Internal Medicine
Review: Ischemia and No Obstructive Coronary Artery Disease (INOCA): What Is the Risk
2 Sep, 2018 | 02:17h | UTC
Review: Hypertensive Disorders of Pregnancy and Future Maternal Cardiovascular Risk
2 Sep, 2018 | 02:17h | UTC
Study: Hospice Utilization in Heart Failure
2 Sep, 2018 | 02:14h | UTCTrends in Hospice Discharge and Relative Outcomes Among Medicare Patients in the Get With The Guidelines–Heart Failure Registry – JAMA Cardiology (free for a limited period)
Commentary: Hospice Underutilized in Heart Failure – NEJM Physician’s First Watch (free)
Guideline: Fecal Microbiota Transplant as Treatment for Clostridium Difficile Infection
2 Sep, 2018 | 02:15h | UTC
Palliative Care in Intensive Care Units: Why, Where, What, Who, When, How
2 Sep, 2018 | 02:13h | UTCPalliative care in intensive care units: why, where, what, who, when, how – BMC Anesthesiology (free)
Guideline: Periprocedural Antithrombotic Management for Lumbar Puncture
2 Sep, 2018 | 02:04h | UTC
Review: Risk Stratification on Pheochromocytoma and Paraganglioma from Laboratory and Clinical Medicine
2 Sep, 2018 | 02:06h | UTC
Review: The Broad Spectrum of Lung Diseases in Primary Antibody Deficiencies
2 Sep, 2018 | 01:53h | UTCThe broad spectrum of lung diseases in primary antibody deficiencies – European Respiratory Review (free)
Perspective: Type 2 Poliovirus Detection after Global Withdrawal of Trivalent Oral Vaccine
2 Sep, 2018 | 01:46h | UTC“Wild-type transmission of poliovirus is nearly halted. To eradicate poliomyelitis, cessation of vaccine-derived poliovirus transmission must also be addressed. Strategies to accomplish this are analyzed.” (via @NEJM see Tweet)
Randomized Trial: Partial Oral vs. Intravenous Antibiotic Treatment of Endocarditis
31 Aug, 2018 | 03:11h | UTCPartial Oral versus Intravenous Antibiotic Treatment of Endocarditis – New England Journal of Medicine (free for a limited period)
Commentaries: Partial Oral Treatment of Endocarditis – POET – American College of Cardiology (free) AND New treatment can halve hospital stays for some patients with heart infection – ESC Press Releases (free)
ESC/EACTS Guidelines on Myocardial Revascularization
31 Aug, 2018 | 03:09h | UTC2018 ESC/EACTS Guidelines on myocardial revascularization – European Heart Journal (free) (via @escardio see Tweet with Key Infographics)
ESC/ESH Guidelines for the Management of Arterial Hypertension
31 Aug, 2018 | 03:10h | UTC2018 ESC/ESH Guidelines for the management of arterial hypertension – European Heart Journal (free) (via @escardio see Tweet with Key Infographics)
Fourth Universal Definition of Myocardial Infarction
31 Aug, 2018 | 03:09h | UTCFourth universal definition of myocardial infarction (2018) – European Heart Journal (free) (via @escardio see Tweet with Key Infographics)
Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes
31 Aug, 2018 | 03:07h | UTCEffects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus – New England Journal of Medicine (free for a limited period)
Commentaries: Bleeds and benefit with aspirin balanced in patients with diabetes and no effect on cancer – ESC Press Releases (free) AND ASCEND: Aspirin Doesn’t Look Good for Primary CV Prevention in Diabetic Patients – TCTMD (free)
Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease
31 Aug, 2018 | 03:06h | UTCUse of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Aspirin Fails to Prevent CV Events in People at ‘Moderate’ Risk of Disease: ARRIVE – TCTMD (free) AND ARRIVE: New Findings Contribute to Growing Body of Evidence Surrounding Aspirin Use – American College of Cardiology (free) AND Daily Aspirin Fails to Lower CV Risk in Long-term, Primary Prevention ARRIVE Trial – Medscape (free registration required) AND Jury still out on aspirin a day to prevent heart attack and stroke – ESC Press Releases (free)
Position Statement: Recommendations for Participation in Competitive Sports of Athletes with Arterial Hypertension
31 Aug, 2018 | 03:03h | UTC
Meta-Analysis: Effectiveness of Interventions for Managing Multiple High-Burden Chronic Diseases in Older Adults
31 Aug, 2018 | 03:01h | UTCCommentaries: Care coordination improves health of older patients with multiple chronic diseases – CMAJ, via EurekAlert (free) AND Seniors healthier when medical care is coordinated – Reuters (free)
Related: Ten Recommendations: Designing a High-Performing Health Care System for Patients with Complex Needs (free Guidance and related perspectives) AND Multimorbidity: A Priority for Global Health Research (free research and commentaries)
A Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure with Preserved Ejection Fraction
31 Aug, 2018 | 03:00h | UTCA Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure With Preserved Ejection Fraction – Circulation (free) (via @CircAHA see Tweet with Infographic)
Editorial: H2FPEF Score: At Last, a Properly Validated Diagnostic Algorithm for Heart Failure With Preserved Ejection Fraction (free)
Randomized Trial: Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus
31 Aug, 2018 | 02:58h | UTCEffects of n−3 Fatty Acid Supplements in Diabetes Mellitus – New England Journal of Medicine (free for a limited period)
Commentaries: Fish oils do not prevent heart attack or strokes in people with diabetes – ESC News Releases (free) AND Omega-3 Fatty Acids Fail to Reduce CVD Events in Diabetic Patients: ASCEND – TCTMD (free)
Related Cochrane Review: Omega-3 fatty Acids for the Prevention of Cardiovascular Disease (link to abstract and commentaries)
Related Meta-Analysis: Omega-3 Fatty Acid Supplements Don’t Reduce Cardiovascular Risk (free study and commentary)
Guideline Synopsis: Diagnosis and Treatment of Clostridium difficile Infection
31 Aug, 2018 | 02:51h | UTCDiagnosis and Treatment of Clostridium difficile Infection – JAMA (free for a limited period) (via @ABsteward and @Abraham_RMI)
Original Guideline: Clinical Practice Guidelines for Clostridium difficileInfection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) – Clinical Infectious Diseases (free)
CHEST Guideline: Antithrombotic Therapy for Atrial Fibrillation
31 Aug, 2018 | 02:56h | UTCAntithrombotic Therapy for Atrial Fibrillation: CHEST Guideline and Expert Panel Report (free PDF)
News Release: The American College of Chest Physicians updates their antithrombotic therapy guidelines for patients with atrial fibrillation (free)
Randomized Trial: High-Sensitivity Troponin in the Evaluation of Suspected Acute Coronary Syndrome
31 Aug, 2018 | 02:49h | UTCCommentaries: Diagnosing myocardial infarction: a highly sensitive issue – The Lancet (free) AND Hs-TnI in Suspected ACS: High-STEACS Trial – American College of Cardiology (free) AND Is High Sensitivity Troponin Too Sensitive? – NEJM Journal Watch (free)
“Introduction of a high-sensitivity cardiac troponin I assay reclassified 1 in 6 patients with previously undetected myocardial necrosis, but did not lead to improved clinical outcomes in this large randomised trial” (via @chapdoc1 see Tweet)
“Very important study. What’s weird is that the “better” (more sensitive) troponin assays get, the less helpful the test becomes at the bedside. Look for a coming tsunami of iatrogenesis from overzealous evaluation of troponin bumps.” (via @drjohnm see Tweet)
Guideline: Management of Hypertensive Emergencies
31 Aug, 2018 | 02:45h | UTCESC Council on hypertension position document on the management of hypertensive emergencies – European Heart Journal – Cardiovascular Pharmacotherapy (free) (@Abraham_RMI)
“Patients that lack acute hypertension-mediated end organ damage to the heart, retina, brain, kidneys, or large arteries do not have a hypertensive emergency and can be treated with oral BP-lowering agents and usually discharged after a brief period of observation.”
Guideline: Management of Malignant Pleural Effusions
31 Aug, 2018 | 02:48h | UTCERS/EACTS statement on the management of malignant pleural effusions – European Respiratory Journal (free)
Evidence Review: Optimal Blood Pressure Target in Diabetic and Nondiabetic Hypertensive Patients
31 Aug, 2018 | 02:44h | UTCSee counterpoint suggesting lower BP targets: Sprinting Toward the Optimal Blood Pressure Target for Hypertensive Patients – Circulation Research (free)
“We have reviewed the randomized trial evidence in favor of a target blood pressure (BP) around 130/80 mm Hg in hypertensive patients with and without diabetes mellitus”