Internal Medicine
Physicians need to openly discuss medical mistakes and near misses
16 Jul, 2017 | 23:48h | UTCOpinion: Physicians need to openly discuss medical mistakes and near misses – STAT News (free)
Guideline: Human Papillomavirus Vaccination
16 Jul, 2017 | 23:57h | UTCGuideline: Human Papillomavirus Vaccination – American College of Obstetricians and Gynecologists Recommendations and Conclusions (free)
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Diagnosis and Management in Young People
16 Jul, 2017 | 23:35h | UTCClinical Review: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Diagnosis and Management in Young People: A Primer – Frontiers in Pediatrics (free)
Diabetes Mellitus and Heart Failure
16 Jul, 2017 | 23:36h | UTCClinical Review: Diabetes Mellitus and Heart Failure – American Journal of Medicine (free)
Association of Changes in Diet Quality with Total and Cause-Specific Mortality
16 Jul, 2017 | 12:43h | UTCAssociation of Changes in Diet Quality with Total and Cause-Specific Mortality – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Improvement in diet quality linked to decreased all-cause mortality – 2 Minute Medicine (free) AND Improving Diet Over Time May Reduce Risk of Death – MedPage Today (free registration required) Change in Diet Can Lower Mortality Risk – Medscape (free registration required) AND Eating a Little Bit Healthier Helps You Live Longer – TIME (free) AND A Range of Healthy Dietary Changes Could Help You Live Longer – Physician’s First Watch (free)
Non-invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of COPD
16 Jul, 2017 | 12:48h | UTCNon-invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease – Cochrane Library (free)
NIV reduces mortality and endotracheal intubation in patients with acute hypercapnic respiratory failure secondary to an acute exacerbation COPD.
Insulin pumps not much better than multiple injections for intensive control of type 1 diabetes
16 Jul, 2017 | 12:44h | UTCInsulin pumps not much better than multiple injections for intensive control of type 1 diabetes – NIHR Signal (free)
Original article: Relative effectiveness of insulin pump treatment over multiple daily injections and structured education during flexible intensive insulin treatment for type 1 diabetes: cluster randomised trial (REPOSE) – The BMJ (free)
Clinical Practice Guidelines for Enhanced Recovery After Colon and Rectal Surgery
16 Jul, 2017 | 12:41h | UTCSee other Enhanced Recovery After Surgery (ERAS) Guidelines and Reviews in our collection and in the ERAS Society Website.
Clinical Guidelines for the Management of Adrenal Incidentaloma
16 Jul, 2017 | 12:42h | UTCClinical Guidelines for the Management of Adrenal Incidentaloma – Endocrinology and Metabolism (free)
NCCN Guidelines Insights: Antiemesis
13 Jul, 2017 | 20:57h | UTCNCCN Guidelines Insights: Antiemesis, Version 2.2017 (free)
Surgery for early prostate cancer may not save lives
16 Jul, 2017 | 12:40h | UTCFollow-up of Prostatectomy versus Observation for Early Prostate Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Long-term, surgery for localized prostate cancer offers little extra benefit – Reuters (free) AND No Benefit with Surgery for Low-Risk Prostate Cancer – MedPage Today (free registration required) AND Prostatectomy for Localized Prostate Cancer Doesn’t Improve Long-Term Survival – Physician’s First Watch (free) AND Surgery for Early Prostate Cancer May Not Save Lives – Washington University in St. Louis, via NewsWise (free)
“Most men just as likely to survive with limited or no treatment” (from NewsWise)
Should we screen for cirrhosis?
13 Jul, 2017 | 20:48h | UTCHead To Head: Should we screen for cirrhosis? – The BMJ (free)
Pros and cons of screening high risk patients for liver cirrhosis.
Review: Supervised Treadmill Exercise Therapy for Peripheral Artery Disease
13 Jul, 2017 | 20:44h | UTCReview: Supervised Treadmill Exercise Therapy for Peripheral Artery Disease – American College of Cardiology, Latest in Cardiology (free)
Related guideline: 2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease: Executive Summary : A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines (free) AND Summary: AHA/ACC Guideline on the Management of Lower Extremity Peripheral Artery Disease (free)
Pericarditis as a Marker of Occult Cancer and a Prognostic Factor for Cancer Mortality
13 Jul, 2017 | 20:46h | UTCPericarditis as a Marker of Occult Cancer and a Prognostic Factor for Cancer Mortality – Circulation (link to abstract – $ for full-text)
Commentary: Pericarditis as a Marker of Occult Cancer – American College of Cardiology, Latest in Cardiology (free)
Study: No effect of commercial cognitive training on cognitive function
13 Jul, 2017 | 20:43h | UTCNo Effect of Commercial Cognitive Training on Neural Activity During Decision-Making – The Journal of Neuroscience (link to abstract – $ for full-text)
Commentaries: Brain training has no effect on decision-making or cognitive function – University of Pennsylvania School of Medicine, via NewsWise (free) AND Brain Training: No Effect on Cognitive Performance – Medscape (free registration required) AND Brain-training games don’t really train brains, a new study suggests – The Washington Post (a few articles per month are free)
Blood pressure and in-hospital outcomes in patients presenting with ischaemic stroke
12 Jul, 2017 | 20:13h | UTCBlood pressure and in-hospital outcomes in patients presenting with ischaemic stroke – European Heart Journal (link to abstract – $ for full-text)
Commentary: Blood Pressure and Outcomes After Ischemic Stroke – American College of Cardiology, Latest in Cardiology (free)
Related article: Editorial: Blood Pressure in Acute Stroke Still No Answer for Management – Stroke (free PDF)
Observational analysis of over 300.000 patients suggests a J-shaped, or U-shaped relationships between BP and outcomes (both lower and higher BP levels detrimental). Among patients submitted to thrombolytic therapy, there were fewer complications with lower blood pressure.
Advances in the causes and management of community acquired pneumonia in adults
12 Jul, 2017 | 15:51h | UTCState of The Art Review: Advances in the causes and management of community acquired pneumonia in adults – The BMJ (free)
Antidepressant Switching vs Augmentation in Resistent Depression?
12 Jul, 2017 | 15:24h | UTCEffect of Antidepressant Switching vs Augmentation on Remission Among Patients With Major Depressive Disorder Unresponsive to Antidepressant Treatment: The VAST-D Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Study Compares Switching Meds vs an Additional Med for Patients Unresponsive to an Antidepressant – The Jama Network (free) AND For Treatment-Resistant Depression, Add an Antipsychotic or Switch Antidepressants? – Physician’s First Watch (free)
Augmentation with aripiprazole led to a modestly increased likelihood of remission, but with more adverse effects. “Given the small effect size and adverse effects associated with aripiprazole, further analysis including cost-effectiveness is needed to understand the net utility of this approach”.
Clinical characteristics and outcomes of diffuse alveolar hemorrhage in patients with systemic lupus erythematosus
12 Jul, 2017 | 15:33h | UTCClinical characteristics and outcomes of diffuse alveolar hemorrhage in patients with systemic lupus erythematosus – Seminars in Arthritis & Rheumatism (link to abstract – $ for full-text)
Commentary: Prompt Evaluation of Lung Bleeds Needed in Lupus – MedPage Today (free registration required)
“Low hemoglobin, low C4 and hypoxia are features of poor outcome” (from MedPage Today)
Type 2 diabetes and osteoporosis: a guide to optimal management
11 Jul, 2017 | 21:48h | UTCType 2 diabetes and osteoporosis: a guide to optimal management – Journal of Clinical Endocrinology & Metabolism (link to abstract – $ for full-text)
Commentaries: Specific diabetes medications to protect bone health recommended – Endocrine Society, via ScienceDaily (free) AND Advice for Optimal Management of Diabetes and Osteoporosis – Medscape (free registration required)
Alendronate may reduce hip fracture risk in older patients using prednisolone
12 Jul, 2017 | 14:55h | UTCAssociation Between Alendronate Use and Hip Fracture Risk in Older Patients Using Oral Prednisolone – JAMA (link to abstract – $ for full-text)
Commentaries: Alendronate Cuts Hip-Fracture Rates in High-Risk Elderly – Medscape (free registration required) AND Alendronate helps cut hip fracture risk with prednisolone – OnMedica (free) AND Alendronate Might Help Protect Against Hip Fracture in Patients Taking Prednisolone – Physician’s First Watch (free)
Retrospective cohort suggests alendronate might reduce fracture risk in the short term in elderly patients taking prednisolone.
Positive airway pressure doesn’t reduce cardiovascular events and death in adults with sleep apnea
12 Jul, 2017 | 15:01h | UTCAssociation of Positive Airway Pressure With Cardiovascular Events and Death in Adults With Sleep Apnea: A Systematic Review and Meta-analysis – JAMA (link to abstract – $ for full-text)
Commentaries: More Doubt Cast on CPAP for Reducing CVD Risk in Sleep Apnea Patients – MedPage Today (free registration required) AND Positive airway pressure doesn’t reduce heart risk with sleep apnea – Reuters (free)
“PAP for obstructive sleep apnea improves quality of life but not CV events or BP with up to 5 years of follow up” (RT @AnilMakam see Tweet)
Diagnosis and Management of Resistant Hypertension
11 Jul, 2017 | 21:39h | UTCSummary with 10 key points to remember: Diagnosis and Management of Resistant Hypertension – American College of Cardiology, Latest in Cardiology (free)
Original article: Diagnosis and management of resistant hypertension – Heart (link to abstract – $ for full-text)
Electrocardiograms in Low-Risk Patients Undergoing An Annual Health Examination
11 Jul, 2017 | 19:22h | UTCElectrocardiograms in Low-Risk Patients Undergoing An Annual Health Examination – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: More than 20% of low-risk patients receive an ECG as part of annual health exam – Institute for Clinical Evaluative Sciences (ICES) (RT @ICESOntario and @ChooseWiselyCA see Tweet) (free) AND ECGs Common in Low-Risk Patients After Annual Health Exam, Leading to More Cardiac Care – American College of Cardiology, Latest in Cardiology (free) Routine ECG With Annual Physical Questioned – MedPage Today (free registration required)
Meta-analysis: Dual Versus Triple Antithrombotic Therapy in Patients Undergoing Percutaneous Coronary Intervention
11 Jul, 2017 | 21:26h | UTCMeta-analysis: Safety and Efficacy of Dual Versus Triple Antithrombotic Therapy in Patients Undergoing Percutaneous Coronary Intervention – American Journal of Medicine (link to abstract – $ for full-text)
Source: EvidenceAlerts (free resource to find articles of interest)
“In patients receiving anticoagulant therapy, a strategy of single antiplatelet therapy confers a benefit of less major bleeding with no difference in all-cause mortality, cardiovascular mortality, major adverse cardiac events, myocardial infarction, stent thrombosis, or thromboembolic event rate compared with dual antiplatelet therapy”.