Internal Medicine
Guideline: Pharmacological Management of Osteoporosis in Postmenopausal Women
26 Mar, 2019 | 01:59h | UTCNews Release: Many postmenopausal women do not receive treatment for osteoporosis (free)
Commentary: Managing Osteoporosis in Postmenopausal Women: An Endocrine Society Guideline – Endocrinology Advisor (free)
See also: Point of Care Algorithm (free)
Thyrotoxicosis: Diagnosis and Management
26 Mar, 2019 | 01:43h | UTCThyrotoxicosis: Diagnosis and Management – Mayo Clinic Proceedings (free)
Related: Thyroid Storm: A Japanese Perspective (free study and commentary)
Less is More: A Clinical Overview of Off-label Use of Gabapentinoid Drugs
26 Mar, 2019 | 01:42h | UTCA Clinical Overview of Off-label Use of Gabapentinoid Drugs – JAMA Internal Medicine (free for a limited period)
Related Meta-Analysis: Anticonvulsants in the Treatment of Low Back Pain and Lumbar Radicular Pain (free study and commentaries)
“Clinicians who prescribe gabapentinoids off-label for pain should be aware of the limited evidence and should acknowledge to patients that potential benefits are uncertain for most off-label uses.”
Perspective: Why You Should Be a “Medical Conservative”
25 Mar, 2019 | 00:43h | UTCWhy you should be a “medical conservative” – Lown Institute (free)
Original Article: Perspective: The Case for Being a Medical Conservative (free article and twitter thread)
“being a medical conservative means being skeptical about new medical advances until unbiased and high-quality evidence shows a clear benefit”
Are the Risks of Drugs That Enhance Imaging Tests Overblown?
25 Mar, 2019 | 00:28h | UTCAre the Risks Of Drugs That Enhance Imaging Tests Overblown? – NPR (free)
Related: Meta-analysis: Acute Kidney Injury After Computed Tomography (link to abstract and commentaries) AND Reviews: Post-Contrast Acute Kidney Injury (free) AND Review: Does contrast cause kidney injury? (free)
Opinion – “Things We Do for No Reason: Neuroimaging for Hospitalized Patients with Delirium”
25 Mar, 2019 | 00:26h | UTCSee Complete Series of Things We Do For No Reason (free articles)
Opinion – “Things We Do for No Reason: Use of Antipsychotic Medications in Patients with Delirium”
25 Mar, 2019 | 00:24h | UTCSee Complete Series of Things We Do For No Reason (free articles)
Meta-Analysis: Anticoagulant Therapy for Acute Venous Thrombo-Embolism in Cancer Patients
24 Mar, 2019 | 20:44h | UTC
IDSA Guideline for the Management of Asymptomatic Bacteriuria
22 Mar, 2019 | 07:36h | UTCCommentaries: Bacteria in urine doesn’t always indicate infection – Infectious Diseases Society of America (free) AND Most Urinary Bacteria Do Not Require Antibiotics – MedicalResearch.com (free)
Systematic Review: Schedules for Self-monitoring Blood Pressure
22 Mar, 2019 | 07:34h | UTCSchedules for Self-monitoring Blood Pressure: A Systematic Review – American Journal of Hypertension (free)
“Home blood pressure should be measured for 3 days, increased to 7 only when mean blood pressure is close to a diagnostic or treatment threshold.”
Obesity Treatment, Beyond the Guidelines: Practical Suggestions for Clinical Practice
22 Mar, 2019 | 07:09h | UTCObesity Treatment, Beyond the Guidelines: Practical Suggestions for Clinical Practice – JAMA (free for a limited period)
Related: European Practical and Patient-Centred Guidelines for Adult Obesity Management in Primary Care – Obesity Facts (free)
WHO Consolidated Guidelines on Drug-resistant Tuberculosis Treatment
21 Mar, 2019 | 07:21h | UTCWHO consolidated guidelines on drug-resistant tuberculosis treatment – World Health Organization (free PDF)
News Release: New WHO recommendations to accelerate progress on TB – World Health Organization (free)
Meta-Analysis: Vitamin K for Reversal of Excessive Vitamin K Antagonist Anticoagulation
21 Mar, 2019 | 07:09h | UTCVitamin K for reversal of excessive vitamin K antagonist anticoagulation: a systematic review and meta-analysis – Blood Advances (free)
“Our findings indicate that patients on VKA therapy who have an INR between 4.5 and 10.0 without bleeding are not likely to benefit from vitamin K administration in addition to temporary VKA cessation.”
Cohort Study: Long-Term Consumption of Sugar-Sweetened and Artificially Sweetened Beverages and Risk of Mortality
21 Mar, 2019 | 06:30h | UTCCommentaries: ‘Just one sugary drink a day’ linked to health problems – NHS Choices (free) AND Sugary drinks linked to higher risk of premature death, especially for women, study says – CNN (free) AND Sugary drinks could raise risk of early deaths finds study – News Medical (free)
ASCO Guideline: Anticonvulsant Prophylaxis and Steroid Use in Adults with Metastatic Brain Tumors
20 Mar, 2019 | 03:36h | UTC
Large Observational Study Suggests High-Dose Nifedipine is Associated with Higher Cardiac Arrest Risk
20 Mar, 2019 | 03:29h | UTCPresented at the European Heart Rhythm Association 2019 Congress.
High-Dose Nifedipine Tied to Higher Cardiac Arrest Risk – TCTMD (free)
See also: Nifedipine linked with cardiac arrest – Pharmacy News (free) AND Common blood pressure drug may increase cardiac arrest risk – Medical News Today (free)
Randomized Trial: Comparison of Dual Therapies for Lowering Blood Pressure in Black Africans
20 Mar, 2019 | 03:33h | UTCPresented at the American College of Cardiology (ACC) 2019 Scientific Session.
Comparison of Dual Therapies for Lowering Blood Pressure in Black Africans – New England Journal of Medicine (free for a limited period)
Commentary: Two-Drug Combos Using Popular Calcium Channel Blocker Show Superiority in Lowering Blood Pressure – American College of Cardiology (free)
Diagnostic Test Interpretation: Evaluating the Erythrocyte Sedimentation Rate
20 Mar, 2019 | 03:25h | UTCEvaluating the Erythrocyte Sedimentation Rate – JAMA (free for a limited period)
Systematic Review: Outpatient Management of Fever and Neutropenia in Patients with Cancer
20 Mar, 2019 | 03:17h | UTCOutpatient treatment for people with cancer who develop a low‐risk febrile neutropaenic event – Cochrane Library (free)
Summary: Outpatient treatment for cancer patient with low-risk febrile neutropaenic event is effective – Cochrane Library (free)
Related Guideline: Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update – Journal of Clinical Oncology (free)
Guideline: Management of Asymptomatic Arrhythmias
19 Mar, 2019 | 03:40h | UTCPresented at the European Heart Rhythm Association 2019 Congress.
Randomized Trial: Early vs. Delayed Cardioversion in Recent-Onset Atrial Fibrillation
19 Mar, 2019 | 03:44h | UTCPresented at the European Heart Rhythm Association 2019 Congress.
Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation – New England Journal of Medicine (free for a limited period)
Editorial: The RACE to Treat Atrial Fibrillation in the Emergency Department (free for a limited period)
Commentary: For Acute A-fib, Wait-and-See Approach May Spare Many Patients from Cardioversion – TCTMD (free)
Related Commentary on Twitter
RACE 7 ACWAS: In patients presenting to the emergency department with recent-onset, symptomatic atrial fibrillation, a wait-and-see approach was noninferior to early cardioversion in achieving a return to sinus rhythm at 4 weeks. #EHRA2019 #Afib
— NEJM (@NEJM) March 18, 2019
Antimicrobial Prescription Guidelines in Critically Ill Immunocompromised Patients
19 Mar, 2019 | 03:20h | UTCSource: Critical Care Reviews Newsletter
Guidelines for Antibiotic Prescription in the Intensive Care Unit
19 Mar, 2019 | 03:24h | UTCSource: Critical Care Reviews Newsletter
Comprehensive guideline covering many common conditions in the Critical Care Unit.
Christopher Martyn’s research reviews – 18 March 2019
19 Mar, 2019 | 03:02h | UTCChristopher Martyn’s research reviews, 18 March 2019 – The BMJ Opinion (free)
British Guidelines on the Use of HIV Pre–exposure Prophylaxis (PrEP)
19 Mar, 2019 | 02:54h | UTCBHIVA/BASHH guidelines on the use of HIV pre–exposure prophylaxis (PrEP) 2018 – HIV Medicine (free)
Related guidelines: WHO implementation tool for pre-exposure prophylaxis of HIV infection – World Health Organization (free) AND Draft Recommendation Statement: Prevention of Human Immunodeficiency Virus (HIV) Infection: Pre-Exposure Prophylaxis – U.S. Preventive Services Task Force (free) AND Canadian guideline on HIV pre-exposure prophylaxis and nonoccupational postexposure prophylaxis – Canadian Medical Association Journal (free) AND Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine HIV pre-exposure prophylaxis: clinical guidelines. Update April 2018 – Journal of Virus Eradication (free) AND Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2017 Update: a Clinical Practice Guideline (free)