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Nephrology

[Abstract Only] Study: Artificial Intelligence Algorithm can Predict the Development of Acute Kidney Injury

1 Aug, 2019 | 08:49h | UTC

A clinically applicable approach to continuous prediction of future acute kidney injury – Nature (link to abstract – $ for full-text)

Commentaries: DeepMind AI predicts acute loss of kidney function two days in advance, study shows – STAT (free) AND Deep learning detects impending organ injury in the clinic – Nature News (free) AND Expert reaction to study on a deep learning approach to predicting acute kidney injury – Science Media Centre (free)

 


Simulation Study: Uniform CT Imaging for Patients with Hematuria May Result in Increased Costs and Harms of Secondary Cancers

30 Jul, 2019 | 01:37h | UTC

Comparison of the Harms, Advantages, and Costs Associated With Alternative Guidelines for the Evaluation of Hematuria – JAMA Internal Medicine (free for a limited period)

Commentaries: Hematuria Practice Guidelines That Explicitly Consider Harms and Costs – JAMA Internal Medicine (free for a limited period) AND Evaluating Hematuria: Uniform Use of CT Seen as Risky and Expensive – NEJM Journal Watch (free)

 

Related Commentary on Twitter (Thread – Click for More)

 


Study: A Cardiovascular Risk-based Strategy for the Treatment of Hypertensive Patients Could Prevent More Cardiovascular Disease Events

28 Jul, 2019 | 23:08h | UTC

Eligibility and subsequent burden of cardiovascular disease of four strategies for blood pressure-lowering treatment: a retrospective cohort study – The Lancet (free)

Commentaries: Strategies to identify patients for antihypertensive treatment – The Lancet (free) AND Using cardiovascular risk to identify patients eligible for blood pressure treatment could prevent significantly more heart attacks and strokes – London School of Hygiene & Tropical Medicine (free) AND Expert reaction to paper on identifying those eligible for blood pressure treatment and subsequent burden of cardiovascular disease – Science Media Centre (free)

 

Related Commentary on Twitter

 


[Abstracts Only] Randomized Trials: Evaluation of New Treatment for Anemia of Chronic Kidney

27 Jul, 2019 | 13:55h | UTC

Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis – New England Journal of Medicine (link to abstract – $ for full-text)

Related Study: Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis- New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Roxadustat Effective in Correcting Anemia in Nondialysis CKD and Dialysis – Renal & Urology News (free) AND New Oral Agent for Anemia in CKD Encouraging but Questions Remain – Medscape (free registration required)

 


Meta-Analysis: Impact of Furosemide on Mortality and the Requirement for Renal Replacement Therapy in Acute Kidney Injury

26 Jul, 2019 | 00:45h | UTC

Impact of furosemide on mortality and the requirement for renal replacement therapy in acute kidney injury: a systematic review and meta-analysis of randomised trials – Annals of Intensive Care (free)

 


Review: Renal Replacement Therapy in the Critical Care Setting

25 Jul, 2019 | 01:51h | UTC

Renal Replacement Therapy in the Critical Care Setting – Critical Care Research and Practice (free)

Related Meta-Analysis: Early Initiation of Renal Replacement Therapy in Critically Ill Patients (free)

Related Randomized Trial: Early vs. Delayed Dialysis in Acute Kidney Injury (link to abstract and commentaries)

Source: Critical Care Reviews Newsletter

 


Guideline on Peri- and Postoperative Care of Arteriovenous Fistulas and Grafts for Hemodialysis in Adults

23 Jul, 2019 | 01:58h | UTC

Clinical practice guideline on peri- and postoperative care of arteriovenous fistulas and grafts for haemodialysis in adults – Nephrology Dialysis Transplantation (free)

 


[Abstract Only] Pilot Study Suggests High-dose Spironolactone May Be Effective in Diuretic-Resistant Heart Failure

21 Jul, 2019 | 20:47h | UTC

High-Dose Spironolactone When Patients With Acute Decompensated Heart Failure Are Resistant to Loop Diuretics: A Pilot Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: High-Dose Spironolactone Effective in Diuretic-Resistant Heart Failure – NEJM Journal Watch (free)

 


Cochrane Review: Buffered Solutions Do Not Improve Mortality in Critically Ill Adults and Children Compared to 0,9% Saline

20 Jul, 2019 | 18:35h | UTC

Buffered solutions versus 0.9% saline for resuscitation in critically ill adults and children – Cochrane Library (free)

Summary: Buffered solutions versus 0.9% saline for resuscitation in critically ill adults and children – Cochrane Library (free)

Related Meta-Analysis: Choice of Intravenous Crystalloid Fluid and Mortality in Critically Ill Adult Patients – Southern Medical Journal (link to abstract – $ for full-text)

Related Randomized Trials: Balanced Crystalloids vs Saline in Hospitalized Patients (free studies and commentary)

“The three ongoing studies once published and assessed may alter the conclusions of the review.”

 


[Abstract Only] Meta-Analysis: Benefits and Harms of Oral Anticoagulant Therapy in Chronic Kidney Disease

16 Jul, 2019 | 09:43h | UTC

Benefits and Harms of Oral Anticoagulant Therapy in Chronic Kidney Disease: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Non-vitamin K oral anticoagulants appear superior to vitamin K antagonists in early-stage CKD – ACP Internist (free) AND Evidence Favors NOACs for Anticoagulation in Early Chronic Kidney Disease – NEJM Journal Watch (free)

 


Meta-analysis: Hemodynamic Goal-directed Therapy and Postoperative Kidney Injury

16 Jul, 2019 | 09:21h | UTC

Hemodynamic goal-directed therapy and postoperative kidney injury: an updated meta-analysis with trial sequential analysis – Critical Care (free)

 


[Abstract Only] Meta-Analysis: Balanced Crystalloids Do Not Improve Outcomes When Compared with Normal Saline in Critically Ill Patients

14 Jul, 2019 | 19:13h | UTC

Choice of Intravenous Crystalloid Fluid and Mortality in Critically Ill Adult Patients – Southern Medical Journal (link to abstract – $ for full-text)

Related Randomized Trials: Balanced Crystalloids vs Saline in Hospitalized Patients (free studies and commentary)

Source: Hospital Medicine Virtual Journal Club

 


Consensus Statement on Renal Denervation

14 Jul, 2019 | 19:00h | UTC

Joint UK societies’ 2019 consensus statement on renal denervation – Heart (free)

 


Quality Improvement Goals for Acute Kidney Injury

11 Jul, 2019 | 10:15h | UTC

Quality Improvement Goals for Acute Kidney Injury – Clinical Journal of the American Society of Nephrology (free)

 

Related Commentary on Twitter

 


[Abstract Only] Study: Directly Observed Therapy May Identify Nonadherence in Patients with Apparent Treatment-Resistant Hypertension

8 Jul, 2019 | 10:03h | UTC

Use of Directly Observed Therapy to Assess Treatment Adherence in Patients With Apparent Treatment-Resistant Hypertension – JAMA Internal Medicine (free link for a limited period)

Commentaries: Directly Observed Therapy Effective for Treatment-Resistant Hypertension – Clinical Advisor (free) AND Think it’s treatment-resistant hypertension? Your eyes need to DOT (directly observe therapy) – Univadis (free registration required)

 

Related Commentary on Twitter

 


Hypertension in CKD: Core Curriculum 2019

5 Jul, 2019 | 02:38h | UTC

Hypertension in CKD: Core Curriculum 2019 – American Journal of Kidney Diseases (free) (via @Abraham_RMI)

Related: KDOQI US Commentary on the 2017 ACC/AHA Hypertension Guideline – American Journal of Kidney Diseases (free)

 


[Abstract Only] Randomized Trial: Treatments for Membranous Nephropathy Compared

4 Jul, 2019 | 11:09h | UTC

Rituximab or Cyclosporine in the Treatment of Membranous Nephropathy – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Study Finds Rituximab Noninferior to Cyclosporine for Membranous Nephropathy – Center for Biosimilars (free)

 


Cohort Study: Association of Initiation of Maintenance Dialysis with Functional Status and Caregiver Burden

4 Jul, 2019 | 10:40h | UTC

Association of Initiation of Maintenance Dialysis with Functional Status and Caregiver Burden – Clinical Journal of the American Society of Nephrology (free)

Commentaries: Functional Decline Seen in Many Older Adults Initiating Dialysis – Renal & Urology News (free) AND Many Older Patients Initiating Dialysis Experience Functional Decline – American Society of Nephrology (free) AND Starting Dialysis Worse Than ‘Being Hit by a Silent Freight Train’ – Medscape (free registration required)

 


Portuguese Guidelines in Peritoneal Dialysis

3 Jul, 2019 | 06:01h | UTC

Current guidelines in peritoneal dialysis – Part I – Portuguese Journal of Nephrology & Hypertension (free PDF)

Part II: Current guidelines in peritoneal dialysis (free PDF)

 


Estimation of Kidney Function in Oncology

30 Jun, 2019 | 17:47h | UTC

Estimation of Kidney Function in Oncology: Implications for Anticancer Drug Selection and Dosing – Clinical Journal of the American Society of Nephrology (free)

“In one retrospective study, approximately one half of kidney function–impaired patients with solid tumors who were receiving a drug that necessitated dose adjustments for kidney function received almost 50% of their prescriptions at standard doses”.

 


[Abstract Only] Cohort Study: Kidney Donors with Hypertension Have a Higher Risk of Kidney Failure

26 Jun, 2019 | 00:39h | UTC

Risk of ESKD in Older Live Kidney Donors with Hypertension – Clinical Journal of the American Society of Nephrology (link to abstract – $ for full-text)

Commentary: Higher Risk of Kidney Failure in Older Donors With Hypertension – Medscape (free registration required)

 

Related Commentary on Twitter

 


Physiology and Pathophysiology of Potassium Homeostasis

25 Jun, 2019 | 06:31h | UTC

Physiology and Pathophysiology of Potassium Homeostasis: Core Curriculum 2019 – American Journal of Kidney Diseases (free)

 


Meta-analysis: Effects of Treatment of Metabolic Acidosis in CKD

24 Jun, 2019 | 01:06h | UTC

Effects of Treatment of Metabolic Acidosis in CKD: A Systematic Review and Meta-Analysis – Clinical Journal of the American Society of Nephrology (free)

Related: Sodium Bicarbonate for Metabolic Acidosis Slows CKD Progression – Renal & Urology News (free)

 


Metabolic Acidosis in CKD: Core Curriculum 2019

24 Jun, 2019 | 01:05h | UTC

Metabolic Acidosis in CKD: Core Curriculum 2019 – American Journal of Kidney Diseases (free)

 


[Abstract Only] Randomized Trial: In Patients Undergoing Cardiac Surgery, A Restrictive Transfusion Approach Does Not Increase the Risk of Acute Kidney Injury

21 Jun, 2019 | 08:15h | UTC

Safety of a Restrictive versus Liberal Approach to Red Blood Cell Transfusion on the Outcome of AKI in Patients Undergoing Cardiac Surgery: A Randomized Clinical Trial – Journal of the American Society of Nephrology (link to abstract – $ for full-text)

Commentary: Restrictive Approach to Blood Cell Transfusions Safe for Heart Surgery Patients – American Society of Nephrology (free)

Related: Effects of restrictive red blood cell transfusion on the prognoses of adult patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials – Critical Care (free) AND Research: Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery (free study and commentaries) AND Transfusion Requirements After Cardiac Surgery: The TRACS Randomized Controlled Trial – JAMA (free)

 


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