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Internal Medicine

M-A: Comparative effectiveness of statins on non-HDL cholesterol in people with diabetes and at risk of cardiovascular disease.

25 Mar, 2022 | 10:01h | UTC

Comparative effectiveness of statins on non-high density lipoprotein cholesterol in people with diabetes and at risk of cardiovascular disease: systematic review and network meta-analysis – The BMJ

News Release: Best statins for reducing cardiovascular risk in people with diabetes found – University of Manchester

 

Commentary on Twitter

 


Review: How to improve compliance to hypertension treatment.

28 Mar, 2022 | 08:31h | UTC

How to improve compliance to hypertension treatment – European Society of Cardiology

 

Commentary on Twitter

 


Cochrane Special Collection: Diagnosing tuberculosis.

25 Mar, 2022 | 09:57h | UTC

Diagnosing tuberculosis – Cochrane Library

 


3 orthopedic surgeries that might be doing patients (and their pockets) more harm than good.

25 Mar, 2022 | 09:54h | UTC

3 orthopaedic surgeries that might be doing patients (and their pockets) more harm than good – The Conversation

 


Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study.

25 Mar, 2022 | 09:56h | UTC

Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study – PLOS Medicine

Commentaries:

Sweeteners may be linked to increased cancer risk – new research – The Conversation

Expert reaction to observational study of sweeteners and cancer risk – Science Media Centre

 


Review: Tobacco and nicotine use.

25 Mar, 2022 | 08:49h | UTC

Tobacco and nicotine use – Nature Reviews Disease Primers (if the link is paywalled, try this one)

Infographic: Tobacco and nicotine use (if the link is paywalled, try this one)

 

Commentary on Twitter

https://twitter.com/DiseasePrimers/status/1507089870950318118

 


[Preprint] RCT: Vitamin D supplements did not prevent Covid-19 or other acute respiratory infections.

25 Mar, 2022 | 09:49h | UTC

Vitamin D Supplements for Prevention of Covid-19 or other Acute Respiratory Infections: a Phase 3 Randomized Controlled Trial (CORONAVIT) – medRxiv

Related:

M-A: Low vitamin D levels do not aggravate COVID-19 risk or death, and vitamin D supplementation does not improve outcomes in hospitalized patients with COVID-19.

In a Mendelian randomization study, researchers found no genetic evidence to support an association between Vitamin D levels and COVID-19 susceptibility, severity, or hospitalization.

Living systematic review: The evidence is insufficient to determine the benefits and harms of vitamin D supplementation as a treatment of COVID‐19.

RCT: Vitamin D3 does not improve outcomes in hospitalized patients with moderate to severe COVID-19

 

Commentary on Twitter (thread – click for more)

https://twitter.com/KarlPfleger/status/1506871284214337543

 


Review: Surgical risk assessment in patients with chronic liver diseases.

25 Mar, 2022 | 08:46h | UTC

Surgical Risk Assessment in Patients With Chronic Liver Diseases – Journal of Clinical and Experimental Hepatology

 

Commentary on Twitter

 


The Role of Cardioprotection in Cancer Therapy Cardiotoxicity: JACC: CardioOncology State-of-the-Art Review.

25 Mar, 2022 | 08:51h | UTC

The Role of Cardioprotection in Cancer Therapy Cardiotoxicity: JACC: CardioOncology State-of-the-Art Review – JACC: CardioOncology

 


RCT: In patients with chronic migraine and overuse of symptomatic medications, migraine preventive therapy without switching or limiting the frequency of the overused medication was non-inferior to switching to a different symptomatic medication with a maximum limit of two treatment days/week.

25 Mar, 2022 | 08:44h | UTC

Patient-Centered Treatment of Chronic Migraine With Medication Overuse: A Prospective, Randomized, Pragmatic Clinical Trial – Neurology (link to abstract – $ for full-text)

 


M-A: Staphylococcus aureus bacteremia mortality.

25 Mar, 2022 | 08:36h | UTC

Staphylococcus aureus bacteremia mortality: A systematic review and meta-analysis – Clinical Microbiology and Infection

 


M-A: Tuberculosis screening among HIV-positive inpatients.

25 Mar, 2022 | 08:35h | UTC

Tuberculosis screening among HIV-positive inpatients: a systematic review and individual participant data meta-analysis – The Lancet HIV

 

Commentary on Twitter

https://twitter.com/CarlosdelRio7/status/1506893108864335872

 


Observational study suggests antidopaminergic antiemetics (domperidone, metopimazine, and metoclopramide) are associated with increased stroke risk.

24 Mar, 2022 | 09:51h | UTC

Risk of first ischaemic stroke and use of antidopaminergic antiemetics: nationwide case-time-control study – The BMJ

News Release: Widely used nausea drugs linked to heightened risk of stroke – BMJ

 


RCT: Single-dose Liposomal Amphotericin B treatment for Cryptococcal Meningitis.

24 Mar, 2022 | 09:56h | UTC

Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Systematic Review: Effectiveness and safety of pulse oximetry in remote patient monitoring of patients with COVID-19.

24 Mar, 2022 | 08:53h | UTC

Effectiveness and safety of pulse oximetry in remote patient monitoring of patients with COVID-19: a systematic review – The Lancet Digital Health

Commentaries:

Home blood oxygen monitoring can help COVID patients spot early warning signs – Imperial College London

Simple home oxygen monitors signal when to seek COVID care – CIDRAP

 


RCT: Awake prone positioning did not improve outcomes in patients with moderate hypoxemia due to covid-19.

24 Mar, 2022 | 09:48h | UTC

Prone positioning of patients with moderate hypoxaemia due to covid-19: multicentre pragmatic randomised trial (COVID-PRONE) – The BMJ

Editorial: Awake prone positioning for patients with covid-19

News Release: Lying prone long enough to improve outcomes is difficult for many covid-19 patients – BMJ

 


Guideline: Evaluation and medical management of the kidney stone patient.

24 Mar, 2022 | 08:46h | UTC

Update – 2022 Canadian Urological Association guideline: Evaluation and medical management of the kidney stone patient – Canadian Urological Association Journal

Related Guidelines:

Canadian Urological Association guideline: Management of ureteral calculi – Abridged version – Canadian Urological Association Journal

Renal and ureteric stones: assessment and management – National Institute for Health and Care Excellence

Dietary and Pharmacologic Management to Prevent Recurrent Nephrolithiasis in Adults: A Clinical Practice Guideline From the American College of Physicians

Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement – Journal of Nephrology

The Urological Association of Asia clinical guideline for urinary stone disease – International Journal of Urology

 


RCT: Multivitamins not beneficial for the prevention of cancer.

24 Mar, 2022 | 08:49h | UTC

Multivitamins in the prevention of cancer and cardiovascular disease: The COSMOS randomized clinical trial – American Journal of Clinical Nutrition

Commentary: Daily Multivitamin Does Not Cut Cancer Incidence in Older Adults – HealthDay

Related: USPSTF Draft Statement: Insufficient evidence to recommend multivitamin supplements for the prevention of CVD or cancer. The statement also recommends against the use of beta-carotene (increases risk of CVD mortality and lung cancer) or vitamin E (clear evidence of no benefit)

 


Delirium linked to increase in hospital deaths.

24 Mar, 2022 | 08:24h | UTC

News Release: Delirium linked to increase in hospital deaths – University of Edinburgh

Original Study: Positive scores on the 4AT delirium assessment tool at hospital admission are linked to mortality, length of stay and home time: two-centre study of 82,770 emergency admissions – Age and Ageing

 

Commentary on Twitter

 


Clinical approach to vision loss: a review for general physicians.

24 Mar, 2022 | 08:09h | UTC

Clinical approach to vision loss: a review for general physicians – Clinical Medicine Journal

 


Biomarkers may be an early warning sign for the presence of giant cell arteritis in patients with polymyalgia rheumatica.

24 Mar, 2022 | 08:17h | UTC

Angiopoietin-2/-1 ratios and MMP-3 levels as an early warning sign for the presence of giant cell arteritis in patients with polymyalgia rheumatica – Arthritis Research & Therapy

Commentary: Biomarkers may improve giant cell arteritis diagnosis – medwireNews

 

Commentary on Twitter

 


Diabetic retinopathy for the non-ophthalmologist.

24 Mar, 2022 | 08:07h | UTC

Diabetic retinopathy for the non-ophthalmologist – Clinical Medicine Journal

 


Inflammatory eye disease: An overview of clinical presentation and management.

24 Mar, 2022 | 08:07h | UTC

Inflammatory eye disease: An overview of clinical presentation and management – Clinical Medicine Journal

 


An update on the clinical approach to giant cell arteritis.

24 Mar, 2022 | 08:03h | UTC

An update on the clinical approach to giant cell arteritis – Clinical Medicine Journal

 


Diplopia: Diagnosis and management.

24 Mar, 2022 | 08:04h | UTC

Diplopia: Diagnosis and management – Clinical Medicine Journal

 


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