Internal Medicine
Randomized Trial: Dual Antiplatelet Therapy in Acute Ischemic Stroke and High-Risk TIA
18 May, 2018 | 02:36h | UTCClopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA – New England Journal of Medicine (free)
Editorial: Antiplatelet Therapy after Ischemic Stroke or TIA (free)
Commentary: Dual Antiplatelet Therapy or Aspirin Alone After TIA or Minor Stroke? – NEJM Physician’s First Watch (free)
Clinical Guideline: Pharmacotherapy for Neuropathic Pain
18 May, 2018 | 02:33h | UTC
Guideline Summary: Cardio-Onco-Hematology in Clinical Practice
18 May, 2018 | 02:35h | UTCOriginal Guideline: Cardio-Onco-Hematology in Clinical Practice. Position Paper and Recommendations – Revista Espanola de Cardiologia (free)
Related Guidelines and Reviews: Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline (free) AND 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines (free) AND Canadian Cardiovascular Society Guidelines for Evaluation and Management of Cardiovascular Complications of Cancer Therapy (free) AND Cardiotoxicity of anticancer treatments: Epidemiology, detection, and management – CA: A Cancer Journal for Clinicians (free)
Systematic Review: Psychological Therapies for Treatment-resistant Depression in Adults
18 May, 2018 | 02:31h | UTCPsychological therapies for treatment-resistant depression in adults – Cochrane Library (free)
Summary: Are psychological therapies effective in treating depression that did not get better with previous treatment? – Cochrane Library (free)
Randomized Controlled Trial: Exercise Training Does Not Slow Dementia Progression
18 May, 2018 | 02:29h | UTCCommentaries: Exercise Doesn’t Slow Cognitive Decline in Patients with Dementia – NEJM Physician’s First Watch (free) AND Rigorous exercise does not halt dementia decline, study concludes – The Guardian (free) AND Expert reaction to effects of exercise on dementia in old people – Science Media Centre (free) AND Exercise ‘doesn’t slow’ progression of dementia – NHS Choices (free)
Randomized Controlled Trials: Treatments for Mild Asthma Compared
18 May, 2018 | 02:28h | UTCInhaled Combined Budesonide–Formoterol as Needed in Mild Asthma – New England Journal of Medicine (link to abstract – $ for full-text)
Quick Take Video Summary: Inhaled Combined Therapy as Needed in Mild Asthma (free)
Related Trial: As-Needed Budesonide–Formoterol versus Maintenance Budesonide in Mild Asthma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: International Study Suggests Alternative Treatment for Mild Asthma – McMaster University, via NewsWise (free) AND On Demand as Effective as Maintenance Therapy for Mild Asthma – Medscape (free registration required)
Review: Management of Acute Right Ventricle Failure
16 May, 2018 | 01:22h | UTCDiagnostic workup, etiologies and management of acute right ventricle failure – Intensive Care Medicine (free for a limited period)
Source: Critical Care Reviews Newsletter
Research: Amyloid PET Scan for Predicting Alzheimer’s Disease in Mild Cognitive Impairment
16 May, 2018 | 01:19h | UTCCommentaries: Biomarkers, PET imaging may predict cognitive decline en route to Alzheimer’s – Health Imaging (free) AND Amyloid PET Scan Can Predict Progression to Alzheimer’s in Patients With Mild Cognitive Impairment – MedicalResearch.com (free)
Related Studies: Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons (link to abstract and free commentaries) AND Identifying incipient dementia individuals using machine learning and amyloid imaging (free full-text and commentaries) AND High performance plasma amyloid-β biomarkers for Alzheimer’s disease (link to abstract and free commentaries)
Study: Visual Screening Tool Improves Prediction of Developing Dementia
16 May, 2018 | 01:18h | UTCImproving Prediction of Dementia in Primary Care – Annals of Family Medicine (free)
Commentaries: Screening Tool Improves Dementia Prediction – Medscape (free registration required) AND Visual Test Could Help Predict Dementia Risk in Elders – NEJM Physician’s First Watch (free)
Cohort Study: Colonoscopy Adenoma Findings and Long-term Colorectal Cancer Incidence
16 May, 2018 | 01:13h | UTCAssociation of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence – JAMA (free for a limited period)
Related Review: Optimizing post‐polypectomy surveillance: A practical guide for the endoscopist – Digestive Endoscopy (free) AND Optimal Colonoscopy Surveillance Interval after Polypectomy – Clinical Endoscopy (free)
Related Guidelines: Guidelines for Colonoscopy Surveillance After Screening and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer (free) AND Korean Guidelines for Postpolypectomy Colonoscopy Surveillance – Digestive Endoscopy (free) AND Colorectal cancer surveillance after index colonoscopy: Guidance from the Canadian Association of Gastroenterology (free) AND Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) Guideline (free)
Advanced adenomas seem to be associated with subsequent increased risk for colorectal cancer, but nonadvanced adenomas may not be associated with increased risk.
Richard Lehman’s Journal Review – 14 May 2018
16 May, 2018 | 01:04h | UTCRichard Lehman’s journal review, 14 May 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Guideline: Deprescribing Benzodiazepines
16 May, 2018 | 01:01h | UTCDeprescribing benzodiazepine receptor agonists – Canadian Family Physician (free) (via @Deprescribing)
Related: CaDeN Deprescribing Guidelines and Algorithms (free) AND 11 Drugs You Should Seriously Consider Deprescribing – Medscape Slideshow (free registration required) AND Current and future perspectives on the management of polypharmacy – BMC Family Practice (free)
Guideline: Screening for Impaired Vision in Adults Aged 65 years and Older
16 May, 2018 | 00:57h | UTCSee also: Summary of recommendations for clinicians and policy-makers (free)
Commentaries: Screening for impaired vision in older adults: New Canadian guideline – Canadian Medical Association Journal, via EurekAlert (free) Canadian Guideline Recommends Against Vision Screening of Older Adults in Primary Care Settings – NEJM Physician’s First Watch (free)
Viewpoint: Management Reasoning
16 May, 2018 | 00:55h | UTCManagement Reasoning: Beyond the Diagnosis – JAMA (free for a limited Period)
Meta-Analysis: Resistance Exercise for Depressive Symptoms
16 May, 2018 | 00:54h | UTCAssociation of Efficacy of Resistance Exercise Training With Depressive Symptoms: Meta-analysis and Meta-regression Analysis of Randomized Clinical Trials – JAMA Psychiatry (link to abstract – $ for full-text)
Commentaries: Resistance Exercise Might Improve Depression Symptoms – NEJM Physician’s First Watch (free) AND Resistance exercise may reduce depressive symptoms in adults – MedicalXpress (free) AND Resistance Exercise Training May Alleviate Some Depressive Symptoms – MedicalResearch.com (free)
Acute Pulmonary Embolism Review: Focus on the Clinical Picture
16 May, 2018 | 00:49h | UTCAcute Pulmonary Embolism: Focus on the Clinical Picture – Korean Circulatory Journal (free)
Source: Critical Care Reviews Newsletter
Opinion: Conflicting Evidence on Health Effects of Salt Reduction Calls for a Redesign of Guidelines
16 May, 2018 | 00:42h | UTC
Retrospective Cohort: Achieved Systolic BP and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus
16 May, 2018 | 00:35h | UTCEffect of Achieved Systolic Blood Pressure on Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus: A Population-Based Retrospective Cohort Study – Diabetes Care (link to abstract – $ for full-text)
Commentaries: Diabetics with lower achieved SBP may be at greater risk for cardiovascular disease – Cardiovascular Business (free) AND No reduced CVD risk for SBP <120 mm hg in type 2 diabetes – MedicalXpress (free)
AHA Advice for Patients: Are BP Measurement Mistakes Making You Chronically Ill?
15 May, 2018 | 12:37h | UTCAre blood pressure measurement mistakes making you chronically ill? – American Heart Association News (free text and infographic)
Commentary: BP measurement: you’re probably doing it wrong – Univadis (free registration required)
Randomized Trial: Restrictive vs. Liberal Fluids for Major Abdominal Surgery
15 May, 2018 | 05:05h | UTCEditorial: Finding the Right Balance (free)
Commentaries: Restrictive fluids tied to kidney injury after major abdominal surgery – MDedge (free) AND Restricting Fluids During Abdominal Surgery Shows No Benefit, Possible Renal Risk – Medscape (free registration required)
Short Review: Essential Tremor
14 May, 2018 | 05:51h | UTCClinical Pearl: Essential Tremor – NEJM Resident 360 (free)
EULAR Recommendations: Pain Management in Inflammatory Arthritis and Osteoarthritis
11 May, 2018 | 02:58h | UTCCommentary: EULAR Releases Recommendations for Pain Management in OA, Inflammatory Arthritis – Rheumatology Advisor (free)
AUA Guideline: Erectile Dysfunction
11 May, 2018 | 02:56h | UTCErectile Dysfunction – American Urology Association (2018) (free)
Randomized Trial: Outcomes in Atrial Fibrillation Ablation
11 May, 2018 | 02:53h | UTCCABANA: No Outcomes Benefit In First Big Trial Of AF Ablation – Cardiobrief (free)
Related Commentaries: Catheter ABlation vs ANtiarrhythmic Drug Therapy in Atrial Fibrillation – CABANA – American College of Cardiology (free) AND CABANA Misses Primary Endpoint, but Electrophysiologists See Support for Ablation – TCTMD (free)
Randomized Controlled Trial: High-Dose vs. Low-Dose Statin in Stable Coronary Artery Disease
10 May, 2018 | 17:55h | UTCWith a median follow-up of 3.9 years, high-dose as compared with low-dose pitavastatin significantly reduced the risk of the primary end point (4.3% vs 5.4%; NNT = 90), a composite of cardiovascular death, nonfatal myocardial infarction, nonfatal ischemic stroke, or unstable angina requiring emergency hospitalization.