Internal Medicine | Page 62 of 487 | Links Medicus Content Curation & Alerts in Medicine

Perspective | Push to use antibiotics to prevent sexually transmitted infections raises concerns.

2 Dec, 2022 | 14:27h | UTC

Push to use antibiotics to prevent sexually transmitted infections raises concerns – Nature

M-A | Risk of hypovolemia associated with sodium–glucose cotransporter-2 inhibitors treatment.

2 Dec, 2022 | 14:31h | UTC

Risk of hypovolemia associated with sodium–glucose cotransporter-2 inhibitors treatment: A meta-analysis of randomized controlled trials – Frontiers in Cardiovascular Medicine

M-A | Association between the FRAIL Scale and postoperative complications in older surgical patients.

2 Dec, 2022 | 14:21h | UTC

Association Between the FRAIL Scale and Postoperative Complications in Older Surgical Patients: A Systematic Review and Meta-Analysis – Anesthesia & Analgesia

Commentary on Twitter

Study showing FRAIL scale association with 30-d & 6 mo mortality, postop complications, & delirium.Odds ratios are nice but actual% may be more helpful.If OR is 3 but % complications is 0.5%, it’s not that meaningful.Need both for informed decision-makinghttps://t.co/V5qfEDHslQ

— Steven Cohn, MD (@preopconsult) November 30, 2022

RCT | Rivaroxaban prophylaxis in noncirrhotic portal vein thrombosis.

2 Dec, 2022 | 14:24h | UTC

Rivaroxaban Prophylaxis in Noncirrhotic Portal Vein Thrombosis – NEJM Evidence

Commentary on Twitter

This #RCT examined the use of rivaroxaban to reduce risk of venous thromboembolism (VTE) in pts with non-cirrhotic chronic portal vein thrombosis (PVT). Daily rivaroxaban reduced incidence of VTE and did not increase major bleeding events. https://t.co/CbenUb8ZWz #LiverTwitter pic.twitter.com/bgN1QS171j

— NEJM Evidence (@NEJMEvidence) November 22, 2022

Cohort Study | Tobacco smoking and risks of more than 470 diseases in China.

2 Dec, 2022 | 14:14h | UTC

Tobacco smoking and risks of more than 470 diseases in China: a prospective cohort study – The Lancet Public Health

Commentary: Smoking increases the risks of 56 diseases in Chinese adults – Oxford University

M-A | Sodium restriction in patients with heart failure.

1 Dec, 2022 | 14:08h | UTC

Sodium Restriction in Patients With Heart Failure: A Systematic Review and Meta-Analysis of Randomized Clinical Trials – Circulation: Heart Failure (link to abstract – $ for full-text)

Commentary: Sodium Restriction No Help, No Harm in HF, Meta-analysis Confirms – TCTMD

Commentary on Twitter

In a meta-analysis of 17 RCT incl. the SODIUM-HF RCT, dietary sodium restriction did not reduce the risk of death or hospitalization in patients w/ HF @justinezekowitz @CVC_UAlberta #AHAJournals https://t.co/7xEr1bJgkz pic.twitter.com/4Gfrlx264i

— Circ: Heart Failure (@CircHF) November 17, 2022

Phase 2b RCT | Cannabidiol oil failed to relieve symptoms in advanced cancer.

1 Dec, 2022 | 14:04h | UTC

Phase IIb Randomized, Placebo-Controlled, Dose-Escalating, Double-Blind Study of Cannabidiol Oil for the Relief of Symptoms in Advanced Cancer (MedCan1-CBD) – Journal of Clinical Oncology

Commentary: Cannabis oil failed to improve pain or quality of life in palliative care cancer patients, study shows – The Guardian

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Systematic Review: Cannabis-based products for chronic pain.

Podcast: #338 LIVE! Medical Cannabis: Is it still dope? – The Curbsiders

Medicinal Cannabis for Chronic Pain: The Bermuda Triangle of Low Quality Studies, Countless Meta-analyses and Conflicting Recommendations – European Journal of Pain

RCT: Effect of medical marijuana card ownership on pain, insomnia, and affective disorder symptoms in adults.

Cohort Study: Long-term cannabis use is associated with cognitive deficits and smaller hippocampal volume in midlife.

AHA Scientific Statement | How does cannabis use affect brain health? Caution advised, more research needed.

M-A: Birth outcomes of neonates exposed to marijuana in utero.

Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.

Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions.

The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use.

Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.

Guideline: Medical cannabis or cannabinoids for chronic pain.

Cannabis and Cannabinoid Analgesia position statement – “Due to the lack of high-quality clinical evidence, the IASP does not currently endorse general use of cannabis and cannabinoids for pain relief.”

NICE Guideline: Cannabis-Based Medicinal Products

Consensus recommendations for perioperative management of cannabis and cannabinoid-based medicine users

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Short Review: Drug Interactions with Cannabinoids

Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain

Review: Considerations for cannabinoids in perioperative care by anesthesiologists.

Review: Cannabis-based Medicines and the Perioperative Physician

Study: Cannabis Use Disorder May Increase the Risk of Cardiovascular Events in Major Elective Surgeries

Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know

Perioperative Care of Cannabis Users: A Comprehensive Review of Pharmacological and Anesthetic Considerations

RCT | Combining loop with thiazide diuretics for decompensated heart failure.

1 Dec, 2022 | 14:02h | UTC

Combining loop with thiazide diuretics for decompensated heart failure: the CLOROTIC trial – European Heart Journal

Commentary on Twitter

Combining loop with thiazide diuretics for decompensated heart failure: the CLOROTIC trial https://t.co/wGfKpo03H6 @escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/VfnQnp2AKa

— European Society of Cardiology Journals (@ESC_Journals) November 30, 2022

M-A | Efficacy and safety of COVID-19 inactivated vaccine.

1 Dec, 2022 | 14:00h | UTC

Efficacy and safety of COVID-19 inactivated vaccine: A meta-analysis – Frontiers in Medicine

Collection of Cochrane evidence on diagnosing tuberculosis.

1 Dec, 2022 | 13:56h | UTC

Collection of Cochrane evidence on diagnosing tuberculosis – Cochrane Library

RCT | Medical masks vs. N95 respirators for preventing COVID-19 among health care workers.

30 Nov, 2022 | 13:52h | UTC

Medical Masks Versus N95 Respirators for Preventing COVID-19 Among Health Care Workers: A Randomized Trial – Annals of Internal Medicine

News Release: In some settings, medical masks may offer similar effectiveness to N95 respirators for preventing COVID-19 infection among health care workers – American College of Physicians

Editorial: Comparative Effectiveness of Mask Type in Preventing SARS-CoV-2 in Health Care Workers: Uncertainty Persists – Annals of Internal Medicine

Commentary on Twitter

A randomized trial of medical masks vs N95s in health care workers to prevent Covid https://t.co/CSJkFLE15z
—It's woefully underpowered but ruled out a doubling of hazard for use of medical masks
—In 3 of the 4 countries there was less risk with N95s (p=NS) pic.twitter.com/B7iBvT1J9B

— Eric Topol (@EricTopol) November 28, 2022

ACP Guidance | Outpatient treatment of confirmed COVID-19.

30 Nov, 2022 | 13:54h | UTC

Outpatient Treatment of Confirmed COVID-19: Living, Rapid Practice Points From the American College of Physicians (Version 1) – Annals of Internal Medicine

Editorial: Ongoing Need for Clinical Trials and Contemporary End Points for Outpatient COVID-19 – Annals of Internal Medicine

Commentary: New ACP living practice points, mortality data on COVID-19 – ACP Internist

Cohort Study | Acute and postacute sequelae associated with SARS-CoV-2 reinfection.

30 Nov, 2022 | 13:42h | UTC

Acute and postacute sequelae associated with SARS-CoV-2 reinfection – Nature Medicine

News Release: Repeat COVID-19 infections increase risk of organ failure, death – Washington University School of Medicine

Commentary: SARS-CoV-2 Reinfection Ups Risks for Death, Hospitalization – HealthDay

German guideline on diverticular disease/diverticulitis.

30 Nov, 2022 | 13:41h | UTC

German guideline diverticular disease/diverticulitis: Part I: Methods, pathogenesis, epidemiology, clinical characteristics (definitions), natural course, diagnosis and classification – UEG Journal

Editorial: New German guidelines for the management of diverticulitis – UEG Journal

Systematic Review: Antibiotics for uncomplicated diverticulitis.

Efficacy and Safety of Non-Antibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-Label, Non-Inferiority Trial – Annals of Surgery (link to abstract – $ for full-text)

The WSES/SICG/ACOI/SICUT/AcEMC/SIFIPAC guidelines for diagnosis and treatment of acute left colonic diverticulitis in the elderly – World Journal of Emergency Surgery

Diagnosis and Management of Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

Colonoscopy for Diagnostic Evaluation and Interventions to Prevent Recurrence After Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

Changing Paradigms in the Management of Acute Uncomplicated Diverticulitis – Scandinavian Journal of Surgery

Elective surgical management of diverticulitis – Current Problems in Surgery

Management of Colonic Diverticulitis – Agency for Healthcare Research and Quality

2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting – World Journal of Emergency Surgery

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Treatment of Left-Sided Colonic Diverticulitis – Diseases of the Colon & Rectum

Podcast | Advanced lipidology.

30 Nov, 2022 | 13:32h | UTC

#361 Advanced Lipidology – The Curbsiders

Podcast | Perioperative medicine.

30 Nov, 2022 | 13:33h | UTC

#365: Perioperative Medicine with Anesthesiologist Dr. Angela Selzer – The Curbsiders

WHO renames “monkeypox” as “mpox” to help destigmatize the disease.

29 Nov, 2022 | 14:27h | UTC

WHO recommends new name for monkeypox disease – World Health Organization

Commentaries:

WHO to phase out the name ‘monkeypox’ for ‘mpox’ – STAT

WHO renames monkeypox as mpox, citing racist stigma – NPR

The Future of Monkeypox – The Atlantic

Monkeypox given new name by global health experts – BBC

Monkeypox to be renamed mpox to avoid stigma, says WHO – The Guardian

Commentary on Twitter (thread – click for more)

Following consultations, WHO will begin using a new term for “#monkeypox” disease: '#mpox'.
Both names will be used simultaneously for one year while 'monkeypox' is phased out https://t.co/VT9DAdYrGY pic.twitter.com/Ae6zgkefPI

— World Health Organization (WHO) (@WHO) November 28, 2022

WHO Global tuberculosis report 2022.

29 Nov, 2022 | 14:25h | UTC

Global tuberculosis report 2022 – World Health Organization

News Release: Tuberculosis deaths and disease increase during the COVID-19 pandemic – World Health Organization

Video Summary: WHO Global Tuberculosis Report 2022: Key findings and messages – World Health Organization

Commentary on Twitter (thread – click for more)

🆕 WHO 2022 Global TB report 🧵

For the first time in many years, an increase has been reported in the number of people falling ill with #tuberculosis (TB) and drug-resistant TB.

📌 https://t.co/AvVFJ6j1E5 pic.twitter.com/dPywHXZ6ND

— World Health Organization (WHO) (@WHO) October 27, 2022

M-A | Thiazide diuretics and fracture risk.

29 Nov, 2022 | 14:23h | UTC

Thiazide Diuretics and Fracture Risk: A Systematic Review and Meta-Analysis of Randomized Clinical Trials – JBMR Plus

Study shows Omicron sublineage BQ.1.1 is resistant to all monoclonal antibodies.

29 Nov, 2022 | 14:16h | UTC

Omicron sublineage BQ.1.1 resistance to monoclonal antibodies – The Lancet Infectious Diseases

Commentaries:

New Omicron subvariant BQ.1.1 resistant to all therapeutic antibodies, study finds – Deutsches Primatenzentrum (DPZ)/German Primate Center

Omicron variant BQ.1.1 found to be resistant to all monoclonal antibody treatments – MedicalXpress

Commentary on Twitter

The BQ.1.1 variant, as compared with many of the other new variants, is resistant to all clinically used monoclonal antibodies.
BQ.1/BQ.1.1 are now the dominant variants in the United Stateshttps://t.co/PCFPSGF2uy @TheLancetInfDis pic.twitter.com/dHucxoGokC

— Eric Topol (@EricTopol) November 19, 2022

The ‘Ten Commandments’ for the 2022 European Society of Cardiology guidelines on cardio-oncology.

29 Nov, 2022 | 14:13h | UTC

The ‘Ten Commandments’ for the 2022 European Society of Cardiology guidelines on cardio-oncology – European Journal of Cardiology

Original guideline: #ESCCongress | 2022 ESC Guidelines on cardio-oncology.

Evidence-based approach to the surgical management of acute pancreatitis.

29 Nov, 2022 | 14:10h | UTC

Evidence-Based Approach to the Surgical Management of Acute Pancreatitis – The Surgery Journal

Intravenous fluid therapy in patients with severe acute pancreatitis admitted to the intensive care unit: a narrative review – Intensive Care Medicine

Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis – New England Journal of Medicine (link to abstract – $ for full-text)

Acute Pancreatitis: Diagnosis and Treatment – Drugs

Revised Clinical Practice Guidelines of the Korean Pancreatobiliary Association for Acute Pancreatitis – Gut and Liver

Guidelines for the management of patients with severe acute pancreatitis, 2021 – Anaesthesia Critical Care & Pain Medicine

Evidence-Based Disposition of Acute Pancreatitis – emDocs

2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery

American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis

Pancreatitis – National Institute for Health and Care Excellence

Podcast | Back pain update.

29 Nov, 2022 | 14:07h | UTC

#368 Back Pain Update with
Dr. Austin Baraki – The Curbsiders

Podcast | Opioid use disorder and acute pain in hospitalized patients.

29 Nov, 2022 | 14:05h | UTC

#366 Opioid Use Disorder and Acute Pain in the Hospitalized Patient – The Curbsiders

Cohort Study | Trends and risk factors for venous thromboembolism among hospitalized medical patients.

29 Nov, 2022 | 14:04h | UTC

Trends and Risk Factors for Venous Thromboembolism Among Hospitalized Medical Patients – JAMA Network Open

Commentary on Twitter

1.2% of hospitalized patients developed a hospital-associated venous thromboembolism (HA-VTE), slightly increasing from 2013-2016 (1.1-1.6%). 78% happened after discharge; HA-VTE were linked to higher risk of readmission and death. @KPDOR https://t.co/cB8VhY7k7X #OAResearch

— JAMA Network Open (@JAMANetworkOpen) November 21, 2022

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