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Nephrology

M-A: Incidence and Relapse of Idiopathic Nephrotic Syndrome.

7 Jul, 2021 | 08:37h | UTC

Incidence and Relapse of Idiopathic Nephrotic Syndrome: Meta-analysis – Pediatrics (link to abstract – $ for full-text)

 

Acute kidney injury in the critically ill: an updated review on pathophysiology and management.

5 Jul, 2021 | 01:49h | UTC

Acute kidney injury in the critically ill: an updated review on pathophysiology and management – Intensive Care Medicine

 

Commentary on Twitter

 

Podcast | Evaluation and management of hypercalcemia.

29 Jun, 2021 | 09:51h | UTC

#281 Hypercalcemia: Calci-fun! with Dr. Carl Pallais – The Curbsiders

 

RCT: Similar outcomes with mycophenolate mofetil vs. azathioprine in kidney transplant recipients on steroid-free, low-dose cyclosporine immunosuppression.

29 Jun, 2021 | 09:50h | UTC

Mycophenolate mofetil versus azathioprine in kidney transplant recipients on steroid-free, low-dose cyclosporine immunosuppression (ATHENA): A pragmatic randomized trial – PLOS One

 

Guideline synopsis: management of blood pressure in patients with chronic kidney disease not receiving dialysis.

22 Jun, 2021 | 10:00h | UTC

Management of Blood Pressure in Patients With Chronic Kidney Disease Not Receiving Dialysis: Synopsis of the 2021 KDIGO Clinical Practice Guideline – Annals of Internal Medicine

Original guideline: KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease

Commentary: Guideline issued on blood pressure management in CKD – ACP Internist

 

M-A: Among patients with kidney failure treated with dialysis, mineralocorticoid receptor antagonists reduce cardiovascular and all-cause mortality without increasing the risk of hyperkalemia.

15 Jun, 2021 | 08:53h | UTC

Efficacy and Safety of Mineralocorticoid Receptor Antagonists in Kidney Failure Patients Treated with Dialysis: A Systematic Review and Meta-Analysis – Clinical Journal of the American Society of Nephrology (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Extracorporeal treatment for poisoning to beta-adrenergic antagonists: systematic review and recommendations from the EXTRIP workgroup.

14 Jun, 2021 | 08:27h | UTC

Extracorporeal treatment for poisoning to beta-adrenergic antagonists: systematic review and recommendations from the EXTRIP workgroup – Critical Care

 

The furosemide stress test: current use and future potential.

11 Jun, 2021 | 08:12h | UTC

The furosemide stress test: current use and future potential – Renal Failure

 

Cohort study: the use of potentially inappropriate medications in adults with chronic kidney disease is common and linked to increased risk of hospitalization, mortality, and falls.

11 Jun, 2021 | 08:11h | UTC

Risk of Potentially Inappropriate Medications in Adults With CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study – American Journal of Kidney Diseases (link to abstract – $ for full-text)

 

Commentary on Twitter

 

ANCA-Associated Vasculitis: An Update.

4 Jun, 2021 | 10:23h | UTC

ANCA-Associated Vasculitis: An Update – Journal of Clinical Medicine

 

RCT: Among patients with ANCA-associated vasculitis without severe glomerulonephritis or alveolar hemorrhage treated with Rituximab, a reduced-dose glucocorticoids regimen (prednisolone 0.5 mg/kg/d) was noninferior to a high-dose glucocorticoid regimen (prednisolone 1 mg/kg/d) for the induction of disease remission.

4 Jun, 2021 | 10:25h | UTC

Effect of Reduced-Dose vs High-Dose Glucocorticoids Added to Rituximab on Remission Induction in ANCA-Associated Vasculitis: A Randomized Clinical Trial – JAMA

 

Diagnosis and management of diabetes insipidus for the internist: an update

4 Jun, 2021 | 10:22h | UTC

Diagnosis and management of diabetes insipidus for the internist: an update – Journal of Internal Medicine

 

Consensus report: Postoperative acute kidney injury in adult non-cardiac surgery.

25 May, 2021 | 08:34h | UTC

Postoperative acute kidney injury in adult non-cardiac surgery: joint consensus report of the Acute Disease Quality Initiative and PeriOperative Quality Initiative – Nature Reviews Nephrology

Related review: The incidence, risk, presentation, pathophysiology, treatment, and effects of perioperative acute kidney injury – Canadian Journal of Anesthesiology

 

#ACC21 – RCT: Among patients with resistant hypertension, ultrasound renal denervation resulted in a modest improvement in systolic BP (–4.5 mm Hg) vs. sham procedure.

24 May, 2021 | 08:28h | UTC

Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Renal Denervation for Resistant Hypertension Is Not Back on Track – “A systolic blood pressure (SBP) reduction of 4.5 mm Hg is not good enough—for an invasive procedure”. – Medscape (free registration required)

 

SPRINT Trial final report: targeting a systolic BP of less than 120 mm Hg in patients at increased CV risk is associated with improved CV and mortality outcomes but increases the risk of serious adverse events.

20 May, 2021 | 08:36h | UTC

Final Report of a Trial of Intensive versus Standard Blood-Pressure Control – New England Journal of Medicine

Commentary: Final results of SPRINT study confirm controlling blood pressure critically important in preventing heart disease and stroke – Cleveland Medical Center

 

ESC Comprehensive review: Update on management of hypokalemia and goals for the lower potassium level in patients with cardiovascular disease.

20 May, 2021 | 08:26h | UTC

Update on management of hypokalemia and goals for the lower potassium level in patients with cardiovascular disease: A review in collaboration with the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy – European Heart Journal – Cardiovascular Pharmacotherapy

 

Commentary on Twitter

 

Fluid-induced harm in the hospital: look beyond volume and start considering sodium. From physiology towards recommendations for daily practice in hospitalized adults.

19 May, 2021 | 08:32h | UTC

Fluid-induced harm in the hospital: look beyond volume and start considering sodium. From physiology towards recommendations for daily practice in hospitalized adults – Annals of Intensive Care

 

Series: Social determinants of health in people with kidney disease.

19 May, 2021 | 08:29h | UTC

Introduction: Social Determinants of Health in People with Kidney Disease

The Pathogenesis of Race and Ethnic Disparities

Social Determinants of Kidney Health

Reducing the Burden of CKD among Latinx

The Seen and the Unseen: Race and Social Inequities Affecting Kidney Care

Personal Experiences of Patients in the Interaction of Culture and Kidney Disease

 

Commentary on Twitter

 

Large cohort study confirms the renal toxicities of anti-inflammatories, suggesting Ibuprofen may be the safest option among them.

19 May, 2021 | 08:28h | UTC

Comparative Risks of Nonsteroidal Anti-Inflammatory Drugs on CKD – Clinical Journal of the American Society of Nephrology (link to abstract – $ for full-text)

Commentary: Study: Ibuprofen Found Safest NSAID for the Kidney – MPR

 

Commentary on Twitter

 

AHA Scientific Statement: Evaluation and management of aortic stenosis in chronic kidney disease.

14 May, 2021 | 08:27h | UTC

Evaluation and Management of Aortic Stenosis in Chronic Kidney Disease: A Scientific Statement From the American Heart Association – Circulation

 

Review: The incidence, risk, presentation, pathophysiology, treatment, and effects of perioperative acute kidney injury.

12 May, 2021 | 08:27h | UTC

The incidence, risk, presentation, pathophysiology, treatment, and effects of perioperative acute kidney injury – Canadian Journal of Anesthesiology

 

A restrictive fluid management strategy shows promise for acute kidney injury in a pilot randomized controlled trial.

10 May, 2021 | 00:57h | UTC

Restrictive fluid management versus usual care in acute kidney injury (REVERSE-AKI): a pilot randomized controlled feasibility trial – Intensive Care Medicine

 

Commentary on Twitter

 

[#ACC21 – not published yet] 1 in 5 adults with high blood pressure also take a medicine that could be elevating their blood pressure.

10 May, 2021 | 00:58h | UTC

Have high blood pressure? You may want to check your meds – American College of Cardiology

Commentary: Are You Taking a Med That’s Raising Your Blood Pressure? – HealthDay

 

RCT: Efficacy and safety of voclosporin for lupus nephritis – voclosporin + MMF + low dose corticosteroids achieved complete renal response at week 52 more often than MMF + low dose corticosteroids alone (41% vs. 23%).

10 May, 2021 | 00:48h | UTC

Efficacy and safety of voclosporin versus placebo for lupus nephritis (AURORA 1): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)

 

Cohort study shows inadequate antibody response to mRNA SARS-CoV-2 vaccine among kidney transplant recipients.

6 May, 2021 | 09:01h | UTC

Antibody response to mRNA SARS-CoV-2 vaccine among kidney transplant recipients – Prospective cohort study – Clinical Microbiology and Infection

 

Commentary on Twitter

https://twitter.com/hildabast/status/1390097665451462656

 

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