Internal Medicine
Potentially Inappropriate Prescribing in Dementia: A State-of-the-art Review
16 Jan, 2020 | 02:45h | UTCPotentially inappropriate prescribing in dementia: a state-of-the-art review since 2007 – BMJ Open (free)
Expert Statement: Clostridioides Difficile Infection in the Critically Ill
15 Jan, 2020 | 08:11h | UTCClostridioides difficile (formerly Clostridium difficile) infection in the critically ill: an expert statement – Intensive Care Medicine (free for a limited period)
Related: Clostridioides Difficile: Diagnosis and Treatments (free BMJ review and guidelines on the subject)
FDA Safety Communication: Possible Increased Risk of Cancer with Weight-loss Medicine Lorcaserin
15 Jan, 2020 | 08:02h | UTCCommentaries: CV Safety Trial for Lorcaserin Picks Up Cancer Signal: FDA – TCTMD (free) AND FDA Warning: Weight Loss Drug Belviq May Increase Cancer Risk- Forbes (free)
Randomized Trial: Effectiveness of Combined Behavioral and Drug Therapy for Overactive Bladder Symptoms in Men
15 Jan, 2020 | 08:07h | UTCEffectiveness of Combined Behavioral and Drug Therapy for Overactive Bladder Symptoms in Men: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
Commentaries: What Works Best to Help Men With Overactive Bladder? – HealthDay News (free) AND For Overactive Bladder in Men, Start with Behavioral Strategies – NEJM Journal Watch (free)
Related Commentary on Twitter
Behavioral therapy for overactive bladder in men as effective as 2-drug therapy, combination of the two not much better than either alone. Great opportunity for drug-sparing management. But, how many places offer this? https://t.co/057Zj65Tpk pic.twitter.com/oToxXxI8lI
— Mike Steinman (@MikeSteinman) January 14, 2020
[Abstract Only] Study: Physician Time Spent Using the Electronic Health Record During Outpatient Encounters
15 Jan, 2020 | 08:05h | UTCPhysician Time Spent Using the Electronic Health Record During Outpatient Encounters: A Descriptive Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Doctors average 16 minutes on the computer for every patient – Reuters (free) AND How Doctors May Be Spending More Time With Electronic Health Records Than Patients – Forbes (free)
Related: Opinion – “The EMR has changed the doctor-patient duet into a ménage-à-trois” (free resources on the subject)
Review: Management of Hypopituitarism
15 Jan, 2020 | 01:04h | UTCManagement of Hypopituitarism – Journal of Clinical Medicine (free)
Meta-Analysis: Benefits of Short-term or Prolonged as Compared to Standard 1 year DAPT in Patients with Acute Coronary Syndrome Treated with Drug-eluting Stents
14 Jan, 2020 | 00:44h | UTC
Review: Work Up of Fatty Liver by Primary Care Physicians
14 Jan, 2020 | 00:36h | UTCWork Up of Fatty Liver by Primary Care Physicians, Review – Annals of Medicine and Surgery (free)
Meta-Analysis of Cohort Studies: Important Food Sources of Fructose‐Containing Sugars and Incident Hypertension
14 Jan, 2020 | 00:31h | UTCCommentary: Does sugar raise blood pressure? It depends where it comes from, researchers say – University of Toronto (free)
[Abstract Only] Meta-Analysis: Opioids Not Beneficial for Chronic Osteoarthritis Pain
14 Jan, 2020 | 00:23h | UTCOpioids for chronic osteoarthritis pain. An updated systematic review and meta‐analysis of efficacy, tolerability and safety in randomized placebo‐controlled studies of at least four weeks double‐blind duration – European Journal of Pain (link to abstract – $ for full-text)
Related Systematic Review: Oral or transdermal opioids for osteoarthritis of the knee or hip – Cochrane Library (free)
[Abstract Only] Randomized Trial: Metoprolol and Aspirin Reduce Surrogate Measures of Cardiovascular Risk in Bereavement
14 Jan, 2020 | 00:14h | UTCThe effect of METOPROLOL and aspirin on cardiovascular risk in bereavement: A randomized controlled trial – American Heart Journal (link to abstract – $ for full-text)
[Abstract Only] Randomized Trial: Adding Acetaminophen to Ibuprofen Does Not Improve Symptoms in Acute Low Back Pain
14 Jan, 2020 | 00:12h | UTCIbuprofen Plus Acetaminophen Versus Ibuprofen Alone for Acute Low Back Pain: An Emergency Department–based Randomized Study – Academic Emergency Medicine (link to abstract – $ for full-text)
Commentary: RCT – Ibuprofen + Acetaminophen for Low Back Pain – JournalFeed (free)
Related: Paracetamol for low back pain – Cochrane Library (free)
Pregnancy-related Cardiovascular risk Indicators: Primary Care Approach to Postpartum Management and Prevention of Future Disease
14 Jan, 2020 | 00:07h | UTC
Special Issue: Practical Aspects of Palliative Care
12 Jan, 2020 | 21:25h | UTCHomepage: Palliative Care – Medicine (free articles)
– Palliative care: introduction
– Pain control in palliative care
– Interventional management of pain in cancer and palliative care
– Nausea and vomiting in palliative care
– Constipation and malignant bowel obstruction in palliative care
– Breathlessness in advanced disease
– Psychiatric conditions in palliative medicine
– Emergencies in palliative care
– Palliative care in non-malignant disease
– Management of less common symptoms in palliative care
– Complications of systemic anti-cancer treatment
– Care in the last hours and days of life
– Advance care-planning and clinical decision-making
– Ethical principles in end-of-life care
Study: Rifampicin is Likely to be the Safest Latent Tuberculosis Infection Treatment Option
12 Jan, 2020 | 21:26h | UTCAdverse events in adults with latent tuberculosis infection receiving daily rifampicin or isoniazid: post-hoc safety analysis of two randomised controlled trials – The Lancet Infectious Diseases (free registration required)
Commentaries: What is the best regimen to treat latent tuberculosis infection? – The Lancet Infectious Diseases (free) AND Four Months of Rifampicin May Be Best Option for Latent TB – Medscape / Reuters (free registration required)
Related Commentary on Twitter
New study @McGill_TB: “In patients without a contraindication, rifampicin is likely to be the safest latent tuberculosis infection treatment option.” https://t.co/rg2wmcLcqo
— Madhu Pai, MD, PhD (@paimadhu) January 9, 2020
Special Issue: Uncommon Severe Infections in the Intensive Care Unit
12 Jan, 2020 | 21:20h | UTCHomepage: Uncommon Severe Infections in the Intensive Care Unit – Clinical Microbiology and Infection (free articles)
– Improving care for the ICU patient with suspected infection: a multidisciplinary perspective
– Necrotizing skin and soft-tissue infections in the intensive care unit
– Management of infected pancreatic necrosis in the intensive care unit: a narrative review
– Mediastinitis in the intensive care unit patient: a narrative review
– When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit
Systematic Review and Economic Evaluation: Different Strategies for Pharmacological Thromboprophylaxis for Lower-limb Immobilization after Injury
12 Jan, 2020 | 21:14h | UTCSource: EvidenceAlerts
Observational Study: Implementation of a Hospital-Based Palliative Care Program Linked to Reduced Use of Intensive Care During Terminal Hospitalizations
12 Jan, 2020 | 20:55h | UTC
New Guideline on the Management of Epistaxis
10 Jan, 2020 | 08:30h | UTCClinical Practice Guideline: Nosebleed (Epistaxis) – Otolaryngology–Head and Neck Surgery (free)
Executive Summary: Clinical Practice Guideline: Nosebleed (Epistaxis) – Otolaryngology–Head and Neck Surgery (free)
News Release: Nosebleed (epistaxis): New clinical practice guideline – American Academy of Otolaryngology-Head and Neck Surgery (free)
Blood Pressure Measurement: A KDOQI Perspective
10 Jan, 2020 | 08:25h | UTCBlood Pressure Measurement: A KDOQI Perspective – American Journal of Kidney Diseases (free)
Cohort Study: Healthy Lifestyle Linked to Longer Life Expectancy Free of Major Chronic Diseases
10 Jan, 2020 | 08:17h | UTCCommentaries: Healthy habits add up to 10 disease-free years to your life, study reveals – NHS Choices (free) AND 5 healthful living factors extend disease-free life – Medical News Today (free) AND Healthy habits ‘deliver extra disease-free decade’ – BBC (free)
Cryptogenic Stroke: Diagnostic Workup and Management
9 Jan, 2020 | 23:37h | UTC
Study Commentary: Taking Blood Pressure Medications at Night Seems Best
9 Jan, 2020 | 23:24h | UTCTaking blood pressure medications at night seems best – NIHR Signal (free)
Original Study: Practice Changing? – Bedtime Hypertension Treatment Improves Cardiovascular Risk Reduction in Randomized Trial – European Heart Journal (free study and commentaries)
Study Commentary: ‘As-needed’ Combination Asthma Inhalers Can be More Effective than Regular Inhaled Steroids
9 Jan, 2020 | 23:12h | UTCOriginal Study: Randomized Trial: In Adults with Mild to Moderate Asthma, As-Needed Long-acting Beta-agonist Plus an Inhaled Corticosteroid is as Effective as Maintenance Inhaled Corticosteroid Therapy Plus As-needed Short-acting Beta-agonist – The Lancet (link to abstract and commentary)
5 Practices to Foster Physician Presence and Connection with Patients in the Clinical Encounter
9 Jan, 2020 | 01:26h | UTCPractices to Foster Physician Presence and Connection With Patients in the Clinical Encounter – JAMA (free for a limited period)
Editorials: Can an Evidence-Based Approach Improve the Patient-Physician Relationship? (free for a limited period) AND Connecting With Patients—The Missing Links (free for a limited period)
Author Interview: Practices to Foster Physician Presence and Connection with Patients in the Clinical Encounter (free)
Video: Connecting With Patients in Medicine (free)