Internal Medicine
[Abstract Only] Open-Label Randomized Trial: Oseltamivir vs. Usual Care for Influenza-like Illness in Primary Care
6 Jan, 2020 | 23:21h | UTCOseltamivir plus usual care versus usual care for influenza-like illness in primary care: an open-label, pragmatic, randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries (with conflicting opinions): Tamiflu, Cure-All – Emergency Literature of Note (free) AND Flu antiviral has bigger benefits for sicker, older patients – University of Oxford (free)
Related Systematic Reviews: Neuraminidase inhibitors for preventing and treating influenza in adults and children – Cochrane Library (free) AND Oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments – The BMJ (free) AND Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials – The Lancet (free registration required) AND Effectiveness of oseltamivir in adults: a meta-analysis of published and unpublished clinical trials – Family Practice (free)
Related Commentary on Twitter
New paper published in the Lancet found a moderate improvement in symptoms in pts treated with open label oseltamivir compared to usual care. Any one else find it curious it worked equally well in pts with and without confirmed influenza? https://t.co/KpBM1xMOTu pic.twitter.com/GcGi4yFBVO
— Rory Spiegel (@EMNerd_) January 3, 2020
Guideline: ADA 2020 Standards of Medical Care in Diabetes
25 Dec, 2019 | 21:43h | UTCJust published! New ADA 2021 Guideline for the Management of Diabetes
Guideline Homepage: ADA 2020 Standards of Medical Care in Diabetes – American Diabetes Association (free supplement)
Commentaries: ADA 2020 Standards of Care Incorporate CVD Risk Stratification, New Medications – Endocrinology Advisor (free) AND ADA releases 2020 standards of medical care in diabetes – University of North Carolina at Chapel Hill School of Medicine (free)
See also: Standards of Medical Care in Diabetes—2020 Abridged for Primary Care Providers – American Diabetes Association (free PDF) AND 2019 update to: Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) – Diabetologia (free)
See ADA 2020 Guideline topics below:
Introduction: Standards of Medical Care in Diabetes—2020
Summary of Revisions: Standards of Medical Care in Diabetes—2020
- Improving Care and Promoting Health in Populations: Standards of Medical Care in Diabetes—2020
- Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2020
- Prevention or Delay of Type 2 Diabetes: Standards of Medical Care in Diabetes—2020
- Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Medical Care in Diabetes—2020
- Facilitating Behavior Change and Well-being to Improve Health Outcomes: Standards of Medical Care in Diabetes—2020
- Glycemic Targets: Standards of Medical Care in Diabetes—2020
- Diabetes Technology: Standards of Medical Care in Diabetes—2020
- Obesity Management for the Treatment of Type 2 Diabetes: Standards of Medical Care in Diabetes—2020
- Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes—2020
- Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes—2020
- Microvascular Complications and Foot Care: Standards of Medical Care in Diabetes−2020
- Older Adults: Standards of Medical Care in Diabetes—2020
- Children and Adolescents: Standards of Medical Care in Diabetes−2020
- Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes—2020
- Diabetes Care in the Hospital: Standards of Medical Care in Diabetes—2020
Related Commentary on Twitter
ADA's "Standards of Medical Care in Diabetes—2020" is finally here! Featuring American Diabetes Association's latest clinical practice recommendations, the global standard for diabetes care. #ADASOC2020
READ NOW (OPEN ACCESS): https://t.co/CCArNKXi9D pic.twitter.com/Yj9gExpVdG
— ADA Professional Publications (@ADA_Pubs) December 20, 2019
[Abstract Only] Randomized Trial: Alcohol Abstinence Reduces Recurrence of Atrial Fibrillation
5 Jan, 2020 | 14:20h | UTCAlcohol Abstinence in Drinkers with Atrial Fibrillation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Cutting out alcohol may reduce atrial fibrillation episodes – Reuters (free) AND Atrial Fibrillation and Alcohol Abstinence – MedicalResearch.com (free) AND Alcohol Abstinence Linked to Lower Risk for Atrial Fibrillation Recurrence – NEJM Journal Watch (free)
Related Commentary on Twitter
Excessive alcohol consumption associated with AFib. Patients with paroxysmal or persistent AFib who were in sinus rhythm and who were consuming 10 or more drinks per week were randomly assigned to either alcohol abstinence or continued drinking for 6 mos. https://t.co/LXU274pwsi
— NEJM (@NEJM) January 1, 2020
NICE Guideline: Acute Kidney Injury
5 Jan, 2020 | 14:22h | UTCRelated: Series: Acute Kidney Injury in the Intensive Care Unit – Intensive Care Medicine (free articles) AND Practical approach to detection and management of acute kidney injury in critically ill patient – Journal of Intensive Care (free) AND Sepsis associated acute kidney injury – The BMJ (free) AND Acute kidney injury from sepsis: current concepts, epidemiology, pathophysiology, prevention and treatment – Kidney International (free) AND Drug-induced acute kidney injury diverse mechanisms of tubular injury – Current Opinion in Critical Care (free)
Review: Perioperative Acute Kidney Injury
5 Jan, 2020 | 13:33h | UTCPerioperative Acute Kidney Injury – Anesthesiology (free)
Related Review: Acute Kidney Injury: A frequently underestimated problem in perioperative medicine – Deutsches Ärzteblatt international (free)
Review: Vaccination of Adults in General Medical Practice
5 Jan, 2020 | 13:15h | UTCVaccination of Adults in General Medical Practice – Mayo Clinic Proceedings (free)
Related Immunization Tables: WHO recommendations for routine immunization – summary tables – World Health Organization (free) AND Recommended Adult Immunization Schedule for ages 19 years or older, United States, 2019 – Centers for Disease Control and Prevention (CDC) (free)
Management of Type 2 Diabetes in Developing Countries: Balancing Optimal Glycemic Control and Outcomes with Affordability and Accessibility to Treatment
5 Jan, 2020 | 13:12h | UTC
[Abstract Only] Cohort Study: NT-proBNP may Improve Cardiac Risk Prediction for Patients Undergoing Noncardiac Surgery
5 Jan, 2020 | 13:10h | UTCPreoperative N-Terminal Pro–B-Type Natriuretic Peptide and Cardiovascular Events After Noncardiac Surgery: A Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Preoperative levels of heart proteins may help predict death or cardiac complications in patients undergoing noncardiac surgery – American College of Physicians (free) AND Biomarker Predicts Perioperative Cardiovascular Complications – MedicalResearch.com (free) AND NT-proBNP May Hold the Key to Predicting Cardiac Risk Before Noncardiac Surgery – TCTMD (free) AND Preoperative NT-proBNP concentration may help improve perioperative risk estimation – 2 Minute Medicine (free)
Review: Perioperative Care of the Geriatric Patient for Noncardiac Surgery
13 Dec, 2019 | 10:18h | UTCPerioperative care of the geriatric patient for noncardiac surgery – Clinical Cardiology (free)
Related: Optimal Perioperative Management of the Geriatric Patient: A Best Practices Guideline from the American College of Surgeons NSQIP and the American Geriatrics Society (free) AND The Perioperative Care of Older Patients: Time for a New, Interdisciplinary Approach – Deutsches Ärzteblatt international (free) AND Peri‐operative optimisation of elderly and frail patients: a narrative review – Anaesthesia (free) AND Peri-operative care of the elderly 2014: Association of Anaesthetists of Great Britain and Ireland (free)
Meta-Analysis: Effectiveness of Management Strategies for Uninvestigated Dyspepsia
12 Dec, 2019 | 08:15h | UTCCommentary: Managing Dyspepsia with “Test and Treat” Ranked Best Strategy – NEJM Journal Watch (free)
Related Commentary on Twitter
#BMJResearch on the effectiveness of management strategies for uninvestigated dyspepsia found that testing for H pylori and eradication treatment in those who test positive ranked first but was not superior to other strategies @alex_ford12399 https://t.co/tmpbSCfjpc
— The BMJ (@bmj_latest) December 11, 2019
USPSTF Recommendation Statement: Screening for Abdominal Aortic Aneurysm
11 Dec, 2019 | 08:29h | UTCRecommendation Statement: Screening for Abdominal Aortic Aneurysm – US Preventive Services Task Force (free)
Evidence Report: Primary Care Screening for Abdominal Aortic Aneurysm – JAMA (free)
JAMA Editorials: Updated Guidelines on Screening for Abdominal Aortic Aneurysms (free) AND Updated US Preventive Services Task Force Recommendations for Abdominal Aortic Aneurysm—Are We Really Up To Date? (free) AND Screening for Abdominal Aortic Aneurysm—A Call to Arms? (free)
Author Interview: USPSTF Recommendation: Screening for Abdominal Aortic Aneurysm (free audio)
ESC Position Paper: Role and Safety of New Glucose‐lowering Drugs in Patients with Heart Failure
11 Dec, 2019 | 08:25h | UTC
Meta-Analysis Suggests Low Risk of Nephrogenic Systemic Fibrosis in Patients with Chronic Kidney Disease Receiving a Gadolinium-Based Contrast Agent
11 Dec, 2019 | 08:23h | UTCRisk of Nephrogenic Systemic Fibrosis in Patients With Stage 4 or 5 Chronic Kidney Disease Receiving a Group II Gadolinium-Based Contrast Agent: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)
Invited Commentary: Risk of Gadolinium-Based Contrast Agents in Chronic Kidney Disease—Is Zero Good Enough? – JAMA Internal Medicine (free for a limited period)
Hyperkalemia: Pathophysiology, Risk Factors and Consequence
11 Dec, 2019 | 08:14h | UTCHyperkalemia: pathophysiology, risk factors and consequences – Nephrology Dialysis Transplantation (free)
Related: Management of hyperkalemia in the acutely ill patient – Annals of Intensive Care (free) AND Acute Management of Hyperkalemia – Current Heart Failure Reports (free) AND Diagnosis and treatment of hyperkalemia – Cleveland Clinic Journal of Medicine (free) AND Potassium Disorders: Hypokalemia and Hyperkalemia – American Family Physician (free) AND Management of hyperkalemia in patients with kidney disease: a position paper endorsed by the Italian Society of Nephrology – Journal of Nephrology (free)
Source: Critical Care Reviews
AHA Scientific Statement: Managing Older Adults in the Cardiac Intensive Care Unit
10 Dec, 2019 | 08:41h | UTCNews Release: Treating more than just the heart is critical for geriatric patients – American Heart Association (free)
Infographics and Summaries of the New ACLS and PALS Updates
10 Dec, 2019 | 08:39h | UTCHomepage: CPR Guidelines (free summaries and infographics)
– 2019 Highlights – Guidelines Update for CPR & ECC
– 2019 FAQ – Guidelines Update for CPR & ECC
– 2019 Infographic – ACLS Guidelines Update
– 2019 Infographic – PALS Guidelines Update
Original Guidelines: AHA Updates on Advanced Cardiovascular Life Support (ACLS) (free) AND AHA Updates in Pediatric Life Support (free)
Related Commentary on Twitter
Have you seen the 2019 @American_Heart guidelines update? @sparsh717, @atolm6, @AylC1989 and @comilla_s have created #infographics to summarize the update! Here is the #ACLS update graphic!
AHA Update: https://t.co/Yo0kdKfZJM
ACLS Update infographic: https://t.co/Vb7R0LgAJI pic.twitter.com/tNadnBC2x5— CanadiEM (@WeAreCanadiEM) December 8, 2019
Consensus Report: Lung–kidney Interactions in Critically Ill Patients
10 Dec, 2019 | 08:36h | UTC
Review: Missed Vaccinations and Critical Care Admission
10 Dec, 2019 | 08:35h | UTC
Study: Even Light Alcohol Consumption Linked to Increased Cancer Risk
10 Dec, 2019 | 08:28h | UTCLight to moderate amount of lifetime alcohol consumption and risk of cancer in Japan – Cancer (free)
Commentaries: Even light alcohol consumption linked to higher cancer risk in Japan – Wiley (free)
Related: Alcohol and Cancer: A Statement of the American Society of Clinical Oncology (free Statement and commentaries) AND Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies – The Lancet (free study and commentaries)
Review: The Chaos of Hypertension Guidelines for Chronic Kidney Disease Patients
9 Dec, 2019 | 01:39h | UTCThe chaos of hypertension guidelines for chronic kidney disease patients – Clinical Kidney Journal (free)
Original Guidelines: Kidney Disease: Improving Global Outcomes Blood Pressure Work Group. KDIGO clinical practice guideline for the management of blood pressure in chronic kidney disease (free PDF) AND 2018 ESC/ESH Guidelines for the management of arterial hypertension (free) AND 2017 Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines (free)
Systematic Review: Corticosteroids for Treating Sepsis in Children and Adults
9 Dec, 2019 | 01:36h | UTCCorticosteroids for treating sepsis in children and adults – Cochrane Library (free)
Summary: Corticosteroids for treating sepsis – Cochrane Library (free)
Related: Adjunctive Corticosteroid Treatment in Septic Shock (review, guideline and meta-analysis on the subject)
The Ketogenic Diet: Pros and Cons
9 Dec, 2019 | 01:30h | UTCThe ketogenic diet: Pros and cons – Atherosclerosis (free for a limited period)
Related: Review of current evidence and clinical recommendations on the effects of low-carbohydrate and very-low-carbohydrate (including ketogenic) diets for the management of body weight and other cardiometabolic risk factors: A scientific statement from the National Lipid Association Nutrition and Lifestyle Task Force – Journal of Clinical Lipidology (free) AND Very-low-calorie ketogenic diet (VLCKD) in the management of metabolic diseases: systematic review and consensus statement from the Italian Society of Endocrinology (SIE) – Journal of Endocrinological Investigation (free) AND The Keto Diet Is Popular, but Is It Good for You? – The New York Times (10 articles per month are free)
Cognitive Symptoms of Alzheimer’s Disease: Clinical Management and Prevention
9 Dec, 2019 | 01:28h | UTCState of the Art Review: Cognitive symptoms of Alzheimer’s disease: clinical management and prevention – The BMJ (free for a limited period)
NICE Guideline: Menopause
6 Dec, 2019 | 10:50h | UTCMenopause: diagnosis and management – National Institute for Health and Care Excellence (free)
New ACR/EULAR Classification Criteria for IgG4‐Related Disease
6 Dec, 2019 | 10:26h | UTCCommentary: ACR and EULAR release new classification criteria for IgG4-related disease – American College of Rheumatology (free)