Internal Medicine
CDC Guidelines for Gonococcal Infection, 2020. CDC recommends a single 500 mg intramuscular dose of ceftriaxone for uncomplicated gonorrhea, with oral doxycycline for 7 days when chlamydial coinfection has not been excluded
18 Dec, 2020 | 09:40h | UTCCommentary: CDC Guidelines Recommend Ceftriaxone Monotherapy for Uncomplicated Gonorrhea – NEJM Journal Watch
Commentary on Twitter
https://twitter.com/GarrettHile/status/1339732944613720064
Meta-analysis: Lung cancer screening using low-dose computed tomography reduces lung cancer–specific mortality, albeit with a tradeoff of likely overdiagnosis
16 Dec, 2020 | 10:08h | UTC
ACG Clinical Guideline: Management of irritable bowel syndrome
16 Dec, 2020 | 10:09h | UTC
Randomized trial: Dexamethasone for chronic subdural hematoma resulted in fewer favorable outcomes and more adverse events than placebo at 6 months
17 Dec, 2020 | 09:02h | UTCTrial of Dexamethasone for Chronic Subdural Hematoma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Dexamethasone should be avoided in patients with chronic subdural haematoma – University of Cambridge AND Dexamethasone for Chronic Subdural Hematoma? – NEJM Journal Watch
Commentary on Twitter
In a trial that compared a 2-week course of dexamethasone with placebo in patients with a chronic subdural hematoma, a favorable outcome on the modified Rankin scale at 6 months was more common in the placebo group than in the dexamethasone group.
— NEJM (@NEJM) December 17, 2020
Guideline: ADA 2021 Standards of Medical Care in Diabetes
10 Dec, 2020 | 00:11h | UTCJust published! New ADA 2022 Guideline for the Management of Diabetes
Guideline Homepage: ADA 2021 Standards of Medical Care in Diabetes – American Diabetes Association (free supplement)
See ADA 2021 Guideline topics below:
Introduction: Standards of Medical Care in Diabetes—2021
Summary of Revisions: Standards of Medical Care in Diabetes—2021
- Improving Care and Promoting Health in Populations: Standards of Medical Care in Diabetes—2021
- Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2021
- Prevention or Delay of Type 2 Diabetes: Standards of Medical Care in Diabetes—2021
- Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Medical Care in Diabetes—2021
- Facilitating Behavior Change and Well-being to Improve Health Outcomes: Standards of Medical Care in Diabetes—2021
- Glycemic Targets: Standards of Medical Care in Diabetes—2021
- Diabetes Technology: Standards of Medical Care in Diabetes—2021
- Obesity Management for the Treatment of Type 2 Diabetes: Standards of Medical Care in Diabetes—2021
- Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes—2021
- Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes—2021
- Microvascular Complications and Foot Care: Standards of Medical Care in Diabetes—2021
- Older Adults: Standards of Medical Care in Diabetes—2021
- Children and Adolescents: Standards of Medical Care in Diabetes—2021
- Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes—2021
- Diabetes Care in the Hospital: Standards of Medical Care in Diabetes—2021
- Diabetes Advocacy: Standards of Medical Care in Diabetes—2021
Commentary on Twitter
ADA's "Standards of Medical Care in Diabetes—2021" is finally here! Featuring American Diabetes Association's latest clinical practice recommendations, the global standard for diabetes care. #ADASOC2021
📖 READ NOW (OPEN ACCESS): https://t.co/VyIT2yJnW8 pic.twitter.com/vOM5XXKLoU
— ADA Professional Publications (@ADA_Pubs) December 9, 2020
Survey study: Sleep-related impairment among doctors linked to increased clinically significant medical errors
17 Dec, 2020 | 08:53h | UTCCommentaries: Lack of sleep tied to physician burnout, medical errors – MedicalXpress AND Poor Physician Sleep Associated with More Medical Errors – NEJM Journal Watch
Commentary on Twitter
Survey study: sleep-related impairment associated with higher burnout & lower professional fulfillment, as well as independent dose-response association with self-reported physician medical errors. @StanfordMed https://t.co/FPk4tYnDT1
— JAMA Network Open (@JAMANetworkOpen) December 9, 2020
Randomized trial: In surgical patients at moderate or high risk of venous thromboembolism, pharmaco-thromboprophylaxis alone is as good as the combination of pharmaco-thromboprophylaxis and graduated compression stockings
16 Dec, 2020 | 10:00h | UTC
COVID-19 is 10 times deadlier for people with Down syndrome, raising calls for early vaccination
17 Dec, 2020 | 08:51h | UTC
Study: Filtration efficiency of face masks used by the public during the COVID-19 pandemic are, in many cases, nearly equivalent to or better than their non-N95 respirator medical mask counterparts
17 Dec, 2020 | 08:43h | UTCEditorial: Filtration Efficiency of Face Masks Used by the Public During the COVID-19 Pandemic
Commentary on Twitter
Marked reassurance on the value of cloth masks.
A new @JAMAInternalMed assessment today https://t.co/bTrurKeG71 Attention to fit is key, such as aluminum nose bridge, ties, no beard, etc 😷😷 @Phillip_Clapp @UNC_SOM pic.twitter.com/ZCMTT2OWXc— Eric Topol (@EricTopol) December 11, 2020
Individual and community-level risk predictor for COVID-19 mortality in the US, with risk calculator
16 Dec, 2020 | 09:42h | UTCIndividual and community-level risk for COVID-19 mortality in the United States – Nature Medicine
Calculator: Covid-19 risk
Commentary on Twitter
New @NatureMedicine
What is your individualized risk of dying from covid19?https://t.co/Bg61t3raVNhttps://t.co/tQGH0ilsmR (1.1X for me) pic.twitter.com/9pkwyCUAVw— Eric Topol (@EricTopol) December 11, 2020
COVID-19 mimics on chest CT: a pictorial review and radiologic guide
17 Dec, 2020 | 08:37h | UTC
Video (5min): Ivermectin for COVID-19 | A Doctor Explains
16 Dec, 2020 | 09:43h | UTCIvermectin For COVID-19 | A Doctor Explains – ZDoggMD
Longer time spent at home during COVID-19 pandemic is associated with binge drinking among US adults
16 Dec, 2020 | 09:36h | UTCCommentaries: New study shows every week of lockdown increases binge drinking – MedicalXpress AND Study finds more binge drinking during stay-at-home lockdowns – MedicalXpress
Report: Lung transplantation for 3 patients with severe COVID-19
16 Dec, 2020 | 09:34h | UTCLung transplantation for patients with severe COVID-19 – Science Translational Medicine
Commentaries: COVID-19 can damage lungs so badly that ‘only hope’ is transplant – MedicalXpress
Commentary on Twitter
Case reports from 3 patients with severe #COVID19 who received lung transplants show the disease can cause extensive lung damage similar to that seen in pulmonary #fibrosis, and hints transplantation may be a viable treatment. @NUFeinbergMed @ScienceTM https://t.co/wXi0tx8gFg pic.twitter.com/vyerJLlJxi
— Science Magazine (@ScienceMagazine) November 30, 2020
Consensus Guideline: Defining and managing COVID-19-associated pulmonary aspergillosis
15 Dec, 2020 | 01:42h | UTC
The coronavirus at 1: A year into the pandemic, what scientists know about how it spreads, infects, and sickens
15 Dec, 2020 | 01:42h | UTC
[Preprint] RECOVERY trial: Azithromycin does not improve outcomes in hospitalized patients with COVID-19
15 Dec, 2020 | 01:44h | UTCNews release: RECOVERY trial finds no benefit from azithromycin in patients hospitalised with COVID-19
Commentary on Twitter
New RECOVERY result. In patients hospitalised with COVID-19, azithromycin did not provide any clinical benefit. 28 day mortality (19% vs 19%) (rate ratio 1·00; 95% confidence interval [CI] 0·90-1·12; p=0·99). No effect on secondary outcomes either.https://t.co/PTklz40WKr pic.twitter.com/NCzvRIND0S
— Peter Horby @peterhorby.bsky.social (@PeterHorby) December 14, 2020
AHA Scientific Statement: Menopause transition and cardiovascular disease risk
15 Dec, 2020 | 01:32h | UTCNews release: Heart disease risk in women increases leading up to menopause; early intervention is key – American Heart Association
Top Things to Know: Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention
Commentaries: Menopause Transition and Cardiovascular Health: Time Matters – American Heart Association AND Report on latest menopause science looks at heart risks – American Heart Association AND Menopause Transition and CVD Risk: AHA Scientific Statement – American College of Cardiology
Randomized trial: Among women with urinary incontinence, biofeedback-mediated intensive pelvic floor training does not provide additional benefit to basic pelvic floor muscle training
15 Dec, 2020 | 01:23h | UTC
Randomized trial: Baricitinib plus remdesivir reduce recovery time in patients with COVID-19
13 Dec, 2020 | 23:31h | UTCBaricitinib plus Remdesivir for Hospitalized Adults with Covid-19 – New England Journal of Medicine
Commentary: Baricitinib plus remdesivir shows promise for treating COVID-19 – NIH News Releases
Commentary on Twitter
Not sure how to interpret a trial for a drug plus Remdesivir vs Remdesivir alone when you don't know if Remdesivir works. @NEJM today for this combo, which has already received FDA EUAhttps://t.co/tpmHPFPJX1 pic.twitter.com/Tmue99oJnV
— Eric Topol (@EricTopol) December 11, 2020
Podcast: Management of Cellulitis
15 Dec, 2020 | 01:20h | UTC
Meta-analysis: Efficacy and harms of remdesivir for the treatment of COVID-19. “Until stronger evidence emerges, we cannot conclude that remdesivir is efficacious for treating COVID-19”.
13 Dec, 2020 | 23:27h | UTC
Video: Coronavirus vaccine update with Anthony Fauci
13 Dec, 2020 | 23:25h | UTCCoronavirus Vaccine Update With Anthony Fauci – JAMA
A systematic review of corticosteroid treatment for noncritically ill patients with COVID-19 – corticosteroid treatment is not recommended for patients with mild or moderate COVID-19
13 Dec, 2020 | 23:26h | UTC
NICE Guideline: Osteoarthritis care and management
13 Dec, 2020 | 23:19h | UTCOsteoarthritis: care and management – National Institute for Health and Care Excellence


