Internal Medicine | Page 183 of 487 | Links Medicus Content Curation & Alerts in Medicine

On #LongCovid, @Dr2NisreenAlwan, a leading authority on this condition, has an exceptional perspective @ScienceMagazine today reviewing what we know, which is grossly insufficient, and what we need to do https://t.co/R7Mf5yEQCx pic.twitter.com/MNWsetLakP

— Eric Topol (@EricTopol) July 29, 2021

NICE COVID-19 rapid guideline: vaccine-induced immune thrombocytopenia and thrombosis.

30 Jul, 2021 | 12:14h | UTC

COVID-19 rapid guideline: vaccine-induced immune thrombocytopenia and thrombosis – National Institute for Health and Care Excellence

News release: NICE publishes new rapid guideline to diagnose and treat rare blood clotting condition associated with COVID-19 vaccination – National Institute for Health and Care Excellence

Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.

30 Jul, 2021 | 12:12h | UTC

Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know – Blood

Study: Patients who have recovered from COVID-19 may have persistent cognitive symptoms.

30 Jul, 2021 | 12:03h | UTC

Cognitive deficits in people who have recovered from COVID-19 – EClinicalMedicine

Commentary on Twitter (thread – click for more)

We assessed thousands and saw clear evidence of cognitive deficits in people who have recovered from COVID-19. Took a while to appease peer reviewers, but the results stand. Brilliantly led by @HampshireHub. @Amy2Jolly @JoeBarnby @srchamb @neurohellyer https://t.co/AnbhanixRk

— mitul mehta (@mehta_mitul72) July 23, 2021

Risk of acute myocardial infarction and ischemic stroke following COVID-19 in Sweden – “the true risk is increased by between three and eight times for acute myocardial infarction and by between three and seven times for ischaemic stroke following COVID-19.”

30 Jul, 2021 | 12:06h | UTC

Risk of acute myocardial infarction and ischaemic stroke following COVID-19 in Sweden: a self-controlled case series and matched cohort study – The Lancet

Invited commentary: What is the association of COVID-19 with heart attacks and strokes? – The Lancet

Commentary on Twitter

Is Covid a risk factor for heart attack and stroke?https://t.co/6KRaKzPgI5 @TheLancet
This new paper says yes, but the absolute increased risk is small, and likely due to predisposition to clotting in the post-infection phase pic.twitter.com/HQjxo63Yby

— Eric Topol (@EricTopol) July 29, 2021

Self-reported memory problems 8 months after COVID-19 infection.

30 Jul, 2021 | 12:02h | UTC

Self-reported Memory Problems 8 Months After COVID-19 Infection – JAMA Network Open

Commentary: Post-acute Sequelae of SARS-CoV-2 Infection and Subjective Memory Problems – JAMA Network Open

Commentary on Twitter (thread – click for more)

Concerning data out now in @JAMANetworkOpen about cognitive symptoms in #LongCovid among *non-hospitalized* adults.

Researchers in Norway invited 35,000 adults at the time of #coronavirus testing as well as a 20,000 person untested random sample to a prospective cohort.

(1/6) pic.twitter.com/AaU5rrwaPw

— F. Perry Wilson, MD MSCE (@fperrywilson) July 29, 2021

Israel to offer 3rd COVID booster shot to older citizens.

30 Jul, 2021 | 11:57h | UTC

Israel to offer 3rd COVID booster shot to older citizens – Associated Press

Brazilian Guidelines on Unstable Angina and Acute Myocardial Infarction without ST-Segment Elevation – 2021.

30 Jul, 2021 | 11:54h | UTC

Brazilian Society of Cardiology Guidelines on Unstable Angina and Acute Myocardial Infarction without ST-Segment Elevation – 2021 – Arquivos Brasileiros de Cardiologia (PDF)

Serious complications from youth-onset type 2 diabetes arise by young adulthood.

30 Jul, 2021 | 11:47h | UTC

Commentary: Serious complications from youth-onset type 2 diabetes arise by young adulthood – NIH News Release

Original study: Long-Term Complications in Youth-Onset Type 2 Diabetes – New England Journal of Medicine

Commentary on Twitter

High rates of complications in youth onset T2 diabetes.
Complication occurred in 60% after 13 years

Risk factors for development of complications:
Ethnic minority
Hyperglycaemia
Hypertension
Dyslipidaemia

Importance of risk factor controlhttps://t.co/UcUnuLv0PC pic.twitter.com/TfLEASSQnQ

— Prof Kamlesh Khunti (@kamleshkhunti) July 29, 2021

20-year observational study suggests return to play is manageable for most athletes with Long QT Syndrome or genetic heart diseases.

30 Jul, 2021 | 11:40h | UTC

News release: 20-year study suggests return to play is manageable for athletes with most genetic heart diseases – Mayo Clinic

Original study: Return-to-Play for Athletes With Long QT Syndrome or Genetic Heart Diseases Predisposing to Sudden Death – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries:

Return to Play Seems Safe for Most Athletes With Long QT Syndrome – HealthDay

Return-to-Play for Athletes With LQTS or Genetic Heart Diseases – American College of Cardiology

Commentary on Twitter

SO EXCITED about our 20-year review of every #athlete with #genetic #heart #disease who I have had the privilege to care of @MayoClinic @MayoClinicCV. Hopefully, this experience will spell the end of immediate disqualifications. https://t.co/574xI8aGKh

— Michael J. Ackerman MD,PhD (@MJAckermanMDPhD) July 27, 2021

Review: Changing paradigms in the management of acute uncomplicated diverticulitis.

30 Jul, 2021 | 11:37h | UTC

Changing Paradigms in the Management of Acute Uncomplicated Diverticulitis – Scandinavian Journal of Surgery

RCT: Another study shows that non-antibiotic outpatient treatment in mild acute diverticulitis is safe.

Review: Elective surgical management of diverticulitis

State of the Art Review | Management of colonic diverticulitis

Drains, germs, or steel: Multidisciplinary management of acute colonic diverticulitis

Diverticulitis: Observational study in outpatients suggests amoxicillin-clavulanate is a safe and effective option compared with metronidazole-fluoroquinolone

Randomized trial: Laparoscopic lavage vs. primary resection for perforated purulent diverticulitis; similar long-term results, but recurrence was more common after laparoscopic lavage

Randomized trial: In patients with recurrent, complicated, or persistent painful diverticulitis, sigmoid resection improved quality of life but was associated with a small but significant risk of major complications

Systematic review: Management of colonic diverticulitis

WSES Guidelines for the Management of Acute Colonic Diverticulitis

ASCRS Guidelines for the Treatment of Left-Sided Colonic Diverticulitis

Commentary on Twitter

https://twitter.com/ScandJSurg/status/1420655333815427084

Systematic review: no evidence to support the use of Ivermectin for treating or preventing COVID-19.

29 Jul, 2021 | 11:38h | UTC

Ivermectin for preventing and treating COVID‐19 – Cochrane Library

Summary: Ivermectin for preventing and treating COVID-19 – Cochrane Library

Commentary: Ivermectin treatment in humans for COVID-19 – Liverpool School of Tropical Medicine

Why was a major study on ivermectin for covid-19 just retracted?

RCT: Ivermectin does not prevent hospitalizations in patients with COVID-19.

Ivermectin for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials – “IVM did not reduce all-cause mortality, length of stay or viral clearance in RCTs in COVID-19 patients with mostly mild disease”.

Ivermectin is the new hydroxychloroquine, take 2 – “Ivermectin shouldn’t be used to treat COVID-19 outside of the context of a well-designed clinical trial”.

Therapeutics and COVID-19 | WHO guideline update advises Ivermectin should only be used to treat COVID-19 within clinical trials

RCT: Ivermectin does not improve time to resolution of symptoms among adults with mild COVID-19

PRINCIPLE RCT: Doxycycline does not improve outcomes in outpatients with suspected COVID-19 at high risk for adverse outcomes.

29 Jul, 2021 | 11:36h | UTC

Doxycycline for community treatment of suspected COVID-19 in people at high risk of adverse outcomes in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial – The Lancet Respiratory Medicine

Commentary: PRINCIPLE: a community-based COVID-19 platform trial – The Lancet Respiratory Medicine

Commentary on Twitter

https://twitter.com/LancetRespirMed/status/1420302490864603142

What is a breakthrough infection? 6 questions answered about catching COVID-19 after vaccination.

29 Jul, 2021 | 11:28h | UTC

What is a breakthrough infection? 6 questions answered about catching COVID-19 after vaccination – The Conversation

2021 ACC expert consensus decision pathway for cardiovascular risk reduction in patients with persistent hypertriglyceridemia.

29 Jul, 2021 | 11:15h | UTC

2021 ACC Expert Consensus Decision Pathway on the Management of ASCVD Risk Reduction in Patients With Persistent Hypertriglyceridemia: A Report of the American College of Cardiology Solution Set Oversight Committee – Journal of the American College of Cardiology

Key points: ACC Consensus on ASCVD Risk Reduction in Hypertriglyceridemia – American College of Cardiology

Commentary on Twitter

The ACC Expert Consensus Decision Pathway highlights 9️⃣ key points to remember on the management of atherosclerotic #CVD risk reduction in patients with persistent hypertriglyceridemia. Learn more here: https://t.co/zTx4gsIQS2 #ASCVD #cvCAD #Diabetes @virani_md @PamelaBMorris pic.twitter.com/Zjo4wmeZVj

— American College of Cardiology (@ACCinTouch) July 28, 2021

Efficacy of Pfizer/BioNTech Covid vaccine slips to 84% after six months, data show.

29 Jul, 2021 | 11:19h | UTC

Efficacy of Pfizer/BioNTech Covid vaccine slips to 84% after six months, data show – STAT

Original study (preprint): Six Month Safety and Efficacy of the BNT162b2 mRNA COVID-19 Vaccine – medRxiv

Commentary on Twitter (thread – click for more)

https://twitter.com/hildabast/status/1420481872212070404

ESC Position Paper: Cardiac, renal, and metabolic effects of SGLT2 inhibitors.

29 Jul, 2021 | 11:13h | UTC

Cardiac, renal, and metabolic effects of sodium–glucose co-transporter 2 inhibitors: a position paper from the European Society of Cardiology ad-hoc task force on sodium–glucose co-transporter 2 inhibitors – European Journal of Heart Failure

Cohort study: Postdiagnosis smoking cessation linked to reduced risk for lung cancer progression and mortality.

29 Jul, 2021 | 11:12h | UTC

Postdiagnosis Smoking Cessation and Reduced Risk for Lung Cancer Progression and Mortality: A Prospective Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Never too late: Cancer centers push patients to quit smoking – STAT

Summary for Patients: Postdiagnosis Smoking Cessation and Reduced Risk for Lung Cancer Progression and Death

Commentary on Twitter

Research led by Paul Brennan, PhD, @mahdi_iarc, et al. of @IARCWHO found that quitting smoking after a #lungcancer diagnosis may extend life without cancer recurrence https://t.co/b0YAqqt7FM. pic.twitter.com/Sjl3ipoXLQ

— Annals of Int Med (@AnnalsofIM) July 26, 2021