Internal Medicine
In patients hospitalized with COVID-19, right ventricular dilation or dysfunction was independently associated with a >2-fold increase in risk for mortality
10 Nov, 2020 | 09:36h | UTCCommentaries: Utility of RV Remodeling Over Risk Stratification in COVID-19 – American College of Cardiology AND Damage to heart’s right ventricle predicts a greater chance of death from COVID-19 – Weill Cornell Medical College
Aspirin to be investigated as a possible treatment for COVID-19 in the RECOVERY trial
10 Nov, 2020 | 09:35h | UTCCommentary: Aspirin to be tested as potential COVID-19 drug in UK study – Reuters
Cohort study: Nighttime high blood pressure phenotype linked to worse cardiovascular prognosis
10 Nov, 2020 | 09:29h | UTCCommentaries: People who experience high blood pressure while sleeping have increased risk of heart attacks, strokes – News Medical / American Heart Association AND Sleeptime BP Spikes Tied to Heart Troubles – Physician’s Weekly
Perioperative evaluation and management of patients with diabetes, thyroid disease, and adrenal insufficiency. Use of insulin and noninsulin diabetic medications, management of hyper and hypothyroidism, and use of stress-dose corticosteroids are some of the subjects reviewed
10 Nov, 2020 | 09:24h | UTCPerioperative Evaluation and Management of Endocrine Disorders – Mayo Clinic Proceedings
What can we expect from new SARS-CoV-2 rapid tests? They promise to aid public health responses to COVID-19, since they can deliver results in a matter of minutes in the field, rather than taking days in clinical diagnostic labs
9 Nov, 2020 | 01:30h | UTCCoronavirus testing finally gathers speed – Nature
[Not published yet – presented at #ACR20] Randomized trial: Methotrexate improves function in people with knee osteoarthritis after 3 months
9 Nov, 2020 | 01:19h | UTC
Guideline synopsis for follow-up colonoscopy after polypectomy. Repeat Col in 7 to 10 y after 1 to 2 tubular adenomas (TA) < 10 mm; Repeat Col in 3 to 5 y after 3 to 4 TA < 10 mm; Repeat Col in 3 y after 5 to 10 TA < 10 mm; Repeat Col in 3 years after 1 or more TA > 10 mm
9 Nov, 2020 | 01:17h | UTCRecommendations for Follow-up Colonoscopy After Polypectomy – JAMA (free for a limited period)
Author interview: New Recommendations for How Often to Repeat Colonoscopy Following Polypectomy
Original guideline: Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastroenterology
Another study shows improved outcomes with dual antiplatelet therapy in the first weeks after an acute ischemic stroke or transient ischemic attack
9 Nov, 2020 | 01:16h | UTCRelated Guideline: Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke – The BMJ
[Abstract Only] Large randomized trial fails to show benefit from a multifactorial prevention strategy to prevent falls and fractures in older people
6 Nov, 2020 | 09:48h | UTCScreening and Intervention to Prevent Falls and Fractures in Older People – New England Journal of Medicine (link to abstract – $ for full-text)
Related study: A Randomized Trial of a Multifactorial Strategy to Prevent Serious Fall Injuries – New England Journal of Medicine
[Abstract Only] More than a third of older adults are prescribed potentially inappropriate drugs, study finds
6 Nov, 2020 | 09:42h | UTCOriginal study: Potentially Inappropriate Medications Are Associated with Increased Healthcare Utilization and Costs – Journal of the American Geriatrics Society (link to abstract – $ for full-text)
JACC Review: Evaluation and management of patients with stable angina. Based on large clinical trials, medical therapy rather than revascularization is the initial management strategy for most patients
6 Nov, 2020 | 09:43h | UTCEvaluation and Management of Patients With Stable Angina: Beyond the Ischemia Paradigm: JACC State-of-the-Art Review – Journal of the American College of Cardiology (free for a limited period)
Summary: Evaluation and Management of Patients With Stable Angina – American College of Cardiology
[Abstract Only] Randomized trial: In patients with anorexia nervosa, a higher-calorie refeeding approach promotes earlier recovery with no increase in safety events during hospitalization
6 Nov, 2020 | 09:31h | UTCShort-term Outcomes of the Study of Refeeding to Optimize Inpatient Gains for Patients With Anorexia Nervosa: A Multicenter Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text0
Commentaries: Higher calorie treatment for people hospitalized with anorexia – NIH News Releases AND Higher-calorie diets for patients with anorexia nervosa shorten hospital stays – University of California – San Francisco
Commentary on Twitter
Great paper by @AndreaGarber2 showing that higher-calorie refeeding in #anorexia nervosa does not come at a higher risk of refeeding syndrome and can shorten hospital stays which is advantageous for both the patients/families and the medical system.https://t.co/aFQZKycpTX
— Jonas Steinhäuser (@JoSte95) October 30, 2020
Hot off the presses! Largest clinical trial of refeeding in #anorexianervosa shows that a higher-calorie approach is more efficacious & less costly than lower-calorie refeeding, with no increase in safety events & significant savings in healthcare costs. https://t.co/F0ciJAORdq
— UCSF EatingDisorders (@UCSF_EDP) October 20, 2020
High prevalence of pericardial involvement in college student-athletes recovering from COVID-19
5 Nov, 2020 | 09:08h | UTC
Commentary on Twitter
The heart and #COVID19 in 54 consecutive college athletes @WVUHealth w/ echo, MRIhttps://t.co/76DvMNaeBL @JACCJournals todayhttps://t.co/hMyY8cQNln @ppsengupta1 @BritoCardio
>1/3 had resolving pericarditis with mild-moderate covid or no symptoms; no myocarditis, no controls pic.twitter.com/GTj3JZxL26— Eric Topol (@EricTopol) November 5, 2020
Postmortem lungs of COVID-19 patients show massive damage
5 Nov, 2020 | 09:06h | UTCPostmortem lungs of COVID-19 patients show massive damage- CIDRAP
Original article: Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology – EBioMedicine
NICE Guideline: Human and animal bites. Assessment, indications for antibiotic prophylaxis in uninfected bites, and choice of antibiotic are reviewed
5 Nov, 2020 | 09:02h | UTC
Review: Electrodiagnostic studies can help establish if a patient is likely to have a muscle disease, a disorder of neuromuscular junction transmission, axon loss, or demyelinating disease
5 Nov, 2020 | 08:56h | UTCUsing and interpreting electrodiagnostic tests – Cleveland Clinic Journal of Medicine
Review: Clinical Management of Hyperkalemia. Classification and monitoring, when to reinitiate RAASi therapy, use oral K+-binding agents, and more
5 Nov, 2020 | 08:58h | UTCClinical Management of Hyperkalemia – Mayo Clinic Proceedings
Review: Diagnosis and treatment of lower extremity venous thromboembolism. Role of pretest probability and D-Dimer on diagnosis + treatment issues such as postthrombotic syndrome and the role of new anticoagulants
5 Nov, 2020 | 09:00h | UTCDiagnosis and Treatment of Lower Extremity Venous Thromboembolism: A Review – JAMA (free for a limited period)
Summary: Diagnosis and Treatment of Lower Extremity Venous Thromboembolism – American College of Cardiology
Screening: earlier detection of disease is not necessarily better
5 Nov, 2020 | 08:53h | UTCScreening: earlier detection of disease is not necessarily better – Evidently Cochrane
Systematic Review: Little benefit from phlebotonics in patients with venous insufficiency
5 Nov, 2020 | 08:54h | UTCPhlebotonics for venous insufficiency – Cochrane Library
SARS-CoV-2 seroprevalence and transmission risk factors among high-risk close contacts
4 Nov, 2020 | 09:51h | UTC
Commentary on Twitter
Important new study on #SARSCoV2 transmission of >1,100 cases with 7,700 close contacts
— 36% asymptomatic; require testing
— Household contact risk: sharing bedroom >5X; speaking w/ 1° case for ≥ 30 min: 7.9Xhttps://t.co/lSKebOzoNf @TheLancetInfDis pic.twitter.com/UTtkCUqlRn— Eric Topol (@EricTopol) November 3, 2020
New CDC Report found that pregnant women with Covid-19 are more likely to have severe illness
4 Nov, 2020 | 09:47h | UTCCommentary: Pregnant women with Covid-19 face higher risk of severe illness and death, study says – CNN
Randomized trial: Vitamin C does not improve iron absorption in adult patients with iron deficiency anemia
4 Nov, 2020 | 09:42h | UTCCommentary: Study: Vitamin C Supplements Have No Effect on Iron-Deficiency Anemia – NEJM Journal Watch
Commentary on Twitter
RCT finds oral iron alone is equivalent to oral iron + #vitaminC in improving hemoglobin and iron absorption in patients with iron deficiency #anemia https://t.co/atSVVnGkEV #VisualAbstract
— JAMA Network Open (@JAMANetworkOpen) November 2, 2020
Low carbohydrate diet: Insights from a general practice service in patients with type 2 diabetes
4 Nov, 2020 | 09:38h | UTC
Commentary on Twitter
PUBLISHED! We wanted to showcase what a low-carb approach could achieve for people with #T2D in UK NHS general practice Our @BMJNutrition paper published today. Open access PLEASE read it https://t.co/zxj2XESBaO HUGE thanks to patients and staff @nnedpro Hurrah! pic.twitter.com/BLML1vSA6i
— Dr David Unwin (@lowcarbGP) November 3, 2020
Review: Management of common postoperative complications
4 Nov, 2020 | 09:26h | UTCManagement of Common Postoperative Complications – Mayo Clinic Proceedings