Internal Medicine
[Abstract Only] Cost-Effectiveness Analysis: High-Intensity Versus Low-Intensity Surveillance for Patients with Colorectal Adenomas
26 Sep, 2019 | 08:29h | UTCHigh-Intensity Versus Low-Intensity Surveillance for Patients With Colorectal Adenomas: A Cost-Effectiveness Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Model supports high-intensity surveillance after detection of colorectal adenomas – ACP Internist (free) AND High-intensity surveillance colonoscopy reduces CRC risk, is cost-effective for patients with colorectal adenomas – American College of Physicians (free)
Guideline Synopsis: Prevention and Management of Venous Thromboembolism
25 Sep, 2019 | 08:33h | UTCPrevention and Management of Venous Thromboembolism – JAMA (free for a limited period)
Clinical Review Audio: An Update on the Diagnosis and Treatment of Venous Thromboembolic Disease (free)
Original American Society of Hematology 2018 Guidelines: Prophylaxis for hospitalized and nonhospitalized medical patients (free) AND Diagnosis of venous thromboembolism (free) AND Optimal management of anticoagulation therapy (free) AND Treatment of pediatric venous thromboembolism (free) AND Venous thromboembolism in the context of pregnancy (free) AND Heparin-induced thrombocytopenia (free)
Position Paper: Withholding and Withdrawing Life-support in Adults in Emergency Care
25 Sep, 2019 | 08:31h | UTC
USPSTF Recommendation Statement: Screening for Asymptomatic Bacteriuria in Adults
25 Sep, 2019 | 08:35h | UTCEditorials: Updated Guidelines for Screening for Asymptomatic Bacteriuria (free) AND The 2019 USPSTF Report on Screening for Asymptomatic Bacteriuria—Lessons From History (free)
Author Interview: USPSTF Recommendation: Screening for Asymptomatic Bacteriuria in Adults (free audio)
Meta-Analysis: Effects of Antihypertensives, Lipid-modifying Drugs, Glycemic Control Drugs and Sodium Bicarbonate on the Progression of Chronic Kidney Disease
25 Sep, 2019 | 08:28h | UTC
Age to Stop? Appropriate Screening in Older Patients
25 Sep, 2019 | 08:25h | UTCAge to stop? Appropriate screening in older patients – Canadian Family Physician (free)
Editorial: Preventive care at both ends of life (free)
Podcast: Appropriate screening in older patients (free audio)
Source: Canadian Task Force on Preventive Health Care Newsletter
Perspective: Finding the Right Words to Stop Cancer Screening in Older Adults
25 Sep, 2019 | 08:18h | UTCFinding the Right Words to Stop Cancer Screening in Older Adults – JAMA (free)
Related Study: Older Adults’ Views and Communication Preferences About Cancer Screening Cessation – JAMA Internal Medicine (free)
Meta-analysis: Inherited Thrombophilia and the Risk of Arterial Ischemic Stroke
25 Sep, 2019 | 08:13h | UTC
Cohort Study: Preeclampsia and Cardiovascular Disease
25 Sep, 2019 | 08:09h | UTCPreeclampsia and Cardiovascular Disease in a Large UK Pregnancy Cohort of Linked Electronic Health Records: A CALIBER Study – Circulation (free for a limited period)
Commentary: Hypertension during pregnancy can increase later risk of heart disease – King’s College London (free)
Related: Cohort Study: Cardiovascular Disease After Hypertensive Disorders of Pregnancy Largely Explained by Conventional Cardiovascular Risk Factors (recent studies on the subject)
Consensus Recommendations for Ambulatory Blood Pressure Monitoring
24 Sep, 2019 | 08:26h | UTCRelated Reviews: Role of Ambulatory and Home Blood Pressure Monitoring in Clinical Practice: A Narrative Review – Annals of Internal Medicine (free) AND Ambulatory Blood Pressure Monitoring in Clinical Practice: A Review – American Journal of Medicine (free)
Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C Virus Infection in Chronic Kidney Disease: Synopsis of the KDIGO 2018 Clinical Practice Guideline
24 Sep, 2019 | 08:23h | UTCOriginal Guideline: KDIGO 2018 Clinical Practice Guideline for the Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C in Chronic Kidney Disease – Kidney International (free)
Podcast: Dominate Perioperative Medication Management
24 Sep, 2019 | 08:14h | UTC#174 Dominate Perioperative Medication Management – The Curbsiders Internal Medicine Podcast (free)
Related Episode: #135 Perioperative Medicine: Assess & Optimize Risk (free)
See also: Episode List
Guideline: Diagnosis of Chronic Anemia in Gastrointestinal Disorders
23 Sep, 2019 | 01:09h | UTC
Study: BMI, Diet, Alcohol and Diuretics Account for a Notable Proportion of Hyperuricemia Cases
23 Sep, 2019 | 01:05h | UTCCommentaries: Obesity, drinking and unhealthy diet add to gout risk – Reuters (free) AND Four Modifiable Risk Factors Tied to Hyperuricemia – HealthDay News (free)
Randomized Trial: Sertraline is Unlikely to Reduce Depressive Symptoms
23 Sep, 2019 | 01:06h | UTCCommentaries: Examining the antidepressant scattergun approach – The Lancet Psychiatry (free) AND Expert reaction to study on the clinical effectiveness of the antidepressant sertraline – Science Media Centre (free) AND Common antidepressant more effective for anxiety than depression – UPI (free) AND Antidepressants work, but just not how scientists thought they worked – The Conversation (free) AND Antidepressants may reduce anxiety more than depressive symptoms – University College London (free)
Related Commentary on Twitter (Thread – click for more)
Important new trial on the real-world effectiveness of antidepressants (sertraline) in primary care patients. Main finding: There is no evidence that antidepressants effectively treat depression symptoms in real-world patients (effect size: d<0.2) https://t.co/bq9atTwrdo
— Michael P. Hengartner, PhD (@HengartnerMP) September 20, 2019
[Abstract Only] Randomized Trial: Nicotine Patches Used in Combination with E-Cigarettes for Smoking Cessation
23 Sep, 2019 | 00:56h | UTCNicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation: a pragmatic, randomised trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary: Quick Take: Nicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation – 2 Minute Medicine (free)
Related: It’s safest to avoid e-cigarettes altogether – unless vaping is helping you quit smoking – The Conversation (free)
Related Commentary on Twitter
https://twitter.com/HealthEvMatters/status/1172072860598358016
ASCO Guideline: Management of Osteoporosis in Survivors of Adult Cancers with Nonmetastatic Disease
22 Sep, 2019 | 23:02h | UTC
Guideline: Diagnosis and Treatment of Low Back Pain
20 Sep, 2019 | 08:25h | UTCSource: Low back pain: joint guidelines from US Departments of Veterans Affairs, Defense – Univadis (free registration required)
Related: Clinical practice guidelines for the management of non-specific low back pain in primary care: an updated overview – European Spine Journal (free) AND Clinical practice guidelines for the noninvasive management of low back pain: A systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration – European Journal of Pain (free) AND Low back pain and sciatica in over 16s: assessment and management – NICE (free) AND Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians (free) AND National Clinical Guidelines for non-surgical treatment of patients with recent onset low back pain or lumbar radiculopathy – European Spine Journal (free)
[Abstract Only] Randomized Trial: SGLT2 Inhibitor Improves Outcomes in Patients with Heart Failure Even in the Absence of Diabetes
20 Sep, 2019 | 08:27h | UTCDapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction – New England Journal of Medicine (link to abstract – $ for full-text)
Related 2019 ESC Congress News Release, Before Publication: Randomized Trial: SGLT2 inhibitors Seems Beneficial for Heart Failure Even in Nondiabetics (free commentaries)
Commentaries: SGLT2 Inhibitor Dapagliflozin Lowers Risk for Worsening Heart Failure – NEJM Journal Watch (free) AND New research shows dapagliflozin used to treat diabetes can also treat heart failure, in patients with and without diabetes (the DAPA-HF Study) – Diabetologia (free)
Randomized Trial: No Difference in Major Cardiovascular Outcomes in Patients with Type 2 Diabetes Treated with DPP-4 Inhibitor vs. Sulfonylurea
20 Sep, 2019 | 08:15h | UTCEffect of Linagliptin vs Glimepiride on Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes: The CAROLINA Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Sulfonylureas and Cardiovascular Safety: The Final Verdict? – JAMA (free for a limited period)
Commentary: CAROLINA: No Added Heart Risk With Sulfonylureas – MedPage Today (free registration required)
Cohort Study: Early Palliative Care Linked to Increased Survival and Reduced Risk of Death in an Acute Care Setting Among Patients with Advanced Lung Cancer
20 Sep, 2019 | 08:21h | UTCAssociation of Early Palliative Care Use With Survival and Place of Death Among Patients With Advanced Lung Cancer Receiving Care in the Veterans Health Administration – JAMA Oncology (free for a limited period)
Editorial: Prolonged Survival With Palliative Care—It Is Possible, but Is It Necessary? (free)
Commentaries: Early Palliative Care Associated with Increased Survival in Lung Cancer Patients – MedicalResearch.com (free) AND Early palliative care for advanced lung cancer increases survival – Veterans Affairs Research Communications (free)
Related Systematic Review: Early palliative care for adults with advanced cancer – Cochrane Library (free summary and original article)
Related Guidelines: Integration of Palliative Care Into Standard Oncology Care: American Society of Clinical Oncology Clinical Practice Guideline Update (free) AND Consensus document of the Italian Association of Medical Oncology and the Italian Society of Palliative Care on early palliative care – Tumori Journal (free)
Related Video: Early Palliative Care: a video for health and care professionals – University of Edinburgh (free)
Related Randomized Trial: Early Palliative Care for Patients with Metastatic Non–Small-Cell Lung Cancer- New England Journal of Medicine (free)
Cohort Study: Metformin Linked to Reduced Risk of Cardiovascular Events Compared to Sulfonylurea Among Patients with Diabetes and Reduced Kidney Function
20 Sep, 2019 | 08:19h | UTCAssociation of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular Events Among Patients With Diabetes and Reduced Kidney Function – JAMA (free for a limited period)
Commentaries: Metformin Superior for Lowering CV Risk in Diabetics Who Progress to CKD – Renal & Urology News (free) AND Metformin Monotherapy Benefits Heart Even in Early CKD – MedPage Today (free registration required)
Related Commentary on Twitter
Monotherapy treatment with #metformin, compared with a #sulfonylurea, was associated with a lower risk of MACE among patients with diabetes and reduced kidney function https://t.co/Z1EZAjOOET
— JAMA (@JAMA_current) September 19, 2019
Cochrane Special Collection: Diagnosing Dementia
20 Sep, 2019 | 08:06h | UTCCochrane Special Collection: Diagnosing Dementia – Cochrane Library (free articles)
Commentary: Dementia diagnosis: a decade of evidence – Evidently Cochrane (free)
AAN Recommends People 65+ be Screened Yearly for Memory Problems
20 Sep, 2019 | 08:03h | UTCNews Release: AAN Recommends People 65+ be Screened Yearly for Memory Problems – American Academy of Neurology (free)
Original Recommendations: Quality improvement in neurology: Mild cognitive impairment quality measurement set – American Academy of Neurology (free PDF)
USPSTF Disagrees: USPSTF Draft Statement: Insufficient Evidence to Recommend Screening for Cognitive Impairment in Older Adults (free)
Less is More in Critical Care is Supported by Evidence-based Medicine
19 Sep, 2019 | 08:15h | UTCLess is more in critical care is supported by evidence-based medicine – Intensive Care Medicine (free for a limited period)
Related: Less is More: Ten Reasons for Considering to Discontinue Unproven Interventions (free commentaries)