Internal Medicine
Salt intake and Cardiovascular Disease
9 Jul, 2017 | 00:28h | UTCSalt intake and Cardiovascular Disease – European Heart Journal (free)
Commentary: CardioBrief: Int’l Experts Call Sodium Guidelines Far Too Restrictive – MedPage Today (free)
Summary of the technical report on sodium intake and cardiovascular disease with key recommendations for individuals and policymakers.
Pretreatment fasting plasma glucose and insulin modify dietary weight loss success
9 Jul, 2017 | 00:38h | UTCPretreatment fasting plasma glucose and insulin modify dietary weight loss success: results from 3 randomized clinical trials – American Journal of Clinical Nutrition (link to abstract – $ for full-text)
Commentaries: Fasting blood sugar, fasting insulin identified as new biomarkers for weight loss – University of Copenhagen, via ScienceDaily (free) AND Low-Fat or Low Carb for Weight Loss? It Depends on Your Glucose Metabolism – EbioMedicine (free)
Individuals with diabetes or pre-diabetes seem to have better results with low-carb diets.
Gabapentin for chronic neuropathic pain in adults
9 Jul, 2017 | 00:26h | UTCCochrane Review: Gabapentin for chronic neuropathic pain in adults – Cochrane Library (link to abstract – $ for full-text)
Commentary: Analgesic Effects of Gabapentin Assessed in Chronic Neuropathic Pain – MPR (free)
“Gabapentin at doses of 1800 mg to 3600 mg daily (1200 mg to 3600 mg gabapentin encarbil) can provide good levels of pain relief to some people with postherpetic neuralgia and peripheral diabetic neuropathy”.
Doxycycline may be a safer first option for treating a blistering skin condition
8 Jul, 2017 | 20:28h | UTCDoxycycline may be a safer first option for treating a blistering skin condition – NIHR Signal (free)
Original Article: Doxycycline versus prednisolone as an initial treatment strategy for bullous pemphigoid: a pragmatic, non-inferiority, randomised controlled trial – The Lancet (free) AND Editorial: Doxycycline: a first-line treatment for bullous pemphigoid? (free)
Guideline – Management of Crohn’s disease
7 Jul, 2017 | 14:06h | UTC
Guideline – Management of ulcerative colitis
7 Jul, 2017 | 14:06h | UTC
Free online course – Easing the burden of obesity, diabetes and cardiovascular disease
7 Jul, 2017 | 14:09h | UTCFree online course, starts July 17: Easing the burden of obesity, diabetes and cardiovascular disease – University of Sidney and Coursera
Guidelines for the investigation and management sepsis in pregnancy
7 Jul, 2017 | 14:07h | UTC
Cases of recurrent Clostridium difficile infection are increasing
7 Jul, 2017 | 14:04h | UTCCommentaries: Cases of recurrent Clostridium difficile infection are soaring – University of Pennsylvania School of Medicine, via EurekAlert (free) AND Multiply Recurrent C difficile Infection Rates Sharply Rise – Medscape (free registration required) AND Demand for FMT likely to increase with rise in multiply recurrent C. difficile cases – 2 Minute Medicine (free) AND Marked increase seen in multiply recurrent C diff – CIDRAP (free)
Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma
7 Jul, 2017 | 14:03h | UTCEffect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Add-On Azithromycin Associated with Fewer Asthma Exacerbations – Physician’s First Watch (free)
Long-term health status and trajectories of seriously injured patients
7 Jul, 2017 | 14:01h | UTCLong-term health status and trajectories of seriously injured patients: A population-based longitudinal study – PLOS Medicine (free) (RT @karimbrohi see Tweet – “Trauma is a chronic disease”)
“The prevalence of reporting problems at 36-months postinjury was 37% for mobility, 21% for self-care, 47% for usual activities, 50% for pain/discomfort, and 41% for anxiety/depression… the prevalence of ongoing problems at 3-years postinjury is high, confirming that serious injury is frequently a chronic disorder”
Diabetes and Ramadan: Practical guidelines
7 Jul, 2017 | 13:57h | UTCDiabetes and Ramadan: Practical guidelines – Diabetes Research and Clinical Practice (free)
Rivastigmine reviewed: doubts about dementia drug
7 Jul, 2017 | 13:56h | UTCRivastigmine reviewed: doubts about dementia drug – Evidently Cochrane (free)
Related review: Rivastigmine for people with Alzheimer’s disease – Cochrane Library (link to abstract – $ for full-text)
“”Sadly, “small” and “of uncertain clinical importance” are the words chosen by the Cochrane reviewers to describe…” (RT @CochraneUK see Tweet)
Benefits and Risks of Antithrombotic Therapy in Essential Thrombocythemia
7 Jul, 2017 | 13:59h | UTCBenefits and Risks of Antithrombotic Therapy in Essential Thrombocythemia: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Review Questions Antithrombotic Tx in Essential Thrombocythemia – Physician’s Briefing (free)
Cardiac involvement in DRESS syndrome
7 Jul, 2017 | 13:48h | UTCReview: Cardiac involvement in DRESS syndrome – Asian Pacific Journal of Allergy and Immunology (free PDF)
Current status of lupus nephritis
7 Jul, 2017 | 13:49h | UTCReview: Current status of lupus nephritis – Indian Journal of Medical Research (free)
Imaging and Management of Incidental Renal Lesions
7 Jul, 2017 | 13:44h | UTCReview: Imaging and Management of Incidental Renal Lesions – BioMed Research International (free)
Pharmacologic Management of Type 2 Diabetes Mellitus: Available Therapies
7 Jul, 2017 | 13:46h | UTCReview: Pharmacologic Management of Type 2 Diabetes Mellitus: Available Therapies – American Journal of Medicine (free)
Peri-operative blood management
7 Jul, 2017 | 13:43h | UTCReview: Peri-operative blood management – Indian Journal of Anesthesia (free)
Review of the Relationship between Red Meat Consumption and Cardiovascular Risk
7 Jul, 2017 | 13:41h | UTC
Non-alcoholic fatty liver disease: An expanded review
7 Jul, 2017 | 13:31h | UTCReview: Non-alcoholic fatty liver disease: An expanded review – World Journal of Hepatology (free)
The Association between the Mediterranean Dietary Pattern and Cognitive Health
7 Jul, 2017 | 13:25h | UTCReview: The Association between the Mediterranean Dietary Pattern and Cognitive Health: A Systematic Review – Nutrients (free)
Treating Anxiety in 2017: Optimizing Care to Improve Outcomes
5 Jul, 2017 | 21:49h | UTCTreating Anxiety in 2017: Optimizing Care to Improve Outcomes – JAMA (free)
“Exercise, mindfulness-based stress reduction = 1st-line treatments for anxiety; move on to SSRIs and CBT as needed” (RT @JAMA_current see Tweet)
Digoxin Use and Subsequent Clinical Outcomes in Patients With Atrial Fibrillation With or Without Heart Failure
5 Jul, 2017 | 18:24h | UTCSource: Hospital Medicine Virtual Journal Club
In this observational analysis, patients with atrial fibrillation without heart failure had increased risk of sudden cardiac death with digoxin use. Among patients with heart failure, digoxin use was associated with an increase in all‐cause death, cardiovascular death, sudden cardiac death, and death caused by HF/cardiogenic shock.
Certain OTC, less expensive hearing aids provide benefit similar to conventional hearing aid
5 Jul, 2017 | 20:48h | UTCPersonal Sound Amplification Products vs a Conventional Hearing Aid for Speech Understanding in Noise – JAMA (link to abstract – $ for full-text)
The Jama Network – For the Media: Certain OTC, less expensive hearing aids provide benefit similar to conventional hearing aid (free)
Commentaries: Less Expensive Hearing Devices May Work as Well as Traditional Hearing Aids – Physician’s First Watch (free) AND Study Boosts Case for OTC Hearing Aids – MedPage Today (free registration required) AND OTC Hearing Devices Effective Alternative for Some, Study Shows – Medscape (free registration required)
“Some over-the-counter sound amplification devices are nearly as effective as prescription hearing aids, according to a small JAMA study” (from Physician’s First Watch)