Internal Medicine
Podcast: Common Complete Blood Count (CBC) Abnormalities
28 Aug, 2019 | 02:13h | UTC#167 LIVE! Common CBC Abnormalities with Mary Kwok MD – The Curbsiders Internal Medicine Podcast (free)
Perspective: Why Doctors Still Offer Treatments That May Not Help
27 Aug, 2019 | 01:55h | UTCWhy Doctors Still Offer Treatments That May Not Help – The New York Times (10 articles per month are free)
Related: When Evidence Says No, But Doctors Say Yes – ProPublica (free) AND Meta-Research: A Comprehensive Review of Randomized Trials Leading to “Medical Reversals” in Three Medical Journals (free) AND 10 Medical Myths We Should Stop Believing. Doctors, Too. – The New York Times (10 articles per month are free)
Podcast: Diabetes Update
27 Aug, 2019 | 01:54h | UTC#168 Diabetes Update with Jeff Colburn MD – The Curbsiders Internal Medicine Podcast (free audio and summary)
Cohort Study: Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality
27 Aug, 2019 | 01:49h | UTCAssociation of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality – JAMA Internal Medicine (free for a limited period)
Commentary: More plant protein tied to longer life – Reuters (free)
Related Studies: Plant‐Based Diets Are Associated with a Lower Risk of Cardiovascular Disease and All‐Cause Mortality (free) AND Healthful and Unhealthful Plant-Based Diets and the Risk of Coronary Heart Disease (link to abstract and commentaries) AND Cohort Study: Fruit, vegetable, and legume intake, and cardiovascular disease and deaths (link to abstract and commentaries)
Study: Acute Gallbladder or Biliary Disease More Common in Patients Using Liraglutide
27 Aug, 2019 | 00:31h | UTCEffects of Liraglutide Compared With Placebo on Events of Acute Gallbladder or Biliary Disease in Patients With Type 2 Diabetes at High Risk for Cardiovascular Events in the LEADER Randomized Trial – Diabetes Care (free PDF for a limited period)
Commentary: Gallbladder, Biliary Tract Events Increased With Liraglutide – Medscape (free registration required)
Lazarus in Asystole: A Case Report of Autoresuscitation After Prolonged Cardiac Arrest
27 Aug, 2019 | 00:28h | UTC
Related Commentary on Twitter
**From the brink of death** Lazarus syndrome: spontaneous return of circulation after asystolic cardiac arrest https://t.co/v6U8HBqeuB@escardio @johncamm #openaccess #EHJCaseReports #ESCCoT #ESCardioEd #CardioTwitter pic.twitter.com/E2LmIwywGc
— European Society of Cardiology Journals (@ESC_Journals) August 24, 2019
[Abstract Only] Study: High Animal Protein Intake Linked to Increased Risk of Kidney Stones
27 Aug, 2019 | 00:26h | UTCPlant and Animal Protein Intakes and Risk of Incident Kidney Stones: Results from the Shanghai Men’s and Women’s Health Studies – Journal of Urology (link to abstract – $ for full-text)
Commentary: Kidney Stones Linked to High Animal Protein Intake – Renal & Urology News (free)
Related: NICE Guideline – Renal and Ureteric Stones: Assessment and Management (free guidelines on the subject) AND Fluid Intake and Dietary Factors and the Risk of Incident Kidney Stones in UK Biobank: A Population-based Prospective Cohort Study – European Urology Focus (free)
Cohort Study: Cardiovascular Manifestations of Systemic Sclerosis
27 Aug, 2019 | 00:19h | UTCRelated Guideline: Consensus best practice pathway of the UK Systemic Sclerosis Study group: management of cardiac disease in systemic sclerosis – Rheumatology (free)
Postoperative Management in Patients with Pheochromocytoma and Paraganglioma
27 Aug, 2019 | 00:13h | UTCPostoperative Management in Patients with Pheochromocytoma and Paraganglioma – Cancers (free)
Related Reviews: Current perioperative management of pheochromocytomas – Indian Journal of Urology (free) AND Surgical and Pharmacological Management of Functioning Pheochromocytoma and Paraganglioma – Paraganglioma: A Multidisciplinary Approach (free)
Study: High Blood Pressure in Adulthood Linked to Late-life Brain Structure Changes
25 Aug, 2019 | 21:32h | UTCCommentaries: Blood pressure control as an intervention to prevent dementia – The Lancet Neurology (free) AND Early blood pressure changes linked to poorer brain health – University College London (free) AND High blood pressure in mid-30s may pose risk to brain health – BBC (free) AND Blood pressure in our 30s and 40s has lasting impact on brain health – Medical News Today (free)
Related Study: Midlife to Late-Life Blood Pressure Patterns and Incident Dementia (link to abstract and commentaries)
Related Commentary on Twitter
Rising blood pressure in people as young as 36 is linked to markers of poorer brain health in later life, including blood vessel damage and brain shrinkage, finds a new study led by Prof Jonathan Schott @jmschott @UCLIoN @drcionucl @UKDRI @TheLancetNeuro https://t.co/fTZR8cdLlv
— UCL News (@uclnews) August 21, 2019
[Abstract Only] Observational Study Suggests Women with Heart Failure May Need Lower Doses of ACE Inhibitors or ARBs and β blockers than Men
25 Aug, 2019 | 21:31h | UTCIdentifying optimal doses of heart failure medications in men compared with women: a prospective, observational, cohort study – The Lancet (link to abstract – $ for full-text)
Related Commentary on Twitter
BIOSTAT-CHF trial (n=1,710) lowest mortality rates occurred at 100% of the recommended dose of ACEIs & β blockers for men, but women showed significant lower risk at 50% of the recommended doses with no further improvement at higher dose levels.https://t.co/OL2PIPl1aF
— Dr Rani Khatib FESC (@DrRaniKhatib) August 23, 2019
Mendelian Randomization Study: Genetically Determined Iron Status on Risk of Venous Thromboembolism and Carotid Atherosclerotic Disease
25 Aug, 2019 | 21:28h | UTC
Summary of ACIP/CDC Adult Immunization Updates
25 Aug, 2019 | 21:12h | UTCAdult Immunization Update – JAMA (free for a limited period)
See also: Recommended Adult Immunization Schedule for ages 19 years or older – Centers for Disease Control and Prevention (CDC) / Advisory Committee on Immunization Practices (ACIP) (free PDF)
Meta-Analysis: Any Level of Physical Activity Decreases Risk of Premature Death
25 Aug, 2019 | 21:05h | UTCEditorial: Every step you take – The BMJ (free)
Commentaries: “Sit less—move more and more often”: all physical activity is beneficial for longevity – The BMJ Opinion (free) AND ‘Sit less, move more’ may be key advice for living longer – NHS Choices (free) AND Every Little Step Helps – Any Physical Activity Linked to Decreased Mortality – MedicalResearch.com (free)
Optimal Management of Diabetic Foot Osteomyelitis
25 Aug, 2019 | 13:35h | UTCRelated: 2012 Infectious Diseases Society of America Clinical Practice Guideline for the Diagnosis and Treatment of Diabetic Foot Infections (free) AND Osteomyelitis in diabetic foot: A comprehensive overview – World Journal of Diabetes (free) AND Osteomyelitis in the diabetic foot – Diabetic Foot and Ankle (free) AND Diabetic foot – The BMJ (free) AND Diagnosis and Management of Diabetic Foot Complications – American Diabetes Association (free)
[Abstract Only] Randomized Trial: Effectiveness of Polypill for Primary and Secondary Prevention of Cardiovascular Diseases
23 Aug, 2019 | 08:48h | UTCEffectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial – The Lancet (link to abstract – $ for full-text)
Commentaries: 4-Drug Polypill Cuts CV Risk – NEJM Journal Watch (free) AND Four-in-one pill prevents third of heart problems – BBC (free)
Related: Clinical Impact of the Polypill for Cardiovascular Prevention in Latin America: A Consensus Statement of the Inter-American Society of Cardiology – Global Heart (free) AND Perspective: The Polypill and the Long Journey to Major Impact (opinion and reviews on the subject) AND Research: Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care (free commentaries)
Related Commentary on Twitter
NEW Research—Large five-year randomised trial supports use of #polypill to prevent #CVD: finding from PolyIran, a pragmatic, cluster-randomised trial #LancetCardiology #ESCCongress https://t.co/YtU4MBPWom pic.twitter.com/GocADDE7Kv
— The Lancet (@TheLancet) August 23, 2019
2019 ACR Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis
23 Aug, 2019 | 08:50h | UTCNews Release: Rheumatology and Spondylitis Organizations Release Updated Treatment Guideline for Axial Spondyloarthritis (free)
Related Guidelines: Spondyloarthritis in over 16s: diagnosis and management – NICE Updated Guideline (free) AND 2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis (free) Treating axial spondyloarthritis and peripheral spondyloarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force – Annals of Rheumatic Diseases (free) AND 2018 APLAR axial spondyloarthritis treatment recommendations – International Journal of Rheumatic Diseases (free)
Cohort Study: Association of Smoking Cessation With Subsequent Risk of Cardiovascular Disease
23 Aug, 2019 | 08:46h | UTCAssociation of Smoking Cessation With Subsequent Risk of Cardiovascular Disease – JAMA (free for a limited period)
Commentaries: Smoking Cessation and Reduction of Cardiovascular Disease Risk – JAMA (free for a limited period) AND Effects of smoking on the heart, blood vessels take at least a decade to fade – UPI (free)
Clinicians’ Guide to Cannabidiol and Hemp Oils
23 Aug, 2019 | 08:40h | UTCClinicians’ Guide to Cannabidiol and Hemp Oils – Mayo Clinic Proceedings (free)
Related: Guideline for Prescribing Medical Cannabinoids in Primary Care (free)
Systematic Review: Management of Glucose Control in Noncritically Ill, Hospitalized Patients Receiving Parenteral and/or Enteral Nutrition
23 Aug, 2019 | 08:34h | UTCRelated Guidelines: Diabetes Care in the Hospital: Standards of Medical Care in Diabetes—2019 – American Diabetes Association (free) AND In-Hospital Management of Diabetes – Diabetes Canada Clinical Practice Guidelines Expert Committee (free)
Related Reviews: Glucose Management in Hospitalized Patients – American Family Physician (free) AND Update on Glucose Management Among Noncritically Ill Patients Hospitalized on Medical and Surgical Wards – Journal of the Endocrine Society (free)
Redefining Medication Management in Dialysis: A Kidney Pharmacy Quality Pyramid
23 Aug, 2019 | 08:38h | UTCRedefining Medication Management in Dialysis: A Kidney Pharmacy Quality Pyramid – Kidney Medicine (free)
Related: Drug Management in the Elderly Adult With Chronic Kidney Disease: A Review for the Primary Care Physician – Mayo Clinic Proceedings (free) AND Medication Reconciliation and Therapy Management in Dialysis-Dependent Patients: Need for a Systematic Approach – Clinical Journal of the American Society of Nephrology (free)
Study: High Prevalence of Celiac Disease Among Screened First-Degree Relatives
23 Aug, 2019 | 08:33h | UTCHigh Prevalence of Celiac Disease Among Screened First-Degree Relatives – Mayo Clinic Proceedings (free for a limited period)
Commentary: Study calls for screening of all first-degree relatives of celiac disease patients – News Medical (free)
Alex Nowbar’s journal review—22 August 2019
23 Aug, 2019 | 08:36h | UTCAlex Nowbar’s journal review, 22 August 2019 – The BMJ Opinion (free)
Study: Risks of Specific Cardiovascular Diseases in Survivors of 20 Adult Cancers
22 Aug, 2019 | 11:03h | UTCCommentaries: Is it time to include cancer in cardiovascular risk prediction tools? – The Lancet (free) AND Cancer survivors likely to face increase in long-term risk of cardiovascular disease – London School of Hygiene and Tropical Medicine (free)
Related: AHA Statement: Cardio-Oncology Rehabilitation to Manage Cardiovascular Outcomes in Cancer Patients and Survivors (free guidelines) AND Practical Integration of the ASCO Guidelines for Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers (free guidelines)
Study: Presenting Symptoms in Men and Women Diagnosed With Myocardial Infarction
22 Aug, 2019 | 10:55h | UTCEditorial: Closing the Gap on Sex Disparity in Acute Coronary Syndrome: Is It Time to Reconsider Our Definitions of “Typical”? (free)
Commentary: Women more likely to have ‘typical’ heart attack symptoms than men – British Heart Foundation (free)