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Internal Medicine

Management of Acute Kidney Injury in Patients with COVID-19

19 May, 2020 | 04:40h | UTC

Management of acute kidney injury in patients with COVID-19 – The Lancet Respiratory Medicine

Related: Acute Kidney Injury In Patients Hospitalized With Covid-19 – Kidney International

 

Cross-neutralization of SARS-CoV-2 by a Human Monoclonal SARS-CoV Antibody

19 May, 2020 | 04:35h | UTC

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody – Nature

Commentary: Cross-neutralization of SARS and COVID-19 coronaviruses by a monoclonal antibody – News Medical

 

Early Data Show Moderna Covid-19 Vaccine Generates Immune Response

19 May, 2020 | 04:29h | UTC

Early data show Moderna Covid-19 vaccine generates immune response – STAT

See also: Moderna Coronavirus Vaccine Trial Shows Promising Early Results – The New York Times AND Expert reaction to Moderna announcement about their phase 1 trial data on their mRNA vaccine (mRNA-1273) candidate against COVID-19 – Science Media Centre

 

New NICE Covid-19 Rapid Guidelines: Chronic Kidney Disease & Interstitial Lung Disease

18 May, 2020 | 02:15h | UTC

COVID-19 rapid guideline: chronic kidney disease – National Institute for Health and Care Excellence

COVID-19 rapid guideline: interstitial lung disease – National Institute for Health and Care Excellence

See also: Complete Collection of Covid-19 Rapid Guidelines

 

Randomized Trial: No Benefit from Hydroxychloroquine in Patients with Mild to Moderate Covid-19

18 May, 2020 | 02:11h | UTC

Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial – The BMJ

Commentary: Further evidence does not support hydroxychloroquine for patients with COVID-19 – BMJ

 

Clinical Practice: Severe Covid-19

18 May, 2020 | 02:09h | UTC

Severe Covid-19 – New England Journal of Medicine

 

Hemostasis Disorders in Critically Ill Patients with COVID-19

18 May, 2020 | 02:08h | UTC

Understanding pathophysiology of hemostasis disorders in critically ill patients with COVID-19 – Intensive Care Medicine

 

Related Commentary on Twitter

 

LDH, Lymphocyte Count, and C-reactive protein can Predict Mortality in Covid-19

18 May, 2020 | 01:58h | UTC

An interpretable mortality prediction model for COVID-19 patients – Nature Machine Learning

 

Related Commentary on Twitter

 

Clinical and Chest Radiography Features Determine Patient Outcomes In COVID-19

18 May, 2020 | 01:59h | UTC

Clinical and Chest Radiography Features Determine Patient Outcomes In Young and Middle Age Adults with COVID-19 – Radiology

 

Risk Factors for SARS-CoV-2 in Patients with Symptoms

18 May, 2020 | 01:55h | UTC

Assessing risk factors for SARS-CoV-2 infection in patients presenting with symptoms in Shanghai, China: a multicentre, observational cohort study – Lancet Digital Health

 

Risk factors for SARS-CoV-2 in a Primary Care Network

18 May, 2020 | 01:56h | UTC

Risk factors for SARS-CoV-2 among patients in the Oxford Royal College of General Practitioners Research and Surveillance Centre primary care network: a cross-sectional study – The Lancet Infectious Diseases

Commentaries: Who is most likely to be infected with SARS-CoV-2? – The Lancet Infectious Diseases AND Sociodemographic factors associated with a positive test for COVID-19 in primary care – The Lancet AND COVID-19 discriminates along racial, socioeconomic lines, study finds – UPI

 

Systematic Review: Risks and Impact of ACE Inhibitors or ARBs on SARS-CoV-2 Infection in Adults

18 May, 2020 | 01:47h | UTC

Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults: A Living Systematic Review – Annals of Internal Medicine

Editorial: COVID-19 and Angiotensin-Converting Enzyme Inhibitor/Angiotensin-Receptor Blocker Therapy – Annals of Internal Medicine

 

Randomized Trial: Graduated Compression Stockings in Elective Surgical Patients

18 May, 2020 | 01:41h | UTC

Graduated compression stockings as adjuvant to pharmaco-thromboprophylaxis in elective surgical patients (GAPS study): randomised controlled trial – The BMJ

Commentaries: Graduated compression stockings on trial – The BMJ Opinion AND Compression stockings might not be needed to prevent blood clots after surgery – The British Medical Journal

 

Study: Use of Renin–angiotensin–aldosterone System Inhibitors Does Not Increase the Risk of COVID-19 Requiring Admission to Hospital

18 May, 2020 | 01:45h | UTC

Use of renin–angiotensin–aldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case-population study – The Lancet

Commentary: Hypertension, renin–angiotensin–aldosterone system inhibition, and COVID-19 – The Lancet

 

[Preprint] Early Safety Indicators of COVID-19 Convalescent Plasma in 5,000 Patients

15 May, 2020 | 03:50h | UTC

Early Safety Indicators of COVID-19 Convalescent Plasma in 5,000 Patients – medRxiv

Commentary: Convalescent plasma is safe to treat COVID-19: nationwide study – NBC News

 

Systematic Review: Plasma from People who Have Recovered from COVID-19 to Treat Individuals with COVID-19

15 May, 2020 | 03:48h | UTC

Convalescent plasma or hyperimmune immunoglobulin for people with COVID‐19: a rapid review – Cochrane Library

Summary: Plasma from people who have recovered from COVID-19 to treat individuals with COVID-19 – Cochrane Library

 

Study: Airborne Lifetime of Small Speech Droplets and their Potential Importance in SARS-CoV-2 Transmission

15 May, 2020 | 03:43h | UTC

The airborne lifetime of small speech droplets and their potential importance in SARS-CoV-2 transmission – Proceedings of the National Academy of Sciences

Commentaries: Expert reaction to study looking at speech-generated droplets and COVID-19 transmission – Science Media Centre AND Loud Talking Can Spread More than 1,000 Coronavirus Particles in the Air for 14 Minutes: Study – The Science Times AND Simply talking in confined spaces may be enough to spread the coronavirus, researchers say – USA Today AND Loud talking could leave coronavirus in the air for up to 14 minutes – MIT Technology Review

 

ACP Systematic Review: Chloroquine or Hydroxychloroquine Alone or in Combination with Azithromycin for the Prophylaxis or Treatment of COVID-19

15 May, 2020 | 03:32h | UTC

Should Clinicians Use Chloroquine or Hydroxychloroquine Alone or in Combination With Azithromycin for the Prophylaxis or Treatment of COVID-19? – Annals of Internal Medicine

 

Study Commentary: Before/after Study of Short-Course Steroid in COVID-19

14 May, 2020 | 10:09h | UTC

Before/after study of short-course steroid in COVID-19 – PulmCrit

Original Study (Preprint): Early Short Course Corticosteroids in Hospitalized Patients with COVID-19 – medRxiv

 

Meta-Analysis: Manifestations and Prognosis of Gastrointestinal and Liver Involvement in COVID-19

14 May, 2020 | 10:16h | UTC

Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis – The Lancet Gastroenterology & Hepatology

Related: Gastrointestinal, Hepatobiliary, and Pancreatic Manifestations of COVID-19 (review and guideline) AND Abdominal Imaging Findings in COVID-19: Preliminary Observations – Radiology

 

New Study Does Not Support the Idea that BCG Vaccination Protects Against COVID-19

14 May, 2020 | 10:12h | UTC

SARS-CoV-2 Rates in BCG-Vaccinated and Unvaccinated Young Adults – JAMA

Related: BCG Against Coronavirus: Less Hype And More Evidence, Please – Forbes AND Does BCG vaccination protect against acute respiratory infections and COVID-19? A rapid review of current evidence – CEBM University of Oxford AND Bacille Calmette-Guérin (BCG) vaccination and COVID-19 – World Health Organization

 

ERS Guideline: Withdrawal of Inhaled Corticosteroids in COPD

14 May, 2020 | 02:17h | UTC

Withdrawal of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease: A European Respiratory Society Guideline – European Respiratory Journal

 

Research Round-up: COPD

14 May, 2020 | 02:20h | UTC

Research round-up: COPD – Nature

Related: Should physicians still be prescribing steroid inhalers as a first-line treatment for COPD? – Nature AND Redefining the diagnostic criteria for COPD – Nature

See other articles from the series:  Nature Outlook on COPD

 

Cohort Study: Pulmonary Rehabilitation Linked to Improved Survival After Hospitalization for COPD

14 May, 2020 | 02:14h | UTC

Association Between Initiation of Pulmonary Rehabilitation After Hospitalization for COPD and 1-Year Survival Among Medicare Beneficiaries – JAMA (free for a limited period)

Editorial: Pulmonary Rehabilitation and Improved Survival for Patients With COPD (free for a limited period)

 

Meta-Analysis: Progression to Type 2 Diabetes in Women with Previous Gestational Diabetes

14 May, 2020 | 02:11h | UTC

Progression to type 2 diabetes in women with a known history of gestational diabetes: systematic review and meta-analysis – The BMJ

Commentary: Gestational diabetes—missed opportunities in post-partum follow-up – The BMJ Opinion

 

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