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Internal Medicine

8 Things to Know About E-cigarettes

6 Mar, 2020 | 10:25h | UTC

8 things to know about e-cigarettes – Public Health Matters (free)

Related Report: Vaping in England: evidence update March 2020 – Public Health England (free)

 


FDA Safety Alert: Montelukast May Cause Serious Mental Health Side Effects

6 Mar, 2020 | 10:22h | UTC

FDA requires Boxed Warning about serious mental health side effects for asthma and allergy drug montelukast (Singulair); advises restricting use for allergic rhinitis – U.S. Food & Drug Administration (free)

Commentary: Montelukast to Get Boxed Warning – NEJM Journal Watch (free)

 


Randomized Trial: Effect of a Workplace-Based Multicomponent Intervention on Hypertension Control

6 Mar, 2020 | 10:21h | UTC

Effect of a Workplace-Based Multicomponent Intervention on Hypertension Control: A Randomized Clinical Trial – JAMA Cardiology (free for a limited period)

Commentary: Blood pressure control achieved using workplace-based programs – News Medical (free)

 


Blood Pressure in Frail Older Adults: Associations with Cardiovascular Outcomes and All-cause Mortality

6 Mar, 2020 | 10:19h | UTC

Blood pressure in frail older adults: associations with cardiovascular outcomes and all-cause mortality – Age and Ageing (free)

Commentary: Expert reaction to study looking at low blood pressure and mortality in older adults – Science Media Centre (free)

 

Related Commentary on Twitter

 


Study: New 3-Drug Treatment Regimen Effective for Highly Drug-Resistant Pulmonary Tuberculosis

5 Mar, 2020 | 10:30h | UTC

Treatment of Highly Drug-Resistant Pulmonary Tuberculosis – New England Journal of Medicine (free)

Visual Abstract: Treatment of Highly Drug-Resistant Pulmonary TB (free)

Commentary: New TB drug regimen controls resistant disease in 9 of 10 cases: study – Reuters (free)

 


Cohort Study: Comparing the 5-Year Diabetes Outcomes of Sleeve Gastrectomy and Gastric Bypass

5 Mar, 2020 | 10:24h | UTC

Comparing the 5-Year Diabetes Outcomes of Sleeve Gastrectomy and Gastric Bypass: The National Patient-Centered Clinical Research Network (PCORNet) Bariatric Study – JAMA Surgery (free)

Commentaries: Bariatric Surgery and Diabetes Treatment—Finding the Sweet Spot – JAMA Surgery (free) AND Gastric bypass may be best weight-loss surgery for diabetes remission – Reuters (free) AND Gastric bypass improves weight loss, type 2 diabetes, study finds – UPI (free)

 


Meta-Analysis: Watchful Waiting Strategy vs. Early Initiation of Renal Replacement Therapy in Critically Ill Patients with Acute Kidney Injury

5 Mar, 2020 | 10:25h | UTC

Comparison between watchful waiting strategy and early initiation of renal replacement therapy in the critically ill acute kidney injury population: an updated systematic review and meta-analysis – Annals of Intensive Care (free)

Related: Review: Renal Replacement Therapy in the Critical Care Setting (free resources)

 


Another Egg Study. Three Large Prospective Cohort Studies, Systematic Review, and Updated Meta-analysis Suggest It Has a Neutral Effect on Risk of Cardiovascular Disease

5 Mar, 2020 | 10:19h | UTC

Egg consumption and risk of cardiovascular disease: three large prospective US cohort studies, systematic review, and updated meta-analysis – The BMJ (free)

Editorial: Egg consumption and cardiovascular disease (free)

Commentary: Study Finds No Link Between Moderate Egg Consumption and Overall Cvd Risk – MedicalResearch.com (free)

 


Short Review: Time‐Sensitive Interventions in Hospitalized Patients with Cirrhosis

4 Mar, 2020 | 08:24h | UTC

Time‐Sensitive Interventions in Hospitalized Patients with Cirrhosis – Clinical Liver Disease (free)

 


[Abstract Only] Observational Study Suggests Flu Vaccine May Not Decrease Hospitalization or Mortality Among Elderly Persons

4 Mar, 2020 | 08:27h | UTC

The Effect of Influenza Vaccination for the Elderly on Hospitalization and Mortality: An Observational Study With a Regression Discontinuity Design – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Flu vaccine may not decrease hospitalization or mortality among elderly persons – American College of Physicians (free) AND Expert reaction to study looking at the flu vaccine and hospitalisation and mortality in older people – Science Media Centre (free) AND Isolated flu vaccination of elderly may not decrease hospitalization or mortality rates – ACP Internist (free)

 


Cohort Study: Vegetarian Diet Linked to Lower Incidence of Total, Ischemic, and Hemorrhagic Stroke

4 Mar, 2020 | 08:12h | UTC

Vegetarian diet and incidence of total, ischemic, and hemorrhagic stroke in 2 cohorts in Taiwan – Neurology (free)

Commentary: Eating a vegetarian diet rich in nuts, vegetables, soy linked to lower stroke risk – American Academy of Neurology (free)

 


USPSTF Statement: Screening for Hepatitis C Virus Infection in Adolescents and Adults

3 Mar, 2020 | 08:03h | UTC

Recommendation Statement: Screening for Hepatitis C Virus Infection in Adolescents and Adults: US Preventive Services Task Force (free)

Author Interview: USPSTF Recommendation: Screening for Hepatitis C Virus Infection in Adolescents and Adults (free audio)

Editorials: Universal Screening for Hepatitis C Virus Infection: A Step Toward Elimination – JAMA (free for a limited period) AND USPSTF’s Hepatitis C Screening Recommendation—A Necessary Step to Tackling an Evolving Epidemic – JAMA Network Open (free)

Evidence Report and Systematic Review: Screening for Hepatitis C Virus Infection in Adolescents and Adults – US Preventive Services Task Force (free)

JAMA Patient Page: Screening for Hepatitis C Virus Infection (free)

Commentary: Experts recommend testing U.S. adults ages 18-79 for hep C – Reuters (free)

 


Catheter-Associated Urinary Tract Infections in Adult Patients: Preventive Strategies and Treatment Options

3 Mar, 2020 | 07:44h | UTC

Catheter- Associated Urinary Tract Infections in Adult Patients: Preventive strategies and treatment options – Deutsches Ärzteblatt international (free)

 


Study: People Leave Hospital After Surgery Sooner if Hospitals Follow ‘Enhanced Recovery Protocols’

3 Mar, 2020 | 07:55h | UTC

People leave hospital after surgery sooner if hospitals follow ‘enhanced recovery protocols’ – NIHR Signal (free)

Original Study: Multicomponent hospital-led interventions to reduce hospital stay for older adults following elective surgery: a systematic review – Health Services and Delivery Research (free)

 


State of the Art Review: Current and Future Treatments for Tuberculosis

3 Mar, 2020 | 07:59h | UTC

Current and future treatments for tuberculosis – The BMJ (free for a limited period)

 

Related Commentary on Twitter

 


Systematic Review: Computerized Cognitive Training May Have Small Benefits of Uncertain Clinical Importance for Maintaining Cognitive Function in Cognitively Healthy People in Late Life

3 Mar, 2020 | 07:46h | UTC

Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively healthy people in late life – Cochrane Library (free)

Summary: Computerised cognitive training for maintaining cognitive function in cognitively healthy people in late life – Cochrane Library (free)

 


Podcast: Pulmonary Nodules and Lung Cancer Screening

3 Mar, 2020 | 07:34h | UTC

#197 Pulmonary Nodules and Lung Cancer Screening with Denitza Blagev MD – The Curbsiders Internal Medicine Podcast (free)

 


COVID-19—New Insights on a Rapidly Changing Epidemic

1 Mar, 2020 | 19:45h | UTC

COVID-19—New Insights on a Rapidly Changing Epidemic – JAMA (free)

See also: Latest Developments in the COVID-19 Outbreak (several resources on the subject)

 


Meta-Analysis: Efficacy of Antidepressants are of Questionable Importance to the Average Patient

1 Mar, 2020 | 19:39h | UTC

Efficacy of new-generation antidepressants assessed with the Montgomery-Asberg Depression Rating Scale, the gold standard clinician rating scale: A meta-analysis of randomised placebo-controlled trials – PLOS One (free)

Related: Evidence Synthesis: Should Antidepressants be Used for Major Depressive Disorder? (free studies on the subject)

 


Study: Clinical Characteristics of Coronavirus Disease 2019 in China

1 Mar, 2020 | 19:50h | UTC

Clinical Characteristics of Coronavirus Disease 2019 in China – New England Journal of Medicine (free)

Editorial: Covid-19 — Navigating the Uncharted – New England Journal of Medicine (free)

Related Commentaries: Responding to Covid-19 — A Once-in-a-Century Pandemic? – New England Journal of Medicine (free) AND Escaping Pandora’s Box — Another Novel Coronavirus – New England Journal of Medicine (free)

See also: Latest Developments in the COVID-19 Outbreak (several resources on the subject)

 


Alex Nowbar’s journal reviews—28 February 2020

1 Mar, 2020 | 19:38h | UTC

Alex Nowbar’s journal reviews, 28 February 2020 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

Related Commentary on Twitter

 


Infographic. Exercise for Intermittent Claudication

1 Mar, 2020 | 19:30h | UTC

Infographic. Exercise for intermittent claudication – British Journal of Sports Medicine (free)

Commentary: Walking may be best treatment for pain from clogged leg arteries – Reuters (free)

 


Essentials for Radiologists on COVID-19: An Update—Radiology Scientific Expert Panel

1 Mar, 2020 | 19:26h | UTC

Essentials for Radiologists on COVID-19: An Update—Radiology Scientific Expert Panel – Radiology (free)

Related: COVID-19: Chest CT May be the Best Screening Tool for Diagnosis in Epidemic Areas (free studies on the subject) AND Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study – The Lancet Infectious Diseases (free) AND Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2 – European Journal of Nuclear Medicine and Molecular Imaging (free PDF) AND Chest CT Findings in Patients with Corona Virus Disease 2019 and its Relationship with Clinical Features – Investigative Radiology (free PDF) AND 2019 Novel Coronavirus (COVID-19) Pneumonia: Serial Computed Tomography Findings – Korean Journal of Radiology (free PDF) AND Chest Radiographic and CT Findings of the 2019 Novel Coronavirus Disease (COVID-19): Analysis of Nine Patients Treated in Korea – Korean Journal of Radiology (free PDF)

See also: Latest Developments and Research in the COVID-19 Outbreak (several resources on the subject)

 


Meta-Analysis: Effect of Reduction in Dietary Sodium on Blood Pressure Levels

28 Feb, 2020 | 08:35h | UTC

Effect of dose and duration of reduction in dietary sodium on blood pressure levels: systematic review and meta-analysis of randomised trials – The BMJ (free)

Commentaries: Further evidence adds weight to call for urgent action on salt targets – George Institute for Global Health (free) AND Cutting salt likely to prevent future heart disease, even if you’re not at risk now – CNN (free)

 

Related Commentary on Twitter

 


NICE Guideline: Antimicrobial Prescribing Guidance for Impetigo

27 Feb, 2020 | 08:45h | UTC

Impetigo: antimicrobial prescribing – National Institute for Health and Care Excellence (free)

Commentary: Antiseptic not antibiotic should be considered for impetigo – PharmaField (free)

Related: NICE Antimicrobial prescribing guidelines (resource covering many common conditions) AND NICE Summary of antimicrobial prescribing guidance – managing common infections (free PDF)

 


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