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Internal Medicine

Cohort Study | Habitual calcium supplementation linked to higher CVD incidence and mortality in diabetics

8 Aug, 2023 | 13:24h | UTC

Associations of Habitual Calcium Supplementation With Risk of Cardiovascular Disease and Mortality in Individuals With and Without Diabetes – Diabetes Care (link to abstract – $ for full-text)

Related: The Evidence and Controversy Between Dietary Calcium Intake and Calcium Supplementation and the Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Cohort Studies and Randomized Controlled Trials – Journal of the American College of Nutrition

 

Commentary on Twitter

 


NICE Updated Guideline | Venous thromboembolic diseases

7 Aug, 2023 | 15:05h | UTC

Venous thromboembolic diseases: diagnosis, management and thrombophilia testing  – National Institute for Health and Care Excellence

 


Review | Management of worsening heart failure with reduced ejection fraction

7 Aug, 2023 | 15:03h | UTC

Management of Worsening Heart Failure With Reduced Ejection Fraction: JACC Focus Seminar 3/3 – Journal of the American College of Cardiology

 

Commentary on Twitter

 


Cohort Study | High-sensitivity troponin’s role in assessing MI and CV death risk in stable CAD patients

7 Aug, 2023 | 15:01h | UTC

High-Sensitivity Cardiac Troponin for Risk Assessment in Patients With Chronic Coronary Artery Disease – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries:

High-Sensitivity Troponin Assays May Stratify Risk in Chronic CAD – TCTMD

High-Sensitivity Cardiac Troponin for Risk Assessment in Chronic CAD – Journal of the American College of Cardiology

 

Commentary on Twitter

 


Opinion | Regulating direct-to-consumer polygenic risk scores

7 Aug, 2023 | 14:59h | UTC

Regulating Direct-to-Consumer Polygenic Risk Scores – JAMA (free for a limited period)

 


Perspective | The paradoxical decline of geriatric medicine as a profession

7 Aug, 2023 | 14:57h | UTC

The Paradoxical Decline of Geriatric Medicine as a Profession – JAMA (free for a limited period)

 

Commentary on Twitter

 


Expert Panel | Assessment and management of older adults undergoing percutaneous coronary intervention

7 Aug, 2023 | 14:55h | UTC

Assessment and Management of Older Adults Undergoing PCI, Part 1: A JACC: Advances Expert Panel – Journal of the American College of Cardiology

A Geriatric Approach to Percutaneous Coronary Interventions in Older Adults, Part II: A JACC: Advances Expert Panel – Journal of the American College of Cardiology

 


ESPEN guideline on nutritional support for polymorbid medical inpatients

7 Aug, 2023 | 14:52h | UTC

ESPEN guideline on nutritional support for polymorbid medical inpatients – Clinical Nutrition

 


Review | Cardiorenal syndrome in the hospital

7 Aug, 2023 | 14:36h | UTC

Cardiorenal Syndrome in the Hospital – Clinical Journal of the American Society of Nephrology

 

Commentary on Twitter

 

 


Review | Diabetes of the exocrine pancreas: implications for pharmacological management

7 Aug, 2023 | 14:25h | UTC

Diabetes of the Exocrine Pancreas: Implications for Pharmacological Management – Drugs

 


Study | Gastric bypass linked to increased risk of non-alcohol substance use disorder

7 Aug, 2023 | 14:23h | UTC

Non-alcohol substance use disorder after bariatric surgery in the prospective, controlled Swedish Obese Subjects study – Obesity

News Release: Gastric bypass surgery associated with non-alcohol substance use disorder – Obesity – The Obesity Society

 


RCT | 52-week antidepressant adjunctive therapy did not lead to a statistically significant benefit over 8-week therapy in bipolar I depression

4 Aug, 2023 | 12:11h | UTC

Duration of Adjunctive Antidepressant Maintenance in Bipolar I Depression – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Modern antidepressants may reduce risk of relapse for patients with bipolar depression – University of British Columbia

 

Commentary on Twitter

 


Study | Removal of thymus in adults linked to increased death, cancer incidence

4 Aug, 2023 | 12:09h | UTC

Health Consequences of Thymus Removal in Adults – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

Doctors have long considered the thymus expendable. But could removing it be fatal? – Science

The thymus withers away after puberty. But it may be important for adults – Science News

Thymus gland critical for adult health, study finds – News Medical

 

Commentary on Twitter

 


Review | Primary aldosteronism: a pragmatic approach to diagnosis and management

4 Aug, 2023 | 12:06h | UTC

Primary Aldosteronism: A Pragmatic Approach to Diagnosis and Management – Mayo Clinic Proceedings

 


KDIGO Conference | Managing the symptom burden associated with maintenance dialysis

4 Aug, 2023 | 12:02h | UTC

Managing the symptom burden associated with maintenance dialysis: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference – Kidney International

News Release: KDIGO Announces Publication of “Managing the Symptom Burden Associated with Maintenance Dialysis”

 

Commentary on Twitter

 


Perspective | Cardiac device infection: removing barriers to timely and adequate treatment

4 Aug, 2023 | 11:54h | UTC

Cardiac device infection: removing barriers to timely and adequate treatment – European Heart Journal

 


Brief Review | How do I diagnose and treat my patient’s amiodarone-induced thyrotoxicosis?

4 Aug, 2023 | 11:52h | UTC

How do I diagnose and treat my patient’s amiodarone-induced thyrotoxicosis? – Cleveland Clinic Journal of Medicine

 


Review | Diagnosis and management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome

4 Aug, 2023 | 11:50h | UTC

Diagnosis and management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome – Cleveland Clinic Journal of Medicine

 


Review | Autoimmunity and postural orthostatic tachycardia syndrome: Implications in diagnosis and management

4 Aug, 2023 | 11:49h | UTC

Autoimmunity and postural orthostatic tachycardia syndrome: Implications in diagnosis and management – Cleveland Clinic Journal of Medicine

 


ACP Guidance | Asymptomatic CRC screening advised from age 50 with fecal occult blood test every 2 years or colonoscopy every 10 years

3 Aug, 2023 | 13:48h | UTC

Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults: A Guidance Statement From the American College of Physicians – Annals of Internal Medicine

News Release: ACP issues updated guidance for colorectal cancer screening of asymptomatic adults – American College of Physicians

Commentary: Start screening for colorectal cancer at age 50 years, ACP suggests – ACP Internist

Summary for Patients: Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults – Annals of Internal Medicine

 


RCT – 2ry analysis | Omega-3 supplementation linked to increased AF risk in post-MI patients

3 Aug, 2023 | 13:45h | UTC

Omega-3 fatty acid supplements and risk of atrial fibrillation and ‘micro-atrial fibrillation’: A secondary analysis from the OMEMI trial – Clinical Nutrition

Related:

M-A: Omega-3 fatty acids supplementation is associated with increased risk of atrial fibrillation.

M-A: Omega-3 fatty acids supplementation increases the risk of atrial fibrillation in patients with lipid disorders.

More data suggests no cardiovascular benefit from Omega-3 supplementation – secondary analysis of STRENGHT trial did not show an association between achieved Omega-3 fatty acid levels and major adverse cardiovascular outcomes in patients with high cardiovascular risk.

RCT: Omega-3 supplements do not reduce cardiovascular events in elderly patients after myocardial infarction

#AHA20 – Randomized trial: High-dose Omega-3 fatty acids did not reduce the risk of cardiac events in patients at high cardiovascular risk

Meta-Analysis of Randomized Trials: Little Benefit from Omega-3 Intake to Reduce Cardiovascular Disease Risk

 

Commentary from the author on Twitter (thread – click for more)

 


Cohort Study | Increased mortality rates in delirium tremens patients versus alcohol withdrawal or dependence

3 Aug, 2023 | 13:35h | UTC

Mortality and alcohol-related morbidity in patients with delirium tremens, alcohol withdrawal state or alcohol dependence in Norway: A register-based prospective cohort study – Addiction

 


Study | Increasing alcohol-related mortality rates in US women, 1999-2020

3 Aug, 2023 | 13:20h | UTC

Trends in Alcohol-Related Deaths by Sex in the US, 1999-2020 – JAMA Network Open

Commentary: As alcohol-related deaths rise in the US, women are increasingly at risk, study shows – CNN

 


RCT | Early oral antibiotic switch in low-risk neutropenic sepsis shows mixed results

3 Aug, 2023 | 13:15h | UTC

Early switch to oral antibiotic therapy in patients with low risk neutropenic sepsis (EASI-SWITCH): A randomized non-inferiority trial – Clinical Microbiology and Infection

 


Review | Diagnosing delirium in perioperative and intensive care medicine

3 Aug, 2023 | 13:09h | UTC

Diagnosing delirium in perioperative and intensive care medicine – Current Opinion in Anesthesiology

 


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