Internal Medicine
Meta-Analysis: Duration of Dual Antiplatelet Therapy after Percutaneous Coronary Intervention with Drug-eluting Stent
30 Jun, 2019 | 17:52h | UTCRelated Randomized Trials: Shorter Duration of Dual Antiplatelet Therapy May be an Option for Patients Undergoing Percutaneous Coronary Intervention (free studies and commentaries)
IDSA Draft Lyme Disease Guidelines
30 Jun, 2019 | 17:48h | UTCIDSA/AAN/ACR Draft Lyme Disease Guidelines – Infectious Diseases Society of America (free PDF)
Commentary: New Draft Lyme Disease Guidelines Issued – NEJM Journal Watch (free)
A Practical Approach to Low-Dose Aspirin for Primary Prevention
30 Jun, 2019 | 17:49h | UTCA Practical Approach to Low-Dose Aspirin for Primary Prevention – JAMA (free for a limited period)
[Abstract Only] Randomized Trial: High Sodium Intake Increases the Risk of Bloating
30 Jun, 2019 | 17:45h | UTCEffects of the DASH Diet and Sodium Intake on Bloating: Results From the DASH–Sodium Trial – The American Journal of Gastroenterology (link to abstract – $ for full-text)
Commentary: Higher salt intake can cause gastrointestinal bloating – Johns Hopkins University Bloomberg School of Public Health (free)
Review: The Use of Activated Charcoal to Treat Intoxications
30 Jun, 2019 | 17:46h | UTCThe Use of Activated Charcoal to Treat Intoxications – Deutsches Arzteblatt International (free)
Update on Eosinophilic Granulomatosis with Polyangiitis
30 Jun, 2019 | 17:27h | UTCUpdate on eosinophilic granulomatosis with polyangiitis – Allergology International (free)
Related Guidelines: Eosinophilic granulomatosis with polyangiitis (Churg–Strauss) (EGPA) Consensus Task Force recommendations for evaluation and management – European Journal of Internal Medicine (free) AND EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis – Annals of Rheumatic Diseases (free) AND BSR and BHPR guideline for the management of adults with ANCA-associated vasculitis – Rheumatology (free)
Related Reviews: ANCA Glomerulonephritis and Vasculitis – Clinical Journal of the American Society of Nephrology (free) AND Pathogenetic and Clinical Aspects of Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitides – Frontiers in Immunology (free)
Guidelines for the Periprocedural Management of Thrombotic and Bleeding Risk in Patients Undergoing Percutaneous Image-Guided Interventions
30 Jun, 2019 | 17:15h | UTCPart II: Recommendations (free)
Serial High-Sensitivity Troponin Measurements to Estimate the Probability of Myocardial Infarction
28 Jun, 2019 | 07:45h | UTCApplication of High-Sensitivity Troponin in Suspected Myocardial Infarction – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: High-Sensitivity Troponin in Suspected MI – American College of Cardiology (free) AND Risk Stratification Using Serial High-Sensitivity Troponin Measurements – NEJM Journal Watch (free)
See also: Compass MI Calculator
Perspective: Challenging the Resistance to Palliative Care
28 Jun, 2019 | 07:42h | UTCSurvey Snapshot: Challenging the Resistance to “Palliative” – NEJM Catalyst (free)
Study Review: Antiretroviral Treatment can Reduce the Risk of HIV Transmission Between Male Partners to ‘Zero’
28 Jun, 2019 | 07:40h | UTCOriginal Study: Undetectable = Untransmittable: Risk of HIV Transmission in Serodifferent Gay Couples (free study and commentaries)
Related: Systematic Review: Negligible Risk of Transmitting HIV During Sex When Viral Load is Suppressed (free study and commentaries) AND UNAIDS Explainer: UNDETECTABLE = UNTRANSMITTABLE (free)
Study: Inpatient Physician Continuity Associated with Speedier Patient Discharge
28 Jun, 2019 | 07:38h | UTCCommentary: Inpatient physician continuity associated with speedier discharge at one hospital – ACP Hospitalist (free)
Randomized Trial: Amisulpride for the Rescue Treatment of Postoperative Nausea or Vomiting
27 Jun, 2019 | 09:25h | UTCRelated Study: Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Amisulpride as Treatment of Established Postoperative Nausea and Vomiting in Patients Who Have Had No Prior Prophylaxis (link to abstract)
Study: Antidepressants May Increase Suicide Risk
27 Jun, 2019 | 09:14h | UTCCommentary: New study: antidepressants significantly raise the risk of suicide in the treatment of depression for adults (free)
Observational Study Points to an Increased Risk of Diabetes Among Patients Using Statins
27 Jun, 2019 | 08:54h | UTCCommentaries: Statins may double the risk of type 2 diabetes – Medical News Today (free) AND Cholesterol Medication Could Invite Diabetes, Study Suggests – Ohio State University (free)
Related Studies: Another Observational Study Showing Association of Statin Use with Risk of New‐Onset Diabetes Mellitus (free study and commentaries) AND Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes (link to abstract and commentaries)
Did This Patient Have Cardiac Syncope? The Rational Clinical Examination Systematic Review
26 Jun, 2019 | 01:48h | UTCDid This Patient Have Cardiac Syncope? The Rational Clinical Examination Systematic Review – JAMA (free for a limited period)
Related Guidelines: 2018 ESC Guidelines for the diagnosis and management of syncope – European Heart Journal (free) AND 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (free)
Study: Discriminative Accuracy of FEV1:FVC Thresholds for COPD-Related Hospitalization and Mortality
26 Jun, 2019 | 02:24h | UTCDiscriminative Accuracy of FEV1:FVC Thresholds for COPD-Related Hospitalization and Mortality – JAMA (free for a limited period)
Commentary: Study funded by NIH supports optimal threshold for diagnosing COPD – NIH News Releases (free)
“These results support the use of FEV1:FVC less than 0.70 to identify individuals at risk of clinically significant COPD.”
Randomized Trials: Shorter Duration of Dual Antiplatelet Therapy May be an Option for Patients Undergoing Percutaneous Coronary Intervention
26 Jun, 2019 | 02:14h | UTCEffect of 1-Month Dual Antiplatelet Therapy Followed by Clopidogrel vs 12-Month Dual Antiplatelet Therapy on Cardiovascular and Bleeding Events in Patients Receiving PCI: The STOPDAPT-2 Randomized Clinical Trial – JAMA (free for a limited period)
Related Study: Effect of P2Y12 Inhibitor Monotherapy vs Dual Antiplatelet Therapy on Cardiovascular Events in Patients Undergoing Percutaneous Coronary Intervention: The SMART-CHOICE Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Dual Antiplatelet Therapy: Is It Time to Cut the Cord With Aspirin? (free for a limited period)
Audio Summary: Reducing the Intensity of Antithrombotic Therapy Following Coronary Stent Procedures (free)
Commentaries: Shorter Dual Antiplatelet Therapy May Be an Option for Patients Undergoing PCI – NEJM Journal Watch (free) AND Short and Optimal Duration of Dual Antiplatelet Therapy After Everolimus-Eluting Cobalt-Chromium Stent-2 – STOPDAPT-2 – American College of Cardiology (free)
Related Commentary on Twitter
Among patients undergoing PCI, aspirin and clopidogrel therapy (DAPT) for 1 vs 12 months resulted in a lower rate of CV and bleeding events, meeting criteria for both noninferiority and superiority https://t.co/OJ76qrEGiq
— JAMA (@JAMA_current) June 25, 2019
Choosing Wisely – Case Studies from the Top 10 Recommendations Across Campaigns
26 Jun, 2019 | 01:24h | UTCChoosing Wisely: Case Studies from the Top 10 Recommendations Across Campaigns – The Commonwealth Fund (free case studies)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Related Commentary on Twitter
ICYMI – the @commonwealthfnd released a series on #choosingwisely featuring 10 case studies of implementation of campaign recommendations in Canada, USA, Japan, Switzerland, New Zealand and Brazil ! Read all 10 cases here: https://t.co/nWj1EnSczd pic.twitter.com/c9IFgSEEzp
— Choosing Wisely Canada (@ChooseWiselyCA) June 25, 2019
Meta-Analysis: Incidence of New Onset Diabetes Mellitus Secondary to Acute Pancreatitis
26 Jun, 2019 | 01:07h | UTC
Alex Nowbar’s journal reviews – 25 June 2019
26 Jun, 2019 | 00:42h | UTCAlex Nowbar’s journal reviews, 25 June 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
Cohort Study: Cognitive Decline After Coronary Events
26 Jun, 2019 | 00:23h | UTCCommentaries: Cognitive decline may accelerate after heart attack, angina – American College of Cardiology (free) AND Ischemic Events Worsen Long-term Cognitive Decline – TCTMD (free) AND Heart problems may hasten cognitive decline – Reuters (free)
Study: Anticholinergic Drug Exposure and the Risk of Dementia
25 Jun, 2019 | 07:03h | UTCCommentaries: Preventing Alzheimer Disease by Deprescribing Anticholinergic Medications – JAMA Internal Medicine (free for a limited period) AND Commonly prescribed anticholinergic drugs linked to dementia risk – UPI (free) AND Expert reaction to anticholinergic drug exposure and risk of dementia – Science Media Centre (free) Commonly prescribed drugs are tied to nearly 50% higher dementia risk in older adults, study says – CNN (free)
Teachable Moment: Avoid Routine Testing for PT and/or INR, as Well as aPTT, in Patients Taking DOACs
25 Jun, 2019 | 06:54h | UTCCoagulation Testing in Patients Taking Direct Oral Anticoagulants: A Teachable Moment – JAMA Internal Medicine (free for a limited period)
Physiology and Pathophysiology of Potassium Homeostasis
25 Jun, 2019 | 06:31h | UTC
[Abstract Only] Meta-Analysis: Natural History of Adrenal Incidentalomas With and Without Mild Autonomous Cortisol Excess
25 Jun, 2019 | 06:33h | UTCNatural History of Adrenal Incidentalomas With and Without Mild Autonomous Cortisol Excess: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Incidentally discovered adrenal tumors rarely grow or affect hormonal function, review finds – ACP Internist (free) AND Healthcare guidelines should be updated for patients with certain adrenal tumors – University of Birmingham (free)
Related Guideline: Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors – European Journal of Endocrinology (free)