.twitter.com/oj76KiV4It
— JAMA Surgery (@JAMASurgery) December 15, 2021
Systematic Review: Non-operative treatment for lumbar spinal stenosis with neurogenic claudication.
2 Feb, 2022 | 08:08h | UTC
WHO Recommendations: Reducing the risk of cognitive decline and dementia.
1 Feb, 2022 | 09:50h | UTCReducing the Risk of Cognitive Decline and Dementia: WHO Recommendations – Frontiers in Neurology
Related:
New WHO toolkit promotes inclusion of people with dementia in society.
Dementia: number of people affected to triple in next 30 years – World Health Organization
Concussion management is changing as more research suggests exercise is the best approach.
1 Feb, 2022 | 08:27h | UTCRelated:
Guideline: Nonpharmacological treatment of persistent postconcussion symptoms in adults.
Randomized Trial: Early Aerobic Exercise for Sport-Related Concussion
RCT: Limiting screen time for young adults after concussion results in shorter duration of symptoms.
Guideline Summary: Management of the top 10 most common immune-related adverse events in patients treated with immune checkpoint inhibitor therapy.
30 Jan, 2022 | 14:11h | UTCOriginal Article: ASCO Guideline Update: Management of immune-related adverse events in patients treated with immune checkpoint inhibitor therapy.
Related:
Clinical practice guideline on immune checkpoint inhibitor-related adverse events.
NCCN Guidelines Insights: Management of Immunotherapy-Related Toxicities (several resources on the subject)
Review: Essential tremor.
30 Jan, 2022 | 14:08h | UTCEssential tremor – Nature Reviews Disease Primers (if the link is paywalled, try this one)
Infographic: Essential tremor (if the link is paywalled, try this one)
Commentary on Twitter
The brain circuits involved in #essentialtremor pathophysiology can be conceptualized as four intersecting pathways within the cerebellar #cortex https://t.co/Q45PjGCBdH pic.twitter.com/6Jo0XjViYC
— Nature Reviews Disease Primers (@DiseasePrimers) January 28, 2022
Differential levels of plasma biomarkers of neurodegeneration in Lewy body dementia, Alzheimer’s disease, frontotemporal dementia and progressive supranuclear palsy.
30 Jan, 2022 | 13:53h | UTCCommentary: Blood Biomarkers May Distinguish Dementia Disorders – MedPage Today (free registration required)
Guideline: Physical therapist management of Parkinson Disease.
28 Jan, 2022 | 08:23h | UTC
A nationwide, population-based case-control study showed dentist’s visits were not associated with increased risk of brain abscess.
28 Jan, 2022 | 07:58h | UTCDentist’s visits and risk of brain abscess: a nationwide, population-based case control study – Clinical Infectious Diseases (link to abstract – $ for full-text)
Commentary on Twitter
Finally💥
High-quality large-scale clinical study on brain abscess
Dentist’s visits & risk of brain abscess
Recent invasive dental procedures & number of dentist’s visits were NOT associated w culture verified brain abscess caused by oral cavity bacteria https://t.co/ziEke7eBYm— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) December 30, 2021
Cohort study: Among patients who survived ICU treatment for COVID-19, 75% still reported physical, mental, or cognitive symptoms after 1 year.
26 Jan, 2022 | 02:28h | UTCCommentaries:
75% of COVID ICU survivors have physical symptoms 1 year on – CIDRAP
Majority of COVID-19 survivors experience health problems one-year post ICU admission – News Medical
Review: Diagnosis and management of functional neurological disorder.
25 Jan, 2022 | 09:22h | UTCDiagnosis and management of functional neurological disorder – The BMJ
RCT: Safety and efficacy of Daridorexant in patients with insomnia disorder.
25 Jan, 2022 | 09:15h | UTCSafety and efficacy of daridorexant in patients with insomnia disorder: results from two multicentre, randomised, double-blind, placebo-controlled, phase 3 trials – The Lancet Neurology (link to abstract – $ for full-text)
Perspective: Nervous system consequences of COVID-19.
21 Jan, 2022 | 10:10h | UTCNervous system consequences of COVID-19 – Science
Related:
Review: Counting the neurological cost of COVID-19.
Neurological Effects of COVID-19 in Children.
International Registry: Ischemic and hemorrhagic stroke among critically ill patients with Covid-19.
Short review: Neurological complications of COVID-19.
2 new meta-analysis detail neurologic and psychiatric conditions in COVID-19.
M-A: Encephalitis as Neurological Complication of COVID‐19.
Large study finds 1 in 3 Covid-19 survivors have subsequent mental health and neurological conditionsEight out of ten people hospitalized with COVID-19 develop neurological problems – the most common self-reported symptoms included headache (37%) and anosmia or ageusia (26%).
Commentary on Twitter
A new #SciencePerspective discusses the neurological symptoms that accompany #COVID19 and the possible mechanisms that cause them. Read more: https://t.co/WKZpnWlbNc pic.twitter.com/U4ohecaVQd
— Science Magazine (@ScienceMagazine) January 20, 2022
Systematic Review: In people with Alzheimer’s disease and vascular dementia with agitation and psychosis, atypical antipsychotics probably reduce agitation slightly (moderate‐certainty evidence) but probably have a negligible effect on psychosis or risk of any adverse event.
21 Jan, 2022 | 09:50h | UTC
An updated overview of low back pain management.
21 Jan, 2022 | 09:23h | UTCAn Updated Overview of Low Back Pain Management – Asian Spine Journal
Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.
20 Jan, 2022 | 08:39h | UTCCannabis-Based Medicines and Medical Cannabis for Chronic Neuropathic Pain – CNS Drugs
Related:
Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain.
Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.
Guideline: Medical cannabis or cannabinoids for chronic pain.
NICE Guideline: Cannabis-Based Medicinal Products
Short Review: Drug Interactions with Cannabinoids
Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain
RCT: Safety and efficacy of lower-sodium oxybate in adults with idiopathic hypersomnia.
19 Jan, 2022 | 08:11h | UTCSafety and efficacy of lower-sodium oxybate in adults with idiopathic hypersomnia: a phase 3, placebo-controlled, double-blind, randomised withdrawal study – The Lancet Neurology (link to abstract – $ for full-text)
Perspective | Post-acute neurological consequences of COVID-19: an unequal burden – “COVID-19 and its neurological consequences particularly burden marginalized communities, and so can only be effectively treated by advancing health equity”.
18 Jan, 2022 | 09:44h | UTCPost-acute neurological consequences of COVID-19: an unequal burden – Nature Medicine
Multicenter observational study: Reconstruction of paralyzed arm function in patients with hemiplegia through contralateral seventh cervical nerve cross transfer.
18 Jan, 2022 | 09:13h | UTC