Internal Medicine
Expert Analysis: Antiplatelet Therapy Beyond Aspirin in Patients With Stable Ischemic Heart Disease
15 Jun, 2018 | 01:06h | UTCAntiplatelet Therapy Beyond Aspirin in Patients With SIHD – American College of Cardiology (free)
Randomized Trial: Antipsychotic Treatment of Very Late-onset Schizophrenia-like Psychosis
15 Jun, 2018 | 00:55h | UTCCommentaries: Very late-onset schizophrenia-like psychosis: positive findings but questions remain unanswered – The Lancet Psychiatry (free) AND Low-Dose Antipsychotic Effective in Late-Onset Psychosis – Medscape (free registration required) AND Low-dose amisulpride effective for late-onset psychosis – Healio (free registration required)
Expert Consensus: Management of Adverse Effects of Antiplatelet Therapy for Acute Coronary Syndrome
7 Jun, 2018 | 23:33h | UTC
Randomized Trial: Aspirin Starting Five Days After Hip or Knee Arthroplasty for VTE Prophylaxis
7 Jun, 2018 | 23:29h | UTCSee Original Article: Aspirin or Rivaroxaban for VTE Prophylaxis after Hip or Knee Arthroplasty – New England Journal of Medicine (link to abstract – $ for full-text) AND Quick Take Video Summary: Preventing VTE after Hip or Knee Arthroplasty (free)
Systematic Review: Nicotine Replacement Therapy vs Control for Smoking Cessation
7 Jun, 2018 | 02:55h | UTCNicotine replacement therapy versus control for smoking cessation – Cochrane Library (free)
Summary: Can nicotine replacement therapy (NRT) help people quit smoking? – Cochrane Library (free)
Systematic Review: Interventions for Preventing Upper GI bleeding in the ICU
7 Jun, 2018 | 02:56h | UTCInterventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units – Cochrane Library (link to abstract – $ for full-text)
Summary: Interventions for preventing upper gastrointestinal bleeding in people on intensive care units – Cochrane Library (free)
Related Observational Study: H2 blockers prevented clinically important GI bleeding better than PPIs in ICU patients – ACP Hospitalist (free)
Review: Aspiration Pneumonia and Related Syndromes
7 Jun, 2018 | 02:54h | UTCAspiration Pneumonia and Related Syndromes – Mayo Clinic Proceedings (free)
Randomized Trial Continuous Low-dose Antibiotic Prophylaxis to Prevent UTI in Adults who Perform Clean Intermittent Self-catheterization
7 Jun, 2018 | 02:52h | UTC“The results of this large randomised trial, conducted in accordance with best practice, demonstrate clear benefit for antibiotic prophylaxis in terms of reducing the frequency of UTI for people carrying out CISC”.
Proof-of-concept Trial: Fecal Microbiota Transplantation for Primary Clostridium difficile Infection
7 Jun, 2018 | 02:50h | UTCCommentary: Antibiotics Weren’t Used to Cure These Patients. Fecal Bacteria Were – The New York Times (10 articles per month are free) AND The Latest Poop On Fecal Transplants Vs. Antibiotics For C. Difficile Diarrhea – Forbes (free)
Cohort Study: Metformin Safe for Many Patients with Chronic Kidney Disease
7 Jun, 2018 | 02:49h | UTCAssociation of Metformin Use With Risk of Lactic Acidosis Across the Range of Kidney Function: A Community-Based Cohort Study – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Study Supports Metformin Use at eGFRs as Low as 30 – NEJM Physician’s First Watch (free) AND Metformin safe for most diabetics with kidney disease – UPI (free) AND Evidence Growing Metformin Safe in Many With Diabetes and CKD – Medscape (free registration required)
Related Studies: Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease (link to abstract and commentaries) AND Metformin is linked to reduced mortality in type 2 diabetes with comorbid CKD and CHF – ACP Diabetes Monthly (free)
Review: Pulmonary Function Tests for the Generalist
7 Jun, 2018 | 02:45h | UTCPulmonary Function Tests for the Generalist: A Brief Review – Mayo Clinic Proceedings (free)
Research: New Risk Calculator Estimates Millions are Being Overtreated with Statins
7 Jun, 2018 | 02:42h | UTCClinical Implications of Revised Pooled Cohort Equations for Estimating Atherosclerotic Cardiovascular Disease Risk – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: New risk calculator could change the aspirin, statins, and blood pressure medications some people take – STAT (free) AND Statin recommendations may change, especially for African-Americans – CNN (free) AND Millions could have incorrect statin, aspirin and blood pressure prescriptions – Stanford Medicine, via ScienceDaily (free) AND Current models overestimate CVD risk of 11.8M US adults – Cardiovascular Business (free)
Highlights from the New GOLD COPD Guidelines
7 Jun, 2018 | 02:44h | UTCCatch up on new COPD guidelines – ACP Internist (free)
Original Guideline: 2018 Global Strategy for Prevention, Diagnosis and Management of COPD – Global Initiative for Chronic Obstructive Lung Disease (GOLD) (free PDF)
Pocket Guide: COPD Diagnosis, Management and Prevention (free PDF)
Systematic Review: Exercise for Cognitive Brain Health in Aging
7 Jun, 2018 | 02:43h | UTCExercise for cognitive brain health in aging: A systematic review for an evaluation of dose – Neurology Clinical Practice (link to abstract – $ for full-text)
Commentary: How Much Exercise Is Needed to Help Improve Thinking Skills? – American Academy of Neurology, via NewsWise (free) AND Exercise regimen can maintain cognition in older adults, researchers say – UPI (free) AND 1-Hour Exercise, 3 Times a Week Boosts Cognition in Older Adults – MedPage Today (free registration required)
Current Concepts in Diagnosis and Treatment of Functional Neurological Disorders
7 Jun, 2018 | 02:37h | UTCCurrent Concepts in Diagnosis and Treatment of Functional Neurological Disorders – JAMA Neurology (free for a limited period)
Canadian Guideline: Management of Chronic Hepatitis C
7 Jun, 2018 | 02:36h | UTCCommentaries: Hepatitis C guideline recommends screening for all people born 1945-1975 – CMAJ, via EurekAlert (free) AND Canadian Group Offers New Guidelines on Hepatitis C Screening, Management – NEJM Physician’s First Watch (free)
Related Guidelines: HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C – American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) (free) AND EASL Recommendations on Treatment of Hepatitis C 2018 – Journal of Hepatology (free)
Review: Optimal Pharmacological Therapy in ST-elevation Myocardial Infarction
7 Jun, 2018 | 02:34h | UTCSource: Critical Care Reviews Newsletter
Richard Lehman’s journal review – 4 June 2018
7 Jun, 2018 | 02:35h | UTCRichard Lehman’s journal review, 4 June 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Implementation Guide: Eliminating Inappropriate Telemetry Monitoring
7 Jun, 2018 | 02:33h | UTCEliminating Inappropriate Telemetry Monitoring: An Evidence-Based Implementation Guide – JAMA Internal Medicine (free for a limited period)
Invited Commentary: Continuing to Improve Appropriateness of Continuous Electrocardiographic Monitoring (Telemetry) (free for a limited period)
Cohort Study: A Simple Approach to Help Guide Diagnosis of Heart Failure with Preserved Ejection Fraction
6 Jun, 2018 | 21:51h | UTCA Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure with Preserved Ejection Fraction – Circulation (link to abstract – $ for full-text)
Commentary: H2FPEF Score for Diagnosis – American College of Cardiology (free)
Case-Control Study: Possible Association of Hydrochlorothiazide Use and Risk of Melanoma
6 Jun, 2018 | 21:53h | UTCAssociation of Hydrochlorothiazide Use and Risk of Malignant Melanoma – JAMA Internal Medicine (free)
Commentaries: Hydrochlorothiazide Associated with Melanoma Risk – NEJM Physician’s First Watch (free) AND Hydrochlorothiazide Tied to Increased Melanoma Risk – MedPage Today (free registration required)
This observational data suggests a possible association. Needs to be confirmed by other studies.
Opinion: Rush to Treat Non-alcoholic Fatty Liver Disease Causing More Harm than Good
6 Jun, 2018 | 21:45h | UTCRush to treat liver patients causing more harm than good – The University of Leeds (free) (via @PaulGlasziou)
Original article: Too much medicine: overdiagnosis and overtreatment of non-alcoholic fatty liver disease- The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Review: Management of Chronic Inflammatory Demyelinating Polyradiculoneuropathy
6 Jun, 2018 | 21:26h | UTC
Research: Venous Thromboembolism Prophylaxis Overused in Hospitalized Patients
6 Jun, 2018 | 21:25h | UTCUse of Venous Thromboembolism Prophylaxis in Hospitalized Patients – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Study: Hospitals Overuse VTE Prophylaxis – MedPage Today (free registration required) AND Excess venous thromboembolism prophylaxis common among low-, high-risk patients – Healio (free registration required) AND Venous Thromboembolism Prophylaxis Over & Underutilized in Some Hospitalized Patients – MedicalResearch.com (free)
Things We Do For No Reason: Neutropenic Diet
1 Jun, 2018 | 04:37h | UTCThings We Do For No Reason: Neutropenic Diet – Journal of Hospital Medicine (free) (via @guptaarjun90 and @AnilMakam)