Neurology | Page 10 of 81 | Links Medicus Content Curation & Alerts in Medicine

RCT | Tenecteplase noninferior to alteplase in acute ischemic cerebrovascular events

13 Feb, 2023 | 12:59h | UTC

Tenecteplase versus alteplase in acute ischaemic cerebrovascular events (TRACE-2): a phase 3, multicentre, open-label, randomised controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)

RCTs | Endovascular therapy improves functional outcomes in large ischemic strokes, but increases bleeding and vascular complications

13 Feb, 2023 | 13:00h | UTC

Study 1: Trial of Endovascular Thrombectomy for Large Ischemic Strokes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Major international study finds thrombectomy highly effective treatment for large strokes – University Hospitals Cleveland Medical Center

Study 2: Trial of Endovascular Therapy for Acute Ischemic Stroke with Large Infarct – New England Journal of Medicine (link to abstract – $ for full-text)

M-A | Tenecteplase vs. alteplase for treatment of acute ischemic stroke

13 Feb, 2023 | 12:57h | UTC

Tenecteplase vs. alteplase for treatment of acute ischemic stroke: A systematic review and meta-analysis of randomized trials – Frontiers in Neurology

RCT | Argatroban plus Alteplase not better than Alteplase alone in patients with acute ischemic stroke

10 Feb, 2023 | 13:59h | UTC

Effect of Argatroban Plus Intravenous Alteplase vs Intravenous Alteplase Alone on Neurologic Function in Patients With Acute Ischemic Stroke: The ARAIS Randomized Clinical Trial – JAMA (free for a limited period)

Commentary on Twitter

Among patients with acute ischemic #stroke who received intravenous alteplase, argatroban was not significantly associated with better neurologic function. https://t.co/s9BDEvRvFA pic.twitter.com/HIRnGmiWMU

— JAMA (@JAMA_current) February 9, 2023

Consensus Paper | Use of cerebral CT angiography to support a clinical diagnosis of death using neurological criteria

10 Feb, 2023 | 13:48h | UTC

The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline – Anaesthesia

Guillain–Barré syndrome following influenza vaccination: a 15-year nationwide population-based case–control study

10 Feb, 2023 | 13:35h | UTC

Guillain–Barré syndrome following influenza vaccination: A 15-year nationwide population-based case–control study – European Journal of Neurology

Commentary: Influenza vaccination increases risk of Guillain-Barre syndrome within one month – Medical Dialogues

Sex differences in clinical features, treatment, and lifestyle factors in patients with cluster headache

10 Feb, 2023 | 13:33h | UTC

Sex Differences in Clinical Features, Treatment, and Lifestyle Factors in Patients With Cluster Headache – Neurology

Commentaries:

Differences ID’d Between Men, Women With Cluster Headache – HealthDay

Cluster Headaches Affect Men More Often, But It’s Women Who Are Hit Hardest – Science Alert

[Not published yet] Dual blood thinners under prescribed after minor or warning stroke, especially in women

9 Feb, 2023 | 14:01h | UTC

Dual blood thinners under prescribed after minor or warning stroke, especially in women – American Heart Association

Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke – The BMJ

Dual Antiplatelet Therapy Versus Aspirin in Patients With Stroke or Transient Ischemic Attack: Meta-Analysis of Randomized Controlled Trials – Stroke

Efficacy and Safety of Using Dual Versus Monotherapy Antiplatelet Agents in Secondary Stroke Prevention: Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials – Circulation

Multiple versus fewer antiplatelet agents for preventing early recurrence after ischaemic stroke or transient ischaemic attack – Cochrane Library

INCOG 2.0 Guidelines for cognitive rehabilitation following traumatic brain injury

9 Feb, 2023 | 13:47h | UTC

INCOG 2.0 Guidelines for Cognitive Rehabilitation Following Traumatic Brain Injury – The Journal of Head Trauma Rehabilitation

Commentary: Major update of the INCOG guidelines for cognitive rehabilitation following traumatic brain injury – News Medical

What’s Changed From 2014 to Now?

Methods, Overview, and Principles

Part I: Posttraumatic Amnesia

Part II: Attention and Information Processing Speed

Part III: Executive Functions

Part IV: Cognitive-Communication and Social Cognition Disorders

Part V: Memory

M-A | Comparative antiseizure medications for adjunctive treatment in children with drug-resistant focal-onset seizures

9 Feb, 2023 | 13:22h | UTC

Comparative antiseizure medications of adjunctive treatment for children with drug-resistant focal-onset seizures: A systematic review and network meta-analysis – Frontiers in Pharmacology

Guideline | Delirium: prevention, diagnosis and management in hospital and long-term care

7 Feb, 2023 | 14:21h | UTC

Delirium: prevention, diagnosis and management in hospital and long-term care – National Institute for Health and Care Excellence

SR | Cognitive stimulation to improve cognitive functioning in people with dementia

7 Feb, 2023 | 13:59h | UTC

Cognitive stimulation to improve cognitive functioning in people with dementia – Cochrane Library

Summary: Can cognitive stimulation benefit people with dementia? – Cochrane Library

Review | Cerebral multimodality monitoring in adult neurocritical care patients with acute brain injury

7 Feb, 2023 | 13:32h | UTC

Cerebral multimodality monitoring in adult neurocritical care patients with acute brain injury: A narrative review – Frontiers in Physiology

Detection of pro-ictal state in human temporal lobe epilepsy

6 Feb, 2023 | 13:16h | UTC

Pro-Ictal State in Human Temporal Lobe Epilepsy – NEJM Evidence

M-A | Efficacy and safety of dietary therapies for childhood drug-resistant epilepsy

6 Feb, 2023 | 13:00h | UTC

Efficacy and Safety of Dietary Therapies for Childhood Drug-Resistant Epilepsy: A Systematic Review and Network Meta-analysis – JAMA Pediatrics (link to abstract – $ for full-text)

RCT | Safety, efficacy, and tolerability of modified Atkins diet in persons with drug-resistant epilepsy

Efficacy of Ketogenic Diet, Modified Atkins Diet, and Low Glycemic Index Therapy Diet Among Children With Drug-Resistant Epilepsy: A Randomized Clinical Trial – JAMA Pediatrics

Commentary on Twitter

Modified Atkins diet may have better tolerability and higher probability of short-term seizure reduction than ketogenic diet. https://t.co/B416ypjUWr

— JAMA Pediatrics (@JAMAPediatrics) January 30, 2023

M-A | Types and concentrations of blood-based biomarkers in adults with peripheral neuropathies

3 Feb, 2023 | 13:49h | UTC

Types and Concentrations of Blood-Based Biomarkers in Adults With Peripheral Neuropathies: A Systematic Review and Meta-analysis – JAMA Network Open

Cohort Study | Association between antiepileptic drugs and incident Parkinson disease

3 Feb, 2023 | 13:51h | UTC

Association Between Antiepileptic Drugs and Incident Parkinson Disease in the UK Biobank – JAMA Neurology (link to abstract – $ for full-text)

Commentary on Twitter

This study using @uk_biobank data found evidence of an association between anti-epileptic drugs and incident #ParkinsonDisease. https://t.co/58PMlWQUYU

— JAMA Neurology (@JAMANeuro) December 28, 2022

M-A | Depressive symptoms in individuals with persistent postconcussion symptoms

3 Feb, 2023 | 13:48h | UTC

Depressive Symptoms in Individuals With Persistent Postconcussion Symptoms: A Systematic Review and Meta-Analysis – JAMA Network Open

Commentary: Significant Link Seen for Persistent Postconcussion Symptoms, Depression – HealthDay

Commentary on Twitter

Patients with persistent postconcussion symptoms are at increased risk of experiencing symptoms of depression. Post-injury support and interventions targeting mental health are necessary for optimal outcomes. https://t.co/7KiletIsf6

— JAMA Network Open (@JAMANetworkOpen) December 27, 2022

Cardiometabolic multimorbidity and incident dementia: the Swedish twin registry

3 Feb, 2023 | 13:45h | UTC

Cardiometabolic multimorbidity and incident dementia: the Swedish twin registry – European Heart Journal

Editorial: Deciphering dementia in the cardiometabolic continuum – European Heart Journal

Randomized Crossover Trial | Efficacy of a singing intervention on communication and psychosocial functioning in chronic aphasia

3 Feb, 2023 | 13:44h | UTC

Efficacy of a multicomponent singing intervention on communication and psychosocial functioning in chronic aphasia: a randomized controlled crossover trial – Brain Communications

News Release: Singing-based group rehabilitation can support communication and speech production of stroke patients – University of Helsinki/News Medical

Efficacy, safety, and tolerability of antidepressants for pain in adults: overview of systematic reviews

2 Feb, 2023 | 15:05h | UTC

Efficacy, safety, and tolerability of antidepressants for pain in adults: overview of systematic reviews – The BMJ

Editorial: Rethinking use of medicines for chronic pain – The BMJ

News Release: Antidepressants use for chronic pain on the rise, but are they effective? – University of Sidney

Commentary from the author on Twitter (thread – click for more)

Out today in @bmj_latest

We reviewed the evidence on the efficacy of antidepressants for pain in adults

We showed that antidepressants are effective for some pain conditions, but for most they are either ineffective or evidence is inconclusivehttps://t.co/E2XVQ9oGUQ
🧵 pic.twitter.com/kBo7eAyeCP

— Giovanni Ferreira (@giovanni_ef) February 1, 2023