Internal Medicine
M-A | Fluid resuscitation with balanced crystalloids vs. normal saline in critically ill patients.
11 Jul, 2022 | 12:00h | UTCRelated:
Back to BaSICS – Annals of Emergency Medicine
The ongoing saga of normal saline versus balanced fluids – First10EM
Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults – New England Journal of Medicine (link to abstract – $ for full-text)
RCT | Neutralizing COVID-19 convalescent plasma does not benefit adults hospitalized with COVID-19.
8 Jul, 2022 | 11:59h | UTC
BSG guidelines on the management of functional dyspepsia.
8 Jul, 2022 | 12:03h | UTCBritish Society of Gastroenterology guidelines on the management of functional dyspepsia – Gut
Related:
Interim Analysis | Oral Sabizabulin for high-risk, hospitalized adults with Covid-19.
8 Jul, 2022 | 12:02h | UTCOral Sabizabulin for High-Risk, Hospitalized Adults with Covid-19: Interim Analysis – NEJM Evidence
M-A | Associations of thiazide use with skin cancers.
8 Jul, 2022 | 11:55h | UTCAssociations of thiazide use with skin cancers: a systematic review and meta-analysis – BMC Medicine
Related:
Association of Hydrochlorothiazide Use and Risk of Malignant Melanoma – JAMA Internal Medicine
Consensus statements on the diagnosis and management of obstructive sleep apnea in patients with cardiovascular disease.
8 Jul, 2022 | 11:51h | UTC
RCT | Sacral neuromodulation for neurogenic lower urinary tract dysfunction.
8 Jul, 2022 | 11:47h | UTCSacral Neuromodulation for Neurogenic Lower Urinary Tract Dysfunction – NEJM Evidence
Commentary on Twitter
Pts with neurogenic lower urinary tract dysfunction had sacral neuromodulators implanted and optimized. They were then randomized to have the device either remain ON or switched OFF for 2 months. The success rate was 76% in the ON group vs 42% in the OFF. https://t.co/dhteW70jXp pic.twitter.com/1c0w8HOMJm
— NEJM Evidence (@NEJMEvidence) July 7, 2022
RCT | Effect of electroacupuncture on insomnia in patients with depression.
8 Jul, 2022 | 11:45h | UTCInvited Commentary: Effects of Electroacupuncture for Depression-Related Insomnia – JAMA Network Open
Commentary on Twitter
This randomized clinical trial found that an 8-weeek electroacupuncture with standard care improved sleep quality for patients with insomnia and depression, compared with sham acupuncture and/or standard care. https://t.co/nacnxEI4Ik
— JAMA Network Open (@JAMANetworkOpen) July 7, 2022
Egg and dietary cholesterol intake and risk of all-cause, cardiovascular, and cancer mortality: a systematic review and dose-response meta-analysis of prospective cohort studies.
8 Jul, 2022 | 11:23h | UTC
Review | Sickle cell disease.
7 Jul, 2022 | 12:59h | UTCSickle Cell Disease: A Review – JAMA (free for a limited period)
Audio Clinical Review: Sickle Cell Disease – JAMA
Test-negative, case–control study | Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada.
7 Jul, 2022 | 13:00h | UTC
Retrospective Cohort Study | Racial bias and reproducibility in pulse oximetry among medical and surgical inpatients.
7 Jul, 2022 | 12:57h | UTCNews Release: Pulse oximeters missed low oxygen levels in more Black veterans than white veterans – University of Michigan
Related:
Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine
FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT
Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration
Commentary on Twitter
New research found that for individuals in general (medical and surgical) care in hospital, occult hypoxemia was more common for black patients than for white patients https://t.co/DrNlaIE7ho
— The BMJ (@bmj_latest) July 6, 2022
Last Month in Nephrology – June 2022.
7 Jul, 2022 | 12:53h | UTCLast Month in Nephrology – June 2022
Commentary on Twitter
Want to review the practice changing literature published last month in nephrology in a few minutes?
Checkout our latest edition of #LastmonthinNephhttps://t.co/7pkokVEHlz pic.twitter.com/z158MCWuLv
— LastMonthinNeph (@LastNeph) July 6, 2022
M-A | It is not safe to withhold antibiotic use in uncomplicated urinary tract infections in adult women.
7 Jul, 2022 | 12:47h | UTC
Commentary on Twitter (thread – click for more)
A really important analysis of previous trials!
1/ All short-term outcomes were worse for women given non-antibiotic strategies, including need for future antibiotics (number needed to harm=5!) https://t.co/iozelljFLk
— Annie Joseph (@ajosephnotts) July 2, 2022
Post-hoc analysis | Can SGLT2 inhibitors reduce the risk of nephrolithiasis?
7 Jul, 2022 | 12:42h | UTC
Tricuspid regurgitation: recent advances in understanding pathophysiology, severity grading and outcome.
7 Jul, 2022 | 12:38h | UTC
Post-hoc analysis | Can SGLT2 inhibitors reduce the risk of hyperuricemia and gout?
7 Jul, 2022 | 12:40h | UTC
Registry-based cohort study | Association between gout and cardiovascular outcomes in adults with no history of cardiovascular disease.
7 Jul, 2022 | 12:32h | UTC
Commentary on Twitter
https://twitter.com/BMJMedicine/status/1544400223916724226
Podcast | Headache update: making migraines less painful.
7 Jul, 2022 | 12:24h | UTC#341: Headache Update: Making Migraines Less Painful with Dr. Kevin Weber – The Curbsiders
Review | Tuberculosis in cirrhosis – A diagnostic and management conundrum.
7 Jul, 2022 | 12:18h | UTC
M-A | DOACs vs. VKAs in atrial fibrillation patients with bioprosthetic heart valve.
7 Jul, 2022 | 12:15h | UTC
Cohort Study | Association of the “weekend warrior” and other leisure-time physical activity patterns with all-cause and cause-specific mortality.
6 Jul, 2022 | 11:53h | UTCAssociation of the “Weekend Warrior” and Other Leisure-time Physical Activity Patterns With All-Cause and Cause-Specific Mortality: A Nationwide Cohort Study – JAMA Internal Medicine (free for a limited period)
RCT | High-dose dexamethasone and oxygen support strategies in intensive care unit patients with severe COVID-19 acute hypoxemic respiratory failure.
6 Jul, 2022 | 11:51h | UTC
Commentary on Twitter
In this RCT, high-dose dexamethasone did not significantly improve the 60-day survival. The oxygenation strategy in initially non-intubated patients did not significantly modify the 28-day risk of invasive mechanical ventilation requirement. https://t.co/ZNajW2KBKR
— JAMA Internal Medicine (@JAMAInternalMed) July 5, 2022
FDA orders Juul to remove all its e-cigarettes from US market.
6 Jul, 2022 | 11:46h | UTCFDA orders Juul to remove all its e-cigarettes from US market – The BMJ
See also:
FDA orders all Juul e-cigarettes off the market – POLITICO
The FDA orders Juul to pull all of its vaping products from the U.S. market – NPR
FDA orders Juul Labs to remove products from US market – CNN
FDA News Release: FDA Denies Authorization to Market JUUL Products – U.S. Food & Drug Administration