Internal Medicine
Cohort study: childhood predictors of lung function trajectories and future COPD risk
12 Apr, 2018 | 02:04h | UTCChildhood predictors of lung function trajectories and future COPD risk: a prospective cohort study from the first to the sixth decade of life – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Related article: Lung function trajectories from pre-school age to adulthood and their associations with early life factors: a retrospective analysis of three population-based birth cohort studies – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentaries: Three-quarters of COPD cases are linked to childhood risk factors that are exacerbated in adulthood – The Lancet, via ScienceDaily (free) AND Early intervention may minimise later lung problems – The Melbourne Newsroom (free) AND COPD Risk Factors Evident Early in Life – NEJM Physician’s First Watch (free)
Cohort study: time for chronic dialysis initiation and mortality
12 Apr, 2018 | 02:11h | UTCDialysis Initiation and Mortality Among Older Veterans With Kidney Failure Treated in Medicare vs the Department of Veterans Affairs – JAMA Internal Medicine (free for a limited period)
Invited commentary: Appropriate Time for Chronic Dialysis Initiation: A Cause for Humility (free for a limited period)
Related articles: Treatment decisions for older adults with advanced chronic kidney disease – BMC Nephrology (free) AND Timing of Dialysis Initiation – What Has Changed Since IDEAL? – Seminars in Nephrology (free)
Perspective: many people taking antidepressants discover they cannot quit
12 Apr, 2018 | 02:01h | UTCMany People Taking Antidepressants Discover They Cannot Quit – The New York Times (10 articles per month are free)
Systematic review: alpha-blockers as medical expulsive therapy for ureteral stones
12 Apr, 2018 | 01:56h | UTCAlpha-blockers as medical expulsive therapy for ureteral stones – Cochrane Library (link to abstract – $ for full-text)
Summary: Alpha-blockers for ureteral stones in adult patients with symptoms of stone disease – Cochrane Library (free)
Evidence review: preventing type 2 diabetes in people with ‘prediabetes’ with diet and exercise
12 Apr, 2018 | 01:20h | UTC
Randomized controlled trial: physiotherapy education before abdominal surgery reduces lung complications
12 Apr, 2018 | 01:16h | UTCPhysiotherapy education before major abdominal surgery reduces lung complications – NIHR Signal (free)
See original article: Preoperative physiotherapy for the prevention of respiratory complications after upper abdominal surgery: pragmatic, double blinded, multicentre randomised controlled trial – The BMJ (free)
Summary: 2018 ESC guidelines for diagnosis and management of syncope
12 Apr, 2018 | 01:14h | UTCGuideline summaries: 2018 ESC Guidelines for Diagnosis and Management of Syncope – American College of Cardiology (free) AND Practical Instructions for the 2018 ESC Syncope Guidelines – American College of Cardiology (free)
Original Documents: 2018 ESC Guidelines for the diagnosis and management of syncope (free) AND Practical Instructions for the 2018 ESC Guidelines for the diagnosis and management of syncope (free)
Systematic review: percutaneous vertebroplasty for osteoporotic vertebral compression fracture
12 Apr, 2018 | 01:07h | UTCPercutaneous vertebroplasty for osteoporotic vertebral compression fracture – Cochrane Library (link to abstract – $ for full-text)
Summary: Featured Review: Vertebroplasty for treating spinal fractures due to osteoporosis – Cochrane Library (free)
“High quality evidence shows that vertebroplasty does not provide more clinically important benefits than placebo but may cause people harm”.
Consensus statement: improving the safety of opioid use for acute noncancer pain in hospitalized adults
12 Apr, 2018 | 00:55h | UTCCommentary: New guidance for safe opioid prescribing for hospitalized patients with acute pain – Beth Israel Deaconess Medical Center, via EurekAlert (free)
Randomized trial: talc administration by indwelling pleural catheter for malignant effusion
12 Apr, 2018 | 00:58h | UTCOutpatient Talc Administration by Indwelling Pleural Catheter for Malignant Effusion – New England Journal of Medicine (link to abstract – $ for full-text) (see Visual Abstract)
Commentary: Outpatient talc administration improves malignant effusion outcomes – Chest Physician (free)
Randomized trial: intensive statin therapy in high-risk diabetic patients
12 Apr, 2018 | 00:30h | UTCIntensive Treat-to-Target Statin Therapy in High-Risk Japanese Patients With Hypercholesterolemia and Diabetic Retinopathy: Report of a Randomized Study – Diabetes Care (link to abstract – $ for full-text)
Commentary: Intensive Statins in Diabetes Misses Primary Endpoint: EMPATHY – Medscape (free registration required)
Guideline: regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy
11 Apr, 2018 | 02:14h | UTC
Randomized trial: aminophylline for treatment of postdural puncture headache
12 Apr, 2018 | 00:31h | UTCAminophylline for treatment of postdural puncture headache: A randomized clinical trial – Neurology (link to abstract – $ for full-text)
Source: ACP Journal Wise ($)
Guideline: interventional spine and pain procedures in patients on antithrombotic medications
11 Apr, 2018 | 02:13h | UTC
Meta-analysis: nasal vs oronasal CPAP for OSA Treatment
11 Apr, 2018 | 02:11h | UTCMeta-analysis: Nasal vs Oronasal CPAP for OSA Treatment – CHEST (free)
Source: EvidenceAlerts
Review: management of patients with aortic valve stenosis
11 Apr, 2018 | 02:10h | UTCManagement of Patients With Aortic Valve Stenosis – Mayo Clinic Proceedings (free)
Cohort study: sleep deficiency and motor vehicle crash risk
11 Apr, 2018 | 02:07h | UTCCommentary: Sleep deficiency increases risk of a motor vehicle crash – Brigham and Women’s Hospital, via ScienceDaily (free)
“Study finds that sleep deficiency due to either sleep apnea or insufficient sleep duration is strongly associated with motor vehicle crashes, regardless of one’s self-reported sleepiness level” (from ScienceDaily)
Consensus statement: endovascular therapy of acute ischemic stroke
11 Apr, 2018 | 02:03h | UTCRelated guideline: 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association / American Stroke Association (free PDF)
Randomized controlled trial: acupuncture versus titrated morphine in acute renal colic
11 Apr, 2018 | 01:19h | UTCSource: EvidenceAlerts
Randomized controlled trial: preventive cognitive therapy for prevention of depressive recurrence
11 Apr, 2018 | 01:34h | UTCEffectiveness of preventive cognitive therapy while tapering antidepressants versus maintenance antidepressant treatment versus their combination in prevention of depressive relapse or recurrence (DRD study): a three-group, multicentre, randomised controlled trial – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentary: Preventive cognitive therapy is an effective alternative and addition to antidepressants for preventing depression relapse, study finds – ACP Internist (free) AND Preventive Cognitive Therapy Helps Limit Depression Recurrence – NEJM Physician’s First Watch (free) AND Depression: preventive cognitive therapy improves outcome in recurrent depression – Univadis (free registration required)
Perspective: some acutely ill patients are getting treated at home
6 Apr, 2018 | 01:49h | UTCHospitals are germy, noisy places. Some acutely ill patients are getting treated at home instead – The Washington Post (a few articles per month are free)
Source: STAT Newsletter
Richard Lehman’s journal reviews – 3 April 2018
6 Apr, 2018 | 01:44h | UTCRichard Lehman’s journal reviews, 3 April 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Perspective: ‘faith healing’ and chest pain
6 Apr, 2018 | 01:48h | UTCRelated: More Controversy Over Major Cardiology Clinical Trial – Cardiobrief (free) AND Cardiology World Erupts Into Controversy Over Change In Major Clinical Trial – Cardiobrief (free) AND Moving the Goalposts Into Unblinded Territory – Circulation: Cardiovascular Quality and Outcomes (free)
Meta-analysis: acute chest pain evaluation using coronary CT angiography
6 Apr, 2018 | 01:43h | UTCAcute chest pain evaluation using coronary computed tomography angiography compared with standard of care: a meta-analysis of randomised clinical trials – Heart (link to abstract – $ for full-text)
See commentary in: Articles of the month (March 2018) – First10EM (free)
Se related meta-analysis published recently with similar results: Outcomes of non-invasive diagnostic modalities for the detection of coronary artery disease: network meta-analysis of diagnostic randomised controlled trials – The BMJ (free)
“Bottom line: In the RCTs we have to date, CCTA demonstrate no benefit, but leads to an increase in unnecessary invasive procedures” (from First10EM).
Meta-analysis: migraine and the risk of cardiovascular and cerebrovascular events
6 Apr, 2018 | 01:41h | UTCCommentary: Migraines tied to higher risk for stroke, MI in large meta-analysis – Univadis (free registration required)


