Internal Medicine
Research: Outcomes, experiences and palliative care in major stroke
8 Mar, 2018 | 21:32h | UTC““Palliative care” had connotations of treatment withdrawal and imminent death… practicing the principles of palliative care is needed, but the term “palliative care” should be avoided or reframed”.
See related articles on this subject: Palliative care: renaming as supportive care and integration into comprehensive cancer care – CMAJ (free) AND Perceptions of palliative care among patients with advanced cancer and their caregivers (free)
Research: Healthy diet may not offset high salt intake
8 Mar, 2018 | 21:33h | UTCRelation of Dietary Sodium (Salt) to Blood Pressure and Its Possible Modulation by Other Dietary Factors: The INTERMAP Study – Hypertension (link to abstract – $ for full-text)
Commentaries: Healthy diet may not offset high salt intake – Imperial College London (free) AND Dietary sodium’s impact may not be offset by other aspects of a diet – AHA / ASA Newsroom (free)
Opioid Wisely – Choosing Wisely Canada
8 Mar, 2018 | 21:29h | UTCOpioid Wisely – Choosing Wisely Canada (free)
Related Guideline: Guideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free)
See complete lists from Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
This campaign encourages thoughtful conversation between clinicians and patients to reduce harms associated with opioid prescribing, with recommendations relevant to different specialties.
Richard Lehman’s journal review – 5 March 2018
8 Mar, 2018 | 21:32h | UTCRichard Lehman’s journal review, 5 March 2018 – The BMJ (free)
Richard Lehman reviews the latest research in the top medical journals.
Guidelines for the management of cryptococcal disease in HIV-infected adults, adolescents and children
8 Mar, 2018 | 21:30h | UTCSee also: Key Messages AND Policy Brief (free PDF)
Research: Escalating Inhaled Glucocorticoids to Prevent Asthma Exacerbations
8 Mar, 2018 | 21:28h | UTCEditorial: Escalating Inhaled Glucocorticoids to Prevent Asthma Exacerbations (free for a limited period)
Trial 1: Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations – The New England Journal of Medicine (free for a limited period)
Trial 2: Quadrupling Inhaled Glucocorticoid Dose to Abort Asthma Exacerbations – The New England Journal of Medicine (free for a limited period)
Guidelines for Management of Sepsis and Septic Shock
8 Mar, 2018 | 21:26h | UTC
Research: Opioid Tapering in Community Outpatients With Chronic Pain
8 Mar, 2018 | 20:43h | UTCCommentary: Chronic Opioid Users May Wish to Taper Opioid Use – Physician’s Weekly (free)
Research: Comparative cardiovascular safety of non-steroidal anti-inflammatory drugs in patients with hypertension
8 Mar, 2018 | 20:44h | UTCComparative cardiovascular safety of non-steroidal anti-inflammatory drugs in patients with hypertension: a population-based cohort study – British Journal of Clinical Pharmacology (link to abstract – $ for full-text)
Commentary: Cardiovascular Risk Compared Among COX-2 Selective, Nonselective NSAIDs – MPR (free)
Research: Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria
8 Mar, 2018 | 20:31h | UTCColistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial – The Lancet (link to abstract – $ for full-text)
“Combination therapy was not superior to monotherapy”.
Position Statement: Role of cardiopulmonary exercise testing in clinical stratification in heart failure
8 Mar, 2018 | 20:29h | UTC
Perioperative stroke: pathophysiology and management
8 Mar, 2018 | 20:24h | UTCPerioperative stroke: pathophysiology and management – Synapse (free)
Source: Critical Care Reviews Newsletter
Points of Concern in Post Acute Kidney Injury Management
8 Mar, 2018 | 20:21h | UTCPoints of Concern in Post Acute Kidney Injury Management – Nephron (free)
Source: Critical Care Reviews Newsletter
Review: Infections Complicating Cirrhosis
8 Mar, 2018 | 20:20h | UTCInfections complicating cirrhosis – Liver International (free)
Source: Critical Care Reviews Newsletter
Reviews: Post-Contrast Acute Kidney Injury
8 Mar, 2018 | 20:18h | UTCSource: Critical Care Reviews Newsletter
Review: Pneumonia as a cardiovascular disease
8 Mar, 2018 | 20:17h | UTCPneumonia as a cardiovascular disease – Respirology (free)
Source: Critical Care Reviews Newsletter
Practical outpatient pharmacotherapy for alcohol use disorder
8 Mar, 2018 | 20:17h | UTCPractical outpatient pharmacotherapy for alcohol use disorder – Drugs in Context (free)
Review: Sleep problems during the menopausal transition
8 Mar, 2018 | 20:16h | UTC
Balanced Crystalloids vs Saline in Hospitalized Patients
2 Mar, 2018 | 02:10h | UTCBalanced Crystalloids versus Saline in Critically Ill Adults – New England Journal of Medicine (free)
Related article: Balanced Crystalloids versus Saline in Noncritically Ill Adults – New England Journal of Medicine (free)
Commentary: Balanced Crystalloids May Be Better Than Saline for Critically Ill Patients – NEJM Physician’s First Watch (free)
“Balanced crystalloids may be superior to saline in critically ill patients — but not in patients hospitalized outside an ICU” (from Physician’s First Watch)
Hydrocortisone plus Fludrocortisone Reduces Deaths in Septic Shock
2 Mar, 2018 | 02:08h | UTCHydrocortisone plus Fludrocortisone for Adults with Septic Shock – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Hydrocortisone-fludrocortisone cuts deaths in septic shock – The Hospitalist (free)
ACG Clinical Guideline: Alcoholic Liver Disease
2 Mar, 2018 | 02:05h | UTCACG Clinical Guideline: Alcoholic Liver Disease – The American Journal of Gastroenterology (free)
Commentary and summary: New Guideline for Management of Alcoholic Liver Disease – NEJM Journal Watch (free for a limited period)
Clinical Practice Guidelines for the Management of Hemorrhoids
2 Mar, 2018 | 02:07h | UTCRelated guideline: ACG Clinical Guideline: Management of Benign Anorectal Disorders – The American Journal of Gastroenterology (free)
Research: Impact of treatment delay on mortality in ST-segment elevation myocardial infarction (STEMI)
2 Mar, 2018 | 02:06h | UTCCommentaries: 3% rise in deaths for every 10 min delay in restoring blood flow after heart attack – OnMedica (free) AND Treatment Delay and Mortality in STEMI With Shock – American College of Cardiology, Latest in Cardiology (free)
Report: Tackling Multiple Unhealthy Risk Factors
2 Mar, 2018 | 02:02h | UTCPublic Health: Tackling multiple unhealthy risk factors: Emerging lessons from practice – The King’s Fund (free PDF)
Commentary: Multiple unhealthy risk factors: why they matter and how practice is changing (free)
See also: Summary (free PDF) AND Overview (free)
Guideline: Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy
2 Mar, 2018 | 02:04h | UTCRelated guidelines: Diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients: guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO) (free) AND Management of febrile neutropaenia: ESMO Clinical Practice Guidelines (free) AND Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: 2017 Update (free)