Internal Medicine
Seasonal influenza: managing cases in critical care units
11 Aug, 2017 | 12:35h | UTCGuideline: Seasonal influenza: managing cases in critical care units – Public Health England (free PDF)
Source: Critical Care Reviews Newsletter
On-demand pre-exposure prophylaxis for HIV
10 Aug, 2017 | 22:31h | UTCEfficacy, safety, and effect on sexual behaviour of on-demand pre-exposure prophylaxis for HIV in men who have sex with men: an observational cohort study – The Lancet HIV (free registration required)
Commentaries: PrEP on demand or every day? – The Lancet HIV (free registration required) AND HIV pre-exposure prophylaxis can be taken as needed – Reuters (free)
“four doses of PrEP around the time of sexual activity cut the risk of HIV by 97 percent” (from Reuters Health)
Nephrolithiasis more common in patients with gout
10 Aug, 2017 | 22:32h | UTCCommentaries: Gout Patients Run Higher Risk of Kidney Stones – MedPage Today (free registration required) AND Gout associated with elevated risk for kidney stones – MedWire News (free)
“60% increased risk of first-time nephrolithiasis versus general population, with little protection from allopurinol” (from MedPage Today)
Depression and risk of death following coronary artery disease diagnosis
10 Aug, 2017 | 22:33h | UTCThe association of depression at any time to the risk of death following coronary artery disease diagnosis – European Heart Journal – Quality of Care and Clinical Outcomes (link to abstract – $ for full-text)
Commentaries: Having depression and heart disease could double death risk – Medical News Today (free) AND Death risk doubles for heart patients with depression – Cardiovascular Business (free)
Related: AAFP Guideline for the Detection and Management of Post–Myocardial Infarction Depression – Annals of Family Medicine (free)
Strategies to prevent death by suicide
10 Aug, 2017 | 22:28h | UTCStrategies to prevent death by suicide: meta-analysis of randomised controlled trials – British Journal of Psychiatry (link to abstract – $ for full-text)
Commentary: Brief Intervention and Contact (BIC) to prevent suicide – Dave Cesarini, via Medium (free)
Related article: Effectiveness of brief intervention and contact for suicide attempters: a randomized controlled trial in five countries – Bulletin of the World Health Organization (free)
Source: Psychiatry Research Review
“The WHO BIC is a promising suicide prevention strategy. No other intervention showed a statistically significant effect in reducing suicide”.
Effects of CPAP and Mandibular Advancement Devices on Quality of Life in Sleep Apnea
10 Aug, 2017 | 22:29h | UTCEffects of CPAP and Mandibular Advancement Devices on Health-Related Quality of Life in OSA – Chest (free)
See also a recent study showing CPAP does not reduce cardiovascular events in our July 13th issue (see #2)
“CPAP is effective in improving health-related quality of life in OSA, and Mandibular Advancement Devices may be just as effective, but further RCTs comparing the two treatments are required”.
Suicide Prevention in an Emergency Department Population
10 Aug, 2017 | 22:27h | UTCSuicide Prevention in an Emergency Department Population: The ED-SAFE Study – JAMA Psychiatry (link to abstract – Free Full Text PDF via @unpaywall)
Commentaries: Intervention Phone Calls May Save The Lives Of Suicidal Patients, Reduce New Attempts, Trial Finds – Medical Daily (free) AND National study shows interventions like telephone calls can reduce suicides – EurekAlert (free) AND Intervention Curbs New Suicide Attempts in At-Risk ED Patients – Medscape (free registration required)
Source: Psychiatry Research Review
“Patients who received a multifaceted intervention that included follow-up telephone calls resulted in a 30 percent reduction in future suicide attempts” (from Medical Daily)
Neuroprotective Diets Are Associated with Better Cognitive Function
10 Aug, 2017 | 22:22h | UTCCommentaries: Cognitive decline could be reduced with a Mediterranean-style diet – Medical News Today (free) AND Mediterranean-style diets linked to better brain function in older adults – Journal of the American Geriatrics Society Research Summary (free)
Diet and Risk of Cholecystectomy
10 Aug, 2017 | 22:23h | UTCDiet and Risk of Cholecystectomy: A Prospective Study Based on the French E3N Cohort – American Journal of Gastroenterology (link to abstract – $ for full-text)
Commentary: Fewer gallbladder surgeries with Mediterranean diets – Reuters (free)
Challenges in Treating Cardiovascular Disease: Restricting Sodium and Managing Hyperkalemia
10 Aug, 2017 | 21:45h | UTCReview: Challenges in Treating Cardiovascular Disease: Restricting Sodium and Managing Hyperkalemia – Mayo Clinic Proceedings (free)
Surgical Guidelines for Perioperative Management of Older Adults
10 Aug, 2017 | 20:48h | UTC
Antibiotic prophylaxis is not indicated prior to dental procedures for prevention of periprosthetic joint infections
10 Aug, 2017 | 21:20h | UTCSource: EvidenceAlerts (free resource to find articles of interest)
Functional Gain and Pain Relief After Total Joint Replacement According to Obesity Status
10 Aug, 2017 | 19:27h | UTCFunctional Gain and Pain Relief After Total Joint Replacement According to Obesity Status – The Journal of Bone & Joint Surgery (link to abstract – $ for full-text)
Commentaries: Joint Replacement Weight Loss Requirements Challenged – Medscape (free registration required) AND Pain relief, functional outcomes after joint replacement similar in obese and normal-weight patients – News Medical (free)
Effects of CPAP and Mandibular Advancement Devices on Health-Related Quality of Life in OSA
10 Aug, 2017 | 18:36h | UTCEffects of CPAP and Mandibular Advancement Devices on Health-Related Quality of Life in OSA – Chest (free)
See also a recent study showing CPAP does not reduce cardiovascular events in our July 13th issue (see #2)
“CPAP is effective in improving health-related quality of life in OSA, and Mandibular Advancement Devices may be just as effective, but further RCTs comparing the two treatments are required”.
Continuous glucose monitoring in the ICU: clinical considerations and consensus
10 Aug, 2017 | 18:08h | UTCReview: Continuous glucose monitoring in the ICU: clinical considerations and consensus – Critical Care (free)
What do hypnotics cost hospitals and healthcare?
10 Aug, 2017 | 17:16h | UTCWhat do hypnotics cost hospitals and healthcare? – F1000 Research (free)
Source: Hospital Medicine Virtual Journal Club
“A best estimate is that U.S. costs of hypnotic harms to healthcare systems are on the order of $55 billion, but conceivably might be as low as $10 billion or as high as $100 billion”.
Treating subclinical thyroid dysfunction in pregnancy probably has no benefit
9 Aug, 2017 | 17:36h | UTCTreating subclinical thyroid dysfunction in pregnancy probably has no benefit – NIHR Signal (free) (RT see Tweet)
Related: Subclinical Hypothyroidism – NEJM Resident 360 (free) AND Levothyroxine Shows No Benefit in Older Adults with Subclinical Hypothyroidism – Physician’s First Watch (free)
“Treating subclinical thyroid dysfunction in pregnancy probably has no benefit” (RT @NIHR_DC see Tweet)
Effect of marijuana use on cardiovascular and cerebrovascular mortality
10 Aug, 2017 | 17:13h | UTCCommentaries: Marijuana associated with three-fold risk of death from hypertension – European Society of Cardiology, via Science Daily (free) AND Marijuana use holds three-fold blood pressure death risk: study – Reuters (free) AND Marijuana Use Tied to Death from Hypertension, Study Suggests – Physician’s First Watch (free) AND Marijuana ‘may be worse than cigarettes for cardiovascular health’ – Medical News Today (free)
How Low Is Too Low With Salt in Heart Failure?
9 Aug, 2017 | 17:02h | UTCOpinion: How Low Is Too Low With Salt in Heart Failure? Randomized Studies Needed to Resolve Concern – Circulation (free)
See more on sodium intake and cardiovascular disease in our July 11th issue (see #1)
Association of Estimated Sodium Intake With Adverse Cardiac Structure and Function
9 Aug, 2017 | 17:03h | UTCAssociation of Estimated Sodium Intake With Adverse Cardiac Structure and Function – Journal of The American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Typical adults eat enough salt to damage heart – Reuters (free) AND High Dietary Sodium Linked to Subclinical Cardiac Dysfunction – Medscape (free registration required)
Alternatives to hospital admission for people aged over 65 years
9 Aug, 2017 | 17:58h | UTCA systematic review to identify and assess the effectiveness of alternatives for people over the age of 65 who are at risk of potentially avoidable hospital admission – BMJ Open (free) (RT @NIHR_DC)
Alternatives to hospital admission for people aged over 65 years can be safe and reduce costs across a range of acute and chronic conditions.
How long should I take antibiotics?
9 Aug, 2017 | 17:04h | UTCRelated: The antibiotic course has had its day – The BMJ (free) AND Keep taking the tablets: three reasons to stay the full antibiotics course – The Conversation (free) (RT @Onisillos) AND Why you really should take your full course of antibiotics – The Conversation (free)
Acute mesenteric ischemia: guidelines
9 Aug, 2017 | 16:57h | UTC
Clinical management of hypercholesterolaemia in patients with acute coronary syndromes
9 Aug, 2017 | 17:01h | UTC
Severe infections and subsequent delayed cardiovascular disease
9 Aug, 2017 | 16:52h | UTCCommentary: Pneumonia Or Sepsis in Adults Associated With Increased Risk of Cardiovascular Disease – European Society of Cardiology Press Releases (free)


