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Internal Medicine

Dyspepsia: A stepwise approach to evaluation and management.

19 Jan, 2022 | 08:24h | UTC

Dyspepsia: A stepwise approach to evaluation and management – Family Practice

 


Opinion: Five tips for becoming an ideal general hospitalist.

19 Jan, 2022 | 08:23h | UTC

Five Tips for Becoming an Ideal General Hospitalist – International Journal of General Medicine

 


[Not published yet] Study in Israel finds fourth COVID booster has limited efficacy.

18 Jan, 2022 | 09:59h | UTC

Israel Finds Fourth COVID Booster is Ineffective, While Hospitalised Omicron Patients Fare Much Better Than Delta Patients – Health Policy Watch

See also:

Israeli trial, world’s first, finds 4th dose ‘not good enough’ against Omicron – The Times of Israel

Israel study: 4th vaccine shows limited results with omicron – MedicalXpress

 


COVID-19 updated evidence: a Cochrane round-up.

18 Jan, 2022 | 09:53h | UTC

COVID-19 evidence: a Cochrane round-up – Cochrane Library

 


Time to upgrade from cloth and surgical masks to respirators? Your questions answered.

18 Jan, 2022 | 09:48h | UTC

Time to upgrade from cloth and surgical masks to respirators? Your questions answered – The Conversation

See also: The CDC updated its mask guidelines. What to know about ‘the highest level of protection’ – CNN

Related: CDC urges Americans to wear most-protective mask or respirator that fits well and that they’ll wear consistently.

 


Study raises doubts about rapid Covid tests’ reliability in early days after infection.

18 Jan, 2022 | 09:51h | UTC

Study raises doubts about rapid Covid tests’ reliability in early days after infection – STAT

Original Article (preprint): Discordant SARS-CoV-2 PCR and Rapid Antigen Test Results When Infectious: A December 2021 Occupational Case Series – medRxiv

 


Case series of Thrombosis with Thrombocytopenia Syndrome after Covid-19 vaccination in the US.

18 Jan, 2022 | 09:41h | UTC

Case Series of Thrombosis With Thrombocytopenia Syndrome After COVID-19 Vaccination—United States, December 2020 to August 2021 – Annals of Internal Medicine

Editorial: The Epidemiology of Thrombosis With Thrombocytopenia Syndrome: Analogies With Heparin-Induced Thrombocytopenia – Annals of Internal Medicine

 


Perspective | Post-acute neurological consequences of COVID-19: an unequal burden – “COVID-19 and its neurological consequences particularly burden marginalized communities, and so can only be effectively treated by advancing health equity”.

18 Jan, 2022 | 09:44h | UTC

Post-acute neurological consequences of COVID-19: an unequal burden – Nature Medicine

 


Pro-Con Debate: Cardiac Troponin measurement as part of routine follow-up of myocardial damage following noncardiac surgery.

18 Jan, 2022 | 09:36h | UTC

Pro-Con Debate: Cardiac Troponin Measurement as Part of Routine Follow-up of Myocardial Damage Following Noncardiac Surgery – Anesthesia & Analgesia

 


ACP Guideline: Diagnosis and management of acute left-sided colonic diverticulitis.

18 Jan, 2022 | 09:38h | UTC

Diagnosis and Management of Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

Related Guideline: Colonoscopy for Diagnostic Evaluation and Interventions to Prevent Recurrence After Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

Related Systematic Reviews:

Diagnostic Imaging and Medical Management of Acute Left-Sided Colonic Diverticulitis: A Systematic Review – Annals of Internal Medicine

Evaluation and Management After Acute Left-Sided Colonic Diverticulitis: A Systematic Review – Annals of Internal Medicine

Annals Video Summary: Diagnostic Imaging and Medical Management of Acute Left-Sided Colonic Diverticulitis: A Systematic Review – Annals of Internal Medicine

News Release: ACP releases two new clinical guidelines on the diagnosis and management of diverticulitis – American College of Physicians

 


Podcast: Lower Extremity Edema Pearls.

18 Jan, 2022 | 09:33h | UTC

#316 Lower Extremity Edema – The Curbsiders

 


Review: Myocardial infarction with non-obstructive coronary artery disease.

18 Jan, 2022 | 09:24h | UTC

Myocardial infarction with non-obstructive coronary artery disease – EuroIntervention

Related:

MINOCA from A to Z – American College of Cardiology

Guidelines for the Management of Myocardial Infarction/injury with Non-obstructive Coronary Arteries (MINOCA)

Prognosis and Predictors of Mortality in Patients Suffering Myocardial Infarction With Non‐Obstructive Coronary Arteries

Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease: A Scientific Statement From the American Heart Association

The What, When, Who, Why, How and Where of Myocardial Infarction With Non-Obstructive Coronary Arteries (MINOCA) – Circulation Journal

Systematic Review of Patients Presenting With Suspected Myocardial Infarction and Nonobstructive Coronary Arteries – Circulation

Nonobstructive Versus Obstructive Coronary Artery Disease in Acute Coronary Syndrome: A Meta‐Analysis – Journal of the American Heart Association

 


A national cohort study in Sweden showed pregnancy complications (preeclampsia or eclampsia, gestational hypertension, gestational diabetes, preterm birth, small for gestational age, and stillbirth) are associated with increased risk of cardiovascular disease later in life.

18 Jan, 2022 | 09:26h | UTC

Pregnancy Complications and Risk of Cardiovascular Disease Later in Life: A Nationwide Cohort Study – Journal of the American Heart Association

 


Cohort study: In patients who underwent bariatric surgery, those submitted to gastric bypass were slightly more likely to remain free of obesity-related medications during follow-up compared with those who underwent sleeve gastrectomy.

18 Jan, 2022 | 09:31h | UTC

Medication Use for Obesity-Related Comorbidities After Sleeve Gastrectomy or Gastric Bypass – JAMA Surgery (link to abstract – $ for full-text)

Commentary: Gastric Bypass Tied to Modest Shift in Need for Comorbidity Meds – MedPage Today (free registration required)

 

Commentary on Twitter

 


WHO recommends two new drugs (Baricitinib and Sotrovimab) to treat COVID-19.

17 Jan, 2022 | 00:48h | UTC

News release: WHO recommends two new drugs to treat COVID-19 – World Health Organization

Infographic with the updated recommendations: A living WHO guideline on drugs for covid-19 – The BMJ

Commentaries:

WHO Recommends Two New COVID-19 Treatments – Cost and Availability Likely Barriers – Health Policy Watch

Expert reaction to WHO recommending two drugs, sotrovimab and baricitinib, to treat patients with COVID-19 – Science Media Centre

 

Commentary on Twitter (thread – click for more)

 


Viewpoint: COVID-19 therapeutics for nonhospitalized patients.

17 Jan, 2022 | 00:31h | UTC

COVID-19 Therapeutics for Nonhospitalized Patients – JAMA

Editorial: Realizing the Potential of Anti–SARS-CoV-2 Monoclonal Antibodies for COVID-19 Management – JAMA

 


One in 10 people may still be infectious for COVID after 10 days, new research indicates.

17 Jan, 2022 | 00:34h | UTC

News Release: One in 10 people may still be infectious for COVID after 10 days, new research indicates – University of Exeter

Original article: Persistence of clinically relevant levels of SARS-CoV2 envelope gene subgenomic RNAs in non-immunocompromised individuals – International Journal of Infectious Diseases

Commentary: Expert reaction to study looking at clinically relevant levels of potentially active virus 10 days after a positive PCR test – Science Media Centre

 


2022 Guidelines on the management of chronic venous disease of the lower limbs.

16 Jan, 2022 | 23:22h | UTC

European Society for Vascular Surgery (ESVS) 2022 Clinical Practice Guidelines on the Management of Chronic Venous Disease of the Lower Limbs – European Journal of Vascular & Endovascular Surgery

 


RCT: Oral Vitamin D supplementation (60.000 IU per month) did not reduce mortality in patients 60 years or older (unscreened individuals in Australia, many without insufficiency, average 30ng/mL). Exploratory analyses pointed towards an increased risk of death from cancer.

16 Jan, 2022 | 23:13h | UTC

The D-Health Trial: a randomised controlled trial of the effect of vitamin D on mortality – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Related:

Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease

Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention

Association between vitamin D supplementation and mortality: systematic review and meta-analysis – The BMJ

USPSTF Draft Statement: Insufficient evidence to recommend multivitamin supplements for the prevention of CVD or cancer. The statement also recommends against the use of beta-carotene (increases risk of CVD mortality and lung cancer) or vitamin E (clear evidence of no benefit)

Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases

Research: Circulating vitamin D concentration and risk of seven cancers

Research: Vitamin D and risk of total and site specific cancers

 


ERAS Guidelines for perioperative care in bariatric surgery.

16 Jan, 2022 | 23:21h | UTC

Guidelines for Perioperative Care in Bariatric Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations: A 2021 Update – World Journal of Surgery

Related: Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines

 

Commentary on Twitter

 


RCT: Vitamin D supplementation is not beneficial for the prevention of cardiovascular disease and cancer.

16 Jan, 2022 | 23:11h | UTC

Vitamin D supplementation and prevention of cardiovascular disease and cancer in the Finnish Vitamin D Trial-a randomized controlled trial – American Journal of Clinical Nutrition

News Release: Five years of high-dose vitamin D did not affect incidence of cardiovascular disease or cancer – University of Eastern Finland

Related:

Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease

Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention

Association between vitamin D supplementation and mortality: systematic review and meta-analysis – The BMJ

USPSTF Draft Statement: Insufficient evidence to recommend multivitamin supplements for the prevention of CVD or cancer. The statement also recommends against the use of beta-carotene (increases risk of CVD mortality and lung cancer) or vitamin E (clear evidence of no benefit)

Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases

Research: Circulating vitamin D concentration and risk of seven cancers

Research: Vitamin D and risk of total and site specific cancers

 


Perspective: Primary care providers should prescribe aspirin to prevent cardiovascular disease based on benefit−risk ratio, not age.

16 Jan, 2022 | 22:53h | UTC

Primary care providers should prescribe aspirin to prevent cardiovascular disease based on benefit−risk ratio, not age – Family Medicine and Community Health

Commentaries:

Researchers urge: ‘Prescribe aspirin based on benefit-to-risk not age’ – Florida Atlantic University

Preventive Aspirin Should Be Based on Benefit, Not Age – HealthDay

Related: USPSTF draft statement revises previous guidance and now recommends against initiating low-dose aspirin use for the primary prevention of CVD in adults aged 60 years or older.

 


Cluster randomized trial: no added value of duloxetine for patients with chronic pain due to hip or knee osteoarthritis.

16 Jan, 2022 | 22:59h | UTC

No added value of duloxetine for patients with chronic pain due to hip or knee osteoarthritis: a cluster randomised trial – Arthritis & Rheumatism

 


Analysis: Sarcopenia: early prevention or overdiagnosis?

16 Jan, 2022 | 22:48h | UTC

Sarcopenia: early prevention or overdiagnosis? – The BMJ

Related: Overdiagnosis: it’s official – the term is now included in the medical subject headings (MeSH) vocabulary. (several articles on the subject)

 

Commentary from the author on Twitter

 


Review | Travelling with heart failure: risk assessment and practical recommendations.

16 Jan, 2022 | 22:46h | UTC

Travelling with heart failure: risk assessment and practical recommendations – Nature Reviews Cardiology (if this link is paywalled, try this one)

 


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