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Internal Medicine

Omicron Variant: Videos with opinions on the subject.

28 Nov, 2021 | 21:33h | UTC

 

Too early to tell, but preliminary information from doctors in South Africa suggests the new Covid variant Omicron may be associated with less severe disease.

28 Nov, 2021 | 21:35h | UTC

 

Screening for Lung Cancer: CHEST Guideline and Expert Panel Report.

28 Nov, 2021 | 21:22h | UTC

Executive Summary: Screening for Lung Cancer: Chest Guideline and Expert Panel Report

Full Guideline: Screening for Lung Cancer: CHEST Guideline and Expert Panel Report

News Release: CHEST releases expert guidelines for lung cancer screening – Elsevier

Related:

USPSTF Statement: begin screening for lung cancer at age 50 years instead of 55 years for patients at risk

Meta-analysis: Lung cancer screening using low-dose computed tomography reduces lung cancer–specific mortality, albeit with a tradeoff of likely overdiagnosis

 

Commentary on Twitter

 

M-A: Association of Glucagon-like Peptide 1 Analogs and agonists administered for obesity with weight loss and adverse events.

28 Nov, 2021 | 21:09h | UTC

Association of Glucagon-like Peptide 1 Analogs and Agonists Administered for Obesity with Weight Loss and Adverse Events: A Systematic Review and Network Meta-analysis – EClinicalMedicine

 

Fatigue as the chief complaint: epidemiology, causes, diagnosis, and treatment.

28 Nov, 2021 | 21:05h | UTC

Fatigue as the Chief Complaint: Epidemiology, Causes, Diagnosis, and Treatment – Deutsches Ärzteblatt International

Related: NICE Guideline | Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome: diagnosis and management.

 

2021 DORIS definition of remission in SLE: final recommendations from an international task force.

26 Nov, 2021 | 10:01h | UTC

2021 DORIS definition of remission in SLE: final recommendations from an international task force – Lupus Science & Medicine

 

Systematic Review: Quantifying anticholinergic burden and sedative load in older adults with polypharmacy.

26 Nov, 2021 | 09:58h | UTC

Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models – Drugs & Aging

 

Commentary on Twitter

 

Systematic Review: Reducing medication errors for adults in hospital settings.

26 Nov, 2021 | 09:56h | UTC

Reducing medication errors for adults in hospital settings – Cochrane Library

 

Commentary on Twitter

 

Systematic Review: Insufficient evidence to recommend Omega‐3 fatty acids for depression in adults.

26 Nov, 2021 | 09:54h | UTC

Omega‐3 fatty acids for depression in adults – Cochrane Library

 

Commentary on Twitter

 

Opinion | Things we do for no reason: prescribing appetite stimulants to hospitalized older adults with unintentional weight loss.

26 Nov, 2021 | 09:44h | UTC

Things We Do for No Reason: Prescribing Appetite Stimulants to Hospitalized Older Adults With Unintentional Weight Loss – Journal of Hospital Medicine

 

Heavily mutated coronavirus variant puts scientists on alert – “Researchers are racing to determine whether a fast-spreading variant in South Africa poses a threat to COVID vaccines’ effectiveness”.

26 Nov, 2021 | 08:42h | UTC

Heavily mutated coronavirus variant puts scientists on alert – Nature

See also:

Covid: New heavily mutated variant B.1.1.529 in South Africa raises concern – BBC

WHO calls special meeting to discuss new Covid variant found in South Africa with ‘a large number of mutations’ – CNBC

New COVID-19 Variant With Multiple Concerning Mutations Identified in Southern Africa – Health Policy Watch

Scientists warn of new Covid variant with high number of mutations – The Guardian

South Africa detects new COVID variant with many mutations – MedicalXpress

 

Related commentary on Twitter (thread – click for more)

 

Review: Prevention and management of thrombosis in hospitalized patients with COVID-19 pneumonia.

26 Nov, 2021 | 08:44h | UTC

Prevention and management of thrombosis in hospitalised patients with COVID-19 pneumonia – The Lancet Respiratory Medicine

 

[Preprint] Serological responses to COVID-19 booster vaccine in England.

26 Nov, 2021 | 08:34h | UTC

Serological responses to COVID-19 booster vaccine in England – medRxiv

 

Commentary from the author on Twitter (thread – click for more)

 

A population-based cohort study in Qatar showed reinfections had 90% lower odds of resulting in hospitalization or death than primary infections.

25 Nov, 2021 | 10:46h | UTC

Severity of SARS-CoV-2 Reinfections as Compared with Primary Infections – New England Journal of Medicine

Related: [Preprint] M-A of 12.011.447 individuals finds individuals previously infected with SARS-CoV-2 had an 81% reduction in odds of a reinfection.

 

Guideline for the laboratory diagnosis of iron deficiency in adults (excluding pregnancy) and children.

25 Nov, 2021 | 10:31h | UTC

Guideline for the laboratory diagnosis of iron deficiency in adults (excluding pregnancy) and children – British Journal of Haematology

 

Systematic Review: Macrolides versus placebo for chronic asthma.

25 Nov, 2021 | 10:14h | UTC

Macrolides versus placebo for chronic asthma – Cochrane Library

 

Commentary on Twitter

 

Diets for weight management in adults with type 2 diabetes: an umbrella review of published meta-analyses and systematic review of trials of diets for diabetes remission – “Published meta-analyses of hypocaloric diets for weight management in people with type 2 diabetes do not support any particular macronutrient profile or style over others”.

25 Nov, 2021 | 10:19h | UTC

Diets for weight management in adults with type 2 diabetes: an umbrella review of published meta-analyses and systematic review of trials of diets for diabetes remission – Diabetologia

News Release: Analysis shows low energy diets with formula meal replacements are the most effective methods for weight management and remission in adults with type 2 diabetes – Diabetologia

 

Commentary on Twitter

https://twitter.com/DiabetologiaJnl/status/1461773268231147521

 

M-A: Incidence, prevalence and determinants of discomfort in inflammatory bowel disease.

25 Nov, 2021 | 09:54h | UTC

Systematic Review and Meta-analysis on the Incidence, Prevalence and Determinants of Discomfort in Inflammatory Bowel Disease – Journal of the Canadian Association of Gastroenterology

 

Cohort study found the risk of myocardial infarction may be best predicted by the number of apolipoprotein B containing lipoproteins.

24 Nov, 2021 | 08:41h | UTC

Association of Apolipoprotein B–Containing Lipoproteins and Risk of Myocardial Infarction in Individuals With and Without Atherosclerosis: Distinguishing Between Particle Concentration, Type, and Content – JAMA Cardiology (link to abstract – $ for full-text)

Commentaries:

ApoB Gains Ground as Best Lipid Predictor of MI Risk – TCTMD

Study finds risk of MI best captured by number of apolipoprotein B lipoproteins – MedicalResearch

 

Commentary on Twitter

 

Review: COVID-19-associated Invasive Fungal Infection.

24 Nov, 2021 | 08:48h | UTC

COVID-19-associated Invasive Fungal Infection – Open Forum Infectious Diseases

Related:

Taskforce report on the diagnosis and clinical management of COVID-19 associated pulmonary aspergillosis.

M-A: Incidence and mortality of COVID‐19‐associated pulmonary aspergillosis – The incidence and mortality in the ICU were estimated to be 10.2% and 54.9%, respectively.

Consensus Guideline: Defining and managing COVID-19-associated pulmonary aspergillosis

Bacterial and fungal superinfections in critically ill patients with COVID-19

Invasive Fungal Disease complicating COVID-19: when it rains it pours

A national strategy to diagnose COVID-19 associated invasive fungal disease in the ICU

Epidemiology of invasive pulmonary aspergillosis among COVID-19 intubated patients

 

Commentary on Twitter

 

AGA Clinical practice update on management of chronic gastrointestinal pain in disorders of gut–brain interaction.

24 Nov, 2021 | 08:42h | UTC

AGA Clinical Practice Update on Management of Chronic Gastrointestinal Pain in Disorders of Gut–Brain Interaction: Expert Review – Clinical Gastroenterology and Hepatology

 

Viewpoint: The growing phenomenon of “virtual-first” primary care.

24 Nov, 2021 | 08:39h | UTC

The Growing Phenomenon of “Virtual-First” Primary Care – JAMA (free for a limited period)

 

We expected people with asthma to fare worse during COVID. Turns out they’ve had a break.

24 Nov, 2021 | 08:44h | UTC

We expected people with asthma to fare worse during COVID. Turns out they’ve had a break – The Conversation

 

Safety analysis of RCTs showed Alzheimer’s drug Aducanumab caused brain swelling in 35% of patients, and 26.0% experienced associated symptoms (e.g., headache, confusion, dizziness, and nausea).

24 Nov, 2021 | 08:35h | UTC

Amyloid-Related Imaging Abnormalities in 2 Phase 3 Studies Evaluating Aducanumab in Patients With Early Alzheimer Disease – JAMA Neurology

Commentary: Biogen Alzheimer’s drug shows brain swelling in 35% of patients – MedicalXpress

 

Commentary on Twitter

 

Three Neurologic Societies, Including the AAN, Issue Strong Position Statement on Aducanumab.

24 Nov, 2021 | 08:36h | UTC

Three Neurologic Societies, Including the AAN, Issue Strong Position Statement on Aducanumab – Neurology Today

See statement: Decisions With Patients and Families Regarding Aducanumab in Alzheimer Disease, With Recommendations for Consent: AAN Position Statement – Neurology

Related:

Editorial: Aducanumab for Alzheimer’s disease?

FDA approvement of Alzheimer’s drug sparks controversy among doctors.

 

Commentary on Twitter

 

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