Internal Medicine
Randomized Trial: Effect of Thoracoscopic Talc Poudrage vs. Talc Slurry via Chest Tube on Pleurodesis Failure Rate Among Patients With Malignant Pleural Effusions
6 Dec, 2019 | 10:21h | UTCEffect of Thoracoscopic Talc Poudrage vs Talc Slurry via Chest Tube on Pleurodesis Failure Rate Among Patients With Malignant Pleural Effusions: A Randomized Clinical Trial – JAMA (free for a limited period)
Related Commentary on Twitter
Among patients with malignant pleural effusion, there was no significant difference in the rate of pleurodesis failure between the use of talc poudrage and talc slurry https://t.co/AxWOdzvEnA
— JAMA (@JAMA_current) December 6, 2019
Ann Robinson’s research reviews—5 December 2019
6 Dec, 2019 | 08:38h | UTCAnn Robinson’s research reviews, 5 December 2019 – The BMJ Opinion (free)
Ann Robinson reviews the latest research from the top medical journals
Educational Review – Chest Imaging Using Signs, Symbols, and Naturalistic Images: A Practical Guide for Radiologists and Non-radiologists
6 Dec, 2019 | 08:42h | UTC
ASH Guideline: Prevention of Venous Thromboembolism in Surgical Hospitalized Patients
5 Dec, 2019 | 11:29h | UTCRelated: European guidelines on perioperative venous thromboembolism prophylaxis – European Journal of Anaesthesiology (comprehensive resource on the subject) AND American Society of Hematology 2018 Guidelines for Management of Venous Thromboembolism: Prophylaxis for Hospitalized and Nonhospitalized Medical Patients (free)
Consensus Statement on Fasting Before Procedural Sedation in Adults and Children
5 Dec, 2019 | 11:31h | UTCSee also (preoperative fasting guidelines): Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective Procedures: An Updated Report by the American Society of Anesthesiologists Task Force on Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration (free) AND Perioperative fasting in adults and children: guidelines from the European Society of Anaesthesiology (free) AND Clear fluids fasting for elective paediatric anaesthesia: The European Society of Anaesthesiology consensus statement – European Journal of Anaesthesiology (free) AND Canadian Pediatric Anesthesia Society statement on clear fluid fasting for elective pediatric anesthesia – Canadian Journal of Anesthesia (free)
Related Commentary on Twitter
🔐We are delighted to publish the first fasting and aspiration prevention recommendations specific to procedural sedation!
Join us for tonight's TweetChat at 7pm GMT!@SteveGreenMD @mgirwin @gandolfattoNV @LucyOsoyoos @RobackMark @dougcarlson1
🔗https://t.co/dTBLoCMU0A pic.twitter.com/XTDN98Fy9g
— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) December 3, 2019
Randomized Trial: Remote Ischemic Preconditioning May Have a Role in Reducing Myocardial Injury in Emergency Hip Fracture Surgery
5 Dec, 2019 | 11:07h | UTCRelated Perspective: Remote ischaemic preconditioning: an intervention for anaesthetists? – British Journal of Anaesthesia (free)
Related Commentary on Twitter
Remote ischaemic preconditioning reduced the risk of myocardial injury and infarction after emergency hip fracture surgery, finds new #BMJresearch https://t.co/Gb45BBpDEB
— The BMJ (@bmj_latest) December 4, 2019
ASH Guideline: Cardiopulmonary and Kidney Disease in Sickle Cell Disease
5 Dec, 2019 | 11:25h | UTC
ASH Guideline: Immune Thrombocytopenia
5 Dec, 2019 | 11:19h | UTCAmerican Society of Hematology 2019 guidelines for immune thrombocytopenia – Blood Advances (free)
Related: Consensus Report: Investigation and Management of Primary Immune Thrombocytopenia (guidelines and reviews on the subject)
Cohort Study: Maternal Diabetes During Pregnancy Linked to Early Onset of Cardiovascular Disease in Offspring
5 Dec, 2019 | 10:45h | UTCCommentaries: Link between diabetes in mothers and heart disease in children – OnMedica (free) AND Preventing and treating diabetes in women of childbearing age could reduce heart disease risk in the next generation – The BMJ Opinion (free)
Study: Smoking Cessation is Associated with Lower Disease Activity in Rheumatoid Arthritis Patients
5 Dec, 2019 | 10:34h | UTCCommentary: Smoking Cessation Lowers RA Disease Activity and CV Risks – RheumNow (free)
[Abstract Only] Cohort Study: Hair Dye and Chemical Straightener Associated with Increased Risk of Breast Cancer
5 Dec, 2019 | 07:49h | UTCHair dye and chemical straightener use and breast cancer risk in a large US population of black and white women – International Journal of Cancer (link to abstract – $ for full-text)
Commentaries: Permanent hair dye and straighteners may increase breast cancer risk – NIH News Releases (free) AND Hair Dyes And Straighteners Linked To Higher Cancer Risk, Especially For Black Women – NPR (free)
Systematic Review: Metformin for Prevention or Delay of Type 2 Diabetes Mellitus and Its Associated Complications
4 Dec, 2019 | 08:24h | UTCMetformin for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at increased risk for the development of type 2 diabetes mellitus – Cochrane Library (free)
Review: Celiac Disease
4 Dec, 2019 | 08:20h | UTCCeliac Disease – Mayo Clinic Proceedings (free)
Related Guidelines: European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten-related disorders (free) AND ACG Clinical Guidelines: Diagnosis and Management of Celiac Disease (free) AND Coeliac Disease: Recognition, Assessment and Management – NICE Guideline (free) AND European Society for Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2019 – Journal of Pediatric Gastroenterology and Nutrition (free PDF)
State of the Art: Management of Severe Acute Pancreatitis
3 Dec, 2019 | 01:38h | UTCManagement of severe acute pancreatitis – The BMJ (free for a limited period)
Related Guidelines: 2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery (free) AND American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)
Related Commentary on Twitter
The risks, measurements of severity, and management of severe acute pancreatitis and its complications have evolved rapidly over the past decade. What have we learnt from new evidence? #BMJEducation https://t.co/spDjWh8jRN
— The BMJ (@bmj_latest) December 2, 2019
Podcast: Managing Sarcopenia in Primary Care
3 Dec, 2019 | 01:32h | UTC#186 Sarcopenia: Raising the Bar in Primary Care – The Curbsiders Internal Medicine Podcast (free)
See also: Episode List
Position Statement: Antimicrobial De-escalation in Critically Ill Patients
1 Dec, 2019 | 22:06h | UTCRelated: Antibiotic de-escalation in the ICU: how is it best done? – Current Opinion in Infectious Diseases (free) AND Is de-escalation of antimicrobials effective? A systematic review and meta-analysis – International Journal of Infectious Diseases (free)
Alex Nowbar’s weekly review—29 November 2019
1 Dec, 2019 | 22:00h | UTCAlex Nowbar’s weekly review, 29 November 2019 – The BMJ Opinion (free)
Painless Visible Hematuria in Adults: An Algorithmic Approach Guiding Management
1 Dec, 2019 | 21:48h | UTCPainless Visible Haematuria in Adults: An Algorithmic Approach Guiding Management – Cureus (free)
Related Review: The Investigation of Hematuria – Deutsches Ärzteblatt international (free)
Systematic Review: Higher vs. Lower Fraction of Inspired Oxygen or Targets of Arterial Oxygenation for Adults Admitted to the Intensive Care Unit
29 Nov, 2019 | 08:32h | UTCHigher versus lower fraction of inspired oxygen or targets of arterial oxygenation for adults admitted to the intensive care unit – Cochrane Library (free)
Summary: Supplemental oxygen for adults admitted to the intensive care unit – Cochrane Library (free)
Related: Oxygen therapy for acutely ill medical patients: a clinical practice guideline – The BMJ (free) AND Oxygen Treatment in Intensive Care and Emergency Medicine – Deutsches Ärzteblatt International (free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary) AND A Systematic Review of the Effects of Hyperoxia in Acutely Ill Patients: Should We Aim for Less? – BioMed Research International (free) AND Things We Do For No Reason: Supplemental Oxygen for Patients without Hypoxemia – Journal of Hospital Medicine (free)
Meta-Analysis: The Clinical Efficacy and Safety of Vancomycin Loading Dose
29 Nov, 2019 | 08:09h | UTCRelated: Vancomycin Therapeutic Guidelines: A Summary of Consensus Recommendations from the Infectious Diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists – Clinical Infectious Diseases (free) AND Therapeutic drug monitoring of vancomycin: a guideline of the Division of Therapeutic Drug Monitoring, Chinese Pharmacological Society – Journal of Antimicrobial Therapy (free) AND Practice Guidelines for Therapeutic Drug Monitoring of Vancomycin: A Consensus Review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring – Journal of Infection and Chemotherapy (free PDF)
Post-extubation Dysphagia: A Problem Needing Multidisciplinary Efforts
29 Nov, 2019 | 07:55h | UTCPost-extubation dysphagia: a problem needing multidisciplinary efforts – Intensive Care Medicine (free for a limited period)
Related: Dysphagia in the intensive care unit: epidemiology, mechanisms, and clinical management – Critical Care (free)
Bridging Anticoagulation Therapy: A Teachable Moment
29 Nov, 2019 | 07:37h | UTCBridging Anticoagulation Therapy: A Teachable Moment – JAMA Internal Medicine (free for a limited period)
Related: 2017 ACC Expert Consensus Decision Pathway for Periprocedural Management of Anticoagulation in Patients With Nonvalvular Atrial Fibrillation (free) AND Bridging Anticoagulation: Primum Non Nocere – Journal of the American College of Cardiology (free) AND Periprocedural heparin bridging in patients receiving oral anticoagulation: a systematic review and meta-analysis – BMC Cardiovascular Disorders (free) AND Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation – New England Journal of Medicine (free)
Study: Proton Pump Inhibitors May be Associated with Increased the Risk of Viral Gastroenteritis
29 Nov, 2019 | 07:46h | UTCCommentaries: Further Evidence to Monitor Long-term Proton Pump Inhibitor Use – JAMA Network Open (free) AND Prescription antacids may increase risk for stomach infections – UPI (free)
[Abstract Only] Randomized Trial: Supplemental MRI Screening vs. Usual Care with Mammography Only for Women with Extremely Dense Breast Tissue
28 Nov, 2019 | 10:39h | UTCSupplemental MRI Screening for Women with Extremely Dense Breast Tissue – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Does MRI Screening Benefit Women With Extremely Dense Breasts? – U.S. News (free) AND Mixed Results With Mammo Plus MRI Screening – MedPage Today (free)
“The benefits need to be carefully weighed against the harms, as MRI examination is more expensive, and it requires the injection of a contrast agent into the body. MRI will also detect abnormalities that later turn out not to be breast cancer after all” (from U.S News)
Related Commentary on Twitter
In this randomized trial, women with extremely dense breast tissue were invited to undergo MRI screening or received only mammography during a 2-year screening period. https://t.co/tZmcappO00
— NEJM (@NEJM) November 27, 2019
[Abstract Only] New Strategy for Diagnosing Pulmonary Embolism with D-Dimer Adjusted to Clinical Probability Could Reduce the Use of Imaging Tests
28 Nov, 2019 | 10:41h | UTCDiagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Diagnosis of Pulmonary Embolism – American College of Cardiology (free)