Internal Medicine
Study: Long-term Effects of Metformin on Diabetes Prevention
4 Apr, 2019 | 01:41h | UTCLong-term Effects of Metformin on Diabetes Prevention: Identification of Subgroups That Benefited Most in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study – Diabetes Care (free for a limited period)
Commentaries: Safe and Cheap Metformin Prevents Type 2 Diabetes Over 15 Years – Medscape (free registration required) AND Long-term metformin offsets diabetes in patients with higher glucose/HbA1c, history of gestational diabetes – MDedge (free)
WHO Guidelines on Tuberculosis Infection Prevention and Control
3 Apr, 2019 | 01:11h | UTCRelated Guidelines: WHO Consolidated Guidelines on Drug-resistant Tuberculosis Treatment (free) AND WHO Guideline: Latent TB Infection (free) AND WHO Guidelines for treatment of drug-susceptible tuberculosis and patient care (free)
Meta-analysis: Extended Anticoagulation for the Secondary Prevention of Venous Thromboembolic Events
3 Apr, 2019 | 00:53h | UTC
Ann Robinson’s Weekly Research Reviews – 2 April 2019
3 Apr, 2019 | 00:50h | UTCAnn Robinson’s weekly research reviews, 2 April 2019 – The BMJ Opinion (free)
Ann Robinson reviews the latest research from the top medical journals.
S2k Guidelines for Skin and Soft Tissue Infections
2 Apr, 2019 | 02:18h | UTCRelated Guidelines: Antibiotics after incision and drainage for uncomplicated skin abscesses: a clinical practice guideline – The BMJ (free text and infographics) AND Clinical Guidelines for the Antibiotic Treatment for Community-Acquired Skin and Soft Tissue Infection – Korean Society of Infectious Diseases and Korean Society for Chemotherapy (free) AND 2018 WSES/SIS-E consensus conference: recommendations for the management of skin and soft-tissue infections – World Journal of Emergency Surgery (free)
Portal Hypertension and Related Complications: Diagnosis and Management
2 Apr, 2019 | 01:57h | UTCPortal Hypertension and Related Complications: Diagnosis and Management – Mayo Clinic Proceedings (free)
Hypertension Management in Older and Frail Older Patients
2 Apr, 2019 | 01:51h | UTCHypertension Management in Older and Frail Older Patients – Circulation Research (free)
New EULAR Recommendations for the Management of Systemic Lupus Erythematosus
1 Apr, 2019 | 02:27h | UTCRelated Guidelines: Clinical Practice Guidelines for the Treatment of Systemic Lupus Erythematosus by the Mexican College of Rheumatology – Reumatología Clinica (free) AND The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults (free) AND First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus (free) AND Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus – The Journal of Rheumatology (free PDF)
Guideline: Optimization of the Treatment with Beta-lactam Antibiotics in Critically Ill Patients
1 Apr, 2019 | 02:22h | UTCRelated: Pharmacokinetics–pharmacodynamics issues relevant for the clinical use of beta-lactam antibiotics in critically ill patients – Critical Care (free) AND Extended antibiotic infusions could save lives: Here’s how to do it – PulmCCM (free) AND Mortality lower with prolonged vs. short-term IV infusion of antipseudomonal beta-lactams (link to abstract and commentary)
Guideline: Valproate Use in Women and Girls Of Childbearing Years
1 Apr, 2019 | 02:06h | UTCValproate Use In Women and Girls Of Childbearing Years (free PDF)
News Release: Thirteen UK healthcare bodies launch ‘pragmatic’ guidance on valproate use – Royal College of General Practitioners (free)
Commentary: New guidance on valproate use in women – OnMedica (free)
Review: Obesity Hypoventilation Syndrome
1 Apr, 2019 | 01:57h | UTCObesity Hypoventilation Syndrome – European Respiratory Review (free)
Related Review: Obesity hypoventilation syndrome: a current review – Jornal Brasileiro de Pneumologia (free)
Perspective: Screening for ‘Hidden’ Pancreatic Cancer Can Put People in Jeopardy
1 Apr, 2019 | 02:00h | UTCScreening for ‘hidden’ pancreatic cancer can put people in jeopardy – STAT (free)
Related: Overdiagnosis: Causes and Consequences in Primary Health Care (free reviews and opinions)
Meta-Analysis: Corticosteroids Increase Mortality in Patients with Influenza Pneumonia
29 Mar, 2019 | 07:51h | UTC
Meta-Analysis: Cefazolin vs. Anti-staphylococcal Penicillins for the Treatment of Staphylococcus aureus Bacteremia
29 Mar, 2019 | 07:47h | UTC
Systematic Review: Adverse Effects of Pharmacological Treatments of Major Depression in Older Adults
29 Mar, 2019 | 07:45h | UTCSee also: Full Report (free PDF) AND Evidence Summary (free PDF)
In-Hospital Cardiac Arrest: A Review
28 Mar, 2019 | 07:31h | UTCIn-Hospital Cardiac Arrest: A Review – JAMA (free for a limited period)
Meta-Analysis: Adenosine Deaminase for Diagnosis of Tuberculous Pleural Effusion
28 Mar, 2019 | 07:21h | UTC
Omega-3 Supplements Do Not Reduce the Risk of Cancer or Cardiovascular Disease
28 Mar, 2019 | 07:24h | UTCOriginal Article: Randomized Trial: Marine n−3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer (free)
Related Meta-Analysis: Omega-3 Fatty Acid Supplements Don’t Reduce Cardiovascular Risk (free article and commentary)
Related Systematic Review: Omega-3 fatty Acids for the Prevention of Cardiovascular Disease (free review and commentaries)
Study: Proton Pump Inhibitors and Risk of Acute and Chronic Kidney Disease
28 Mar, 2019 | 07:11h | UTCCommentary: Study: Research ties common heartburn medications to kidney disease and failure – University at Buffalo (free)
Related: Meta-Analysis of Observational Studies: Proton Pump Inhibitors are Associated with Increased Risk of Kidney Disease (link to abstract – $ for full-text) AND Proton Pump Inhibitors: Review of Emerging Concerns (free reviews) AND Deprescribing Proton Pump Inhibitors (free guidelines and reviews)
KDOQI US Commentary on the 2017 ACC/AHA Hypertension Guideline
27 Mar, 2019 | 06:22h | UTCKDOQI US Commentary on the 2017 ACC/AHA Hypertension Guideline – American Journal of Kidney Diseases (free)
Guideline for the Diagnosis and Management of Work-related Mental Health Conditions in General Practice
27 Mar, 2019 | 06:19h | UTCClinical guideline for the diagnosis and management of work-related mental health conditions in general practice – National Health and Medical Research Council, Australian Government (NHMRC) (free PDF)
See also: Short Form Guideline (free PDF) AND GP Summary (free PDF)
Commentary: Managing work-related mental health conditions in family medicine – Canadian Medical Association Journal (free for a limited period)
Related Commentary on Twitter
New guidance aims to support family physicians to help patients whose mental illness arises in the workplace: https://t.co/LomlqKC61J#familymedicine #primarycare #mentalhealth pic.twitter.com/sFN6ji2EHg
— CMAJ (@CMAJ) March 26, 2019
Alex Nowbar’s research reviews, 26 March 2019
27 Mar, 2019 | 05:53h | UTCAlex Nowbar’s research reviews, 26 March 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
Meta-Analysis: Lipid-lowering Agents in Older Individuals
27 Mar, 2019 | 05:52h | UTC
Evaluation of an Intervention to Reduce Low-Value Preoperative Care for Patients Undergoing Cataract Surgery
27 Mar, 2019 | 05:47h | UTCEvaluation of an Intervention to Reduce Low-Value Preoperative Care for Patients Undergoing Cataract Surgery at a Safety-Net Health System – JAMA Internal Medicine (free for a limited period)
Commentary: Cataract Surgery: QI Initiative Markedly Reduced Low-Value Preoperative Care – MedicalResearch.com (free)
Related: Systematic Review: Routine Preoperative Medical Testing for Cataract Surgery (free)
Things We Do for No Reason: Failing to Question a Penicillin Allergy History
27 Mar, 2019 | 05:41h | UTCSee Complete Series: Things We Do For No Reason (free articles)