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Nephrology

Organ transplant recipients remain vulnerable to Covid-19 even after second vaccine dose.

6 May, 2021 | 09:03h | UTC

Organ Transplant Recipients Remain Vulnerable to Covid-19 Even After Second Vaccine Dose – Johns Hopkins Medicine

Original Study: Antibody Response to 2-Dose SARS-CoV-2 mRNA Vaccine Series in Solid Organ Transplant Recipients – JAMA

 

M-A: Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease – “a 5 mm Hg reduction of systolic BP reduced the risk of major CV events by about 10%, irrespective of previous diagnoses of CV disease, and even at normal or high–normal BP values”

3 May, 2021 | 05:29h | UTC

Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis – The Lancet

Commentaries: Many more people could benefit from blood pressure-lowering medication – The Lancet AND Decisions about antihypertensive treatment should focus on reducing cardiovascular risk – The Lancet

 

AHA Statement: Management of Stage 1 Hypertension in Adults With a Low 10-Year Risk for Cardiovascular Disease – “There is a lack of randomized clinical trials that have evaluated CVD outcomes among individuals with stage 1 hypertension and a low 10-year ASCVD risk”

30 Apr, 2021 | 08:37h | UTC

Management of Stage 1 Hypertension in Adults With a Low 10-Year Risk for Cardiovascular Disease: Filling a Guidance Gap: A Scientific Statement From the American Heart Association – Hypertension

News Release: If slightly high blood pressure doesn’t respond to lifestyle change, medication can help – American Heart Association

Top Things to Know: Management of Stage 1 Hypertension in Adults With a Low 10-Year Risk for Cardiovascular Disease – American Heart Association

Commentary: The Hypertension Pandemic: Need for a Strategic Evidence-based Response – American Heart Association

 

RCT: Reduced dose direct oral anticoagulants may be a safer option to vitamin K antagonists in hemodialysis patients with atrial fibrillation

27 Apr, 2021 | 09:27h | UTC

Safety and Efficacy of Vitamin K Antagonists versus Rivaroxaban in Hemodialysis Patients with Atrial Fibrillation: A Multicenter Randomized Controlled Trial – Journal of the American Society of Nephrology (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Do you really need to drink 8 glasses of water a day? An exercise scientist explains why your kidneys say ‘no’

23 Apr, 2021 | 08:11h | UTC

Do you really need to drink 8 glasses of water a day? An exercise scientist explains why your kidneys say ‘no’ – The Conversation

 

Outcome of acute kidney injury: how to make a difference?

20 Apr, 2021 | 05:26h | UTC

Outcome of acute kidney injury: how to make a difference? – Annals of Intensive Care

 

Hemodialysis Emergencies: Core Curriculum 2021

16 Apr, 2021 | 06:13h | UTC

Hemodialysis Emergencies: Core Curriculum 2021 – American Journal of Kidney Diseases

 

Commentary on Twitter

 

Cohort study: Higher cumulative exposure to Thiazide diuretics linked to an increased risk of skin cancer in people older than 65 years

13 Apr, 2021 | 05:08h | UTC

Association between antihypertensive medications and risk of skin cancer in people older than 65 years: a population-based study – Canadian Medical Association Journal

Commentaries: Thiazides May Up Risk for Skin Cancer in Older Adults – HealthDay AND Some blood pressure medication linked to higher risk of skin cancer, study finds – CTV News

Related study: Case-Control Study: Possible Association of Hydrochlorothiazide Use and Risk of Melanoma

 

Another study shows intravenous radiocontrast use is not associated with reduced kidney function

12 Apr, 2021 | 00:44h | UTC

Association of Intravenous Radiocontrast With Kidney Function: A Regression Discontinuity Analysis – JAMA Internal Medicine

Commentaries: Radiocontrast Exposure Safe for Kidney Function – HCP Live AND Exposure to contrast on CTPA doesn’t cause long-term kidney injury – AuntMinnie

Related: ACR/NKF Consensus Statement: “The Risk of Acute Kidney Injury Developing in Patients with Reduced Kidney Function Following Exposure to Intravenous Iodinated Contrast Media has Been Overstated” (Guideline and commentaries)

 

Commentary on Twitter (thread – click for more)

 

Diagnostic Test Interpretation: Evaluation of Hypokalemia

6 Apr, 2021 | 01:07h | UTC

Evaluation of Hypokalemia – JAMA (free for a limited period)

 

RCT: Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1

5 Apr, 2021 | 01:01h | UTC

Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1 – New England Journal of Medicine (link to abstract – $ for full-text)

 

RCT: Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury – waiting too long can be deleterious

2 Apr, 2021 | 09:17h | UTC

Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury (AKIKI 2): a multicentre, open-label, randomised, controlled trial – The Lancet (link to abstract – $ for full-text)

 

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

1 Apr, 2021 | 03:32h | UTC

Effects of a reduced-sodium added-potassium salt substitute on blood pressure in rural Indian hypertensive patients: a randomized, double-blind, controlled trial – American Journal of Clinical Nutrition

Commentary: Salt substitution — an effective way to reduce blood pressure in rural India – The George Institute for Global Health

 

Commentaries on Twitter

https://twitter.com/Dr_WuJ/status/1376715405553590275

 

Review: Use of urine electrolytes and urine osmolality in the clinical diagnosis of fluid, electrolytes, and acid-base disorders

25 Mar, 2021 | 08:06h | UTC

Use of Urine Electrolytes and Urine Osmolality in the Clinical Diagnosis of Fluid, Electrolytes, and Acid-Base Disorders – KI Reports

 

Commentary on Twitter

 

Perspective | Prioritizing peritoneal catheter placement during the COVID-19 pandemic

16 Mar, 2021 | 02:16h | UTC

Prioritizing Peritoneal Catheter Placement during the COVID-19 Pandemic: A Perspective of the American Society of Nephrology COVID-19 Home Dialysis Subcommittee – Clinical Journal of the American Society of Nephrology

 

Commentary on Twitter

 

Editorial: How I prescribe continuous renal replacement therapy

16 Mar, 2021 | 01:27h | UTC

How I prescribe continuous renal replacement therapy – Critical Care

 

Managing Patients with Failing Kidney Allograft: Many Questions Remain

12 Mar, 2021 | 08:06h | UTC

Managing Patients with Failing Kidney Allograft: Many Questions Remain – Clinical Journal of the American Society of Nephrology

 

Study: Balanced crystalloids vs. saline in critically ill adults with hyperkalemia or acute kidney injury

9 Mar, 2021 | 02:05h | UTC

Can We Use LR for Hyperkalemia? – Journal Feed

Original study: Balanced Crystalloids versus Saline in Critically Ill Adults with Hyperkalemia or Acute Kidney Injury: Secondary Analysis of a Clinical Trial – American Journal of Respiratory and Critical Care Medicine

 

RCT: Mixed findings with Terlipressin plus Albumin for the treatment of Type 1 hepatorenal syndrome

4 Mar, 2021 | 08:35h | UTC

Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)

 

RCT: Albumin provides no benefit to hospitalized patients with decompensated cirrhosis

4 Mar, 2021 | 08:37h | UTC

A Randomized Trial of Albumin Infusions in Hospitalized Patients with Cirrhosis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Albumin provides no benefit to hospitalized patients with advanced liver disease – University College London

 

Management of congenital nephrotic syndrome: consensus recommendations of the ERKNet-ESPN Working Group

4 Mar, 2021 | 08:13h | UTC

Management of congenital nephrotic syndrome: consensus recommendations of the ERKNet-ESPN Working Group – Nature Reviews Nephrology

 

Systematic review: Aldosterone antagonists for people with chronic kidney disease requiring dialysis

3 Mar, 2021 | 08:27h | UTC

Aldosterone antagonists for people with chronic kidney disease requiring dialysis – Cochrane Library

 

Systematic review: Walking for hypertension

2 Mar, 2021 | 01:14h | UTC

Walking for hypertension – Cochrane Library

Summary: The effect of walking on blood pressure control – Cochrane Library

 

M-A: Adjuvant corticosteroids are effective in lowering the risk of kidney scarring in children with acute pyelonephritis

28 Feb, 2021 | 20:38h | UTC

Adjuvant corticosteroids for prevention of kidney scarring in children with acute pyelonephritis: a systematic review and meta-analysis – Archives of Disease in Childhood (link to abstract – $ for full-text)

 

ICU-based renal replacement therapy

25 Feb, 2021 | 08:23h | UTC

ICU-Based Renal Replacement Therapy – Critical Care Medicine

 

Commentary on Twitter

 

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