Internal Medicine
Review: Rare Thrombophilic Conditions
16 Oct, 2018 | 21:34h | UTCRare thrombophilic conditions – Annals of Translational Medicine (free)
Randomized Trial: Misoprostol Heals Small Bowel Ulcers in Aspirin Users With Small Bowel Bleeding
16 Oct, 2018 | 21:30h | UTCMisoprostol Heals Small Bowel Ulcers in Aspirin Users With Small Bowel Bleeding – Gastroenterology (free for a limited period)
Commentary: Misoprostol Helps Heal Small Bowel Ulcers – MedPage Today (free registration required)
Source: EvidenceAlerts
How to Prevent Brain-Sapping Delirium in the ICU
12 Oct, 2018 | 01:50h | UTCHow To Prevent Brain-Sapping Delirium In The ICU – NPR (free text and podcast)
Related: ABCDEF Bundle – Society of Critical Care Medicine (free resource) AND The ABCDEF Bundle: Science and Philosophy of How ICU Liberation Serves Patients and Families – Critical Care Medicine (free)
Review: What Treatments are Effective for Common Cold in Adults and Children?
12 Oct, 2018 | 01:51h | UTCWhat treatments are effective for common cold in adults and children? – The BMJ (free review and infographic)
Commentaries: What works for treating children’s colds? – BBC (free) AND Doctors should steer young children away from decongestants – OnMedica (free)
Review: A New Vaccine for Shingles
12 Oct, 2018 | 01:44h | UTCShingrix: A New Vaccine for Shingles – Therapeutics Initiative (free)
“Need to vaccinate 31 people to prevent one instance of HZ; Need to vaccinate 358 people to prevent one instance on post herpetic neuralgia” (via @amtejani)
Evidence-Based Analysis: Venous Thromboembolism Prophylaxis May Cause More Harm than Benefit
12 Oct, 2018 | 01:45h | UTCVenous thromboembolism prophylaxis may cause more harm than benefit: an evidence-based analysis of Canadian and international guidelines – Thrombosis Journal (free) (via @amtejani)
Cohort Study: Long-term Outcomes of Unrecognized MI
12 Oct, 2018 | 01:40h | UTCAssociation of Unrecognized Myocardial Infarction With Long-term Outcomes in Community-Dwelling Older Adults: The ICELAND MI Study – JAMA (free for a limited period)
Commentaries: Silent Infarcts Have Similar Mortality Over 10 Years as Clinically Recognized MI – TCTMD (free) AND Association of Unrecognized MI With Long-Term Outcomes – American College of Cardiology (free)
Related Study: Silent Myocardial Infarction and Long-Term Risk of Heart Failure (link to abstract and commentaries)
Early vs. Delayed Dialysis in Acute Kidney Injury
11 Oct, 2018 | 21:57h | UTCTiming of Renal-Replacement Therapy in Patients with Acute Kidney Injury and Sepsis – New England Journal of Medicine (link to abstract – $ for full-text)
Video Summary: Renal-Replacement Therapy for AKI (free)
Commentary: Is Kidney Dialysis Always Needed When Septic Shock Strikes? – HealthDay (free)
“Trial comparing early vs. delayed strategies of renal-replacement therapy in patients with early-stage septic shock who had severe acute kidney injury finds no significant between-group difference in overall mortality at 90 days.” (via @NEJM see Tweet)
Canadian Guideline for the Prevention and Management of Cardiovascular Disease in Primary Care
11 Oct, 2018 | 21:58h | UTC
Review: An Update on the Use of Inhaled Therapy in COPD
11 Oct, 2018 | 21:55h | UTCAn update on the use of inhaled therapy in COPD – Clinical Medicine (free)
Review: Management of Severe Acute Exacerbations of COPD
11 Oct, 2018 | 21:56h | UTC
Review: What is the Significance of Monoclonal Gammopathy of Undetermined Significance?
11 Oct, 2018 | 21:53h | UTCWhat is the significance of monoclonal gammopathy of undetermined significance? – Clinical Medicine (free)
Meta-Analysis: Evaluation of the Diet Wide Contribution to Serum Urate Levels
11 Oct, 2018 | 21:52h | UTCEditorial: The role of diet in serum urate concentration (free)
Commentary: Diet Might Play Less of a Role in Gout Than Previously Thought – Physician’s First Watch (free)
Randomized Trial: Community-Based Interventions to Improve Cardiovascular Risk in High-Risk Patients
11 Oct, 2018 | 21:48h | UTCEditorial: Of Barbershops and Churches: Can Community-Based Interventions Improve Cardiovascular Risk in High-Risk Patients? (free)
Commentaries: Faith-based approach to changing lifestyle lowers blood pressure – AHA Newsroom (free) AND How church communities can help lower African-Americans’ blood pressure – CNN (free) AND Church-Based Lifestyle Intervention Shows Promise for Lowering BP in Hypertensive African-Americans – TCTMD (free)
Related Study: Cluster-Randomized Trial of Blood-Pressure Reduction in Black Barbershops (free study and commentaries)
Committee Recommends New Restrictions on the use of Fluoroquinolones
11 Oct, 2018 | 21:47h | UTCCommentaries: EMA committee recommends restrictions on fluoroquinolone, quinolone antibiotics – Reuters (free) AND PRAC Recommends Restrictions on Fluoroquinolone, Quinolones – Medscape (free registration required)
Related FDA Safety Alert: Warnings for Fluoroquinolones on Risks of Mental Health and Low Blood Sugar Adverse Reactions (free statement and commentaries)
Position Paper: Non-Celiac Gluten/Wheat Sensitivity
11 Oct, 2018 | 21:46h | UTC
Review: Managing the Patient with Heart Failure in the ED
11 Oct, 2018 | 21:45h | UTCManaging the Patient with Heart Failure in the Emergency Department – European Heart Journal (free) (via @gonzaeperez)
Review: Office Approach to Small Fiber Neuropathy
11 Oct, 2018 | 21:43h | UTCOffice approach to small fiber neuropathy – Cleveland Clinic Journal of Medicine (free)
Infographic Series: Treatments and Initiatives that are Cost Effective
11 Oct, 2018 | 21:42h | UTCNine ways research could save the NHS money – NHS Dissemination Centre (free)
New infographic series with selected NIHR Signals covering a range of treatments and initiatives that are cost effective.
Review: Bicuspid Aortic Valve
11 Oct, 2018 | 21:42h | UTCBicuspid aortic valve: Basics and beyond – Cleveland Clinic Journal of Medicine (free)
ESPEN Guideline on Clinical Nutrition in the Intensive Care Unit
11 Oct, 2018 | 21:37h | UTCESPEN guideline on clinical nutrition in the intensive care unit – Clinical Nutrition (free)
Source: Critical Care Reviews Newsletter
Study: Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults
11 Oct, 2018 | 21:32h | UTCGenomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention – Journal of the American College of Cardiology (via @EricTopol)
Zackary Berger’s Journal Reviews – 8 October 2018
11 Oct, 2018 | 21:34h | UTCZackary Berger’s journal reviews, 8 October 2018 – The BMJ Opinion (free)
Zackary Berger reviews the latest research from the top medical journals.
Meta-Analysis: Statins Not Benefitial for Noncardiovascular Outcomes
11 Oct, 2018 | 21:31h | UTCStatins and Multiple Noncardiovascular Outcomes: Umbrella Review of Meta-analyses of Observational Studies and Randomized Controlled Trials – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Statin Benefits: Yes for CVD but No for Everything Else, Says New Review – TCTMD (free) AND Statins’ benefits beyond heart health aren’t clear-cut, analysis says – CNN (free)
New ADA Guideline: Management of Hyperglycemia in Type 2 Diabetes
11 Oct, 2018 | 20:13h | UTCCommentaries: New Consensus Report from the American Diabetes Association® (ADA) and the European Association for the Study of Diabetes (EASD) Calls for Paradigm Shift to Patient-Centered Care for Type 2 Diabetes – American Diabetes Association (free) AND New EASD-ADA consensus guidelines on managing hyperglycaemia in type 2 diabetes launched at EASD meeting – Diabetologia (free)
Related Guidelines: WHO Guideline: Medicines for the Treatment of Diabetes in Low-Resource Settings (free guideline and commentaries) AND Pharmacologic Glycemic Management of Type 2 Diabetes in Adults – Canadian Journal of Diabetes (free) ADA 2018 Standards of Medical Care in Diabetes (free guideline and commentaries) AND ACP Guideline: Hemoglobin A1c Targets for Glycemic Control in Type 2 Diabetes (free guideline and commentaries)