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Internal Medicine

Ann Robinson’s Weekly Research Reviews, 5 November 2018

6 Nov, 2018 | 15:49h | UTC

Ann Robinson’s weekly research reviews, 5 November 2018 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 


Study: Antibiotic Prophylaxis and Incidence of Endocarditis

6 Nov, 2018 | 15:45h | UTC

Antibiotic Prophylaxis and Incidence of Endocarditis Before and After the 2007 AHA Recommendations – Journal of the American College of Cardiology (free)

Commentary: International study supports the use of antibiotic prophylaxis to prevent a life-threatening heart infection in high risk dental patients – contrary to NICE guidance that recommended against its use in the UK – The University of Sheffield (free)

 


Review: Causes and Prevention of Postoperative Myocardial Injury

6 Nov, 2018 | 15:43h | UTC

Causes and prevention of postoperative myocardial injury – European Journal of Preventive Cardiology (free)

 


Review: Update on Perioperative Acute Kidney Injury

6 Nov, 2018 | 15:42h | UTC

Update on Perioperative Acute Kidney Injury – Anesthesia & Analgesia (free)

 


Review: Lifestyle Modifications for Preventing and Treating Heart Failure

6 Nov, 2018 | 15:40h | UTC

Lifestyle Modifications for Preventing and Treating Heart Failure – Journal of the American College of Cardiology (free)

 


Study: Little Benefit in Screening Women Aged 55 with a Negative HPV DNA test

6 Nov, 2018 | 15:39h | UTC

Age at last screening and remaining lifetime risk of cervical cancer in older, unvaccinated, HPV-negative women: a modelling study – The Lancet Oncology (link to abstract – $ for full-text)

Commentaries: Study finds there may be little benefit in screening women aged 55 with a negative HPV DNA test – The Lancet (free) AND New test could mean cervical cancer screening could stop sooner – OnMedica (free) AND At What Age Can We Stop Screening for Cervical Cancer? – NEJM Journal Watch (free)

 


Review: Treatment of Lower Extremity Superficial Thrombophlebitis

6 Nov, 2018 | 15:34h | UTC

Treatment of Lower Extremity Superficial Thrombophlebitis – JAMA Clinical Evidence Synopsis (free for a limited period)

 


Perspective: Impact of the Discordance Between Blood Pressure Guidelines

5 Nov, 2018 | 12:12h | UTC

The Blood Pressure Landscape: Schism Among Guidelines, Confusion Among Physicians, and Anxiety Among Patients – Journal of the American College of Cardiology (free)

Commentary: Disagreements in Blood Pressure Guidelines Lead to Physician, Patient Confusion – Clinical Advisor (free) AND Competing hypertension guidelines: what’s a clinician to do? – Univadis (free registration required)

 


Deprescribing: The Fightback Against Polypharmacy Has Begun

5 Nov, 2018 | 12:11h | UTC

Deprescribing: the fightback against polypharmacy has begun – The Pharmaceutical Journal (free) (via @Deprescribing)

Related: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject) AND Deprescribing recommendations: An essential consideration for clinical guideline developers – Research in Social and Administrative Pharmacy (free)

 


Review: Acute Kidney Injury Definition and Diagnosis

6 Nov, 2018 | 15:04h | UTC

Acute Kidney Injury Definition and Diagnosis: A Narrative Review – Journal of Clinical Medicine (free)

 


Things We Do for No Reason: Acute Treatment of Hypertensive Urgency

5 Nov, 2018 | 12:08h | UTC

Acute Treatment of Hypertensive Urgency – Journal of Hospital Medicine (free PDF)

 


Systematic Review: Stroke Prevention in Patients With Atrial Fibrillation

5 Nov, 2018 | 12:05h | UTC

Stroke Prevention in Patients With Atrial Fibrillation: A Systematic Review Update – Agency for Healthcare Research and Quality (free)

Full Report: Stroke Prevention in Patients With Atrial Fibrillation: A Systematic Review Update (free PDF)

 


Review: Practical Approach to Diastolic Dysfunction in the Operating Room and the ICU

5 Nov, 2018 | 12:06h | UTC

Practical approach to diastolic dysfunction in light of the new guidelines and clinical applications in the operating room and in the intensive care – Annals of Intensive Care (free)

 


Randomized Trial: Effect of Digital Cognitive Behavioral Therapy for Insomnia

5 Nov, 2018 | 12:04h | UTC

Effect of Digital Cognitive Behavioral Therapy for Insomnia on Health, Psychological Well-being, and Sleep-Related Quality of Life: A Randomized Clinical Trial – JAMA Psychiatry (link to abstract – $ for full-text)

Commentaries: E-therapy may help ease insomnia – Reuters (free) AND Some Apps May Help Curb Insomnia, Others Just Put You To Sleep – NPR (free) AND Insomnia symptoms, overall health improve with online insomnia program – Northwestern University (free)

 


Update on Treatment of Immunoglobulin A Nephropathy

5 Nov, 2018 | 11:54h | UTC

Update on treatment of immunoglobulin A nephropathy – Nephrology (free)

 


Review: Management of Acute-On-Chronic Liver Failure

5 Nov, 2018 | 11:56h | UTC

Management of acute-on-chronic liver failure: an algorithmic approach – Hepatology International (free)

 


Carcinoid Syndrome: Update on the Pathophysiology and Treatment

5 Nov, 2018 | 11:53h | UTC

Carcinoid syndrome: update on the pathophysiology and treatment – Clinics (free)

 


Review: Cancer-Associated Thrombosis

5 Nov, 2018 | 11:51h | UTC

Cancer-Associated Thrombosis: An Overview of Mechanisms, Risk Factors, and Treatment – Cancers (free)

 


Acute Kidney Injury and Disease: Long‐Term Consequences and Management

5 Nov, 2018 | 11:49h | UTC

Acute kidney injury and disease: Long‐term consequences and management – Nephrology (free)

 


Meta-Analysis: Comparative Efficacy of Inhaled Medications for COPD

5 Nov, 2018 | 11:48h | UTC

Comparative efficacy of inhaled medications (ICS/LABA, LAMA, LAMA/LABA and SAMA) for COPD: a systematic review and network meta-analysis – International Journal of Chronic Obstructive Pulmonary Disease (free)

 


Randomized Trial: Gabapentin vs Pregabalin on Pain Intensity in Adults with Chronic Sciatica

5 Nov, 2018 | 11:42h | UTC

Effect of Gabapentin vs Pregabalin on Pain Intensity in Adults WIth Chronic Sciatica: A Randomized Clinical Trial – JAMA Neurology (link to abstract – $ for full-text)

Commentary: Chronic sciatica: gabapentin tops pregabalin as initial treatment – Univadis (free registration required)

 


NICE Antimicrobial Prescribing Guidelines

2 Nov, 2018 | 03:51h | UTC

Antimicrobial prescribing guidelines – National Institute for Health and Care Excellence (free resources)

Just Published Guidelines: Urinary tract infection (lower): antimicrobial prescribing (free) AND Urinary tract infection (recurrent): antimicrobial prescribing (free) AND Pyelonephritis (acute): antimicrobial prescribing (free) AND Prostatitis (acute): antimicrobial prescribing (free)

See also: Summary of antimicrobial prescribing guidance – managing common infections – National Institute for Health and Care Excellence (free PDF)

 


Meta-Analysis: Association of Sodium Intake and Major Cardiovascular Outcomes

2 Nov, 2018 | 03:49h | UTC

Association of sodium intake and major cardiovascular outcomes: a dose-response meta-analysis of prospective cohort studies – BMC Cardiovascular Disorders (free)

Related: Effects of Sodium and Potassium Intake on Chronic Disease Outcomes and Risks (free report and summary) AND Urinary Sodium Excretion, Blood Pressure, Cardiovascular Disease, and Mortality (link to abstract and commentaries) AND Salt intake and Cardiovascular Disease (free report and commentary)

 


Randomized Trial: Mirtazapine Added to SSRIs or SNRIs for Treatment Resistant Depression

2 Nov, 2018 | 03:43h | UTC

Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: phase III randomised placebo controlled trial (MIR) – The BMJ (free)

Commentary: Popular drug combination for treatment resistant depression is not more effective than a single antidepressant in primary care – University of Bristol (free)

 


Myocarditis in Adults: ED Presentations, Evaluation, and Management

2 Nov, 2018 | 03:40h | UTC

Myocarditis in Adults: ED Presentations, Evaluation, and Management – emDocs (free)

 


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