Internal Medicine
Meta-Analysis: Efficacy, Effectiveness, and Safety of Herpes Zoster Vaccines
26 Oct, 2018 | 02:42h | UTC“Using the adjuvant recombinant subunit vaccine might prevent more cases of herpes zoster than using the live attenuated vaccine, but the adjuvant recombinant subunit vaccine also carries a greater risk of adverse events at injection sites.”
Observational Study: Blood Pressure Levels and Outcomes in Patients With Diabetes Mellitus and Coronary Artery Disease
26 Oct, 2018 | 02:36h | UTCEditorial: The Ongoing Saga of Optimal Blood Pressure Level in Patients With Diabetes Mellitus and Coronary Artery Disease (free)
“A U‐shaped relationship between cardiovascular outcomes and BPs was observed.”
Observational Study: Blood Pressure Levels and Outcomes in Patients With Peripheral Artery Disease
26 Oct, 2018 | 02:33h | UTCEditorial: New Curveball for Hypertension Guidelines? Blood Pressure Targets in Peripheral Artery Disease (free)
“we found a higher rate of lower extremity PAD events with higher and lower SBP and pulse pressure and with lower DBP.”
Pulmonary Embolism: Contemporary Medical Management and Future Perspectives
26 Oct, 2018 | 02:32h | UTCReview: Pulmonary Embolism: Contemporary Medical Management and Future Perspectives – Annals of Vascular Disease (free PDF)
Meta-Analysis: Self-Monitoring of Blood Glucose Provides no Important Benefit for Most People with Type 2 Diabetes
26 Oct, 2018 | 02:30h | UTCOriginal Article: Self-monitoring blood glucose improves glycemic control in type 2 diabetes without intensive treatment: A systematic review and meta-analysis – Diabetes Research and Clinical Practice (link to abstract – $ for full-text)
Meta-Analysis: Cefazolin vs. Antistaphylococcal Penicillins for MSSA Bacteremia
26 Oct, 2018 | 02:27h | UTC
USPSTF Statement: Screening for Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults
26 Oct, 2018 | 02:28h | UTCEditorials: Challenges and Opportunities for Studying Routine Screening for Abuse (free) AND Addressing Intimate Partner Violence and Abuse of Older or Vulnerable Adults in the Health Care Setting—Beyond Screening (free)
Perspective: The Problem with Probiotics
26 Oct, 2018 | 02:08h | UTCThe Problem With Probiotics – The New York Times (free)
Related: Probiotic Safety—No Guarantees (free perspective)
“There are potential harms as well as benefits, and a lot of wishful thinking and imprecision in the marketing of products containing them.”
Study: Diagnosis of Pulmonary Embolism During Pregnancy
26 Oct, 2018 | 02:02h | UTCDiagnosis of Pulmonary Embolism During Pregnancy: A Multicenter Prospective Management Outcome Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Algorithm Rules Out Pulmonary Embolism in Pregnancy – NEJM Journal Watch (free) AND Algorithm Validated for Pulmonary Embolism Diagnosis in Pregnancy – MedPage Today (free registration required)
Randomized Trial: Antipsychotics Ineffective for Delirium in Intensive Care Patients
26 Oct, 2018 | 02:01h | UTCHaloperidol and Ziprasidone for Treatment of Delirium in Critical Illness – New England Journal of Medicine (free for a limited period)
Editorial: Dopamine Antagonists in ICU Delirium (free for a limited period)
Commentaries: Common use of antipsychotics shown ineffective for delirium in intensive care patients – NIH News Releases (free) AND Antipsychotic Drugs Don’t Ease ICU Delirium Or Dementia – NPR (free) AND Antipsychotics ineffective for treating ICU delirium – Vanderbilt University Medical Center (free)
Related Research: Effect of Haloperidol on Survival Among Critically Ill Adults With a High Risk of Delirium (free)
Order Wisely Video Lectures: Appropriate Use of Tests & Treatments
26 Oct, 2018 | 01:55h | UTCOrder Wisely®: Appropriate use of tests & treatments – High Value Practice Academic Alliance (free) (via @KariTikkinen)
Comprehensive educational program that reviews appropriate use of imaging exams, lab tests, medications, transfusions and procedures to promote high-value practice.
Podcast: HIV Care for the Internist
26 Oct, 2018 | 01:48h | UTC#121 HIV Care for the Internist – Curbsiders Internal Medicine Podcast (free audio and summary)
Alex Nowbar’s Research Reviews, 22 October 2018
26 Oct, 2018 | 01:47h | UTCAlex Nowbar’s research reviews—22 October 2018 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
Want to Keep Your Brain Sharp? Take Care of Your Eyes And Ears
26 Oct, 2018 | 01:46h | UTCWant To Keep Your Brain Sharp? Take Care Of Your Eyes And Ears – NPR (free)
Related Articles: Longitudinal Relationship Between Hearing Aid Use and Cognitive Function in Older Americans – Journal of the American Geriatrics Society (free) AND Cataract surgery and age-related cognitive decline: A 13-year follow-up of the English Longitudinal Study of Ageing – NPR (free)
Randomized Trial: Theophylline Not Effective at Reducing COPD Exacerbations
26 Oct, 2018 | 01:44h | UTCEffect of Theophylline as Adjunct to Inhaled Corticosteroids on Exacerbations in Patients With COPD: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentaries: TWICS results suggest no role for low-dose theophylline as add-on therapy in COPD – Medwire News (free) AND Low-Dose Theophylline Not Effective at Reducing COPD Exacerbations, Study Finds – AJMC (free)
Meta-Analysis: Enteral Nutrition Provided Within 48 hours After Admission in Severe Acute Pancreatitis
26 Oct, 2018 | 01:43h | UTC
Hospital Accreditation not Associated with Better Outcomes in Observational Study
26 Oct, 2018 | 01:42h | UTCCommentaries: Joint Commission accreditation doesn’t lead to better outcomes, study shows – Modern Healthcare (free) AND Doubt cast on value of hospital accreditation in Harvard study – Healthcare Dive (free)
Randomized Trial: Corticosteroid Injection vs. Night Splints for Carpal Tunnel Syndrome
26 Oct, 2018 | 01:40h | UTCInvited Commentary: Steroid injection or wrist splint for first-time carpal tunnel syndrome? (free)
“A single corticosteroid injection shows superior clinical effectiveness at 6 weeks compared with night-resting splints, making it the treatment of choice for rapid symptom response in mild or moderate carpal tunnel syndrome presenting in primary care.”
Report: Talking About Dying
26 Oct, 2018 | 01:39h | UTCNews Release: New report asks why doctors find it so hard to talk to patients about dying (free)
Commentaries: Doctors must talk ‘honestly’ to patients about dying – OnMedica (free) AND Doctors ‘need to start early conversation with patients about dying’ – BBC (free)
Eosinophilic Esophagitis: Review and Update
26 Oct, 2018 | 01:38h | UTCEosinophilic Esophagitis: Review and Update – Frontiers in Medicine (free)
Systematic Review: Prokinetics for Functional Dyspepsia
26 Oct, 2018 | 01:36h | UTCProkinetics for functional dyspepsia – Cochrane Library (free)
Summary: Medications which promote stomach movement to relieve upper abdominal discomfort that does not have a specific cause – Cochrane Library (free)
“we are unable to say whether prokinetics are effective for the treatment of functional dyspepsia.”
Cohort Study: Association of Cardiorespiratory Fitness With Long-term Mortality
26 Oct, 2018 | 01:35h | UTCCommentaries: Expansive New Study Says Not Exercising Is Worse for Your Health Than Smoking – TIME (free) AND Researchers show better cardiorespiratory fitness leads to longer life – MedicalXpress (free)
Cohort Study: Pre-Eclampsia and Risk of Dementia Later in Life
19 Oct, 2018 | 00:15h | UTCPre-eclampsia and risk of dementia later in life: nationwide cohort study – The BMJ (free)
Editorial: Pre-eclampsia and the brain (free)
Commentaries: Pre-eclampsia linked to raised risk of vascular dementia – OnMedica (free) AND Pre-eclampsia linked to an increased risk of dementia later in life – The BMJ (free)
Perspective: To Prevent Cardiovascular Disease, Pay Attention to Pregnancy Complications
19 Oct, 2018 | 00:14h | UTCTo Prevent Cardiovascular Disease, Pay Attention to Pregnancy Complications – JAMA (free for a limited period)
Related: Hypertensive Disorders of Pregnancy and Maternal Cardiovascular Disease (link to abstract and commentaries)
Review: Enhanced Recovery in Surgical Intensive Care
19 Oct, 2018 | 00:12h | UTCEnhanced Recovery in Surgical Intensive Care: A Review – Frontiers in Medicine (free)