Neurology
Differentiating multiple sclerosis from AQP4-neuromyelitis optica spectrum disorder and MOG-antibody disease with imaging.
26 Oct, 2022 | 14:24h | UTC
Commentary on Twitter
Published online: Cortese @RosaCortese5 and colleagues assessed whether imaging characteristics typical of multiple sclerosis (#MS) discriminate relapsing remitting MS from AQP4-NMOSD and #MOGAD, alone and in combination. Learn more: https://t.co/AWYoEZQDP9 #NeuroTwitter pic.twitter.com/3Pytn45uLx
— Neurology Journal (@GreenJournal) October 12, 2022
Post-trial follow-up | Long-term treatment with Ponesimod in relapsing-remitting multiple sclerosis.
25 Oct, 2022 | 13:14h | UTCCommentary: Optimal Dose of Ponesimod for Control of Relapsing-Remitting Multiple Sclerosis – Neurology Advisor
Original Study: Oral ponesimod in relapsing–remitting multiple sclerosis: a randomised phase II trial – Journal of Neurology, Neurosurgery & Psychiatry
Guideline | Use of implantable peripheral nerve stimulation in the treatment of chronic pain.
21 Oct, 2022 | 13:01h | UTC
M-A | Safety and efficacy of tyrosine kinase inhibitors for the treatment of multiple sclerosis.
21 Oct, 2022 | 12:53h | UTC
M-A | Scalp block for postoperative pain after craniotomy.
21 Oct, 2022 | 12:51h | UTC
Crossover RCT | Spinal cord burst stimulation does not improve disability in chronic radicular pain after lumbar spine surgery.
19 Oct, 2022 | 14:29h | UTCEffect of Spinal Cord Burst Stimulation vs Placebo Stimulation on Disability in Patients With Chronic Radicular Pain After Lumbar Spine Surgery: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentary on Twitter
Among patients with chronic radicular pain after lumbar spine surgery, spinal cord burst stimulation, compared with placebo stimulation, resulted in no significant difference in back pain–related disability. https://t.co/XGiRRB4Njm #Research
— JAMA (@JAMA_current) October 18, 2022
Systematic Review | Antihistamines to prevent and treat motion sickness.
19 Oct, 2022 | 14:21h | UTCAntihistamines for motion sickness – Cochrane Library
Summary: Antihistamines to prevent and treat motion sickness – Cochrane Library
Commentary on Twitter
New from Cochrane Evidence: Antihistamines are likely to reduce the risk of developing motion sickness in susceptible adults under normal conditions, e.g. traveling by car or boat, but they may be more likely to cause drowsiness than placebo https://t.co/l3gtX9ad7T… pic.twitter.com/EcQZYmwMrU
— Cochrane ENT (@CochraneENT) October 17, 2022
Cohort Study | ARBs linked to decreased incidence of epilepsy compared with other antihypertensives.
19 Oct, 2022 | 14:18h | UTCAssociation Between Angiotensin Receptor Blocker Therapy and Incidence of Epilepsy in Patients With Hypertension – JAMA Neurology (free for a limited period)
Related:
Loneliness and health – Nature Reviews Disease Primers (if the link is paywalled, try this one)
The prevalence of loneliness across 113 countries: systematic review and meta-analysis – The BMJ
Social Isolation and Loneliness – World Health Organization
Psychological Distress and Loneliness Reported by US Adults in 2018 and April 2020 – JAMA
Cohort Study | Association of daily step count and intensity with incident dementia.
18 Oct, 2022 | 12:38h | UTCCommentaries:
Higher Step Counts Equal Better CV Health: UK Biobank – TCTMD
Related:
Cohort Study | Association of step counts over time with the risk of chronic diseases.
Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts.
M-A | Association of atrial septal aneurysm and shunt size with stroke recurrence and benefit from patent foramen ovale closure.
17 Oct, 2022 | 12:24h | UTCAssociation of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence and Benefit From Patent Foramen Ovale Closure – JAMA Neurology (free for a limited period)
Commentary: Anatomic Features Key for Selecting Patients Best Suited to PFO Closure – TCTMD
Commentary on Twitter
Patients with both large shunt and atrial septal aneurysm (ASA) benefit substantially more from patent foramen ovale than patients with large shunt alone, small shunt and ASA, or neither large shunt or ASA. https://t.co/lYL5sOnTCW #Research
— JAMA Neurology (@JAMANeuro) October 11, 2022
Cohort Study | Diagnostic yield of ECG-gated cardiac CT in the acute phase of ischemic stroke vs. transthoracic echocardiography.
17 Oct, 2022 | 12:23h | UTCDiagnostic Yield of ECG-Gated Cardiac CT in theAcute Phase of Ischemic Stroke vsTransthoracic Echocardiography – Neurology (link to abstract – $ for full-text)
Author Interview: ECG-Gated Cardiac CT in Acute Ischemic Stroke vs Transthoracic Echocardiography
Commentary: Add Cardiac CT to Acute Stroke Imaging to Detect Cardioembolism -Medscape (free registration required)
RCTs | Thrombectomy improved recovery in basilar artery stroke but increased procedural complications and hemorrhages.
14 Oct, 2022 | 14:20h | UTCStudy 1: Trial of Endovascular Treatment of Acute Basilar-Artery Occlusion – New England Journal of Medicine (link to abstract – $ for full-text)
Study 2: Trial of Thrombectomy 6 to 24 Hours after Stroke Due to Basilar-Artery Occlusion – New England Journal of Medicine (link to abstract – $ for full-text)
Related:
Commentary on Twitter
In 340 Chinese patients with basilar-artery occlusion, endovascular treatment resulted in better neurologic outcomes than medical care. Approximately one third of patients underwent intravenous thrombolysis. https://t.co/ZqHirYnjoH pic.twitter.com/fuRV3rFWX7
— NEJM (@NEJM) October 13, 2022
Cohort Study | Carotid plaque characteristics predict recurrent ischemic stroke and transient ischemic attack.
14 Oct, 2022 | 14:08h | UTC
RCT | Effect of exercise training or complex mental and social activities on cognitive function in adults with chronic stroke.
14 Oct, 2022 | 13:59h | UTCCommentary: For seniors who had a stroke and risk dementia, exercise can help, study says – UPI
See also: Visual Abstract
Review | Transient ischemic attack and minor stroke: diagnosis, risk stratification and management.
13 Oct, 2022 | 13:50h | UTC
Cohort Study | Migraine is linked to increased risk of subsequent Alzheimer’s and vascular dementia.
6 Oct, 2022 | 13:43h | UTCCommentary: Migraine May Increase Subsequent Dementia Risk – HealthDay
Retrospective cohort study | Neurodegenerative disease risk among former international rugby union players.
5 Oct, 2022 | 13:49h | UTCNews Release: Neurodegenerative disease risk doubled for former rugby players – BMJ Newsroom
Video summary: neurodegenerative disease risk among former international rugby union players
Related: Study shows unique diagnostic signatures of concussion in the saliva of Rugby players
The Lancet Commission | Traumatic brain injury: progress and challenges in prevention, clinical care, and research.
4 Oct, 2022 | 14:36h | UTCHomepage: Traumatic brain injury: progress and challenges in prevention, clinical care, and research (free registration required for all articles)
Traumatic brain injury advances since 2017: what has changed? – The Lancet Neurology
Consensus Recommendations | Diagnosis and management of patients with adrenoleukodystrophy.
4 Oct, 2022 | 14:35h | UTC
Commentary on Twitter (thread – click for more)
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(22)00447-8/fulltext
Brief review | Optimal sedation strategy for critically ill patients.
3 Oct, 2022 | 13:56h | UTC
Systematic Review | Repetitive peripheral magnetic stimulation after stroke – not enough evidence to guide recommendations.
3 Oct, 2022 | 13:45h | UTC
RCT | Induced hypothermia did not improve survival or functional outcomes after in-hospital cardiac arrest.
30 Sep, 2022 | 12:43h | UTCTemperature Control After In-Hospital Cardiac Arrest: A Randomized Clinical Trial – Circulation (free for a limited period)
Related:
Hypothermic versus Normothermic Temperature Control after Cardiac Arrest – NEJM Evidence
ERC-ESICM guidelines on temperature control after cardiac arrest in adults – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
New RCT of hypothermia (32-34°C) vs normothermia in IHCA 🧠❄️
👥 249 patients (25% shockable, 78% outside ICU/ED)
➡️ similar mortality at 180d (73% vs 71%)
➡️ similar favorable neuro outcome at 180d (23% vs 24%)🔗 @CircAHA https://t.co/1Axq8a5Wrn#ResusTwitter @thiele_holger pic.twitter.com/Jh69CHuUWZ
— Tommaso Scquizzato, MD (@tscquizzato) September 29, 2022
RCT | Effect of Dimethyl Fumarate vs. Interferon Beta-1a in patients with pediatric-onset multiple sclerosis.
29 Sep, 2022 | 13:29h | UTCInvited Commentary: Considering the Future of Pediatric Multiple Sclerosis Trials After the CONNECT Open-Label Randomized Trial – JAMA Network Open
See also: Visual Abstract
M-A of randomized trials | Regional anesthesia techniques and postoperative delirium.
28 Sep, 2022 | 13:48h | UTCRelated:
Autoimmune encephalitis: a physician’s guide to the clinical spectrum diagnosis and management.
28 Sep, 2022 | 13:37h | UTC