Internal Medicine
Guideline: Treatment of infections caused by multidrug-resistant Gram-negative bacteria
8 Mar, 2018 | 22:33h | UTCTreatment of infections caused by multidrug-resistant Gram-negative bacteria: report of the British Society for Antimicrobial Chemotherapy/Healthcare Infection Society/British Infection Association Joint Working Party – Journal of Antimicrobial Chemotherapy (free) (via @ABsteward)
Novel subgroups of adult-onset diabetes and their association with outcomes
8 Mar, 2018 | 22:29h | UTCNovel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: 5 Classifications of Diabetes Proposed – Physician’s First Watch (free) AND Should diabetes be divided into 5 categories to improve treatment? – Cardiovascular Business (free) AND Diabetes Consists of Five Types, Not Two, Say Researchers – Medscape (free registration required)
New Guide to Infection Control in The Hospital
8 Mar, 2018 | 22:31h | UTCNew Guide to Infection Control in The Hospital – International Society for Infectious Diseases (free)
A free, online resource on the principles and interventions needed to reduce healthcare associated infections, with suggested control measures across different resource levels.
Meta-Analysis: Drug treatment effects on outcomes in heart failure with preserved ejection fraction
8 Mar, 2018 | 22:30h | UTCEditorial: Pharmacological strategies in heart failure with preserved ejection fraction: time for an individualised treatment strategy? (free)
Commentary: Heartbeat: Is there any effective therapy for heart failure with preserved ejection fraction? (free)
In this meta-analysis of RCT testing treatments for patients with heart failure with preserved ejection fraction, only beta-blockers demonstrated reductions in all-cause and cardiovascular mortality.
Clinical Practice Guideline: Hoarseness
8 Mar, 2018 | 22:28h | UTCSee also: Executive Summary
2018 AHA/ASA Ischemic Stroke Updates
8 Mar, 2018 | 22:26h | UTCSummary for ED-relevant care: 2018 AHA/ASA Ischemic Stroke Updates – emDocs (free)
Original guideline: 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association (free PDF)
Research: Fluoroquinolone use and risk of aortic aneurysm and dissection
8 Mar, 2018 | 22:17h | UTCFluoroquinolone use and risk of aortic aneurysm and dissection: nationwide cohort study – The BMJ (free)
Related: Aortic Dissection and Aortic Aneurysms Associated with Fluoroquinolones: A Systematic Review and Meta-Analysis – American Journal of Medicine (free) AND Fluoroquinolones and collagen associated severe adverse events: a longitudinal cohort study – BMJ Open (free) AND Risk of Aortic Dissection and Aortic Aneurysm in Patients Taking Oral Fluoroquinolone – JAMA Internal Medicine (free)
Proton pump inhibition therapy and risk of oesophageal cancer
8 Mar, 2018 | 22:14h | UTCMaintenance proton pump inhibition therapy and risk of oesophageal cancer – Cancer Epidemiology (link to abstract – $ for full-text)
Commentary: Long-term PPI Use and Increased Esophageal CA Risk – Medscape (free registration required)
Related studies suggesting a link with gastric cancer: Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study – Gut (link to abstract – $ for full-text) AND Maintenance therapy with proton pump inhibitors and risk of gastric cancer: a nationwide population-based cohort study in Sweden – BMJ Open (free)
This observational study suggests a possible link.
ESC position paper on spontaneous coronary artery dissection
8 Mar, 2018 | 22:19h | UTCCommentary with key points to remember: European Position Paper on Spontaneous Coronary Artery Dissection – American College of Cardiology, Latest in Cardiology (free)
Related position statement: Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association – Circulation (free)
Self-Management of an Inferior ST-Segment Elevation Myocardial Infarction
8 Mar, 2018 | 22:15h | UTCCase report: Self-Management of an Inferior ST-Segment Elevation Myocardial Infarction – New England Journal of Medicine (free)
The Australian Rheumatology Association’s ‘top five’ list of investigations and interventions doctors and patients should question
8 Mar, 2018 | 22:12h | UTCEVOLVE: The Australian Rheumatology Association’s ‘top five’ list of investigations and interventions doctors and patients should question – Internal Medicine Journal (free) (via @RSiemieniuk)
See other lists of low-value practices in Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Another interesting list of commonly used low-value practices that should be questioned.
Research: Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality
8 Mar, 2018 | 22:07h | UTCEffect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: One-off PSA screening for prostate cancer does not save lives – eCancer News (free)
“Largest ever prostate cancer trial – CAP – published in the JAMA. No effect from low intensity PSA screening on prostate cancer mortality at 10 years”. (via @KariTikkinen see Tweet)
Inflammatory Bowel Disease Increases Likelihood of a Heart Attack
8 Mar, 2018 | 22:11h | UTCInflammatory Bowel Disease Increases Likelihood of a Heart Attack – American College of Cardiology (free) AND Inflammatory bowel disease may raise heart attack risk – Medical News Today (free) AND Those with IBD twice as likely to have heart attack – Cardiovascular Business (free)
Systematic review: Effectiveness of brief alcohol interventions in primary care populations
8 Mar, 2018 | 22:09h | UTCEffectiveness of brief alcohol interventions in primary care populations – Cochrane Library (free)
In general practice or emergency care settings, brief alcohol interventions can reduce alcohol consumption and related harm.
Guideline on choice of inotropic agent for patients with acute circulatory failure
8 Mar, 2018 | 22:08h | UTCSource: Critical Care Reviews Newsletter
Research: Effect of β‐Blockers Beyond 3 Years After Acute Myocardial Infarction
8 Mar, 2018 | 22:03h | UTCEffect of β‐Blockers Beyond 3 Years After Acute Myocardial Infarction – Journal of the American Heart Association (free for a limited period)
Related article: B-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction – Journal of The American College of Cardiology (free)
Cancer screening recommendations: an international comparison of high income countries
8 Mar, 2018 | 22:02h | UTCCancer screening recommendations: an international comparison of high income countries – Public Health Reviews (free) (via @hildabast see Tweet)
Systematic Review: Factor Xa inhibitors vs vitamin K antagonists in patients with atrial fibrillation
8 Mar, 2018 | 22:04h | UTCFactor Xa inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in patients with atrial fibrillation – Cochrane Library (free)
When available, Factor Xa inhibitors seems to be a better choice for treating these patients.
Digoxin and Mortality in Patients With Atrial Fibrillation
8 Mar, 2018 | 21:42h | UTCDigoxin and Mortality in Patients With Atrial Fibrillation – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Digoxin and Mortality in Patients With Atrial Fibrillation – American College of Cardiology, Latest in Cardiology (free) AND Digoxin Associated with Higher Mortality in Patients with Atrial Fibrillation – NEJM Physician’s First Watch (free)
Guideline: Cough Due to TB and Other Chronic Infections
8 Mar, 2018 | 21:40h | UTCCough Due to TB and Other Chronic Infections – CHEST Guideline and Expert Panel Report (free)
See also other recent CHEST guidelines on the management of cough in specific populations: Classification of Cough as a Symptom in Adults and Management Algorithms (free) AND Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold (free) AND Chronic Cough Due to Gastroesophageal Reflux in Adults (free) AND Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer (free) AND Cough in the athlete (free) AND Occupational and Environmental Contributions to Chronic Cough in Adults (free) AND Treatment of Unexplained Chronic Cough (free) AND Use of Management Pathways or Algorithms in Children With Chronic Cough (free) AND Management of Children With Chronic Wet Cough and Protracted Bacterial Bronchitis (free)
Scientific Statement: Obesity Management
8 Mar, 2018 | 21:40h | UTCThe Science of Obesity Management: An Endocrine Society Scientific Statement – Endocrine Reviews (free)
Commentary: Research Finds Little Difference Among Diet Plans’ Long-Term Effectiveness – Endocrine Society, via NewWise (free)
Guideline: Fluid therapy in neurointensive care patients
8 Mar, 2018 | 21:41h | UTCFluid therapy in neurointensive care patients: ESICM consensus and clinical practice recommendations – Intensive Care Medicine (free for a limited period) (via @luiscamacho02)
Position Paper: Frailty and the management of patients with acute cardiovascular disease
8 Mar, 2018 | 21:36h | UTC
Position Paper: Antithrombotic therapy and body mass
8 Mar, 2018 | 21:35h | UTC
Guideline: Management of opioid use disorders
8 Mar, 2018 | 21:34h | UTCManagement of opioid use disorders: a national clinical practice guideline – Canadian Medical Association Journal (free) (via @DavidJuurlink see Tweet)